Frontiers in Oncology | Cancer Immunity and Immunotherapy

Review

Accepted on 13 Feb 2026

The Role of MiRNA-Mediated Tumor Microenvironment in Bone Metastasis from a Multi-Omics Perspective: Cross-Cancer Mechanisms and Clinical Translation

in Cancer Immunity and Immunotherapy

Zhuo Gu
Shu-fen Zhu
Peng-fei Li

Frontiers in Oncology

127 views

Original Research

Published on 13 Feb 2026

The value of T1 mapping and intravoxel incoherent motion parameters in predicting PD-L1 expression and dynamically monitoring immunotherapy in advanced lung cancer

in Cancer Immunity and Immunotherapy

Qijia Han
Shulin Li
Zhiming Xiang

Frontiers in Oncology

doi 10.3389/fonc.2026.1687192

223 views

Case Report

Published on 12 Feb 2026

Case Report: Complete response to the concurrent neoadjuvant radiation therapy and pembrolizumab in a locally recurrent, chemotherapy-refractory undifferentiated pleomorphic sarcoma of bone

in Cancer Immunity and Immunotherapy

Brina A. Patel
Jason T. Smith
Sintawat Wangsiricharoen
Wei-Lien Wang
Patrick P. Lin
Ahsan Farooqi
Elise F. Nassif Haddad
Kamal Ummed
Alexander F. Mericli
David M. Adelman

Frontiers in Oncology

doi 10.3389/fonc.2026.1645629

316 views

Original Research

Accepted on 11 Feb 2026

Meta-Analysis of Tuberculosis Incidence and Risk in Cancer Patients Treated with Immune Checkpoint Inhibitors

in Cancer Immunity and Immunotherapy

Hui Ming
Xiaogang Chen
Biao Fu
Wenbing Hu
Hui Yu

Frontiers in Oncology

Original Research

Published on 11 Feb 2026

Association between splenic volume changes and prognosis in advanced gastric cancer patients receiving chemotherapy combined with immunotherapy

in Cancer Immunity and Immunotherapy

Zhiying Li
Weiwei Liu
Guilin Zhang
Xiaona Fu
Yi Li
Jie Lou
Bingxin Gong
Lingli Li
Lian Yang
Peng Zhang

Frontiers in Oncology

doi 10.3389/fonc.2026.1763993

414 views

Original Research

Accepted on 09 Feb 2026

cGAS/STING-mediated upregulation of NKG2D ligands in LSCs contributes to enhanced sensitivity to NK cells

in Cancer Immunity and Immunotherapy

Huifang Zhu
Yan Ouyang
Qin YiLin
Qianmin Zhang
Pengcheng Zhu

Frontiers in Oncology

Mini Review

Published on 05 Feb 2026

Overcoming immune resistance in ovarian cancer: checkpoint inhibitors, tumor microenvironment, and translational advances

in Cancer Immunity and Immunotherapy

Song Yue
Tao Wen
Xiaozhu Liu
Juan Tang
Yue Liu
Shengxian Peng

Frontiers in Oncology

doi 10.3389/fonc.2026.1762619

648 views

Mini Review

Published on 05 Feb 2026

Macrophage-based therapeutic strategies in glioblastoma: advancements in drug delivery and immunotherapy

in Cancer Immunity and Immunotherapy

Dongyang Li
Xinyue Zhang
Yanwei Du

Frontiers in Oncology

doi 10.3389/fonc.2026.1746344

522 views

Review

Accepted on 04 Feb 2026

The Non-Classical Immune Checkpoint HLA-G: A Regulatory Master Switch Governing Tolerance, Evasion, and Translational Frontiers

in Cancer Immunity and Immunotherapy

Huan Liu
Qiong Li
Lunli Li
Ying Xue
Xiaofei Xue
Pingping Xu

Frontiers in Oncology

Review

Published on 04 Feb 2026

Advancing CAR-T therapy in prostate cancer: overcoming the tumor microenvironment and enhancing efficacy

in Cancer Immunity and Immunotherapy

Zhongze Zhou
Yongfeng Lao
Kun Zhao
Long Cheng
Xi Xiao
Wenxuan Li
Shuai Liu
Xiangbin Kong
Zhilong Dong

