Frontiers in Oncology | Gastrointestinal Cancers: Colorectal Cancer

Original Research

Published on 25 Nov 2025

The role of TMEM59L in colorectal cancer progression and its interaction with the TGF-β/Smad pathway

in Gastrointestinal Cancers: Colorectal Cancer

Hongjie Yang
Jiafei Liu
Peishi Jiang
Yi Sun
Lingyi Chen
Siwei Zhu

Frontiers in Oncology

doi 10.3389/fonc.2025.1674849

797 views

Case Report

Published on 24 Nov 2025

Complete remission of advanced MSI-H rectal cancer in a young patient treated with nivolumab: a case report and critical appraisal of the literature

in Gastrointestinal Cancers: Colorectal Cancer

Marian Liberko
Renata Soumarova

Frontiers in Oncology

doi 10.3389/fonc.2025.1680308

906 views

Original Research

Published on 24 Nov 2025

Global, regional and national burden of colorectal cancer and its risk factors, 1990–2021: a systematic analysis for the GBD 2021

in Gastrointestinal Cancers: Colorectal Cancer

Xuan Zeng
Jibo Wang
Ning Liu
Long Chen
Liang Liang
Li Zhuo
Xiaoyong Zhang
Mao Lin

Frontiers in Oncology

doi 10.3389/fonc.2025.1673341

1,019 views

Case Report

Accepted on 21 Nov 2025

Neoadjuvant Therapy with Cadonilimab in a Patient with MSI-H/dMMR Colorectal Cancer: A Case Report

in Gastrointestinal Cancers: Colorectal Cancer

Jingrui Zhou
Tao Shen
Weimin Chen
Jue Wang
Chen Ziwei
Guanghui Guo
Yuchun Zhuang

Frontiers in Oncology

174 views

Original Research

Accepted on 18 Nov 2025

Deep Learning Analysis of MRI to assess Rectal Cancer Treatment

in Gastrointestinal Cancers: Colorectal Cancer

Heather M. Selby
Yewon A. Son
Vipul R. Sheth
Todd Wagner
Erqi Pollom
Arden M. Morris

Frontiers in Oncology

175 views

Case Report

Published on 17 Nov 2025

Reconstruction of a massive abdominal wall defect after colon cancer surgery using bilateral thoracoabdominal flaps and a vertical rectus abdominis myocutaneous flap: a case report

in Gastrointestinal Cancers: Colorectal Cancer

Shuo Li
Zhi Zhang
Chongqing Gao
Tao Wang
Zhen Zhang
Zikang Wang
Guixiang Zhang
Gangcheng Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1698546

674 views

Original Research

Published on 17 Nov 2025

Oxaliplatin versus irinotecan as first-line therapy in metastatic colorectal cancer with prior adjuvant treatment: a retrospective study on efficacy, sequential therapy, and the impact of thrombocytopenia

in Gastrointestinal Cancers: Colorectal Cancer

Han Shan
Shuohan Huang
Changming Zhou
Mengmeng Wang
Qiong Du

Frontiers in Oncology

doi 10.3389/fonc.2025.1631022

1,138 views

Original Research

Published on 17 Nov 2025

Real-time colonoscopic detection and precise segmentation of colorectal polyps via PESNet

in Gastrointestinal Cancers: Colorectal Cancer

Jing Yu
Jianchun Zhu
Qi Gu
Yuhan Sun
Qin Wang
Pengcheng Sun
Liugen Gu

Frontiers in Oncology

doi 10.3389/fonc.2025.1679826

616 views

Original Research

Published on 14 Nov 2025

Predicting early recurrence of colorectal cancer liver metastases: an integrative approach using radiomics and machine learning

in Gastrointestinal Cancers: Colorectal Cancer

Yanzong Lin
Yunxia Huang
Zhaohui Liu
Xiaobin Feng
Chunkang Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1613093

1,151 views

Case Report

Published on 13 Nov 2025

Laparoscopic right hemicolectomy in situs inversus totalis with cecal carcinoma: a case report and literature review

in Gastrointestinal Cancers: Colorectal Cancer

Bowen Su
Yang Zhong
Jiahan Chen
Hongpeng Tian
Tianhao Wu
Guangjun Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1668016

