Frontiers in Oncology | Gastrointestinal Cancers: Colorectal Cancer

Original Research

Published on 17 Dec 2025

Trends and disparities in the US colorectal cancer mortality, 1999–2023: an analysis of the CDC WONDER database

in Gastrointestinal Cancers: Colorectal Cancer

Yingkai Feng
Xinyu Fa
Jianping Liu
Hong Qi

Frontiers in Oncology

doi 10.3389/fonc.2025.1693240

600 views

General Commentary

Published on 17 Dec 2025

Commentary: Low expression of SOD and PRX4 as indicators of poor prognosis and systemic inflammation in colorectal cancer

in Gastrointestinal Cancers: Colorectal Cancer

Yan Zhang
Xiao Dong
Na Liu
Yonghong Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1739574

376 views

Correction

Published on 17 Dec 2025

Correction: Multiomics analyses of human colorectal cancer reveal changes in mitochondrial metabolism associated with chemotherapy resistance

in Gastrointestinal Cancers: Colorectal Cancer

Shiyi Chen
Qian Li
Wei Zheng

Frontiers in Oncology

doi 10.3389/fonc.2025.1756306

306 views

Original Research

Published on 17 Dec 2025

A large-scale study integrating CEA and tumor deposits to evaluate prognosis in colon cancer patients

in Gastrointestinal Cancers: Colorectal Cancer

Ya’nan Fan
Yun Sun
Xiaojie Hu
Lifei Zhang
Jiantao Dong
Fei Liu
Zhiqiang Wang
Jianhui Cai

Frontiers in Oncology

doi 10.3389/fonc.2025.1626538

619 views

Systematic Review

Accepted on 16 Dec 2025

Efficacy and Safety of Traditional Chinese Medicine as an Adjuvant to Postoperative Chemotherapy in Colorectal Cancer: A Meta-Analysis

in Gastrointestinal Cancers: Colorectal Cancer

Qinsi He
Xiaodan Chen
Haotian Zeng
Xinyu Gao
Zhi Zheng
Jun Rao
Qun Wen
Xuchao Yu
Jiquan Zeng

Frontiers in Oncology

193 views

Systematic Review

Accepted on 16 Dec 2025

Association between cholecystectomy/gallbladder pathology and colorectal polyps: a systematic review and meta-analysis

in Gastrointestinal Cancers: Colorectal Cancer

Shirui Li
Yunfan Deng
Sheng Dai
Qi Fan
Dehai Xiong
Xiuyang Li

Frontiers in Oncology

118 views

Original Research

Published on 16 Dec 2025

Global burden of colorectal cancer from 1990 to 2021: a systematic analysis from the Global Burden of Disease Study 2021

in Gastrointestinal Cancers: Colorectal Cancer

Xue Chen
Rui Tian
Ze Chen
Longfang Quan
Shaosheng Bei

Frontiers in Oncology

doi 10.3389/fonc.2025.1676855

610 views

Original Research

Accepted on 15 Dec 2025

Analysis of Risk Factors for prolonged Intensive Care Unit Stay After Colorectal Cancer Surgery

in Gastrointestinal Cancers: Colorectal Cancer

Xuefeng Song
Yabin Liu
Biao Dong

Frontiers in Oncology

Case Report

Published on 15 Dec 2025

Case Report: Biweekly TAS-102 and bevacizumab as maintenance therapy for recurrent and metastatic pseudomyxoma peritonei following palliative cytoreduction

in Gastrointestinal Cancers: Colorectal Cancer

Baoxuan Wang
Yan Wang
Dong Zhao
Houjun Zhang
Qi Liu
Guanying Yu
Jie Jiao

Frontiers in Oncology

doi 10.3389/fonc.2025.1631286

572 views

Original Research

Published on 15 Dec 2025

Poor nutritional status based on controlling nutritional status score and nutritional risk index may be related to the occurrence of complications after laparoscopic treatment in patients with gastrointestinal tumors aged no more than 60 years

in Gastrointestinal Cancers: Colorectal Cancer

Xueyong Deng
Zhiwang Li
Lv Ye
Chengkun Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1723703

