Frontiers in Neuroscience | Neurodegeneration

Original Research

Published on 30 Sep 2021

Computational Interspecies Translation Between Alzheimer’s Disease Mouse Models and Human Subjects Identifies Innate Immune Complement, TYROBP, and TAM Receptor Agonist Signatures, Distinct From Influences of Aging

in Neurodegeneration

Meelim J. Lee
Chuangqi Wang
Molly J. Carroll
Douglas K. Brubaker
Bradley T. Hyman
Douglas A. Lauffenburger

Frontiers in Neuroscience

doi 10.3389/fnins.2021.727784

7,513 views
25 citations

Original Research

Published on 27 Sep 2021

Electroacupuncture Improves M2 Microglia Polarization and Glia Anti-inflammation of Hippocampus in Alzheimer’s Disease

in Neurodegeneration

Lushuang Xie
Yi Liu
Ning Zhang
Chenyu Li
Aaron F. Sandhu
George Williams
Yan Shen
Hongying Li
Qiaofeng Wu
Shuguang Yu

Frontiers in Neuroscience

doi 10.3389/fnins.2021.689629

17,286 views
97 citations

Review

Published on 27 Sep 2021

Neurofilament Proteins as Biomarkers to Monitor Neurological Diseases and the Efficacy of Therapies

in Neurodegeneration

Aidong Yuan
Ralph A. Nixon

Frontiers in Neuroscience

doi 10.3389/fnins.2021.689938

42,176 views
264 citations

Hypothesis and Theory

Published on 24 Sep 2021

A Multifaceted Approach to Optimizing AAV Delivery to the Brain for the Treatment of Neurodegenerative Diseases

in Neurodegeneration

Jonathan M. Fischell
Paul S. Fishman

Frontiers in Neuroscience

doi 10.3389/fnins.2021.747726

24,112 views
58 citations

Review

Published on 24 Sep 2021

Microglia in Neuroinflammation and Neurodegeneration: From Understanding to Therapy

in Neurodegeneration

Luca Muzio
Alice Viotti
Gianvito Martino

Frontiers in Neuroscience

doi 10.3389/fnins.2021.742065

66,090 views
499 citations

Original Research

Published on 24 Sep 2021

hnRNP A1B, a Splice Variant of HNRNPA1, Is Spatially and Temporally Regulated

in Neurodegeneration

Myriam Gagné
Jade-Emmanuelle Deshaies
Hadjara Sidibé
Yousri Benchaar
Danielle Arbour
Alicia Dubinski
Gurleen Litt
Sarah Peyrard
Richard Robitaille
Chantelle F. Sephton

Frontiers in Neuroscience

doi 10.3389/fnins.2021.724307

6,043 views
8 citations

Correction

Published on 23 Sep 2021

Corrigendum: Neuronal–Glial Interaction in a Triple-Transgenic Mouse Model of Alzheimer's Disease: Gene Ontology and Lithium Pathways

in Neurodegeneration

Nicole Kemberly R. Rocha
Rafael Themoteo
Helena Brentani
Orestes V. Forlenza
Vanessa De Jesus Rodrigues De Paula

Frontiers in Neuroscience

doi 10.3389/fnins.2021.726983

1,828 views
1 citation

Review

Published on 22 Sep 2021

Retinal Vasculopathy in Alzheimer’s Disease

in Neurodegeneration

Haoshen Shi
Yosef Koronyo
Altan Rentsendorj
Dieu-Trang Fuchs
Julia Sheyn
Keith L. Black
Nazanin Mirzaei
Maya Koronyo-Hamaoui

Frontiers in Neuroscience

doi 10.3389/fnins.2021.731614

19,112 views
71 citations

Original Research

Published on 21 Sep 2021

Astrocytic and Neuronal Apolipoprotein E Isoforms Differentially Affect Neuronal Excitability

in Neurodegeneration

Sabine C. Konings
Laura Torres-Garcia
Isak Martinsson
Gunnar K. Gouras

Frontiers in Neuroscience

doi 10.3389/fnins.2021.734001

12,777 views
40 citations

Review

Published on 20 Sep 2021

Cholinergic Receptor Modulation as a Target for Preventing Dementia in Parkinson’s Disease

in Neurodegeneration

Alexandre Iarkov
Cristhian Mendoza
Valentina Echeverria

Frontiers in Neuroscience

doi 10.3389/fnins.2021.665820

13,610 views
25 citations

Case Report

Published on 17 Sep 2021

Case Report: Coexistence of Alzheimer-Type Neuropathology in Fragile X-Associated Tremor Ataxia Syndrome

in Neurodegeneration

Maria Jimena Salcedo-Arellano
Desiree Sanchez
Jun Yi Wang
Yingratana A. McLennan
Courtney Jessica Clark
Pablo Juarez
Andrea Schneider
Flora Tassone
Randi J. Hagerman
Verónica Martínez-Cerdeño

