Frontiers in Neurology | Dementia and Neurodegenerative Diseases

Original Research

Published on 16 Oct 2025

The exploration of using plasma biomarkers of p-tau217 and p-tau181 for screening Alzheimer’s disease in very elderly people

in Dementia and Neurodegenerative Diseases

Shouzi Zhang
Haiyan Wu
Li Ma
Rui Li
Li Zhang
Lixin Liu
Xuelin He
Tingyu Zhao

Frontiers in Neurology

doi 10.3389/fneur.2025.1668512

2,460 views

Correction

Published on 13 Oct 2025

Correction: Cognitive profile and frailty in patients with idiopathic normal pressure hydrocephalus

in Dementia and Neurodegenerative Diseases

Magnhild S. Dejgaard
Per Kristian Eide
Gro Gujord Tangen
Eva Skovlund
Geir Selbæk
Torgeir Bruun Wyller

Frontiers in Neurology

doi 10.3389/fneur.2025.1708210

865 views

Clinical Trial

Published on 08 Oct 2025

Adipose-derived mesenchymal stem cells for the treatment of Amyotrophic Lateral Sclerosis. A phase I/II safety and efficacy clinical trial

in Dementia and Neurodegenerative Diseases

Eduardo Agüera-Morales
Victoria Eugenia Fernández-Sánchez
Guillermo Navarro-Mascarell
Juan Antonio Cabezas-Rodríguez
María Ángeles Peña-Toledo
Virginia Reyes-Garrido
María José Postigo-Pozo
Giorgio Patrignani-Ochoa
María Ángeles Geniz-Clavijo
Celedonio Márquez-Infante

Frontiers in Neurology

doi 10.3389/fneur.2025.1655124

2,514 views

Systematic Review

Published on 03 Oct 2025

Review of the evidence on the influence of Wi-Fi 2.4 GHz radiation on oxidative stress and its possible relationship with Alzheimer’s disease

in Dementia and Neurodegenerative Diseases

David Laván
Natalia Argüelles
Alexis Lluncor
Daniel Huaman
Juan Moyano
Jorge Ubillus
Milton Peña
Mónica Paredes
Iván Hernández
Alcides Guerra

Frontiers in Neurology

doi 10.3389/fneur.2025.1616435

4,973 views

Systematic Review

Published on 02 Oct 2025

Effects of different physical activity interventions on executive function in older adults with dementia: a systematic review and network meta-analysis

in Dementia and Neurodegenerative Diseases

Ying Zhu
Shuang Li
Zixian Xiao
Hongyu Wang
Xiaolin Zhang
Qianqian Huang
Rui Yin
Kelei Guo
Dong Li

Frontiers in Neurology

doi 10.3389/fneur.2025.1643957

2,215 views

Original Research

Published on 02 Oct 2025

Association of hemorrhoidal disease with dementia risk: a nationwide cohort study

in Dementia and Neurodegenerative Diseases

Ho Geol Woo
Moo-Seok Park
Ju-Young Park
Hyejin Chun
Tae-Jin Song

Frontiers in Neurology

doi 10.3389/fneur.2025.1655944

11,259 views

Editorial

Published on 01 Oct 2025

Editorial: Neuropsychiatric symptoms and cognitive impairment

in Dementia and Neurodegenerative Diseases

Ioannis Liampas
Efthimios Dardiotis
Vasileios Siokas
Robert Fleischmann

Frontiers in Neurology

doi 10.3389/fneur.2025.1680162

2,651 views

Original Research

Published on 17 Sep 2025

Neuroanatomical changes in early Parkinson’s disease with mild cognitive impairment: gray matter and white matter damage

in Dementia and Neurodegenerative Diseases

Yaping Niu
Changlian Tan
Qin Shen
Sainan Cai
Qinru Liu
Min Wang
Congli Huang
Yiran Lin
Sinan Deng
Haiyan Liao