367 views

Correction

Published on 15 Dec 2025

Correction: Construction of a prognostic model for colorectal cancer liver metastasis based on single-cell transcriptomics and regulation of the MIF pathway

in Gastrointestinal Cancers: Colorectal Cancer

Jianqiang Cao
Zhaobin He
HuiJie Gao
Yongzhe Yu
Shengbiao Yang
Xiqiang Wang
Jun Niu
Cheng Peng

Frontiers in Oncology

doi 10.3389/fonc.2025.1731870

305 views

Original Research

Accepted on 12 Dec 2025

Construction of a prognostic survival model for colorectal cancer patients using CT image texture analysis: a prospective cohort study

in Gastrointestinal Cancers: Colorectal Cancer

Chen-hua Sun
Hao-di Wang
Wen-hao Sun
Guanwen Gong
Zheng-ming Deng
Zhi-wei Jiang

Frontiers in Oncology

209 views

Original Research

Accepted on 11 Dec 2025

Unveiling the Prognostic Role of FABP4 in Early-Onset Colorectal Cancer through Big Data Analysis and Preliminary Clinical Validation

in Gastrointestinal Cancers: Colorectal Cancer

Yu Wu
Weiwei Zou
Shengjun Zhang
Lipeng Zhao
Shaohua He
Fan Yao
Peilin Qing
Yixin Li
Jie Li
Xiao-Liang Xing

Frontiers in Oncology

175 views

Original Research

Accepted on 11 Dec 2025

Oophorectomy followed by postoperative chemotherapy for ovarian metastasis of colorectal cancer: a retrospective analysis

in Gastrointestinal Cancers: Colorectal Cancer

YuHua Zhang
Guangyue Zhao
Yun Qiao
Yongchao Ba
Ye Tian
Xing Song
Ning Guan
Xiaoqian Hou
Yan Zhang

Frontiers in Oncology

232 views

Systematic Review

Published on 10 Dec 2025

Cancer-associated fibroblasts and their prognostic role in colorectal cancer: review and meta-analysis

in Gastrointestinal Cancers: Colorectal Cancer

Silvia Mihaela Ilie
Laurentia Gales
Ana Maria Musina
Kevin Rouet
Alexandra Elena Stefan
Mara Simona Belceanu
Anda Stefania Trandafir
Constantin Guillaume
Aurélie Bertaut
Ikram Charifi

Frontiers in Oncology

doi 10.3389/fonc.2025.1635055

753 views

Original Research

Published on 09 Dec 2025

Citywide community-based colorectal cancer screening in urban Shanghai: age and sex variations in risk mitigation from 1973 to 2020

in Gastrointestinal Cancers: Colorectal Cancer

Mengyin Wu
Yangming Gong
Chunxiao Wu
Peng Peng
Lei Chen
Qi Li
Liang Shi
Yongmei Xiang
Jianming Dou
Yi Pang

Frontiers in Oncology

doi 10.3389/fonc.2025.1707133

461 views

Review

Accepted on 08 Dec 2025

Research Progress on Early Diagnostic Biomarkers and Liquid Biopsy Technologies for Colorectal Cancer: A Comprehensive Review

in Gastrointestinal Cancers: Colorectal Cancer

He Shen
Zhonghao Wang
Wenjin Zhang

Frontiers in Oncology

212 views

Original Research

Accepted on 08 Dec 2025

Diagnostic Value of Multi-Gene Methylation in Colorectal Cancer Screening

in Gastrointestinal Cancers: Colorectal Cancer

Qingyan Yang
Liming Chen

Frontiers in Oncology

154 views

Original Research

Published on 08 Dec 2025

DDX49 as a novel prognostic biomarker regulates colorectal cancer cell proliferation through the TIMM44-PI3K-AKT pathway

in Gastrointestinal Cancers: Colorectal Cancer

Baoyu Huang
Zhipeng Yin
Gang Gao
Longhai Li
Miao Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1707092

475 views

Original Research

Published on 05 Dec 2025

Emodin inhibits colon cancer tumor growth by suppressing tumor cell glycolysis through inhibition of NAT10-mediated PGK1 ac4C modification

in Gastrointestinal Cancers: Colorectal Cancer

Zhuoxin Wei
Zhuo Lv
Weimin Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1575391

