Frontiers in Neuroscience | Neuropharmacology

Original Research

Published on 31 Jan 2014

The hypocretin/orexin antagonist almorexant promotes sleep without impairment of performance in rats

in Neuropharmacology

Stephen R Morairty
Alan James Wilk
Webster U. Lincoln
Thomas C Neylan
Thomas S Kilduff

Frontiers in Neuroscience

doi 10.3389/fnins.2014.00003

10,824 views
37 citations

Original Research

Published on 31 Jan 2014

Characterization of early cortical population response to thalamocortical input in vitro

in Neuropharmacology

Michael Raymond Heliodor Hill
Susan Adel Greenfield

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00273

7,064 views
5 citations

Original Research

Published on 31 Jan 2014

Effects of a newly developed potent orexin-2 receptor-selective antagonist, compound 1 m, on sleep/wakefulness states in mice

in Neuropharmacology

Keishi Etori
Yuki Saito
Natsuko Tsujino
Takeshi Sakurai

Frontiers in Neuroscience

doi 10.3389/fnins.2014.00008

14,518 views
57 citations

Original Research

Published on 28 Jan 2014

LSN2424100: a novel, potent orexin-2 receptor antagonist with selectivity over orexin-1 receptors and activity in an animal model predictive of antidepressant-like efficacy

in Neuropharmacology

Thomas Edward Fitch
Mark J Benvenga
Cynthia D Jesudason
Charity Zink
Amy B Vandergriff
Michelle Menezes
Douglas A Schober
Linda M Rorick-Kehn

Frontiers in Neuroscience

doi 10.3389/fnins.2014.00005

8,900 views
32 citations

Mini Review

Published on 30 Dec 2013

Orexin, orexin receptor antagonists and central cardiovascular control

in Neuropharmacology

Pascal Carrive

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00257

13,511 views
57 citations

Original Research

Published on 24 Dec 2013

Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulators

in Neuropharmacology

Andres D. Ramirez
Anthony L. Gotter
Steven V. Fox
Pamela L. Tannenbaum
Lihang Yao
Spencer J. Tye
Terrence McDonald
Joseph Brunner
Susan L. Garson
Duane R. Reiss

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00254

12,053 views
37 citations

Original Research

Published on 20 Dec 2013

Differential actions of orexin receptors in brainstem cholinergic and monoaminergic neurons revealed by receptor knockouts: implications for orexinergic signaling in arousal and narcolepsy

in Neuropharmacology

Kristi A Kohlmeier
Christopher J Tyler
Mike Kalogiannis
Masaru Ishibashi
Morten P Kristensen
Iryna Gumenchuk
Richard M Chemelli
Yaz Kisanuki
Masashi Yanagisawa
Christopher S Leonard

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00246

8,610 views
46 citations

Review

Published on 20 Dec 2013

Cannabinoid-hypocretin cross-talk in the central nervous system: what we know so far

in Neuropharmacology

África Flores
Rafael Maldonado
Fernando Berrendero

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00256

26,589 views
61 citations

Original Research

Published on 17 Dec 2013

Dynorphin B induces lateral asymmetric changes in feline spinal cord reflexes

in Neuropharmacology

Inna Vereshchaka
Alexander Kostyukov

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00244

3,525 views
3 citations

Mini Review

Published on 17 Dec 2013

Is memantine a potential therapeutic for Rett syndrome?

in Neuropharmacology

Olivia Bello
Kelsey Blair
Christopher Chapleau
Jennifer Larimore

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00245

7,448 views
6 citations

Original Research

Published on 10 Dec 2013

Distinct effects of IPSU and suvorexant on mouse sleep architecture

in Neuropharmacology

Daniel Hoyer
Thomas Dürst
Markus Fendt
Laura H Jacobson
Claudia Betschart
Samuel Hintermann
Dirk Behnke
Simona Cotesta
Grit Laue
Silvio Ofner

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00235

10,871 views
38 citations

Original Research

Published on 03 Dec 2013

Kinetic properties of “dual” orexin receptor antagonists at OX1R and OX2R orexin receptors

in Neuropharmacology

Gabrielle Elizabeth Callander
Morenike Olorunda
Dominique Monna
Edi Schuepbach
Daniel Langenegger
Claudia Betschart
Samuel Hintermann
Dirk Behnke
Simona Cotesta
Markus Fendt

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00230

14,206 views
34 citations

Hypothesis and Theory

Published on 22 Nov 2013

A cholinergic hypothesis of the unconscious in affective disorders

in Neuropharmacology

Costa Vakalopoulos

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00220

11,581 views
7 citations

Original Research

Published on 19 Nov 2013

Synaptic interactions between perifornical lateral hypothalamic area, locus coeruleus nucleus and the oral pontine reticular nucleus are implicated in the stage succession during sleep-wakefulness cycle

in Neuropharmacology

Angel Nunez
Silvia Tortorella
Margarita Lucia Rodrigo-Angulo
Miguel Garzón

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00216

10,301 views
22 citations

Original Research

Published on 31 Oct 2013

Enhancement stimulants: perceived motivational and cognitive advantages

in Neuropharmacology

Irena P. Ilieva
Martha J. Farah

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00198

58,337 views
61 citations

Original Research

Published on 30 Oct 2013

Acute nicotine improves social decision-making in non-smoking but not in smoking schizophrenia patients

in Neuropharmacology

Charel Quisenaerts
Manuel Morrens
Wouter Hulstijn
Maarten Timmers
Peter de Boer
Bernard Sabbe
Ellen R.A. De Bruijn

