Frontiers in Oncology | Gastrointestinal Cancers: Colorectal Cancer

Systematic Review

Published on 19 Feb 2026

Watch-and-Wait strategy for locally advanced rectal cancer after neoadjuvant chemoradiotherapy: a comprehensive review

in Gastrointestinal Cancers: Colorectal Cancer

Peng Huang
Xiaoyue Zhao
Huanhuan Fei
Linzhu Zhang
Xiaofan Liu
Yongjun Yu
Rong Wu
Fei Fei

Frontiers in Oncology

doi 10.3389/fonc.2026.1760042

658 views

Case Report

Published on 19 Feb 2026

A case report and literature review of duodenal adenocarcinoma with complete loss of mismatch repair proteins

in Gastrointestinal Cancers: Colorectal Cancer

Jie Ao
Xiangfeng Zhu
Yuan Zhao
Mimi Zhao
Yi Luo
Qiushi Wang

Frontiers in Oncology

doi 10.3389/fonc.2026.1749558

124 views

Original Research

Published on 18 Feb 2026

SpectraNet: a novel model for polyp segmentation leveraging a spectral-guided mixture of functional experts

in Gastrointestinal Cancers: Colorectal Cancer

Zhong Liu
Jing Ling

Frontiers in Oncology

doi 10.3389/fonc.2026.1734345

171 views

Original Research

Published on 18 Feb 2026

The relationship between perceived stress and depression in colorectal cancer patients: the mediating role of illness perception and the moderating role of self-efficacy

in Gastrointestinal Cancers: Colorectal Cancer

Fuzhuo Wang
Jiashuang Xu
Hong Sun
Xiuli Wang
Zhongguang Che
Ye Huang

Frontiers in Oncology

doi 10.3389/fonc.2026.1746202

Case Report

Accepted on 16 Feb 2026

Synchronous Primary High-Grade Appendiceal Mucinous Neoplasm (HAMN) and Ovarian Borderline Mucinous Cystadenoma: A Rare Case and Diagnostic Challenges

in Gastrointestinal Cancers: Colorectal Cancer

Yingyu Liu

Frontiers in Oncology

Original Research

Accepted on 16 Feb 2026

Dynamic monitoring of immunoglobulin G as a prognostic indicator after curative resection in high-risk stage II–III colorectal cancer: a retrospective cohort study

in Gastrointestinal Cancers: Colorectal Cancer

Junyi Sun
Feng Guo
Yinfang Guo
Ni Wang
Jiangxue Feng

Frontiers in Oncology

Original Research

Accepted on 16 Feb 2026

The potential of mitochondrial permeability transition-driven necrosis-related genes in prognostic evaluation of colorectal cancer patients

in Gastrointestinal Cancers: Colorectal Cancer

ChenXin Huang
DiYa Xie
BinSheng Lin
Kun Zhang

Frontiers in Oncology

Mini Review

Published on 11 Feb 2026

The enigma of squamous cell carcinoma of the colon: a case report and review

in Gastrointestinal Cancers: Colorectal Cancer

Eesha Oza
Yashvi Rateshwar
Areeba Nayyer
Steven Brower

Frontiers in Oncology

doi 10.3389/fonc.2026.1741167

656 views

Review

Published on 11 Feb 2026

Clinical trials of bispecific antibody therapy for colorectal cancer: advanced and next steps

in Gastrointestinal Cancers: Colorectal Cancer

Wen Shao
Yuhang Liu
Lina Huang
Sihan Lu
Yixiang Zhai
Yue Xiong
Nuojun Chen
Pengcheng Ye
Qijun Lv

Frontiers in Oncology

doi 10.3389/fonc.2026.1758251

924 views

Original Research

Published on 11 Feb 2026

Quality of life outcomes in colorectal cancer survivors: insights from an analytical study at a tertiary cancer center-Qatar

in Gastrointestinal Cancers: Colorectal Cancer

Nada Adli
Mohammed Adil Arbab Ahmed
Nahla AlMesbah
Nagah Selim
Mohamed Abdelsalam Elimam Ibrahim
Sujood Abdulwakeel Musa Awadelseed
Ihab Bougmiza
Hadi Mohamad Abu Rasheed
Kakil Rasul

