Frontiers in Oncology | Cancer Molecular Targets and Therapeutics

Original Research

Accepted on 24 Jun 2025

Identification of novel molecular subtypes and construction of a prognostic signature via multi-omics analysis and machine learning in lung adenocarcinoma

in Cancer Molecular Targets and Therapeutics

Ke Ma
Jie Xu
Congyue Wang
Xu Cao
Wenjie Yu
Jingjing Xi
Xuan Zhang
Jiamin Zhan
Yang Liu
Aoyang Yu

Frontiers in Oncology

doi 10.3389/fonc.2025.1590216

140 views

Original Research

Published on 24 Jun 2025

Network pharmacology integrated with molecular docking and experimental validation elucidates the therapeutic potential of Forsythiae Fructus extract against hepatitis B virus-related hepatocellular carcinoma

in Cancer Molecular Targets and Therapeutics

Fuqing Chen
Yifan Cai
Changzhou Chen
Jianyin Zhou

Frontiers in Oncology

doi 10.3389/fonc.2025.1571537

348 views

Original Research

Accepted on 23 Jun 2025

Lamins regulate cancer cell plasticity and chemosensitivity

in Cancer Molecular Targets and Therapeutics

Guofang Chen
Tingyi Wei
Ao Huang
Junwei Shen
Furong Ju
Shichao Huang
Haisen Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1599175

125 views

Original Research

Accepted on 23 Jun 2025

Glyoxalase 1 (GLO-1) Gene Expression in Various Types of Cancer Cells Immunopathology: A Pan-Cancer Analysis Study

in Cancer Molecular Targets and Therapeutics

Ali ALASEEM
JEHAD ALDALI
Glowi Alasiri
Muhanad Alhujaily
Khalid I Alhussaini

Frontiers in Oncology

doi 10.3389/fonc.2025.1610886

152 views

Original Research

Published on 23 Jun 2025

In silico design and in vitro validation of a multi-epitope peptide vaccine targeting triple-negative breast cancer

in Cancer Molecular Targets and Therapeutics

Pengjun Zhou
Xing Shi
Jinquan Xia
Hong Hu

Frontiers in Oncology

doi 10.3389/fonc.2025.1611991

420 views

Review

Published on 23 Jun 2025

Molecular markers for the efficacy of neoadjuvant immunotherapy for head and neck squamous cell carcinoma

in Cancer Molecular Targets and Therapeutics

Jiabin Zhu
Yudong Ning

Frontiers in Oncology

doi 10.3389/fonc.2025.1586130

307 views

Review

Accepted on 20 Jun 2025

The NLRP3 Inflammasome in Urogenital Cancers: Structure, Dual Function, and Therapeutic Potential

in Cancer Molecular Targets and Therapeutics

Weiming Sun
Ruiting Ma
Rui Zhao
Jiaju Tian
Wenhui Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1593774

Systematic Review

Published on 20 Jun 2025

Efficacy and safety of Sacituzumab govitecan in solid tumors: a systematic review and meta-analysis

in Cancer Molecular Targets and Therapeutics

Yaping Zhang
Jian Chen
Xiaoyan Wang
Hui Wang
Xiaoli Chen
Jianfeng Hong
Hongming Fang

Frontiers in Oncology

doi 10.3389/fonc.2025.1624386

387 views

Original Research

Published on 20 Jun 2025

Risk factors for adverse reactions caused by abemaciclib in breast cancer therapy

in Cancer Molecular Targets and Therapeutics

Xianghua Quan
CaiHong Sun
Bing Han
ChuanZhou Zhang
HuaiQin Cang
Xiaomin Xing
Qie Guo

Frontiers in Oncology

doi 10.3389/fonc.2025.1529980

404 views

Perspective

Published on 18 Jun 2025

A spotlight on the MSc Cancer at UCL, 15 years on

in Cancer Molecular Targets and Therapeutics

Sarah Koushyar
John A. Hartley

Frontiers in Oncology

doi 10.3389/fonc.2025.1610068

417 views

Case Report

Accepted on 17 Jun 2025

Severe hypotension induced by Almonertinib: A case report with literature review and clinical insights

in Cancer Molecular Targets and Therapeutics

Haiyu Niu
Feixue Song
Xiaochun Zhou
Qiaoying Jin
Yating Liu
Benxin Luo
Hanwen Wei

Frontiers in Oncology

doi 10.3389/fonc.2025.1566768

119 views

Review

Accepted on 17 Jun 2025

MAPK -Targeted Therapies in Non-Gastro-Intestinal Stromal Tumors Soft Tissue Sarcoma: Current Landscape and Prospect

in Cancer Molecular Targets and Therapeutics

Ouissam Al Jarroudi
Khalid El Bairi
Sami Aziz Brahmi
said afqir

Frontiers in Oncology

doi 10.3389/fonc.2025.1418537

146 views

Original Research

Published on 17 Jun 2025

Design and immunogenic evaluation of multi-epitope vaccines for colorectal cancer: insights from molecular dynamics and In-Vitro studies

in Cancer Molecular Targets and Therapeutics

Peiwei Sun
Luolin Wang
Zhong Liu
Zhenglei Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1592072

501 views

Original Research

Published on 17 Jun 2025

A pan-cancer analysis of the prognostic and immunological roles of zinc finger protein 514 in human tumors

in Cancer Molecular Targets and Therapeutics

Shuai Zhao
Lin Cheng
Xingzhao Ji
Shengnan Sun
Yi Liu
Qiang Wan

Frontiers in Oncology

doi 10.3389/fonc.2025.1592989

341 views

Case Report

Accepted on 16 Jun 2025

Gefitinib in EGFR 19del recurrent aggressive fibromatosis

in Cancer Molecular Targets and Therapeutics

Jingjing Wu
Yanjing guo
Qianming Bai
Juefeng Wan
Qifeng Wang
Xinhong He
Xiaowei Zhang
Zhiguo Luo
Xin Liu
Liju Xing

Frontiers in Oncology

doi 10.3389/fonc.2025.1537714

Original Research

Accepted on 16 Jun 2025

Analysis of cancer-associated glycosyltransferases reveals novel targets of non-small cell lung cancer pathogenesis

in Cancer Molecular Targets and Therapeutics

Chang Liu
Thomas van Ee
Jurriaan Janssen
Ernesto Rodríguez
Yongsoo Kim
Teodora Radonic
Victor W van Beusechem
Marieke F. Fransen
Idris Bahce
Yvette van Kooyk

Frontiers in Oncology

doi 10.3389/fonc.2025.1601368

253 views