718 views

Case Report

Published on 03 Dec 2025

Case Report: T-Dxd plus bevacizumab in a patient with brain metastases from rectal cancer with HER2 amplification

in Gastrointestinal Cancers: Colorectal Cancer

Yanan Jia
Xueqin Li
Huisheng Chen
Lisha Wu
Yinduo Zeng
Tao Qin

Frontiers in Oncology

doi 10.3389/fonc.2025.1714422

734 views

Review

Published on 03 Dec 2025

Neoadjuvant therapy for pMMR/MSS locally advanced rectal cancer in the immunotherapy era: current landscape and future perspectives

in Gastrointestinal Cancers: Colorectal Cancer

Benish Farooq
Xingyu Li
Sa Xiao
Xiaojun Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1719642

1,182 views

Review

Published on 03 Dec 2025

Microbiota-host metabolism reprogramming in colorectal cancer: from pathogenesis to precision therapies

in Gastrointestinal Cancers: Colorectal Cancer

Chengxu Guo
Caixia Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1713614

812 views

Mini Review

Published on 28 Nov 2025

Advances in colorectal cancer screening: technological innovations, guideline discrepancies, and individualized strategies

in Gastrointestinal Cancers: Colorectal Cancer

Li Tang
Xiaoyong Zhao
Guohong Wang
Jiehao Huang
Mu Zhang
Wei Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1723546

1,121 views

962 articles

articles

Trends and disparities in the US colorectal cancer mortality, 1999–2023: an analysis of the CDC WONDER database

Commentary: Low expression of SOD and PRX4 as indicators of poor prognosis and systemic inflammation in colorectal cancer

Correction: Multiomics analyses of human colorectal cancer reveal changes in mitochondrial metabolism associated with chemotherapy resistance

A large-scale study integrating CEA and tumor deposits to evaluate prognosis in colon cancer patients

Efficacy and Safety of Traditional Chinese Medicine as an Adjuvant to Postoperative Chemotherapy in Colorectal Cancer: A Meta-Analysis

Association between cholecystectomy/gallbladder pathology and colorectal polyps: a systematic review and meta-analysis

Global burden of colorectal cancer from 1990 to 2021: a systematic analysis from the Global Burden of Disease Study 2021

Analysis of Risk Factors for prolonged Intensive Care Unit Stay After Colorectal Cancer Surgery

Case Report: Biweekly TAS-102 and bevacizumab as maintenance therapy for recurrent and metastatic pseudomyxoma peritonei following palliative cytoreduction

Poor nutritional status based on controlling nutritional status score and nutritional risk index may be related to the occurrence of complications after laparoscopic treatment in patients with gastrointestinal tumors aged no more than 60 years

Correction: Construction of a prognostic model for colorectal cancer liver metastasis based on single-cell transcriptomics and regulation of the MIF pathway

Construction of a prognostic survival model for colorectal cancer patients using CT image texture analysis: a prospective cohort study

Unveiling the Prognostic Role of FABP4 in Early-Onset Colorectal Cancer through Big Data Analysis and Preliminary Clinical Validation

Oophorectomy followed by postoperative chemotherapy for ovarian metastasis of colorectal cancer: a retrospective analysis

Cancer-associated fibroblasts and their prognostic role in colorectal cancer: review and meta-analysis

Citywide community-based colorectal cancer screening in urban Shanghai: age and sex variations in risk mitigation from 1973 to 2020

Research Progress on Early Diagnostic Biomarkers and Liquid Biopsy Technologies for Colorectal Cancer: A Comprehensive Review

Diagnostic Value of Multi-Gene Methylation in Colorectal Cancer Screening

DDX49 as a novel prognostic biomarker regulates colorectal cancer cell proliferation through the TIMM44-PI3K-AKT pathway

Emodin inhibits colon cancer tumor growth by suppressing tumor cell glycolysis through inhibition of NAT10-mediated PGK1 ac4C modification

Case Report: T-Dxd plus bevacizumab in a patient with brain metastases from rectal cancer with HER2 amplification

Neoadjuvant therapy for pMMR/MSS locally advanced rectal cancer in the immunotherapy era: current landscape and future perspectives

Microbiota-host metabolism reprogramming in colorectal cancer: from pathogenesis to precision therapies

Advances in colorectal cancer screening: technological innovations, guideline discrepancies, and individualized strategies