Frontiers in Neurology

doi 10.3389/fneur.2025.1641820

1,977 views

Systematic Review

Published on 15 Sep 2025

Efficacy and safety of traditional Chinese medicine and Western medicine in Alzheimer’s disease: a systematic review and meta-analysis

in Dementia and Neurodegenerative Diseases

Qi Wang
De-Long Wang
Xiu-Chu Zhang
Xin-Yu Jiang
Huan-Ning Jiang
Xue-Ying Yang
Te Zhang
Yu-Ying Lv
Quan Li

Frontiers in Neurology

doi 10.3389/fneur.2025.1607945

4,015 views

Clinical Trial

Published on 12 Sep 2025

Hekun decoction versus Femoston for women with amnestic mild cognitive impairment in early menopause: a randomized, three-arm, double-blind clinical trial

in Dementia and Neurodegenerative Diseases

Ziqi Zhai
Guangyao Lin
Siru Chen
Huicong Liu
Rui Yuan
Xianwei Gao
Xiaorong Ni
Mingjie Shen
Haiying Fan
Wenjun Wang

Frontiers in Neurology

doi 10.3389/fneur.2025.1610562

2,042 views

Original Research

Published on 12 Sep 2025

Navigating the diagnostic challenges of myoclonus in neurodegenerative disorders: video-EEG/polygraphy, clinical vignettes, and narrative analysis

in Dementia and Neurodegenerative Diseases

Giuseppe d’Orsi
Maria Teresa Di Claudio
Assunta Anna Soccio
Valentina Palumbo
Carmela Pia Ferro
Umberto Costantino
Raffaella Latino
Danilo Fogli

Frontiers in Neurology

doi 10.3389/fneur.2025.1655455

1,692 views

Original Research

Published on 11 Sep 2025

Development and validation of a predictive model for depression risk in patients with amyotrophic lateral sclerosis

in Dementia and Neurodegenerative Diseases

Man Liu
Tongyang Niu
Xinyi Zhang
Ziyao Zhang
Luqi Zhao
Jiaqi Li
Siyu Fu
Meiqi Han
Rui Li
Hui Dong

Frontiers in Neurology

doi 10.3389/fneur.2025.1639895

1,354 views

Systematic Review

Published on 10 Sep 2025

Association of vitamin D with risk of dementia: a dose-response meta-analysis of observational studies

in Dementia and Neurodegenerative Diseases

Yaping Huang
Yun Chen
Yan Wu
Yan Wu
Xinyi Dai
Juan Feng
Xia Li

Frontiers in Neurology

doi 10.3389/fneur.2025.1649841

4,442 views

Original Research

Published on 05 Sep 2025

Regional differences in the incidence of Alzheimer’s disease and related dementias in South Carolina

in Dementia and Neurodegenerative Diseases

Daniel A. Amoatika
Maggi C. Miller
Robert J. Adams
Nicholas J. Milano

Frontiers in Neurology

doi 10.3389/fneur.2025.1584127

1,847 views

Original Research

Published on 04 Sep 2025

Cognitive profile and frailty in patients with idiopathic normal pressure hydrocephalus

in Dementia and Neurodegenerative Diseases

Magnhild S. Dejgaard
Per Kristian Eide
Gro Gujord Tangen
Eva Skovlund
Geir Selbæk
Torgeir Bruun Wyller

Frontiers in Neurology

doi 10.3389/fneur.2025.1644507

1,677 views

Review

Published on 03 Sep 2025

Protein quality control systems in neurodegeneration – culprits, mitigators, and solutions?

in Dementia and Neurodegenerative Diseases

Aaron Ciechanover
Ido Livneh

Frontiers in Neurology

doi 10.3389/fneur.2025.1604076

11,980 views

Original Research

Published on 02 Sep 2025

Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia

in Dementia and Neurodegenerative Diseases

Yinghua Chen
Wei Sun
Zhongren Sun
Hongxu Zhao
Tong Wu
Yuanyu Song
Haoyu Wang
Ruiqi Qin
Xiaoqing Su
Junfeng Li