Frontiers in Oncology

doi 10.3389/fonc.2026.1659869

724 views

Original Research

Published on 03 Feb 2026

Association of B7H3 with HIF-1α nuclear expression indicates poor prognosis and therapeutic potential in gastric cancer

in Cancer Immunity and Immunotherapy

Mengsi Li
Tianwei Guo
Ziyi Wang
Xue Liu
Lingchuan Guo
Lei Cao

Frontiers in Oncology

doi 10.3389/fonc.2026.1744341

463 views

Case Report

Accepted on 02 Feb 2026

Nivolumab Induces Seven-Year Sustained Remission in a Patient with Advanced PD-L1-Positive Lung Adenocarcinoma: A Case Report

in Cancer Immunity and Immunotherapy

Hongmei Sheng
Wei Zhang
Qihong Yu
Xing Wang
haiying peng

Frontiers in Oncology

199 views

Original Research

Accepted on 28 Jan 2026

Clinical outcomes and survival in patients with NSCLC and EGFR exon 20 mutations: Evidence from real-world clinical practice in a retrospective study in Galicia

in Cancer Immunity and Immunotherapy

Begoña CAMPOS
Martín Emilio Lázaro Quintela
María Carmen Areses Manrique
Cristina Azpitarte Raposeiras
Jorge García-González
Francisco Javier Afonso Afonso
Manuel Fernández-Bruno
Natalia Fernández Núñez
Raquel Romero Van der Schoot
Lucía Santomé Couto

Frontiers in Oncology

115 views

Original Research

Published on 28 Jan 2026

Role of Intermediate dose escalation of radiotherapy in the survival of unresectable stage III non-small cell lung cancer patients in the era of immunotherapy

in Cancer Immunity and Immunotherapy

Saber A. Amin
Chi Lin
Apar K. Ganti
Weining Ken Zhen
Chi Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1652522

544 views

Original Research

Published on 27 Jan 2026

Immuno−oncological effects of aerobic exercise combined with anti−PD−L1 antibody blockade in a murine breast cancer model

in Cancer Immunity and Immunotherapy

Amirhossein Ahmadi Hekmatikar
Hamid Agha-Alinejad
Aliakbar Yousefi-Ahmadipour
Mahdieh Molanouri Shamsi
D. Maryama Awang Daud

Frontiers in Oncology

doi 10.3389/fonc.2026.1671244

884 views

Correction

Accepted on 21 Jan 2026

Correction: Myeloid-driven immunosuppression in head and neck cancer: single-cell ATAC/RNA and spatial transcriptomic perspectives

in Cancer Immunity and Immunotherapy

Rui Luo
Yang Jianzheng
Zimeng Cao
Bing Li

Frontiers in Oncology

129 views

Review

Published on 21 Jan 2026

Emerging immunotherapeutic strategies for malignant serous effusions: current evidence and future directions

in Cancer Immunity and Immunotherapy

Weimin He
Xia He
Zhi Qiao
Yongsheng Wang

Frontiers in Oncology

doi 10.3389/fonc.2026.1757825

1,951 views

Review

Published on 21 Jan 2026

Recent advances in non-alcoholic steatohepatitis-associated hepatocellular carcinoma: immune cells, metabolic dysregulation, and therapeutic strategies

in Cancer Immunity and Immunotherapy

Lisi Liu
Xun Duan
Baozhao Ju

Frontiers in Oncology

doi 10.3389/fonc.2025.1744299

1,206 views

Original Research

Accepted on 20 Jan 2026

PSCA-directed nanosized bio-immune conjugates (NANO:BICs) enable selective uptake of TLR9 agonists in bladder cancer cells

in Cancer Immunity and Immunotherapy

Max Iltzsche
Nancy Wetterling
Lissy Jilek
Daniel Nahhas
Marlena Hesse
Stefanie Tietze
Achim Temme
Christian Thomas
Susanne Fuessel
Barbara Kind

Frontiers in Oncology

237 views

Review

Published on 19 Jan 2026

Advances in chimeric antigen receptor-natural killer cell therapy: from mechanisms and preclinical studies to clinical application

in Cancer Immunity and Immunotherapy

Tianyuan Ren
Fengjiang Wang
Xuan Liu
Jun Guo
Sitan Xie

Frontiers in Oncology

doi 10.3389/fonc.2025.1759796

1,251 views

Case Report

Published on 19 Jan 2026

Case Report: The double-edged sword: cytokine release syndrome and rapid tumor response in a patient treated with amivantamab and chemotherapy

in Cancer Immunity and Immunotherapy

Pengfei Cui
Guannan Sun
Gang Zhou
Xueguang Guo
Haili Huang
Jing Yang
Na Li
Jing Tan
Yi Hu
Dong Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1758359