Frontiers in Oncology

doi 10.3389/fonc.2025.1730212

558 views

Original Research

Accepted on 09 Feb 2026

Global, regional and national burden of colon and rectum cancer attributable to high fasting plasma glucose: a systematic analysis for the Global Burden of Disease Study 2021

in Gastrointestinal Cancers: Colorectal Cancer

Ke Lu
Gang Xu

Frontiers in Oncology

Systematic Review

Accepted on 09 Feb 2026

Tumor-Associated Neutrophils and Survival Outcomes in Colorectal Cancer: A Systematic Review and Multilevel Meta-Analysis

in Gastrointestinal Cancers: Colorectal Cancer

Ran Yang
Chongwei Zhu
Jinjin Zhao
Yun Tian

Frontiers in Oncology

Original Research

Accepted on 09 Feb 2026

An Interpretable Machine Learning Model for Predicting Distant Organ Metastasis After Radical Resection of Colorectal Cancer

in Gastrointestinal Cancers: Colorectal Cancer

Weibin Lin
Weixiang Ni
Junwei Zhou
Weixuan Hong
Junwei Fang
Meiping Wang
Chunhong Xiao
Guoliang Huang

Frontiers in Oncology

Original Research

Published on 09 Feb 2026

Deep learning radiomics models based on contrast-enhanced transrectal ultrasound for predicting distant metastasis in rectal cancer

in Gastrointestinal Cancers: Colorectal Cancer

Zhiyuan Xia
Lidan Liu
Haining Chen
Yanling Mo
Yefu Shen
Xihua Xie
Ming Qiu
Cun Liao
Huanyu Cui
Sen Zhang

Frontiers in Oncology

doi 10.3389/fonc.2026.1671887

452 views

Original Research

Published on 09 Feb 2026

Deep learning analysis of MRI to assess rectal cancer treatment

in Gastrointestinal Cancers: Colorectal Cancer

Heather M. Selby
Ashley Y. Son
Vipul R. Sheth
Todd H. Wagner
Erqi L. Pollom
Arden M. Morris

Frontiers in Oncology

doi 10.3389/fonc.2025.1643852

651 views

Original Research

Accepted on 06 Feb 2026

Identification of KRAS Mutation in Rectal Cancer Based on a 2.5D Deep Learning Model

in Gastrointestinal Cancers: Colorectal Cancer

Chengmeng Zhang
Jinge Li
peng Chen
Yanyan Zhou
Jian Shen
Guanfeng Chen

Frontiers in Oncology

101 views

Original Research

Published on 05 Feb 2026

Long-term oncological outcomes of laparoscopic versus transanal total mesorectal excision for mid-low rectal cancer: a propensity score matching analysis

in Gastrointestinal Cancers: Colorectal Cancer

Yang Xie
Ziwei Wang
Hongyu Zhang

Frontiers in Oncology

doi 10.3389/fonc.2026.1715774

564 views

Original Research

Published on 05 Feb 2026

Health-related quality of life scores of ultralow rectal cancer patients after conformal sphincter preservation operation compared to newly derived preoperative EORTC QLQ-C30, CR38 reference values and EORTC QLQ-C30 norm

in Gastrointestinal Cancers: Colorectal Cancer

Hai‐bo Ding
Ge Sun
Guan‐yu Yu
Xian‐hua Gao
Zheng Lou
Zheng Kuo
Hai‐feng Gong
Xiao‐ming Zhu
Wei Zhang

Frontiers in Oncology

doi 10.3389/fonc.2026.1724255

406 views

Systematic Review

Published on 05 Feb 2026

Prognostic value of systemic immune-inflammation index for colorectal cancer: a systematic review and meta-analysis

in Gastrointestinal Cancers: Colorectal Cancer

Pengfei Wang
Huiying Jiang

Frontiers in Oncology

doi 10.3389/fonc.2026.1616016

561 views

Original Research

Accepted on 03 Feb 2026

Association Between Pre-Reversal Systemic Inflammation Response Index and Low Anterior Resection Syndrome in Rectal Cancer Patients: A Retrospective Cohort Study

in Gastrointestinal Cancers: Colorectal Cancer

Xuena Zhang
Meng Qingyu
Jingru Wang
Simeng Jiang
Zhongtao Tian
Zihan Fan
Tong Wang
Wenbo Niu

