Frontiers in Neuroscience | Neurodegeneration

Original Research

Published on 13 Mar 2025

Differential cognitive functioning in the digital clock drawing test in AD-MCI and PD-MCI populations

in Neurodegeneration

Chen Wang
Kai Li
Shouqiang Huang
Jiakang Liu
Shuwu Li
Yuting Tu
Bo Wang
Pengpeng Zhang
Yuntian Luo
Tong Chen

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1558448

3,049 views
4 citations

Review

Published on 12 Mar 2025

The role of intracellular and extracellular copper compartmentalization in Alzheimer’s disease pathology and its implications for diagnosis and therapy

in Neurodegeneration

Yu-Qi Li
Shuang-Shuang Tan
Di Wu
Qian Zhang
Tao Wang
Gang Zheng

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1553064

3,176 views
5 citations

Original Research

Published on 12 Mar 2025

Phosphorylated neurofilament heavy chain (pNfH) concentration in cerebrospinal fluid predicts overall disease aggressiveness (D50) in amyotrophic lateral sclerosis

in Neurodegeneration

Julia Meyer
Nayana Gaur
Janina von der Gablentz
Bernd Friedrich
Annekathrin Roediger
Julian Grosskreutz
Robert Steinbach

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1536818

2,486 views
2 citations

Original Research

Published on 12 Mar 2025

Distinct brain activity patterns associated with traditional Chinese medicine syndromes: a task-fMRI study of mild cognitive impairment

in Neurodegeneration

Zhaoying Li
Shanyu Liu
Yuling Shen
Huan Zhao
Zhenwei Chen
Rui Tan
Zhuoling Li
Ling Quan
Dongdong Yang
Min Shi

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1555365

2,071 views

Original Research

Published on 05 Mar 2025

The systemic inflammation markers as potential predictors of disease progression and survival time in amyotrophic lateral sclerosis

in Neurodegeneration

Ye Hong
Jian-Quan Shi
Shuai Feng
Shi-Qi Huang
Zhen-Hua Yuan
Shen Liu
Xiao-Hao Zhang
Jun-Shan Zhou
Teng Jiang
Hong-Dong Zhao

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1552949

2,715 views
1 citation

Original Research

Published on 05 Mar 2025

Oxidative stress and inflammation combine to exacerbate cochlear damage and sensorineural hearing loss in C57BL/6 mice

in Neurodegeneration

Zhongwu Su
Yuyan Chen
Yu Liu
Jinyuan Cao
Jie Cui
Haitong Chen
Qi Li

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1563428

2,807 views
2 citations

Original Research

Published on 28 Feb 2025

Mutation in Wdr45 leads to early motor dysfunction and widespread aberrant axon terminals in a beta-propeller protein associated neurodegeneration (BPAN) patient-inspired mouse model

in Neurodegeneration

Brandon L. Meyerink
Krishna S. Karia
Mitchell J. Rechtzigel
Prithvi R. Patthi
Ariana C. Edwards
Jessica M. Howard
Elizabeth R. Aaseng
Shamiq Aftab
Jill M. Weimer
Louis-Jan Pilaz

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1545004

4,861 views
2 citations

Review

Published on 28 Feb 2025

Physical activity and neuroplasticity in neurodegenerative disorders: a comprehensive review of exercise interventions, cognitive training, and AI applications

in Neurodegeneration

Lamia Ben Ezzdine
Wissem Dhahbi
Ismail Dergaa
Halil İbrahim Ceylan
Noomen Guelmami
Helmi Ben Saad
Karim Chamari
Valentina Stefanica
Abdelfatteh El Omri

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1502417

22,299 views
29 citations

Original Research

Published on 27 Feb 2025

Assessment of the impact of reconstitution therapies—cladribine tablets and alemtuzumab—on the atrophy progression among patients with relapse-remitting multiple sclerosis

in Neurodegeneration

Aleksandra Pogoda-Wesołowska
Ignacy Stachura
Arkadiusz Zegadło
Marzena Maciągowska-Terela
Karolina Sobolewska
Aleksander Dębiec
Jacek Staszewski
Adam Stępień

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1531163

2,041 views
1 citation

Original Research

Published on 26 Feb 2025

Persistent homology for MCI classification: a comparative analysis between graph and Vietoris-Rips filtrations

in Neurodegeneration

Debanjali Bhattacharya
Rajneet Kaur
Ninad Aithal
Neelam Sinha
Thomas Gregor Issac

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1518984

3,161 views
7 citations

Systematic Review

Published on 25 Feb 2025

Bibliometric analysis of cognitive dysfunction after traumatic brain injury

in Neurodegeneration

Jihua Hu
Ruiting Zhu
Xin Zhang
Yuchen Zhang
Jixin Liu
Wenyang Wang
Chiyin Li
Tong Yang
Ming Zhang
Xuan Niu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1534735

3,427 views
1 citation

Review

Published on 20 Feb 2025

The role of Apolipoprotein E4 on cognitive impairment in Parkinson’s disease and Parkinsonisms

in Neurodegeneration

Angenelle Eve Rosal
Sarah L. Martin
Antonio P. Strafella

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1515374

3,761 views
5 citations

Review

Published on 14 Feb 2025

Application of artificial intelligence in Alzheimer’s disease: a bibliometric analysis

in Neurodegeneration

Sijia Song
Tong Li
Wei Lin
Ran Liu
Yujie Zhang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1511350