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00197

8,037 views
16 citations

Hypothesis and Theory

Published on 15 Aug 2013

Mechanism Based Approaches for Rescuing and Enhancing Cognition

in Neuropharmacology

Gary Lynch
Christine M Gall

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00143

9,713 views
29 citations

Original Research

Published on 31 Jul 2013

Wfs1-deficient mice display altered function of serotonergic system and increased behavioral response to antidepressants

in Neuropharmacology

Tanel Visnapuu
Sirli Raud
Maarja Loomets
Riin Reimets
Silva Sütt
Hendrik Luuk
Mario Plaas
Sulev Kõks
Vallo Volke
Aet Alttoa

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00132

5,412 views
10 citations

Review

Published on 18 Jun 2013

Reward learning as a potential target for pharmacological augmentation of cognitive remediation for schizophrenia: a roadmap for preclinical development

in Neuropharmacology

Dean T Acheson
Elizabeth W Twamley
Jared W Young

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00103

6,495 views
24 citations

Original Research

Published on 13 Jun 2013

The effects of methylphenidate on cognitive performance of healthy male rats

in Neuropharmacology

Claire Louise Rostron
Elise Kaplan
Victoria Gaeta
Rachel Nigriello
Eleanor Jane Dommett

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00097

8,555 views
7 citations

Review

Published on 29 May 2013

Attention-deficit hyperactivity disorder (ADHD) stimulant medications as cognitive enhancers

in Neuropharmacology

Claire Diane Advokat
Mindy Scheithauer

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00082

114,963 views
56 citations

General Commentary

Published on 01 May 2013

Erratum: The promise of neuroprotective agents in Parkinson's disease

in Neuropharmacology

Stacey E Seidl
Judith Potashkin

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00069

3,594 views
2 citations

Original Research

Published on 26 Feb 2013

The Effect of Nicotinamide on Gene Expression in a Traumatic Brain Injury Model

in Neuropharmacology

Gail D Anderson
Todd C Peterson
Fred M Farin
Theo K Bammler
Richard P Beyer
Eric D Kantor
Michael Hoane

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00021

7,444 views
18 citations

Review

Published on 26 Jul 2012

Critical Evaluation of Ayurvedic Plants for Stimulating Intrinsic Antioxidant Response

in Neuropharmacology

Sunil Dutt Shukla
Maheep Bhatnagar
Sukant Khurana

Frontiers in Neuroscience

doi 10.3389/fnins.2012.00112

36,410 views
32 citations

1,063 articles

articles

The hypocretin/orexin antagonist almorexant promotes sleep without impairment of performance in rats

Characterization of early cortical population response to thalamocortical input in vitro

Effects of a newly developed potent orexin-2 receptor-selective antagonist, compound 1 m, on sleep/wakefulness states in mice

LSN2424100: a novel, potent orexin-2 receptor antagonist with selectivity over orexin-1 receptors and activity in an animal model predictive of antidepressant-like efficacy

Orexin, orexin receptor antagonists and central cardiovascular control

Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulators

Differential actions of orexin receptors in brainstem cholinergic and monoaminergic neurons revealed by receptor knockouts: implications for orexinergic signaling in arousal and narcolepsy

Cannabinoid-hypocretin cross-talk in the central nervous system: what we know so far

Dynorphin B induces lateral asymmetric changes in feline spinal cord reflexes

Is memantine a potential therapeutic for Rett syndrome?

Distinct effects of IPSU and suvorexant on mouse sleep architecture

Kinetic properties of “dual” orexin receptor antagonists at OX1R and OX2R orexin receptors

A cholinergic hypothesis of the unconscious in affective disorders

Synaptic interactions between perifornical lateral hypothalamic area, locus coeruleus nucleus and the oral pontine reticular nucleus are implicated in the stage succession during sleep-wakefulness cycle

Enhancement stimulants: perceived motivational and cognitive advantages

Acute nicotine improves social decision-making in non-smoking but not in smoking schizophrenia patients

Mechanism Based Approaches for Rescuing and Enhancing Cognition

Wfs1-deficient mice display altered function of serotonergic system and increased behavioral response to antidepressants

Reward learning as a potential target for pharmacological augmentation of cognitive remediation for schizophrenia: a roadmap for preclinical development

The effects of methylphenidate on cognitive performance of healthy male rats

Attention-deficit hyperactivity disorder (ADHD) stimulant medications as cognitive enhancers

Erratum: The promise of neuroprotective agents in Parkinson's disease

The Effect of Nicotinamide on Gene Expression in a Traumatic Brain Injury Model

Critical Evaluation of Ayurvedic Plants for Stimulating Intrinsic Antioxidant Response