Frontiers in Oncology | Cancer Genetics

Original Research

Published on 29 May 2025

Genomic profiles and prognostic biomarkers of resectable lung adenocarcinoma with a micropapillary component

in Cancer Genetics

Jiafu Zhu
Xinhai Sun
Jiangshan Huang
Wenwei Lin
Yanyan Zhan
Junrong Yan
Yang Xu
Long Wu
Yuane Lian
Zhenyang Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1574817

1,930 views
2 citations

Original Research

Published on 29 May 2025

Leaf-vein-inspired multi-organ microfluidic chip for modeling breast cancer CTC organotropism

in Cancer Genetics

Liuyin Liu
Xiaoli Qu
Zhe Wang
Cheng Ji
Rui Ling
Changjiao Yan

Frontiers in Oncology

doi 10.3389/fonc.2025.1602225

4,167 views
4 citations

Original Research

Published on 27 May 2025

GNG7 as a tumor-suppressor gene in lung adenocarcinoma: implications for prognosis and immune-based therapies

in Cancer Genetics

Kexin Luo
Meihan Liu
Zhongqin Peng
Haiyang Zhao
Guoyi Li
Yuanze Cai
Yumeng Lei
Hongpan Zhang
Yongsheng Zhao

Frontiers in Oncology

doi 10.3389/fonc.2025.1588646

1,843 views
2 citations

Original Research

Published on 26 May 2025

Promoter hypermethylation of SFRP1 is an allele fraction-dependent prognostic biomarker in metastatic pancreatic ductal adenocarcinoma

in Cancer Genetics

Benjamin Stubbe
Malene P. Stoico
Simone K. Terp
Poul H. Madsen
Søren Lundbye-Christensen
Carsten P. Hansen
Laurids Ø. Poulsen
Louise S. Rasmussen
Mette N. Yilmaz
Lars H. Jensen

Frontiers in Oncology

doi 10.3389/fonc.2025.1568386

1,934 views

Original Research

Published on 21 May 2025

Early-stage endometrioid carcinoma with MSH6 protein deficiency: pitfalls in the diagnostic interpretation of microsatellite instability

in Cancer Genetics

Cheng Wang
Dongni Liang
Wei Wang
Wei Kuang
Juan Zou
Jing Zeng
Min Feng

Frontiers in Oncology

doi 10.3389/fonc.2025.1520500

2,609 views
1 citation

Original Research

Published on 19 May 2025

Identification of novel prognostic biomarkers for thyroid cancer by integrated transcriptome analysis of metastasis-associated genes

in Cancer Genetics

Bushra Alnwisser
Salman Alshehri
Amal Qattan
Minjing Zou
Abdelilah Aboussekhra
Ali S. Alzahrani
Yufei Shi

Frontiers in Oncology

doi 10.3389/fonc.2025.1536270

3,886 views
2 citations

Original Research

Published on 19 May 2025

Integrating next-generation sequencing and artificial intelligence for the identification and validation of pathogenic variants in colorectal cancer

in Cancer Genetics

Juliana Rodriguez-Salamanca
Mariana Angulo-Aguado
Sarah Orjuela-Amarillo
Catalina Duque
Diana Carolina Sierra-Díaz
Nora Contreras Bravo
Carlos Figueroa
Carlos M. Restrepo
Andrés López-Cortés
Rodrigo Cabrera

Frontiers in Oncology

doi 10.3389/fonc.2025.1568205

12,331 views
1 citation

Case Report

Published on 13 May 2025

Case Report: Retroperitoneal dedifferentiated solitary fibrous tumor with unexpected Pax-2 expression, mimicking high grade clear cell renal cell carcinoma

in Cancer Genetics

Jia Wei
Chen-chen Yao
Yue-Fen Zou
Yong-Zhong Wei
Qin-he Fan
Qi-xing Gong

Frontiers in Oncology

doi 10.3389/fonc.2025.1569160

1,678 views

Original Research

Published on 08 May 2025

Revisiting the molecular landscape of Rosai-Dorfman disease: insights from whole exome sequencing of Saudi patients

in Cancer Genetics

Sarah Binhassan
Manar Samman
Yazeed Al-Sheikh
Wafaa Alshakweer
Tahani Alhalouli
Najd Alshamlan
Manal Abudawood

