Frontiers in Oncology | Cancer Genetics

Original Research

Published on 06 Jul 2023

Molecular profiling of solid tumors by next-generation sequencing: an experience from a clinical laboratory

in Cancer Genetics

Pratibha Bhai
Jacob Turowec
Stephanie Santos
Jennifer Kerkhof
LeeAnne Pickard
Aidin Foroutan
Daniel Breadner
Matthew Cecchini
Michael A. Levy
Alan Stuart

Frontiers in Oncology

doi 10.3389/fonc.2023.1208244

6,101 views
3 citations

Original Research

Published on 04 Jul 2023

Computational pharmacogenotype extraction from clinical next-generation sequencing

in Cancer Genetics

Tyler Shugg
Reynold C. Ly
Wilberforce Osei
Elizabeth J. Rowe
Caitlin A. Granfield
Ty C. Lynnes
Elizabeth B. Medeiros
Jennelle C. Hodge
Amy M. Breman
Bryan P. Schneider

Frontiers in Oncology

doi 10.3389/fonc.2023.1199741

5,286 views
8 citations

Editorial

Published on 04 Jul 2023

Editorial: Methods in cancer genetics

in Cancer Genetics

Simona D’Aguanno
Pawel Buczkowicz

Frontiers in Oncology

doi 10.3389/fonc.2023.1227854

1,233 views

Case Report

Published on 04 Jul 2023

Solitary fibrous tumor with IGF-II-induced non-islet cell tumor hypoglycemia: a case report and molecular characterization by next-generation sequencing

in Cancer Genetics

Helvijs Niedra
Ilze Konrade
Raitis Peculis
Sergejs Isajevs
Rihards Saksis
Roberts Skapars
Armands Sivins
Beate Elizabete Daukste
Dace Mezaka
Vita Rovite

Frontiers in Oncology

doi 10.3389/fonc.2023.1188579

2,731 views
3 citations

Case Report

Published on 30 Jun 2023

Case Report: SMARCA4 (BRG1)-deficient undifferentiated carcinoma of gallbladder with genetic analysis

in Cancer Genetics

Xiangpeng Meng
Jia Ma
Nan Meng
Tianyu Yun
Beifang Niu

Frontiers in Oncology

doi 10.3389/fonc.2023.1086266

4,100 views
3 citations

Hypothesis and Theory

Published on 29 Jun 2023

A non-mutated TROP2 fingerprint in cancer genetics

in Cancer Genetics

Emanuela Guerra
Roberta Di Pietro
Gianmarco Stati
Saverio Alberti

Frontiers in Oncology

doi 10.3389/fonc.2023.1151090

3,794 views
5 citations

Review

Published on 28 Jun 2023

Extrachromosomal DNA (ecDNA) in cancer: mechanisms, functions, and clinical implications

in Cancer Genetics

Yucheng Dong
Qi He
Xinyu Chen
Fan Yang
Li He
Yongchang Zheng

Frontiers in Oncology

doi 10.3389/fonc.2023.1194405

19,065 views
14 citations

Original Research

Published on 26 Jun 2023

Biallelic disruption of DDX41 activity is associated with distinct genomic and immunophenotypic hallmarks in acute leukemia

in Cancer Genetics

Anne Tierens
Elizabeth Kagotho
Satoru Shinriki
Andrew Seto
Adam C. Smith
Melanie Care
Dawn Maze
Hassan Sibai
Karen W. Yee
Andre C. Schuh

Frontiers in Oncology

doi 10.3389/fonc.2023.1153082

5,128 views
5 citations

Case Report

Published on 22 Jun 2023

Unveiling the genomic landscape of possible metastatic malignant transformation of teratoma secondary to cisplatin-chemotherapy: a Tempus gene analysis-based case report literature review

in Cancer Genetics

Christian M. Farag
Elena K. Johnston
Ryan M. Antar
Shaher G. Issa
Qasim Gadiwalla
Zoon Tariq
Sun A. Kim
Michael J. Whalen

Frontiers in Oncology

doi 10.3389/fonc.2023.1192843

2,937 views
5 citations

Original Research

Published on 20 Jun 2023

Construction of an M2 macrophage-related prognostic model in hepatocellular carcinoma

in Cancer Genetics

Huangqin Song
Xiaoxiao Wang
Chao Zhang
Jiefeng He

Frontiers in Oncology

doi 10.3389/fonc.2023.1170775

5,921 views
8 citations

Editorial

Published on 19 Jun 2023

Editorial: Interplay between epigenetic modifiers and transcription factors in driving cancer progression

in Cancer Genetics

Yongyong Yang
Annalisa Di Ruscio
Satoshi Inoue
Guocan Wang
Shuai Gao

Frontiers in Oncology

doi 10.3389/fonc.2023.1211537

2,015 views

Original Research

Published on 15 Jun 2023

Integration analysis of single-cell and spatial transcriptomics reveal the cellular heterogeneity landscape in glioblastoma and establish a polygenic risk model

in Cancer Genetics

Yaxuan Liu
Zhenyu Wu
Yueyuan Feng
Jiawei Gao
Bo Wang
Changlin Lian
Bo Diao

Frontiers in Oncology

doi 10.3389/fonc.2023.1109037

7,172 views
14 citations

Original Research

Published on 14 Jun 2023

Chronic obstructive pulmonary disease alters the genetic landscape and tumor immune microenvironment in lung cancer patients

in Cancer Genetics

Qiurui Zhang
Xijia Feng
Weiting Hu
Chengqiang Li
Debin Sun
Zhao Peng
Shengzhou Wang
Hecheng Li
Min Zhou

Frontiers in Oncology

doi 10.3389/fonc.2023.1169874

3,817 views
4 citations

Original Research

Published on 12 Jun 2023

Flux estimation analysis systematically characterizes the metabolic shifts of the central metabolism pathway in human cancer

in Cancer Genetics

Grace Yang
Shaoyang Huang
Kevin Hu
Alex Lu
Jonathan Yang
Noah Meroueh
Pengtao Dang
Yijie Wang
Haiqi Zhu
Sha Cao

Frontiers in Oncology

doi 10.3389/fonc.2023.1117810

3,579 views

Original Research

Published on 12 Jun 2023

Longitudinal characterization of primary osteosarcoma and derived subcutaneous and orthotopic relapsed patient-derived xenograft models

in Cancer Genetics

Maria Eugenia Marques da Costa
Robin Droit
Pierre Khneisser
Anne Gomez-Brouchet
Tiphaine Adam-de-Beaumais
Marie Nolla
Nicolas Signolles
Jacob Torrejon
Bérangère Lombard
Damarys Loew

Frontiers in Oncology

doi 10.3389/fonc.2023.1166063

4,762 views
4 citations

Original Research

Published on 09 Jun 2023

Bioinformatics and pathway enrichment analysis identified hub genes and potential biomarker for gastric cancer prognosis

in Cancer Genetics

Elham Darang
Zahra Pezeshkian
Seyed Ziaeddin Mirhoseini
Shahrokh Ghovvati

Frontiers in Oncology

doi 10.3389/fonc.2023.1187521

6,328 views
13 citations