Frontiers in Oncology | Gastrointestinal Cancers: Colorectal Cancer

Case Report

Published on 12 Jun 2025

Case Report: Metastatic small bowel adenocarcinoma with DNA mismatch repair deficiency in an organ transplant recipient treated with anti-PD-1 immunotherapy

in Gastrointestinal Cancers: Colorectal Cancer

Quan H. Phung
Alexander K. Tsai
Byoung U. Park
Robben Schat
Richard Spong
L. Jill Tsai
Amit A. Kulkarni
Emmanuel S. Antonarakis
Arjun Gupta

Frontiers in Oncology

doi 10.3389/fonc.2025.1579364

847 views

Original Research

Published on 12 Jun 2025

Navigating beyond the surface - prognostic significance of KRAS, NRAS, BRAF, PIK3CA, and TP53 mutations examined by exons

in Gastrointestinal Cancers: Colorectal Cancer

Vlad Adrian Afrăsânie
Mihai Vasile Marinca
Bogdan Gafton
Alexandra Rusu
Eliza Maria Froicu
Daniel Sur
Cristian Virgil Lungulescu
Raluca Cezara Popa
Irina Afrăsânie
Anca Viorica Ivanov

Frontiers in Oncology

doi 10.3389/fonc.2025.1557609

827 views

Systematic Review

Published on 12 Jun 2025

The efficacy and safety of chemoimmunotherapy in patients with MSI-L/MSS/pMMR status metastatic colorectal cancer: a systematic review and meta-analysis of randomized controlled trials

in Gastrointestinal Cancers: Colorectal Cancer

Qi-Jing Zhang
Jia-xin Zhou
Da-hai Hu
Jing-hua Pan
Si-min Luo
Qi Yao

Frontiers in Oncology

doi 10.3389/fonc.2025.1514485

880 views

Original Research

Published on 11 Jun 2025

Real-world treatment patterns and outcomes among patients initiating sequential regorafenib and trifluridine/tipiracil ± bevacizumab in patients with metastatic colorectal cancer in a US community setting (SEQRT2)

in Gastrointestinal Cancers: Colorectal Cancer

Tanios Bekaii-Saab
Ila Sruti
Junxin Shi
Wei Dai
Gregory Patton
Sreevalsa Appukkuttan
Brian Hocum
Arvind Katta
Svetlana Babajanyan
David Cosgrove

Frontiers in Oncology

doi 10.3389/fonc.2025.1591245

1,133 views

Original Research

Published on 09 Jun 2025

Adoptive cellular immunotherapy combined with chemotherapy versus chemotherapy alone in Chinese patients with metastatic colorectal cancer: a cost-effectiveness analysis to inform drug pricing

in Gastrointestinal Cancers: Colorectal Cancer

Liman Huo
Ping Liang
Yangyang Duan
Yanmei Xu
Jianhua Tang
Qi Lv
Rui Feng

Frontiers in Oncology

doi 10.3389/fonc.2025.1590319

1,087 views

Original Research

Published on 09 Jun 2025

A multivariate model of IVIM-DWI in the preoperative diagnosis of tumor budding grade in rectal cancer

in Gastrointestinal Cancers: Colorectal Cancer

Junyi Fu
Chenglong Zhao
Guangying Zheng
Aiyin Li
Gesheng Song

Frontiers in Oncology

doi 10.3389/fonc.2025.1543607

770 views

Original Research

Published on 06 Jun 2025

Real-world analysis of community colorectal neoplasia screening based on stool DNA methylation detection

in Gastrointestinal Cancers: Colorectal Cancer

Ming-sheng Fu
Shu-xian Pan
Xun-quan Cai
Ya-wen Cao
Li-yuan Jin
Qin-cong Pan

Frontiers in Oncology

doi 10.3389/fonc.2025.1562698

776 views

Original Research

Published on 05 Jun 2025

A predictive model to identify optimal candidates for surgery among patients with metastatic colorectal cancer

in Gastrointestinal Cancers: Colorectal Cancer

Xiqiang Zhang
Zhaoyi Jing
Longchao Wu
Ze Tao
Dandan Lu

Frontiers in Oncology

doi 10.3389/fonc.2025.1573431

891 views

Original Research

Published on 05 Jun 2025

Comparison of clinicopathological characteristics and survival outcomes between solitary and multiple rectal neuroendocrine tumors: a propensity score-matched study

in Gastrointestinal Cancers: Colorectal Cancer

Ye Zheng
Limei Wang
Jing Guo
Peng Wang
Rui Ji
Jun Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1599022

646 views

Original Research

Published on 05 Jun 2025

GPD1L downregulation in colorectal cancer: a novel obesity-related biomarker linking metabolic dysregulation to tumor progression

in Gastrointestinal Cancers: Colorectal Cancer

Feng Zhu
Huiyuan Li
Hongzhang Liu
Yusheng Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1582728

961 views

Original Research

Published on 30 May 2025

Pathologic complete response after neoadjuvant therapy for locally advanced rectal cancer in a real-world setting: a population-based study

in Gastrointestinal Cancers: Colorectal Cancer

Lina Cadili
Jonathan M. Loree
Michael Peacock
Kimberly DeVries
Amandeep Ghuman
Ahmer A. Karimuddin
P. Terry Phang
Manoj J. Raval
Carl J. Brown

Frontiers in Oncology

doi 10.3389/fonc.2025.1573819

859 views

Original Research

Published on 30 May 2025

Postoperative adjuvant chemotherapy in patients with stage II early onset colorectal cancer: exploration and discovery using real-world data and the SEER database

in Gastrointestinal Cancers: Colorectal Cancer

Shikun Cao
Yihuan Qiao
Lijun Wu
Qi Chen
Kai Tian
Jipeng Li
Chungen Xing

Frontiers in Oncology

doi 10.3389/fonc.2025.1566569

645 views

Case Report

Published on 30 May 2025

Simultaneous double primary malignant tumors of MSS/pMMR ascending colon cancer and MSI-H/dMMR duodenal cancer with nearly 2 years of recurrence-free survival after MDT-guided comprehensive treatment: a case report

in Gastrointestinal Cancers: Colorectal Cancer

Weimin Wang
Quan Yang
Yifan He
Xuefeng Cha
Chaoxian Xiong
Xiaoxia Li
Jie Li
Pin Gao
Kun Yu

Frontiers in Oncology

doi 10.3389/fonc.2025.1573580

747 views

Review

Published on 30 May 2025

Role of diet, physical activity and new drugs in the primary management of cancer cachexia in gastrointestinal tumors – a comprehensive review

in Gastrointestinal Cancers: Colorectal Cancer

Ester Oneda
Alessandra Manno
Silvia Noventa
Michela Libertini
Sara Cherri
Alberto Zaniboni

Frontiers in Oncology

doi 10.3389/fonc.2025.1600425

913 views

Original Research

Published on 30 May 2025

Enhanced diagnostic precision of colorectal sessile lesions with blue laser imaging and JNET classification: a multicenter retrospective study in Chinese cohorts

in Gastrointestinal Cancers: Colorectal Cancer

Feng Wu
Wenxin Tan
Panpan Liu
Weiguang Qiao
Tongyin Xing

Frontiers in Oncology

doi 10.3389/fonc.2025.1534922

626 views

Brief Research Report

Published on 19 May 2025

Global disease burden of colorectal cancer attributable to high BMI has more than doubled over the past 30 years

in Gastrointestinal Cancers: Colorectal Cancer

Jiamin Zeng
Wenjie Li
Zhiming Wu

Frontiers in Oncology

doi 10.3389/fonc.2025.1580458

790 views