735 views

Original Research

Published on 11 Nov 2025

Clinicopathologic characteristics and prognosis of basaloid squamous cell carcinoma of the rectum in comparison with adenocarcinoma: a retrospective cohort study

in Gastrointestinal Cancers: Colorectal Cancer

Yanyang Zhou
Yi Chang
Haixia Guo
Yanwei Fan
Shijie Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1532525

1,178 views

Original Research

Published on 11 Nov 2025

Deep learning based on MRI for assessing the prognostic value of lateral lymph nodes in rectal cancer

in Gastrointestinal Cancers: Colorectal Cancer

Guanzhong Qiao
Lili Feng
Zhenhui Li
Qiong Wu
Yulin Liu
Jie Zhao
Hao Jiang
Ke Zhao
Yanfen Cui
Huijie Jiang

Frontiers in Oncology

doi 10.3389/fonc.2025.1681939

799 views

Original Research

Published on 10 Nov 2025

BTBD19 promotes colorectal cancer progression and correlates with adverse clinical outcomes

in Gastrointestinal Cancers: Colorectal Cancer

Changjiang Yang
Xuhua Geng
Zihan Zhao

Frontiers in Oncology

doi 10.3389/fonc.2025.1685601

1,134 views

Original Research

Published on 10 Nov 2025

Multiomics analyses of human colorectal cancer reveal changes in mitochondrial metabolism associated with chemotherapy resistance

in Gastrointestinal Cancers: Colorectal Cancer

Shiyi Chen
Qian Li
Wei Zheng

Frontiers in Oncology

doi 10.3389/fonc.2025.1625797

1,222 views

Original Research

Published on 05 Nov 2025

The association between coronary heart disease and the risk of developing colorectal polyps: insights from the UK Biobank

in Gastrointestinal Cancers: Colorectal Cancer

Chi Geng
Ruochong Pang
Yuqing Xia
Yong Wu
Jianhong Zhu
Yong Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1643394

1,434 views

Original Research

Published on 04 Nov 2025

Low expression of SOD and PRX4 as indicators of poor prognosis and systemic inflammation in colorectal cancer

in Gastrointestinal Cancers: Colorectal Cancer

Sanghyun An
Hye Youn Kwon
Kwangmin Kim
Soo-Ki Kim
Cheol Su Kim
Bora Kim
Hyejin Do
Youngwan Kim

Frontiers in Oncology

doi 10.3389/fonc.2025.1614092

935 views
1 citation

Original Research

Published on 04 Nov 2025

Time trends in colorectal cancer incidence across the BRICS: an age-period-cohort analysis for the GBD 2021

in Gastrointestinal Cancers: Colorectal Cancer

Chengcheng Zhang
Linzhi Chen
Chun Zhang
Yuqi Xiu
Hongling Zhang
Wenjuan Ying
Hui Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1633242

1,219 views

Original Research

Published on 29 Oct 2025

Risk factors for parastomal hernia following abdominoperineal resection

in Gastrointestinal Cancers: Colorectal Cancer

An Shang
Liping Li
Ge He
Donggui Zhuge
Pengcheng Yu
Junyi Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1692769

787 views
1 citation

Original Research

Published on 27 Oct 2025

Artemisia absinthium L. ethanol extract inhibits the growth of gastrointestinal cancer cells by inducing apoptosis and mitochondria-dependent pathway

in Gastrointestinal Cancers: Colorectal Cancer

Ting Li
Shaoqi Yu
Zihang Ma
Jinyao Li
Lijie Xia
Yan Feng

Frontiers in Oncology

doi 10.3389/fonc.2025.1644498

1,254 views

Study Protocol

Published on 27 Oct 2025

Multicenter prospective cohort study on colorectal adenoma recurrence and malignant transformation risk based on integrative medicine: a study protocol

in Gastrointestinal Cancers: Colorectal Cancer

Yi-Fan Hui
Shao-Chen Song
Wen-Jian Zhu
Shu Bu
Jin Sun
Ting-Sheng Ling
Hai-Bo Cheng

Frontiers in Oncology

doi 10.3389/fonc.2025.1657390

1,566 views

Correction

Published on 27 Oct 2025

Correction: Prognostic and predictive molecular biomarkers in colorectal cancer

in Gastrointestinal Cancers: Colorectal Cancer

Jianzhi Zhang
Hao Zhu
Wentao Liu
Ji Miao
Yonghuan Mao
Qiang Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1725836