Frontiers in Neuroscience

doi 10.3389/fnins.2021.720253

5,201 views
11 citations

Review

Published on 17 Sep 2021

Multiple Sclerosis and the Endogenous Opioid System

in Neurodegeneration

Zoë Dworsky-Fried
Caylin I. Chadwick
Bradley J. Kerr
Anna M. W. Taylor

Frontiers in Neuroscience

doi 10.3389/fnins.2021.741503

17,938 views
14 citations

Review

Published on 14 Sep 2021

Green Tea Polyphenol Epigallocatechin-Gallate in Amyloid Aggregation and Neurodegenerative Diseases

in Neurodegeneration

Luiza Fernandes
Thyago R. Cardim-Pires
Debora Foguel
Fernando L. Palhano

Frontiers in Neuroscience

doi 10.3389/fnins.2021.718188

18,570 views
94 citations

Original Research

Published on 13 Sep 2021

Fixel-Based Analysis Effectively Identifies White Matter Tract Degeneration in Huntington’s Disease

in Neurodegeneration

Sher Li Oh
Chiung-Mei Chen
Yih-Ru Wu
Maria Valdes Hernandez
Chih-Chien Tsai
Jur-Shan Cheng
Yao-Liang Chen
Yi-Ming Wu
Yu-Chun Lin
Jiun-Jie Wang

Frontiers in Neuroscience

doi 10.3389/fnins.2021.711651

6,174 views
15 citations

Original Research

Published on 10 Sep 2021

Serum Cystatin C as a Potential Predictor of the Severity of Multiple System Atrophy With Predominant Cerebellar Ataxia: A Case-Control Study in Chinese Population

in Neurodegeneration

Fei Ye
Tianzhu Wang
Huan Li
Jie Liang
Xiaoxin Wu
Wenli Sheng

Frontiers in Neuroscience

doi 10.3389/fnins.2021.663980

3,136 views
5 citations

Original Research

Published on 09 Sep 2021

Cerebrospinal Fluid MicroRNA Changes in Cognitively Normal Veterans With a History of Deployment-Associated Mild Traumatic Brain Injury

in Neurodegeneration

Theresa A. Lusardi
Ursula S. Sandau
Nikita A. Sakhanenko
Sarah Catherine B. Baker
Jack T. Wiedrick
Jodi A. Lapidus
Murray A. Raskind
Ge Li
Elaine R. Peskind
David J. Galas

Frontiers in Neuroscience

doi 10.3389/fnins.2021.720778

5,195 views
11 citations

Review

Published on 09 Sep 2021

Nerve Growth Factor-Based Therapy in Alzheimer’s Disease and Age-Related Macular Degeneration

in Neurodegeneration

Giuseppina Amadoro
Valentina Latina
Bijorn Omar Balzamino
Rosanna Squitti
Monica Varano
Pietro Calissano
Alessandra Micera

Frontiers in Neuroscience

doi 10.3389/fnins.2021.735928

14,042 views
38 citations

Editorial

Published on 09 Sep 2021

Editorial: Infection, Inflammation, Cardiovascular Diseases, and Neurodegeneration

in Neurodegeneration

Deng-Feng Zhang
Xian-Le Bu
Gjumrakch Aliev
Feiqi Zhu

Frontiers in Neuroscience

doi 10.3389/fnins.2021.750172

2,175 views
1 citation

Original Research

Published on 07 Sep 2021

Characterizing the Retinal Phenotype of the Thy1-h[A30P]α-syn Mouse Model of Parkinson’s Disease

in Neurodegeneration

Lien Veys
Joyce Devroye
Evy Lefevere
Lien Cools
Marjan Vandenabeele
Lies De Groef

Frontiers in Neuroscience

doi 10.3389/fnins.2021.726476

5,911 views
15 citations

Original Research

Published on 07 Sep 2021

Predicting Motor Outcome of Subthalamic Nucleus Deep Brain Stimulation for Parkinson’s Disease Using Quantitative Susceptibility Mapping and Radiomics: A Pilot Study

in Neurodegeneration

Yu Liu
Bin Xiao
Chencheng Zhang
Junchen Li
Yijie Lai
Feng Shi
Dinggang Shen
Linbin Wang
Bomin Sun
Yan Li

Frontiers in Neuroscience

doi 10.3389/fnins.2021.731109

10,251 views
23 citations

Original Research

Published on 03 Sep 2021

Neurofilament Light Chain and Intermediate HTT Alleles as Combined Biomarkers in Italian ALS Patients

in Neurodegeneration

Assunta Ingannato
Silvia Bagnoli
Salvatore Mazzeo
Valentina Bessi
Sabrina Matà
Monica Del Mastio
Gemma Lombardi
Camilla Ferrari
Sandro Sorbi
Benedetta Nacmias

