Frontiers in Neuroscience | Neurodegeneration

Clinical Trial

Published on 16 Apr 2025

16 weeks of moderate intensity resistance exercise improves strength but is insufficient to alter brain structure in Gulf War Veterans with chronic musculoskeletal pain: a randomized controlled trial

in Neurodegeneration

Stephanie M. Van Riper
Jacob V. Ninneman
Aaron J. Stegner
Brady A. Riedner
Laura D. Ellingson
Ryan J. Dougherty
Patrick J. O’Connor
Gunnar A. Roberge
Andrew L. Alexander
Doug C. Dean

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1488397

301 views

Review

Accepted on 15 Apr 2025

Comparative Analysis of Neuroinflammatory Pathways in Alzheimer's Disease, Parkinson's Disease, and Multiple Sclerosis: Insights into Similarities and Distinctions

in Neurodegeneration

Julia Doroszkiewicz
Izabela Winkel
Barbara Mroczko

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1579511

Original Research

Accepted on 14 Apr 2025

Sweet Spot Mapping and Structural Connectivity in Subthalamic Stimulation: Predicting Neuropsychiatric Outcomes in Parkinson's Disease

in Neurodegeneration

Jiuqi Yan
Jian Sun
Xiang Wei
Chang Qiu
Liang Zhao
Bei Luo
Wenwen Dong
Jingxuan Liu
Guanghan Lu
Wenbin Zhang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1577588

126 views

Original Research

Accepted on 11 Apr 2025

Peak alpha Frequency and alpha Power Spectral Density as Vulnerability Markers of Cognitive Impairment in Parkinson's Disease: An Exploratory EEG Study

in Neurodegeneration

Yuqing Zhao
Jiayu Cai
Jian Song
Aoran Hi
Weicheng Kong
Xinlei Li
Min Xia
Wei Wei
Xiehua Xue

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1575815

157 views

Review

Accepted on 10 Apr 2025

Significance of gene therapy in neurodegenerative diseases

in Neurodegeneration

Lingling Wang
Lin Ma
Zihan Gao
Ying Wang
Jiaoxue Qiu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1515255

255 views

Editorial

Published on 10 Apr 2025

Editorial: Translational research in hereditary spastic paraplegias: filling the diagnosis gap and therapeutic perspectives

in Neurodegeneration

Andrea Martinuzzi
Craig Blackstone
Giovanni Stevanin

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1595717

370 views

Review

Accepted on 08 Apr 2025

Role and mechanism of molecular hydrogen in the treatment of Parkinson's diseases

in Neurodegeneration

Fengjiao Wang
Guangjie Zhang
Qingfeng Zhai

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1576773

Original Research

Accepted on 08 Apr 2025

NFκB1: A Common Biomarker Linking Alzheimer's and Parkinson's Disease Pathology

in Neurodegeneration

Adam Cunningham
Emma Barrett
Sebastian Risch
Peter Lee
Chan Lee
Abhay Moghekar
Prabir Patra
Joon W Shim

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1589857

191 views

Review

Published on 08 Apr 2025

The interplay between α-synuclein aggregation and necroptosis in Parkinson’s disease: a spatiotemporal perspective

in Neurodegeneration

Haoran Xiang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1567445

551 views

Original Research

Published on 01 Apr 2025

Intrastriatal injection of alpha-synuclein preformed fibrils to rats results in L-DOPA reversible sensorimotor impairments and alterations in non-motor function

in Neurodegeneration

Sheila M. Fleming
Sophia Scott
Edward J. Hamad
Danielle E. Herman
John G. Holden
Lily Yan
Katrina Linning-Duffy
Christopher J. Kemp
Joseph R. Patterson
Kathryn M. Miller

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1556447

616 views

Review

Published on 27 Mar 2025

α-synuclein and tau: interactions, cross-seeding, and the redefinition of synucleinopathies as complex proteinopathies

in Neurodegeneration

Francisco J. Padilla-Godínez
Eunice Ruth Vázquez-García
María Isabel Trujillo-Villagrán
Luis O. Soto-Rojas
Marcela Palomero-Rivero
Omar Hernández-González
Francisco Pérez-Eugenio
Omar Collazo-Navarrete
Oscar Arias-Carrión
Magdalena Guerra-Crespo

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1570553

921 views

Original Research

Published on 25 Mar 2025

Association between serum sodium and sporadic Parkinson’s disease

in Neurodegeneration

Wen Zhou
Qingqing Xia
Duan Liu
Jun-ying Li
Liang Gong

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1555831

563 views

Editorial

Published on 18 Mar 2025

Editorial: Innovative approaches to catalyze preclinical and clinical research on amyotrophic lateral sclerosis (ALS) and related disorders

in Neurodegeneration

Thibaut Burg
Laura Tzeplaeff
Raphaelle Cassel
Paul Lingor

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1582539

980 views

Perspective

Published on 17 Mar 2025

High efficacy therapy to prevent the formation of meningeal tertiary lymphoid organs after CXCL13 index screening in early multiple sclerosis

in Neurodegeneration

Ana C. Londoño
Carlos A. Mora

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1558810

443 views

Review

Accepted on 14 Mar 2025

VPS13 and bridge-like lipid transporters, mechanisms and mysteries.

in Neurodegeneration

Laura Elizabeth Swan

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1534061

243 views

Original Research

Published on 13 Mar 2025

Differential cognitive functioning in the digital clock drawing test in AD-MCI and PD-MCI populations

in Neurodegeneration

Chen Wang
Kai Li
Shouqiang Huang
Jiakang Liu
Shuwu Li
Yuting Tu
Bo Wang
Pengpeng Zhang
Yuntian Luo
Tong Chen

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1558448

790 views