941 views

Original Research

Published on 14 Jan 2026

The expression of mercaptopyruvate sulfurtransferase serves as a potential biomarker for prognostic stratification and immunotherapy in certain cancers

in Cancer Immunity and Immunotherapy

Boran Cui
Chenchen Xia
Li Yang
Xiaoyu Xi
Xinxin Gong
Yixi Liu
Cai Tian
Xiaoli Du
Jiexian Du
Zengfang Hao

Frontiers in Oncology

doi 10.3389/fonc.2025.1686443

982 views

Original Research

Published on 14 Jan 2026

In vivo detection of HER2-positive breast cancer and sentinel lymph node metastasis using activatable ICG-conjugated Trastuzumab

in Cancer Immunity and Immunotherapy

Yunpeng Liu
Mahendra Isa
Takahito Nakajima

Frontiers in Oncology

doi 10.3389/fonc.2025.1747065

623 views

Original Research

Published on 13 Jan 2026

A novel prognostic model for Hedgehog signaling pathway-related genes predicts the prognosis of hepatocellular carcinoma

in Cancer Immunity and Immunotherapy

Ting Liu
Yang Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1674924

682 views

1,585 articles

articles

The Role of MiRNA-Mediated Tumor Microenvironment in Bone Metastasis from a Multi-Omics Perspective: Cross-Cancer Mechanisms and Clinical Translation

The value of T1 mapping and intravoxel incoherent motion parameters in predicting PD-L1 expression and dynamically monitoring immunotherapy in advanced lung cancer

Case Report: Complete response to the concurrent neoadjuvant radiation therapy and pembrolizumab in a locally recurrent, chemotherapy-refractory undifferentiated pleomorphic sarcoma of bone

Meta-Analysis of Tuberculosis Incidence and Risk in Cancer Patients Treated with Immune Checkpoint Inhibitors

Association between splenic volume changes and prognosis in advanced gastric cancer patients receiving chemotherapy combined with immunotherapy

cGAS/STING-mediated upregulation of NKG2D ligands in LSCs contributes to enhanced sensitivity to NK cells

Overcoming immune resistance in ovarian cancer: checkpoint inhibitors, tumor microenvironment, and translational advances

Macrophage-based therapeutic strategies in glioblastoma: advancements in drug delivery and immunotherapy

The Non-Classical Immune Checkpoint HLA-G: A Regulatory Master Switch Governing Tolerance, Evasion, and Translational Frontiers

Advancing CAR-T therapy in prostate cancer: overcoming the tumor microenvironment and enhancing efficacy

Association of B7H3 with HIF-1α nuclear expression indicates poor prognosis and therapeutic potential in gastric cancer

Nivolumab Induces Seven-Year Sustained Remission in a Patient with Advanced PD-L1-Positive Lung Adenocarcinoma: A Case Report

Clinical outcomes and survival in patients with NSCLC and EGFR exon 20 mutations: Evidence from real-world clinical practice in a retrospective study in Galicia

Role of Intermediate dose escalation of radiotherapy in the survival of unresectable stage III non-small cell lung cancer patients in the era of immunotherapy

Immuno−oncological effects of aerobic exercise combined with anti−PD−L1 antibody blockade in a murine breast cancer model

Correction: Myeloid-driven immunosuppression in head and neck cancer: single-cell ATAC/RNA and spatial transcriptomic perspectives

Emerging immunotherapeutic strategies for malignant serous effusions: current evidence and future directions

Recent advances in non-alcoholic steatohepatitis-associated hepatocellular carcinoma: immune cells, metabolic dysregulation, and therapeutic strategies

PSCA-directed nanosized bio-immune conjugates (NANO:BICs) enable selective uptake of TLR9 agonists in bladder cancer cells

Advances in chimeric antigen receptor-natural killer cell therapy: from mechanisms and preclinical studies to clinical application

Case Report: The double-edged sword: cytokine release syndrome and rapid tumor response in a patient treated with amivantamab and chemotherapy

The expression of mercaptopyruvate sulfurtransferase serves as a potential biomarker for prognostic stratification and immunotherapy in certain cancers

In vivo detection of HER2-positive breast cancer and sentinel lymph node metastasis using activatable ICG-conjugated Trastuzumab

A novel prognostic model for Hedgehog signaling pathway-related genes predicts the prognosis of hepatocellular carcinoma