7,242 views
6 citations

Editorial

Published on 14 Feb 2025

Editorial: Neuroinflammation and neurodegenerative diseases

in Neurodegeneration

Pradeep Kumar
Kiran Bhaskar

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1561636

2,092 views
2 citations

Review

Published on 12 Feb 2025

TDP-43 as a potential retinal biomarker for neurodegenerative diseases

in Neurodegeneration

Margit Glashutter
Printha Wijesinghe
Joanne A. Matsubara

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1533045

6,136 views
5 citations

Original Research

Published on 07 Feb 2025

Relationship between regional relative theta power and amyloid deposition in mild cognitive impairment: an exploratory study

in Neurodegeneration

Jaesub Park
Woo Jung Kim
Han Wool Jung
Jae-Jin Kim
Jin Young Park

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1510878

2,138 views
2 citations

Original Research

Published on 04 Feb 2025

A bibliometric analysis of research on dementia comorbid with depression from 2005 to 2024

in Neurodegeneration

Xia Li
Wei Su
Lili Cai

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1508662

3,960 views
3 citations

Review

Published on 04 Feb 2025

Hyperthermia and targeting heat shock proteins: innovative approaches for neurodegenerative disorders and Long COVID

in Neurodegeneration

David M. Smadja
M. Marc Abreu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1475376

5,841 views
6 citations

Editorial

Published on 29 Jan 2025

Editorial: Molecular and cellular pathways leading to mitochondrial dysfunction and neurodegeneration: lessons from in vivo models, volume II

in Neurodegeneration

Shabab B. Hannan
Federica De Lazzari
Aurora Gomez-Duran
Juan A. Navarro
Gloria Brea-Calvo
Alvaro Sanchez-Martinez

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1557013

1,939 views

Editorial

Published on 29 Jan 2025

Editorial: Neurodegeneration and cognitive impairment after traumatic brain injury

in Neurodegeneration

Tao Liu
Li Ma
Yu Chen
Rongcai Jiang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1552527

2,469 views
1 citation

Original Research

Published on 28 Jan 2025

Altered brain functional network connectivity and topology in type 2 diabetes mellitus

in Neurodegeneration

Weiwei Ni
Weiyin Vivian Liu
Mingrui Li
Shouchao Wei
Xuanzi Xu
Shutong Huang
Lanhui Zhu
Jieru Wang
Fengling Wen
Hailing Zhou

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1472010

2,993 views
3 citations

Brief Research Report

Published on 27 Jan 2025

RIPK1 expression and inhibition in tauopathies: implications for neuroinflammation and neuroprotection

in Neurodegeneration

Ignacio Silva-Llanes
Enrique Madruga
Ana Martínez
Isabel Lastres-Becker

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1530809

3,141 views
2 citations

Original Research

Published on 17 Jan 2025

Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS

in Neurodegeneration

Adam Eckardt
Charles Marble
Bradley Fern
Henry Moritz
Charles Kotula
Jiayi Ke
Clarisse Rebancos
Samantha Robertson
Hiroshi Nishimune
Masatoshi Suzuki

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1527181

3,161 views
2 citations

Brief Research Report

Published on 17 Jan 2025

Impairment of neuronal activity in the dorsolateral prefrontal cortex occurs early in parkinsonism

in Neurodegeneration

Noah Hjelle
Biswaranjan Mohanty
Tanner Hubbard
Matthew D. Johnson
Jing Wang
Luke A. Johnson
Jerrold L. Vitek

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1521443

2,087 views
5 citations

2,250 articles

articles

Differential cognitive functioning in the digital clock drawing test in AD-MCI and PD-MCI populations

The role of intracellular and extracellular copper compartmentalization in Alzheimer’s disease pathology and its implications for diagnosis and therapy

Phosphorylated neurofilament heavy chain (pNfH) concentration in cerebrospinal fluid predicts overall disease aggressiveness (D50) in amyotrophic lateral sclerosis

Distinct brain activity patterns associated with traditional Chinese medicine syndromes: a task-fMRI study of mild cognitive impairment

The systemic inflammation markers as potential predictors of disease progression and survival time in amyotrophic lateral sclerosis

Oxidative stress and inflammation combine to exacerbate cochlear damage and sensorineural hearing loss in C57BL/6 mice

Mutation in Wdr45 leads to early motor dysfunction and widespread aberrant axon terminals in a beta-propeller protein associated neurodegeneration (BPAN) patient-inspired mouse model

Physical activity and neuroplasticity in neurodegenerative disorders: a comprehensive review of exercise interventions, cognitive training, and AI applications

Assessment of the impact of reconstitution therapies—cladribine tablets and alemtuzumab—on the atrophy progression among patients with relapse-remitting multiple sclerosis

Persistent homology for MCI classification: a comparative analysis between graph and Vietoris-Rips filtrations

Bibliometric analysis of cognitive dysfunction after traumatic brain injury

The role of Apolipoprotein E4 on cognitive impairment in Parkinson’s disease and Parkinsonisms

Application of artificial intelligence in Alzheimer’s disease: a bibliometric analysis

Editorial: Neuroinflammation and neurodegenerative diseases

TDP-43 as a potential retinal biomarker for neurodegenerative diseases

Relationship between regional relative theta power and amyloid deposition in mild cognitive impairment: an exploratory study

A bibliometric analysis of research on dementia comorbid with depression from 2005 to 2024

Hyperthermia and targeting heat shock proteins: innovative approaches for neurodegenerative disorders and Long COVID

Editorial: Molecular and cellular pathways leading to mitochondrial dysfunction and neurodegeneration: lessons from in vivo models, volume II

Editorial: Neurodegeneration and cognitive impairment after traumatic brain injury

Altered brain functional network connectivity and topology in type 2 diabetes mellitus

RIPK1 expression and inhibition in tauopathies: implications for neuroinflammation and neuroprotection

Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS

Impairment of neuronal activity in the dorsolateral prefrontal cortex occurs early in parkinsonism