Frontiers in Neurology

doi 10.3389/fneur.2025.1629474

2,289 views

Systematic Review

Published on 29 Aug 2025

Evaluating the clinical evidence of TCM in Alzheimer’s disease: an evidence map perspective

in Dementia and Neurodegenerative Diseases

Shuqi Cui
Yongli Zhao
Xiaowen Wang
Yingzi Huang
Jiaxi Ye
Ziyong Deng
Yanjiang Li
Hui Qin
Li Wang
Yan Li

Frontiers in Neurology

doi 10.3389/fneur.2025.1571361

2,274 views

Original Research

Published on 26 Aug 2025

Nilotinib and imatinib: potential candidates for treatment of dementia and Parkinson’s disease through national health insurance data

in Dementia and Neurodegenerative Diseases

Jihun Song
Sun Jae Park
Yu-Jin Kim
Sang Min Park

Frontiers in Neurology

doi 10.3389/fneur.2025.1628876

2,174 views

Original Research

Accepted on 21 Aug 2025

Transcranial magnetic stimulation combined with virtual reality improves quality of life in patients with Parkinson's disease with depression

in Dementia and Neurodegenerative Diseases

Ruiping Gu
Guizhen Zeng

Frontiers in Neurology

668 views

Review

Published on 18 Aug 2025

Fluid biomarkers in familial frontotemporal dementia: progress and prospects

in Dementia and Neurodegenerative Diseases

Mengyao Guo
Linyuan Qin
Hanlin Cai
Ruihan Wang
Caimei Luo
Feng Yang
Shiyu Feng
Hui Gao
Qin Chen

Frontiers in Neurology

doi 10.3389/fneur.2025.1663609

2,951 views
1 citation

Mini Review

Published on 18 Aug 2025

Navigating challenges in hydrocephalus following intraventricular hemorrhage: a comprehensive review of current evidence

in Dementia and Neurodegenerative Diseases

Haozhou Wang
Xiaofeng Chen
Chao You
Ke Wu
Tong Sun

Frontiers in Neurology

doi 10.3389/fneur.2025.1630286

2,535 views

Original Research

Published on 15 Aug 2025

Efficacy of Ginkgo biloba extract in amyloid PET-positive patients with mild cognitive impairment

in Dementia and Neurodegenerative Diseases

YoungSoon Yang
Min-Seong Koo
Yong Tae Kwak

Frontiers in Neurology

doi 10.3389/fneur.2025.1639924

5,876 views
1 citation

Original Research

Published on 13 Aug 2025

Distinct cerebral cortical microstructural changes in idiopathic normal-pressure hydrocephalus

in Dementia and Neurodegenerative Diseases

Myong Hun Hahm
Shin Young Jeong
Suhyun Kim
Sang-Woo Lee
Ki-Su Park
Eunhee Park
Mi-Yeon Eun
Uicheul Yoon
Kyunghun Kang

Frontiers in Neurology

doi 10.3389/fneur.2025.1618788

1,401 views

757 articles

articles

The exploration of using plasma biomarkers of p-tau217 and p-tau181 for screening Alzheimer’s disease in very elderly people

Correction: Cognitive profile and frailty in patients with idiopathic normal pressure hydrocephalus

Adipose-derived mesenchymal stem cells for the treatment of Amyotrophic Lateral Sclerosis. A phase I/II safety and efficacy clinical trial

Review of the evidence on the influence of Wi-Fi 2.4 GHz radiation on oxidative stress and its possible relationship with Alzheimer’s disease

Effects of different physical activity interventions on executive function in older adults with dementia: a systematic review and network meta-analysis

Association of hemorrhoidal disease with dementia risk: a nationwide cohort study

Editorial: Neuropsychiatric symptoms and cognitive impairment

Neuroanatomical changes in early Parkinson’s disease with mild cognitive impairment: gray matter and white matter damage

Efficacy and safety of traditional Chinese medicine and Western medicine in Alzheimer’s disease: a systematic review and meta-analysis

