Frontiers in Oncology | Cancer Molecular Targets and Therapeutics

Original Research

Published on 09 Jan 2025

Deciphering the oncogenic network: how C1QTNF1-AS1 modulates osteosarcoma through miR-34a-5p and glycolytic pathways

in Cancer Molecular Targets and Therapeutics

Yu Zhang
Hailong Lun
Naiqiang Zhu
Ning Yang
Kaikai Ding
Bin Chen
Chengbing Chang
Haipeng Gu
Yanqi Liu

Frontiers in Oncology

doi 10.3389/fonc.2024.1485605

1,291 views

Review

Published on 09 Jan 2025

Key considerations based on pharmacokinetic/pharmacodynamic in the design of antibody-drug conjugates

in Cancer Molecular Targets and Therapeutics

Yangyang Gao
Yuwei Xia
Yixin Chen
Shiqi Zhou
Yingying Fang
Jieru Yu
Leyin Zhang
Leitao Sun

Frontiers in Oncology

doi 10.3389/fonc.2024.1459368

2,285 views

Original Research

Published on 07 Jan 2025

Machine learning-based identification of proteomic markers in colorectal cancer using UK Biobank data

in Cancer Molecular Targets and Therapeutics

Swarnima Kollampallath Radhakrishnan
Dipanwita Nath
Dominic Russ
Laura Bravo Merodio
Priyani Lad
Folakemi Kola Daisi
Animesh Acharjee

Frontiers in Oncology

doi 10.3389/fonc.2024.1505675

2,743 views
2 citations

Systematic review

Published on 07 Jan 2025

Efficacy and safety of nivolumab plus ipilimumab in gastrointestinal cancers: a systematic review and meta-analysis

in Cancer Molecular Targets and Therapeutics

Bowen Dai
Jiaping Jiang
Xiaoyu Yu
Haihua Zhan
Zhengchuan Hu

Frontiers in Oncology

doi 10.3389/fonc.2024.1515992

785 views

Review

Published on 07 Jan 2025

Advances and current concepts on Eph receptors and ephrins in upper digestive tract cancers

in Cancer Molecular Targets and Therapeutics

Luccas Lavareze
Talita de Carvalho Kimura
João Figueira Scarini
Reydson Alcides de Lima-Souza
Moisés Willian Aparecido Gonçalves
Raisa Sales de Sá
Iara Gonçalves Aquino
Patricia Maria Fernandes
Fernanda Cristina Poscai Ribeiro
Albina Altemani

Frontiers in Oncology

doi 10.3389/fonc.2024.1520306

794 views

Original Research

Published on 06 Jan 2025

Aurora kinase A promotes hepatic stellate cell activation and liver fibrosis through the Wnt/β-catenin pathway

in Cancer Molecular Targets and Therapeutics

Guanqi Dai
Junhao Lin
Yuchuan Jiang
Xinhui Liu
Peng Chen
Yixiao Zhang
Zhenghui Song
Xuefen Zhuang
Jinge Cong
Yingchun Li

Frontiers in Oncology

doi 10.3389/fonc.2024.1517226

968 views

Original Research

Published on 02 Jan 2025

Unveiling the role of ASPP1 in cancer progression: pan-cancer bioinformatics and experimental validation in colorectal cancer

in Cancer Molecular Targets and Therapeutics

Keyuan Xiao
Xiang Li
Ihsan Ullah
Wenqing Hu
Kaiqiang Wang
Fan Yang
Chengyu Yang
Chunqi Feng
Liang Zong
Xinghua Li

Frontiers in Oncology

doi 10.3389/fonc.2024.1529809

902 views

Original Research

Published on 24 Dec 2024

PGD2/PTGDR2 signaling pathway affects the self-renewal capacity of gastric cancer stem cells by regulating ATG4B ubiquitination

in Cancer Molecular Targets and Therapeutics

Qiang Zhang
HengJin Tian
Kunpeng Ge
FeiFan Wang
PeiYao Gao
AMin Chen
Lulu Wang
YanMing Zhao
Chaoqun Lian
FengChao Wang

Frontiers in Oncology

doi 10.3389/fonc.2024.1496050

706 views

Review

Published on 24 Dec 2024

Diagnostic and therapeutic role of non-coding RNAs regulating programmed cell death in melanoma

in Cancer Molecular Targets and Therapeutics

Zixu Wang
Cong Xie
Xiao Chen

Frontiers in Oncology

doi 10.3389/fonc.2024.1476684

1,383 views

Original Research

Published on 24 Dec 2024

The bioinformatics analysis and experimental validation of the carcinogenic role of EXO1 in lung adenocarcinoma

in Cancer Molecular Targets and Therapeutics

Bohao Sun
Jing Zhang
Nan Wang
Zhirong Zhang
Yichen Wu
Mengzhen Xie
Yanmei Peng
Yifan Ye
Zhaochang Jiang
Shumei Wei

Frontiers in Oncology

doi 10.3389/fonc.2024.1492725

1,126 views

Original Research

Published on 23 Dec 2024

Small-molecule MMRi36 induces apoptosis in p53-mutant lymphomas by targeting MDM2/MDM4/XIAP for degradation

in Cancer Molecular Targets and Therapeutics

Rati Lama
Wenjie Wu
Cory K. Mavis
Federico M. Ruiz
Javier Querol-García
Diana Martin
Sherry R. Chemler
Dhyan Chandra
David W. Goodrich
Francisco J. Hernandez-Ilizaliturri

Frontiers in Oncology

doi 10.3389/fonc.2024.1462231

774 views
1 citation

Original Research

Published on 20 Dec 2024

Serum NLR combined with CA125 and HE4 improves the diagnostic and prognostic efficiency in patients with ovarian cancer

in Cancer Molecular Targets and Therapeutics

Yun Tian
Xiabing Li
Hongjian Zhang
Yaping Wang
Hongyu Li
Qiaohong Qin

Frontiers in Oncology

doi 10.3389/fonc.2024.1494051

576 views

Systematic Review

Published on 20 Dec 2024

Bibliometric study on the utilization of sorafenib in hepatocellular carcinoma

in Cancer Molecular Targets and Therapeutics

Wenjun Meng
Yihang Luo
Lu Zhao
Yaoyu Zhang
Jiyan Liu
Shadan Li
Yang Du
Hongshuai Li

Frontiers in Oncology

doi 10.3389/fonc.2024.1507608

2,509 views

Case Report

Published on 17 Dec 2024

A good response to furmonertinib fourth-line treatment of an advanced lung adenocarcinoma patient with EGFR exon20in and PIK3CA mutation: a case report and literature review

in Cancer Molecular Targets and Therapeutics

Kai Sun
Peng Wang

Frontiers in Oncology

doi 10.3389/fonc.2024.1467722

1,529 views

Original Research

Published on 17 Dec 2024

Integration analysis of microRNAs as potential biomarkers in early-stage lung adenocarcinoma: the diagnostic and therapeutic significance of miR-183-3p

in Cancer Molecular Targets and Therapeutics

Guodong Huang
Yuxia Liu
Lisha Li
Bing Li
Ting Jiang
Yufeng Cao
Xiaoping Yang
Xinning Liu
Honglin Qu
Shitao Li

Frontiers in Oncology

doi 10.3389/fonc.2024.1508715

956 views

Review

Published on 16 Dec 2024

Unraveling IFI44L’s biofunction in human disease

in Cancer Molecular Targets and Therapeutics

Juan Du
Hui Luo
Shuang Ye
Hui Zhang
Zhen Zheng
Kaitai Liu

Frontiers in Oncology

doi 10.3389/fonc.2024.1436576

1,255 views
1 citation