Frontiers in Oncology

doi 10.3389/fonc.2025.1556830

2,342 views
1 citation

Original Research

Published on 06 May 2025

A proteotranscriptomic approach to dissect the molecular landscape of human retinoblastoma

in Cancer Genetics

Julian Wolf
Rozina Ida Hajdu
Stefaniya Boneva
Ira Godbole
Lucas Stürzbecher
Claudia Auw-Haedrich
Wolf A. Lagrèze
Hansjürgen Agostini
Thomas Reinhard
Stefan Tholen

Frontiers in Oncology

doi 10.3389/fonc.2025.1571702

2,986 views

Case Report

Published on 02 May 2025

Comparative analysis of whole-genome sequencing of tumor and cfDNA in a neuroblastoma patient: a case report

in Cancer Genetics

Susanne Fransson
Kleopatra Georgantzi
Anna Djos
Jennie Gaarder
Johanna Svensson
Vimala Anthonydhason
Per Kogner
Tommy Martinsson
Ganesh Umapathy

Frontiers in Oncology

doi 10.3389/fonc.2025.1569520

3,083 views

Original Research

Published on 15 Apr 2025

Down-regulation of miR-125b by HPV16 E6 might promote cervical cancer progression through TAZ/TEAD

in Cancer Genetics

Yongli Hou
Lili Zhang
Wenhao Wang
Keyan Cheng
Hui Wang
Yanfei Ji
Xiaoqiang Su
Min Hao

Frontiers in Oncology

doi 10.3389/fonc.2025.1444874

1,692 views
3 citations

Original Research

Published on 08 Apr 2025

5hmC-profiles in Puerto Rican Hispanic/Latino men with aggressive prostate cancer

in Cancer Genetics

Manishkumar S. Patel
Mousa Almubarak
Jaime Matta
Carmen Ortiz-Sanchez
Jarline Encarnacion
Gilberto Ruiz-Deya
Julie Dutil
Jasreman Dhillon
Kosj Yamoah
Anders Berglund

Frontiers in Oncology

doi 10.3389/fonc.2025.1541878

2,732 views
1 citation

Case Report

Published on 04 Apr 2025

Cerebral CIC-NUTM1 rearrangement sarcoma- case report and review of the literature

in Cancer Genetics

Wei Jin
Ke Dong
Fan Yang
Jianning Zhang
Gang Cheng

Frontiers in Oncology

doi 10.3389/fonc.2025.1519335

2,422 views
1 citation

Case Report

Published on 04 Apr 2025

Case Report: Myeloid neoplasms with the t(3;12)(q26.2;p13.1)/MECOM-ETV6 translocation: report of two new cases and review of the literature

in Cancer Genetics

Soumya Mikkilineni
Juan Pablo Pineda-Reyes
Lindsay Wilde
Andres Ferber
Zi-Xuan Wang
Stephen Peiper
Guldeep Uppal
Jerald Gong
Jinglan Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1526044

2,435 views
2 citations

Original Research

Published on 01 Apr 2025

EFTUD2 is a promising diagnostic and prognostic indicator involved in the tumor immune microenvironment and glycolysis of lung adenocarcinoma

in Cancer Genetics

Ankang Yin
Yufan Xu
Xiyang Su
Runan Wang
Zebin Zhang
Yi Chen
Lu Han
Guoxiang Fu
Wei Wang
Juan Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1499217

3,266 views

Original Research

Published on 25 Mar 2025

Discovery of a DNA repair-associated radiosensitivity index for predicting radiotherapy efficacy in breast cancer

in Cancer Genetics

Jianguang Lin
Hainan Yang
Rongfu Huang
Tianwen Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1439516

2,789 views
1 citation

Original Research

Published on 06 Mar 2025

Association of the IL-10 and IL-18 polymorphisms with nasopharyngeal carcinoma risk

in Cancer Genetics

Xueru Chen
Ruibin Zhang
Hui Xie
Sha Li
Jincai Guo
Yan Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1543182

1,579 views

Original Research

Published on 04 Mar 2025

Multi-omics approach reveals the impact of prognosis model-related genes on the tumor microenvironment in medulloblastoma

in Cancer Genetics

Dongming Han
Xuan Chen
Xin Jin
Jiankang Li
Dongyang Wang
Ziwei Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1477617

4,347 views

Case Report

Published on 19 Feb 2025

Case report: The smallest 9p21.3 microdeletion involving CDKN2A but not CDKN2B causes multiple plexiform neurofibromas

in Cancer Genetics

Yuanyuan Zhang
Xiang Li
Haiming Gao
Chuang Qiu
Xiaoliang Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1437093

