Frontiers in Oncology | Gastrointestinal Cancers: Colorectal Cancer

Original Research

Published on 04 Jul 2025

Bioinformatics and experimental unveiling of TIMP1 as a novel therapeutic target in colorectal cancer ferroptosis

in Gastrointestinal Cancers: Colorectal Cancer

Chao Tang
Zhenhan Li
Tianyu Song
Linming Lu
Bofeng Chen
Tao Zhang
Yi Zhang
Jie Yang
Jianle Lao
Hao Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1593107

496 views

Original Research

Published on 04 Jul 2025

The effectiveness of the hemoglobin, albumin, lymphocyte, and platelet (HALP) score in predicting lymph node metastasis in radiologically n0 locally advanced upper rectal cancer

in Gastrointestinal Cancers: Colorectal Cancer

Osman Bardakçı
Gökay Çetinkaya

Frontiers in Oncology

doi 10.3389/fonc.2025.1579581

281 views

Review

Published on 04 Jul 2025

A review of circular RNAs in colorectal cancer: insights into biomarker discovery and therapeutic targeting

in Gastrointestinal Cancers: Colorectal Cancer

Sibin Nambidi
Karunakaran Bhuvaneswari Shruthi
Sujatha Padmanaban Kanimozhe
Antara Banerjee
Suresh Babu Kondaveeti
Asim K. Duttaroy
Surajit Pathak

Frontiers in Oncology

doi 10.3389/fonc.2025.1549046

361 views

Original Research

Published on 04 Jul 2025

Association between genomic features and toxic metal(loid) accumulation in left-sided and right-sided colorectal cancer

in Gastrointestinal Cancers: Colorectal Cancer

Shoujiang Yu
Min Fu
Yurong Wang
Ling Lin
Shushen Ji
Feng Du
Li Song
Mengzhu Wang
Yufeng Zhai
Jiangman Zhao

Frontiers in Oncology

doi 10.3389/fonc.2025.1584424

283 views

Original Research

Published on 02 Jul 2025

Efficacy of opioid-free anesthesia in short-term recovery following laparoscopic-assisted colorectal tumor resection: a randomized trial

in Gastrointestinal Cancers: Colorectal Cancer

Liang Zhang
Xian-Hua Yu
Hui-Ming Zhang
Sheng Wang
Jian-Long Chen
Xue-Shan Li
Zhi-Yuan Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1588623

326 views

Original Research

Accepted on 30 Jun 2025

Clinical Impact of First-Line Therapeutic Strategies in BRAF V600E-Mutant Metastatic Colorectal Cancer: Real-World Evidence and Prognostic Insight

in Gastrointestinal Cancers: Colorectal Cancer

CHIA CHANG YEH
SHIH WEI CHIANG
Feng Fen Chiang

Frontiers in Oncology

doi 10.3389/fonc.2025.1608538

149 views

Original Research

Accepted on 30 Jun 2025

Population-Based Colorectal Cancer Risk Prediction Using a SHAP-Enhanced LightGBM Model

in Gastrointestinal Cancers: Colorectal Cancer

Guinian Du
Hui Lv
Yishan Liang
Jingyue Zhang
Qiaoling Huang
Guiming Xie
Xian Wu
Hao Zeng
Lijuan Wu
Jianbo Ye

Frontiers in Oncology

doi 10.3389/fonc.2025.1575844

150 views

Original Research

Accepted on 30 Jun 2025

Genetic variants and clinical determinants affecting the response to 5-Fluorouracil-based treatment in Chilean patients with advanced colorectal cancer

in Gastrointestinal Cancers: Colorectal Cancer

Leslie Carol Cerpa
Christopher Sandoval
Paula Escalante
Juan Pablo Cayun Pellizaris
Maria Alejandra Lavanderos
Claudio Alarcón-Concha
Guillermo Kaempfe
Diego Moreno-Tapia
Camilo Salvador Quiroz
Carolina Gutierrez-Cáceres

Frontiers in Oncology

doi 10.3389/fonc.2025.1589724

Original Research

Accepted on 30 Jun 2025

MicroRNAs in Circulating Extracellular Vesicles as Biomarkers of Early Colorectal Cancer Captured using High Mannose N-glycanspecific Lectin from Oscillatoria Agardhii

in Gastrointestinal Cancers: Colorectal Cancer

Sanae Nakayama
Miyabi Umeda
Kenya Kobayashi
Yukiko Nakano
Kanji Hori
Tsukuru Umemura
Hiroshi Kurokawa

Frontiers in Oncology

doi 10.3389/fonc.2025.1619460

General Commentary

Accepted on 30 Jun 2025

Commentary: Efficacy and safety of massage for postoperative stress in colorectal cancer patients: a randomized, controlled, three-arm trial

in Gastrointestinal Cancers: Colorectal Cancer

Yingjie Liu
Keying Wang
Wenjiang Wu

Frontiers in Oncology

doi 10.3389/fonc.2025.1626131

Original Research

Accepted on 30 Jun 2025

Description and Disposition of Home Patients with Colorectal Cancer Accessing a practical, complications related Medication Therapy Management Service

in Gastrointestinal Cancers: Colorectal Cancer

Qinbo Wang
Yuan Zhou
Hua Li
Yingjuan Ou
Jiaxi Fei
Xia Wu
Junrong Chen
Xiaoyan Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1595010

Original Research

Published on 30 Jun 2025

Analysis of the molecular subtypes and prognostic models of anoikis-related genes in colorectal cancer

in Gastrointestinal Cancers: Colorectal Cancer

Lei Shen
Kang Hou
Jifeng Zhang
Xiaodong Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1579843

336 views

Systematic Review

Published on 27 Jun 2025

Comparative outcomes of combined thermal ablation and liver resection versus liver resection alone for multiple colorectal liver metastases: a systematic review and meta-analysis

in Gastrointestinal Cancers: Colorectal Cancer

Zesong Meng
Baokun Li
Chaoxi Zhou
Longfei Cao
Jianfeng Zhang
Jun Feng
Guiying Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1613615

414 views

Original Research

Published on 27 Jun 2025

Renal dysfunction as a predictor of recurrence and prognosis in colorectal cancer

in Gastrointestinal Cancers: Colorectal Cancer

Xuekang Ren
Shaogong Zhu
Rongzhen Li
Yunzhan Xia

Frontiers in Oncology

doi 10.3389/fonc.2025.1606286

300 views

Review

Accepted on 26 Jun 2025

Advances in Extracellular Vesicle (EV) Biomarkers for Precision Diagnosis and Therapeutic in Colorectal Cancer

in Gastrointestinal Cancers: Colorectal Cancer

Li Zhang
Hui Shen
Nenghua Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1581015

Original Research

Accepted on 26 Jun 2025

Predictive value of serum miR-21 and miR-122 expression on the efficacy of capecitabine combined with transcatheter hepatic arterial embolization chemotherapy for liver metastasis after colorectal cancer surgery in patients with colorectal cancer and construction and verification of nomograms

in Gastrointestinal Cancers: Colorectal Cancer

Wenfang Ma
Zukuan Chang
Shixing Li
Xiuhua Wang
Guangshao Cao
Youjie Fan

Frontiers in Oncology

doi 10.3389/fonc.2025.1604994