435 views
2 citations

Original Research

Published on 24 Oct 2025

Validated nomograms for non-metastatic colorectal cancer prognosis prediction: a population-based study

in Gastrointestinal Cancers: Colorectal Cancer

Yu-Dan Cao
Hong-Wei Sun
Tian-Ci Li
Jia-Rui Xie
Xin-Ran Shi
Qian Chen
Yue Chen
Zi-Yang Peng
Quan-Peng Qiu
Nuo-Xuan Niu

Frontiers in Oncology

doi 10.3389/fonc.2025.1691693

996 views

Review

Accepted on 22 Oct 2025

Myxofibrosarcoma originating in the small intestine presenting as intestinal obstruction: a case report

in Gastrointestinal Cancers: Colorectal Cancer

Yumin Yue
Yupeng Wang
Zeyu Xu
Zhenzhen Wu
Kai Zhang
Xi Xiaohui
Ke Wang

Frontiers in Oncology

359 views

Original Research

Published on 21 Oct 2025

Colonoscopy outcomes of primary screening negative participants highlight the missed diagnosis problem of colorectal cancer screening: an observational study from Yuexiu district in Guangzhou, China

in Gastrointestinal Cancers: Colorectal Cancer

Yu Liu
Yujing Fang
Yahui Xu
Shuang Wang
Yanping Wu
Kunhao Bai
Paul W. Bible
Qingjian Ou
Meixian Ye
Jiali Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1642326

1,275 views

961 articles

articles

The role of TMEM59L in colorectal cancer progression and its interaction with the TGF-β/Smad pathway

Complete remission of advanced MSI-H rectal cancer in a young patient treated with nivolumab: a case report and critical appraisal of the literature

Global, regional and national burden of colorectal cancer and its risk factors, 1990–2021: a systematic analysis for the GBD 2021

Neoadjuvant Therapy with Cadonilimab in a Patient with MSI-H/dMMR Colorectal Cancer: A Case Report

Deep Learning Analysis of MRI to assess Rectal Cancer Treatment

Reconstruction of a massive abdominal wall defect after colon cancer surgery using bilateral thoracoabdominal flaps and a vertical rectus abdominis myocutaneous flap: a case report

Oxaliplatin versus irinotecan as first-line therapy in metastatic colorectal cancer with prior adjuvant treatment: a retrospective study on efficacy, sequential therapy, and the impact of thrombocytopenia

Real-time colonoscopic detection and precise segmentation of colorectal polyps via PESNet

Predicting early recurrence of colorectal cancer liver metastases: an integrative approach using radiomics and machine learning

Laparoscopic right hemicolectomy in situs inversus totalis with cecal carcinoma: a case report and literature review

Clinicopathologic characteristics and prognosis of basaloid squamous cell carcinoma of the rectum in comparison with adenocarcinoma: a retrospective cohort study

Deep learning based on MRI for assessing the prognostic value of lateral lymph nodes in rectal cancer

BTBD19 promotes colorectal cancer progression and correlates with adverse clinical outcomes

Multiomics analyses of human colorectal cancer reveal changes in mitochondrial metabolism associated with chemotherapy resistance

The association between coronary heart disease and the risk of developing colorectal polyps: insights from the UK Biobank

Low expression of SOD and PRX4 as indicators of poor prognosis and systemic inflammation in colorectal cancer

Time trends in colorectal cancer incidence across the BRICS: an age-period-cohort analysis for the GBD 2021

Risk factors for parastomal hernia following abdominoperineal resection

Artemisia absinthium L. ethanol extract inhibits the growth of gastrointestinal cancer cells by inducing apoptosis and mitochondria-dependent pathway

Multicenter prospective cohort study on colorectal adenoma recurrence and malignant transformation risk based on integrative medicine: a study protocol

Correction: Prognostic and predictive molecular biomarkers in colorectal cancer

Validated nomograms for non-metastatic colorectal cancer prognosis prediction: a population-based study

Myxofibrosarcoma originating in the small intestine presenting as intestinal obstruction: a case report

Colonoscopy outcomes of primary screening negative participants highlight the missed diagnosis problem of colorectal cancer screening: an observational study from Yuexiu district in Guangzhou, China