1,970 views
1 citation

Original Research

Published on 18 Feb 2025

Reclassification of variants of uncertain significance by race, ethnicity, and ancestry for patients at risk for breast cancer

in Cancer Genetics

Versha Pleasant
Jordyn Boggan
Blair Richards
Kara J. Milliron
Kristen S. Purrington
Michael Simon
Sofia Merajver

Frontiers in Oncology

doi 10.3389/fonc.2025.1455509

3,694 views
5 citations

Review

Published on 14 Feb 2025

The role of telomere and telomerase in cancer and novel therapeutic target: narrative review

in Cancer Genetics

Temesgen Baylie
Mohammed Jemal
Gelagay Baye
Mamaru Getinet
Gashaw Azanaw Amare
Adane Adugna
Desalegn Abebaw
Zigale Hibstu
Bantayehu Addis Tegegne
Endalkachew Gugsa

Frontiers in Oncology

doi 10.3389/fonc.2025.1542930

11,843 views
8 citations

Original Research

Published on 13 Feb 2025

The human 18S rRNA m6A methyltransferase METTL5 promotes tumorigenesis via DEPDC1 in lung squamous cell carcinoma

in Cancer Genetics

Yang Yan
Jianjun Fu

Frontiers in Oncology

doi 10.3389/fonc.2025.1522157

2,363 views
2 citations

Editorial

Published on 11 Feb 2025

Editorial: Non-coding RNAs in breast cancer, volume II

in Cancer Genetics

Wenwen Zhang
Naoyuki Kataoka
Xiaoxiang Guan

Frontiers in Oncology

doi 10.3389/fonc.2025.1561190

1,249 views

1,231 articles

articles

Genomic profiles and prognostic biomarkers of resectable lung adenocarcinoma with a micropapillary component

Leaf-vein-inspired multi-organ microfluidic chip for modeling breast cancer CTC organotropism

GNG7 as a tumor-suppressor gene in lung adenocarcinoma: implications for prognosis and immune-based therapies

Promoter hypermethylation of SFRP1 is an allele fraction-dependent prognostic biomarker in metastatic pancreatic ductal adenocarcinoma

Early-stage endometrioid carcinoma with MSH6 protein deficiency: pitfalls in the diagnostic interpretation of microsatellite instability

Identification of novel prognostic biomarkers for thyroid cancer by integrated transcriptome analysis of metastasis-associated genes

Integrating next-generation sequencing and artificial intelligence for the identification and validation of pathogenic variants in colorectal cancer

Case Report: Retroperitoneal dedifferentiated solitary fibrous tumor with unexpected Pax-2 expression, mimicking high grade clear cell renal cell carcinoma

Revisiting the molecular landscape of Rosai-Dorfman disease: insights from whole exome sequencing of Saudi patients

A proteotranscriptomic approach to dissect the molecular landscape of human retinoblastoma

Comparative analysis of whole-genome sequencing of tumor and cfDNA in a neuroblastoma patient: a case report

Down-regulation of miR-125b by HPV16 E6 might promote cervical cancer progression through TAZ/TEAD

5hmC-profiles in Puerto Rican Hispanic/Latino men with aggressive prostate cancer

Cerebral CIC-NUTM1 rearrangement sarcoma- case report and review of the literature

Case Report: Myeloid neoplasms with the t(3;12)(q26.2;p13.1)/MECOM-ETV6 translocation: report of two new cases and review of the literature

EFTUD2 is a promising diagnostic and prognostic indicator involved in the tumor immune microenvironment and glycolysis of lung adenocarcinoma

Discovery of a DNA repair-associated radiosensitivity index for predicting radiotherapy efficacy in breast cancer

Association of the IL-10 and IL-18 polymorphisms with nasopharyngeal carcinoma risk

Multi-omics approach reveals the impact of prognosis model-related genes on the tumor microenvironment in medulloblastoma

Case report: The smallest 9p21.3 microdeletion involving CDKN2A but not CDKN2B causes multiple plexiform neurofibromas

Reclassification of variants of uncertain significance by race, ethnicity, and ancestry for patients at risk for breast cancer

The role of telomere and telomerase in cancer and novel therapeutic target: narrative review

The human 18S rRNA m6A methyltransferase METTL5 promotes tumorigenesis via DEPDC1 in lung squamous cell carcinoma

Editorial: Non-coding RNAs in breast cancer, volume II