Frontiers in Oncology

Case Report

Published on 03 Feb 2026

Submucosal metastatic leiomyosarcoma of the colon presenting with intussusception and lower gastrointestinal bleeding: a case report

in Gastrointestinal Cancers: Colorectal Cancer

Honghai Li
Zunfang Yu
Minfeng Ye
Qijing Jin

Frontiers in Oncology

doi 10.3389/fonc.2026.1748739

427 views

Perspective

Published on 03 Feb 2026

Colorectal cancer as a complex adaptive system: integrating the hallmarks of cancer with complexity theory

in Gastrointestinal Cancers: Colorectal Cancer

Luis R. Basbus

Frontiers in Oncology

doi 10.3389/fonc.2025.1736140

641 views

Original Research

Accepted on 02 Feb 2026

Explore the efficacy of microwave ablation combined with 1 fruquintinib and tislelizumab in the treatment of metastatic 2 colorectal cancer

in Gastrointestinal Cancers: Colorectal Cancer

Wei Qian
Huatang zhang
Yanhua Mo
Chaoyang Wu
Juntong Liu
Yuyi Pen
Cantu Fang
Jincheng Meng

Frontiers in Oncology

Systematic Review

Published on 02 Feb 2026

Efficacy and safety of 3-month versus 6-month oxaliplatin-based adjuvant chemotherapy in colorectal cancer: a systematic review and meta-analysis

in Gastrointestinal Cancers: Colorectal Cancer

Haiqiong Wu
Jun Li
Jidong Miao
Jiawei Li

Frontiers in Oncology

doi 10.3389/fonc.2026.1762273

622 views

987 articles

articles

Watch-and-Wait strategy for locally advanced rectal cancer after neoadjuvant chemoradiotherapy: a comprehensive review

A case report and literature review of duodenal adenocarcinoma with complete loss of mismatch repair proteins

SpectraNet: a novel model for polyp segmentation leveraging a spectral-guided mixture of functional experts

The relationship between perceived stress and depression in colorectal cancer patients: the mediating role of illness perception and the moderating role of self-efficacy

Synchronous Primary High-Grade Appendiceal Mucinous Neoplasm (HAMN) and Ovarian Borderline Mucinous Cystadenoma: A Rare Case and Diagnostic Challenges

Dynamic monitoring of immunoglobulin G as a prognostic indicator after curative resection in high-risk stage II–III colorectal cancer: a retrospective cohort study

The potential of mitochondrial permeability transition-driven necrosis-related genes in prognostic evaluation of colorectal cancer patients

The enigma of squamous cell carcinoma of the colon: a case report and review

Clinical trials of bispecific antibody therapy for colorectal cancer: advanced and next steps

Quality of life outcomes in colorectal cancer survivors: insights from an analytical study at a tertiary cancer center-Qatar

Global, regional and national burden of colon and rectum cancer attributable to high fasting plasma glucose: a systematic analysis for the Global Burden of Disease Study 2021

Tumor-Associated Neutrophils and Survival Outcomes in Colorectal Cancer: A Systematic Review and Multilevel Meta-Analysis

An Interpretable Machine Learning Model for Predicting Distant Organ Metastasis After Radical Resection of Colorectal Cancer

Deep learning radiomics models based on contrast-enhanced transrectal ultrasound for predicting distant metastasis in rectal cancer

Deep learning analysis of MRI to assess rectal cancer treatment

Identification of KRAS Mutation in Rectal Cancer Based on a 2.5D Deep Learning Model

Long-term oncological outcomes of laparoscopic versus transanal total mesorectal excision for mid-low rectal cancer: a propensity score matching analysis

Health-related quality of life scores of ultralow rectal cancer patients after conformal sphincter preservation operation compared to newly derived preoperative EORTC QLQ-C30, CR38 reference values and EORTC QLQ-C30 norm

Prognostic value of systemic immune-inflammation index for colorectal cancer: a systematic review and meta-analysis

Association Between Pre-Reversal Systemic Inflammation Response Index and Low Anterior Resection Syndrome in Rectal Cancer Patients: A Retrospective Cohort Study

Submucosal metastatic leiomyosarcoma of the colon presenting with intussusception and lower gastrointestinal bleeding: a case report

Colorectal cancer as a complex adaptive system: integrating the hallmarks of cancer with complexity theory

Explore the efficacy of microwave ablation combined with 1 fruquintinib and tislelizumab in the treatment of metastatic 2 colorectal cancer

Efficacy and safety of 3-month versus 6-month oxaliplatin-based adjuvant chemotherapy in colorectal cancer: a systematic review and meta-analysis