Frontiers in Neuroscience

doi 10.3389/fnins.2021.695049

2,979 views
5 citations

Mini Review

Published on 01 Sep 2021

Contribution of RNA/DNA Binding Protein Dysfunction in Oligodendrocytes in the Pathogenesis of the Amyotrophic Lateral Sclerosis/Frontotemporal Lobar Degeneration Spectrum Diseases

in Neurodegeneration

Chiara F. Valori
Manuela Neumann

Frontiers in Neuroscience

doi 10.3389/fnins.2021.724891

5,047 views
9 citations

Review

Published on 01 Sep 2021

Amyloid-β and α-Synuclein Immunotherapy: From Experimental Studies to Clinical Trials

in Neurodegeneration

Jacqui Taryn Nimmo
Louise Kelly
Ajay Verma
Roxana O. Carare
James A. R. Nicoll
Jean-Cosme Dodart

Frontiers in Neuroscience

doi 10.3389/fnins.2021.733857

19,381 views
40 citations

Brief Research Report

Published on 01 Sep 2021

Dysregulation in Subcellular Localization of Myelin Basic Protein mRNA Does Not Result in Altered Myelination in Amyotrophic Lateral Sclerosis

in Neurodegeneration

Samantha K. Barton
Jenna M. Gregory
Bhuvaneish T. Selvaraj
Karina McDade
Christopher M. Henstridge
Tara L. Spires-Jones
Owen G. James
Arpan R. Mehta
David Story
Karen Burr

Frontiers in Neuroscience

doi 10.3389/fnins.2021.705306

5,772 views
7 citations

2,276 articles

articles

Computational Interspecies Translation Between Alzheimer’s Disease Mouse Models and Human Subjects Identifies Innate Immune Complement, TYROBP, and TAM Receptor Agonist Signatures, Distinct From Influences of Aging

Electroacupuncture Improves M2 Microglia Polarization and Glia Anti-inflammation of Hippocampus in Alzheimer’s Disease

Neurofilament Proteins as Biomarkers to Monitor Neurological Diseases and the Efficacy of Therapies

A Multifaceted Approach to Optimizing AAV Delivery to the Brain for the Treatment of Neurodegenerative Diseases

Microglia in Neuroinflammation and Neurodegeneration: From Understanding to Therapy

hnRNP A1B, a Splice Variant of HNRNPA1, Is Spatially and Temporally Regulated

Corrigendum: Neuronal–Glial Interaction in a Triple-Transgenic Mouse Model of Alzheimer's Disease: Gene Ontology and Lithium Pathways

Retinal Vasculopathy in Alzheimer’s Disease

Astrocytic and Neuronal Apolipoprotein E Isoforms Differentially Affect Neuronal Excitability

Cholinergic Receptor Modulation as a Target for Preventing Dementia in Parkinson’s Disease

Case Report: Coexistence of Alzheimer-Type Neuropathology in Fragile X-Associated Tremor Ataxia Syndrome

Multiple Sclerosis and the Endogenous Opioid System

Green Tea Polyphenol Epigallocatechin-Gallate in Amyloid Aggregation and Neurodegenerative Diseases

Fixel-Based Analysis Effectively Identifies White Matter Tract Degeneration in Huntington’s Disease

Serum Cystatin C as a Potential Predictor of the Severity of Multiple System Atrophy With Predominant Cerebellar Ataxia: A Case-Control Study in Chinese Population

Cerebrospinal Fluid MicroRNA Changes in Cognitively Normal Veterans With a History of Deployment-Associated Mild Traumatic Brain Injury

Nerve Growth Factor-Based Therapy in Alzheimer’s Disease and Age-Related Macular Degeneration

Editorial: Infection, Inflammation, Cardiovascular Diseases, and Neurodegeneration

Characterizing the Retinal Phenotype of the Thy1-h[A30P]α-syn Mouse Model of Parkinson’s Disease

Predicting Motor Outcome of Subthalamic Nucleus Deep Brain Stimulation for Parkinson’s Disease Using Quantitative Susceptibility Mapping and Radiomics: A Pilot Study

Neurofilament Light Chain and Intermediate HTT Alleles as Combined Biomarkers in Italian ALS Patients

Contribution of RNA/DNA Binding Protein Dysfunction in Oligodendrocytes in the Pathogenesis of the Amyotrophic Lateral Sclerosis/Frontotemporal Lobar Degeneration Spectrum Diseases

Amyloid-β and α-Synuclein Immunotherapy: From Experimental Studies to Clinical Trials

Dysregulation in Subcellular Localization of Myelin Basic Protein mRNA Does Not Result in Altered Myelination in Amyotrophic Lateral Sclerosis