Hekun decoction versus Femoston for women with amnestic mild cognitive impairment in early menopause: a randomized, three-arm, double-blind clinical trial

Navigating the diagnostic challenges of myoclonus in neurodegenerative disorders: video-EEG/polygraphy, clinical vignettes, and narrative analysis

Development and validation of a predictive model for depression risk in patients with amyotrophic lateral sclerosis

Association of vitamin D with risk of dementia: a dose-response meta-analysis of observational studies

Regional differences in the incidence of Alzheimer’s disease and related dementias in South Carolina

Cognitive profile and frailty in patients with idiopathic normal pressure hydrocephalus

Protein quality control systems in neurodegeneration – culprits, mitigators, and solutions?

Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia

Evaluating the clinical evidence of TCM in Alzheimer’s disease: an evidence map perspective

Nilotinib and imatinib: potential candidates for treatment of dementia and Parkinson’s disease through national health insurance data

Transcranial magnetic stimulation combined with virtual reality improves quality of life in patients with Parkinson's disease with depression

Fluid biomarkers in familial frontotemporal dementia: progress and prospects

Navigating challenges in hydrocephalus following intraventricular hemorrhage: a comprehensive review of current evidence

Efficacy of Ginkgo biloba extract in amyloid PET-positive patients with mild cognitive impairment

Distinct cerebral cortical microstructural changes in idiopathic normal-pressure hydrocephalus

articles

The exploration of using plasma biomarkers of p-tau217 and p-tau181 for screening Alzheimer’s disease in very elderly people

Correction: Cognitive profile and frailty in patients with idiopathic normal pressure hydrocephalus

Adipose-derived mesenchymal stem cells for the treatment of Amyotrophic Lateral Sclerosis. A phase I/II safety and efficacy clinical trial

Review of the evidence on the influence of Wi-Fi 2.4 GHz radiation on oxidative stress and its possible relationship with Alzheimer’s disease

Effects of different physical activity interventions on executive function in older adults with dementia: a systematic review and network meta-analysis

Association of hemorrhoidal disease with dementia risk: a nationwide cohort study

Editorial: Neuropsychiatric symptoms and cognitive impairment

Neuroanatomical changes in early Parkinson’s disease with mild cognitive impairment: gray matter and white matter damage

Efficacy and safety of traditional Chinese medicine and Western medicine in Alzheimer’s disease: a systematic review and meta-analysis

Hekun decoction versus Femoston for women with amnestic mild cognitive impairment in early menopause: a randomized, three-arm, double-blind clinical trial

Navigating the diagnostic challenges of myoclonus in neurodegenerative disorders: video-EEG/polygraphy, clinical vignettes, and narrative analysis

Development and validation of a predictive model for depression risk in patients with amyotrophic lateral sclerosis

Association of vitamin D with risk of dementia: a dose-response meta-analysis of observational studies

Regional differences in the incidence of Alzheimer’s disease and related dementias in South Carolina

Cognitive profile and frailty in patients with idiopathic normal pressure hydrocephalus

Protein quality control systems in neurodegeneration – culprits, mitigators, and solutions?

Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia

Evaluating the clinical evidence of TCM in Alzheimer’s disease: an evidence map perspective

Nilotinib and imatinib: potential candidates for treatment of dementia and Parkinson’s disease through national health insurance data

Transcranial magnetic stimulation combined with virtual reality improves quality of life in patients with Parkinson's disease with depression

Fluid biomarkers in familial frontotemporal dementia: progress and prospects

Navigating challenges in hydrocephalus following intraventricular hemorrhage: a comprehensive review of current evidence

Efficacy of Ginkgo biloba extract in amyloid PET-positive patients with mild cognitive impairment

Distinct cerebral cortical microstructural changes in idiopathic normal-pressure hydrocephalus

Review of the evidence on the influence of Wi-Fi 2.4 GHz radiation on oxidative stress and its possible relationship with Alzheimer’s disease