Frontiers in Oncology | Cancer Genetics

Original Research

Published on 01 Jul 2025

SPP1+ tumor-associated macrophages define a high-risk subgroup and inform personalized therapy in hepatocellular carcinoma

in Cancer Genetics

Wei-Xuan Xu
Ya-Mei Ye
Jia-Lin Chen
Xin-Ying Guo
Chen Li
Juan Luo
Lin-Bin Lu
Xiong Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1606195

371 views

Original Research

Accepted on 30 Jun 2025

To explore the prognostic efficacy and mechanism of ABCC5 clinical scoring model in Hepatocellular carcinoma

in Cancer Genetics

Yu Deng
Ning Yang
Chengyu Huang
Meiting Long
Junming Wu
Ke Mo
Zijun Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1519533

Original Research

Accepted on 25 Jun 2025

RNLS promotes ovarian cancer growth and inhibits ferroptosis via mediating STAT3

in Cancer Genetics

Liang Lin
Zuolian Xie
Peilin Zhong
Jian Chen
Ning Ma
Ling Li
Li Chen
An Lin

Frontiers in Oncology

doi 10.3389/fonc.2025.1604377

Original Research

Published on 18 Jun 2025

Deciphering the impact of intra-tumoral bacterial infiltration on multi-omics profiles in low-grade gliomas

in Cancer Genetics

Wenshu Li
Zixiang Zhu
Longyuan Li
Xin Wu
Jiaxuan Li
Yi Zhou
Lingwen Gu
Pranathi Vittal
Zhouqing Chen
Zhong Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1582068

338 views

Review

Accepted on 17 Jun 2025

The prognostic and predictive value of peripheral immune-related proteins in patients with lung cancer treated with radiotherapy

in Cancer Genetics

Shaowen Lyu
Rianne D.W. Vaes
Francesco Cortiula
Lizza E.L. Hendriks
Marc A. Vooijs
Dirk De Ruysscher

Frontiers in Oncology

doi 10.3389/fonc.2025.1625212

147 views

Original Research

Accepted on 11 Jun 2025

TLR4/MyD88 Expression Patterns and Novel Genetic Variants: Association with Aggressive Clinicopathological Features in Colorectal Cancer

in Cancer Genetics

Tra Thai Dang
Nhat Viet Pham
Dung Ngoc Tran
Hang Thu Ngo
Mao Van Can
Hoang Huy Nguyen
Xuan Thi Nguyen
Chung Thanh Dang

Frontiers in Oncology

doi 10.3389/fonc.2025.1568729

151 views

Perspective

Published on 09 Jun 2025

Personalized preventive medicine using genomic information: future perspective and corresponding research plan

in Cancer Genetics

Hiroto Narimatsu
Kaname Watanabe
Ann Sato
Eri Haneda
Masumi Okamoto
Haruka Nakada
Sho Nakamura

Frontiers in Oncology

doi 10.3389/fonc.2025.1599753

857 views

Case Report

Published on 06 Jun 2025

Primary pancreas NTRK-rearranged neoplasm harboring an EVT6::NTRK3 fusion with a sclerosing epithelioid fibrosarcoma morphology: a case report and comprehensive review of the literature

in Cancer Genetics

Xin Wu
Dujuan Li
Fangfang Fu
Lifei Lian

Frontiers in Oncology

doi 10.3389/fonc.2025.1526281

981 views

Original Research

Published on 05 Jun 2025

EPHX2 overexpression deters the advancement of clear cell renal cell carcinoma via lipid metabolism reprogramming

in Cancer Genetics

Bo Guan
Cong Huang
Jun He
Weimin Shan
Di Cui
Xiaowei Li
Chaozhao Liang
Zongyao Hao

Frontiers in Oncology

doi 10.3389/fonc.2025.1541429

861 views

Review

Published on 04 Jun 2025

The role of MYEOV gene: a review and future directions

in Cancer Genetics

Yidan Xi
Xuefei Liu
Yanan Ge
Mingzhe Jiang
Dong Zhao
Ershu Zhao
Fei Cai
Xinlong Wang
Jiatong Li
Tingting Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1543590

769 views

Review

Published on 02 Jun 2025

The regulatory network of epithelial-mesenchymal transition-associated non-coding RNAs in thyroid cancer: molecular mechanisms, clinical implications, and therapeutic strategies

in Cancer Genetics

Rui Zhao
Jiaju Tian
Jing Peng
Ruiting Ma
Songbo Fu

Frontiers in Oncology

doi 10.3389/fonc.2025.1592467

917 views

Case Report

Published on 30 May 2025

Case Report: Biallelic BRCA1 pathogenic alterations in a Fanconi Anemia patient and clinical implications of variant location

in Cancer Genetics

Colin C. Young
Ashley Lahr
Caroline Nestor
Ashley Kaminski
Marcy E. Richardson
Georgianne L. Arnold

Frontiers in Oncology

doi 10.3389/fonc.2025.1572310

1,212 views

Case Report

Published on 30 May 2025

Case Report: Influence of BRCA1 germline mutation on treatment-related morbidity of a non-seminomatous germ cell tumor patient

in Cancer Genetics

Bruno Griesler
Susann Schulze
Thomas Kegel
Christine Dierks
Pablo Villavicencio-Lorini
Markus Eszlinger
Haifa Kathrin Al-Ali
Nadja Jaekel

Frontiers in Oncology

doi 10.3389/fonc.2025.1579574

664 views

Original Research

Published on 29 May 2025

Genomic profiles and prognostic biomarkers of resectable lung adenocarcinoma with a micropapillary component

in Cancer Genetics

Jiafu Zhu
Xinhai Sun
Jiangshan Huang
Wenwei Lin
Yanyan Zhan
Junrong Yan
Yang Xu
Long Wu
Yuane Lian
Zhenyang Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1574817

627 views

Original Research

Published on 29 May 2025

Leaf-vein-inspired multi-organ microfluidic chip for modeling breast cancer CTC organotropism

in Cancer Genetics

Liuyin Liu
Xiaoli Qu
Zhe Wang
Cheng Ji
Rui Ling
Changjiao Yan

Frontiers in Oncology

doi 10.3389/fonc.2025.1602225

981 views

Original Research

Published on 27 May 2025

GNG7 as a tumor-suppressor gene in lung adenocarcinoma: implications for prognosis and immune-based therapies

in Cancer Genetics

Kexin Luo
Meihan Liu
Zhongqin Peng
Haiyang Zhao
Guoyi Li
Yuanze Cai
Yumeng Lei
Hongpan Zhang
Yongsheng Zhao

Frontiers in Oncology

doi 10.3389/fonc.2025.1588646

723 views