Frontiers in Oncology | Head and Neck Cancer

Original Research

Published on 06 Oct 2025

Health-related quality of life outcomes from KEYNOTE-412: chemoradiotherapy with or without pembrolizumab in participants with head and neck squamous cell carcinoma

in Head and Neck Cancer

J.-P. Machiels
Y. Tao
L. Licitra
B. Burtness
M. Tahara
D. Rischin
G. V. Alves
I. P. F. Lima
B. G. M. Hughes
Y. Pointreau

Frontiers in Oncology

doi 10.3389/fonc.2025.1645509

376 views

Original Research

Published on 06 Oct 2025

Multifactorial analysis and construction of a nomogram model for postoperative recurrence of glomus jugulare tumor

in Head and Neck Cancer

Kun Li
Qi Lu
Xiaoyan Guo
Ting Kou
Jiyue Chen
Shiming Yang
Weidong Shen

Frontiers in Oncology

doi 10.3389/fonc.2025.1662079

596 views

Original Research

Published on 06 Oct 2025

Comparison of an AI-assisted system (S-detect) and sonographers of different experience levels in diagnosing thyroid nodules: a retrospective study

in Head and Neck Cancer

Zhenhao Zheng
Yang Yu
Jun Li
Ting Ma
Wen Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1656919

240 views

Original Research

Accepted on 03 Oct 2025

Prognostic Significance of Peripheral Blood Inflammatory Biomarkers (SII, PLR, NLR, LMR, SIRI, PIV, PNI) in Lip Cancer: NLR as an Independent Biomarker for Survival Outcomes

in Head and Neck Cancer

Zhilin Li
Wei An
Bin Wang
Zening Yan
Liangbin Gao
Jiaming Wang
Hongmei Yu
Shuxin Wen

Frontiers in Oncology

doi 10.3389/fonc.2025.1676824

134 views

Original Research

Accepted on 01 Oct 2025

Comparison of PD-L1 expression in head and neck squamous cell carcinoma among preoperative biopsy, surgical resection and metastatic lymph node

in Head and Neck Cancer

Heeseung Sohn
Meejeong Kim
Sang-Yeon Kim
Dong-Il Sun
Youn Soo Lee

Frontiers in Oncology

doi 10.3389/fonc.2025.1666078

141 views

Original Research

Published on 01 Oct 2025

Analysis of the predictive value of red cell distribution width (RDW) and hemoglobin-to-RDW ratio (HRR) on the prognosis of patients undergoing total laryngectomy

in Head and Neck Cancer

Zhixuan Fang
Kai Niu

Frontiers in Oncology

doi 10.3389/fonc.2025.1651738

867 views

Original Research

Accepted on 30 Sep 2025

Vascular Interventional Strategies for Recurrent Nasopharyngeal Carcinoma: Diagnostic and Therapeutic Perspectives

in Head and Neck Cancer

Qiang Zhang
Xiang Zhai
Gang Liu
Yanguo Shang
Xiao-Guang Tong
Xingwei An

Frontiers in Oncology

doi 10.3389/fonc.2025.1624138

109 views

Original Research

Published on 30 Sep 2025

Perforator mapping for head and neck reconstructive surgery: a novel personalized approach using magnetic resonance angiography based 3D models and 3D-printing

in Head and Neck Cancer

A.F. de Geer
I. Mulder
L.C. ter Beek
A.S. te Boekhorst
B.I. Plakké
L.H.E. Karssemakers
R. Dirven
P.J.F.M. Lohuis
T.J.M Ruers
F.J. Siepel

Frontiers in Oncology

doi 10.3389/fonc.2025.1655904

546 views

Original Research

Accepted on 29 Sep 2025

Current and future burden trends of lip and oral cavity cancer based on estimated annual 1 percentage change and the bayesian age-period-cohort model: A study based on the global 2 burden of disease 2021

in Head and Neck Cancer

Qiong-Ying Mu
Si-Wen Chen
Min Li
Sheng-Rong Tang

Frontiers in Oncology

doi 10.3389/fonc.2025.1674054

207 views

Original Research

Accepted on 29 Sep 2025

Prediction of Prognosis in T4 or N3 Locally Advanced Nasopharyngeal Carcinoma Receiving Chemoradiotherapy Using Machine Learning Methods

in Head and Neck Cancer

政马
Weijie Liu
Xiaoya Luo
Xinran Niu
Yanmei Li
Yuanling Ma
Li Hou

Frontiers in Oncology

doi 10.3389/fonc.2025.1683501

196 views

Case Report

Published on 29 Sep 2025

Case Report: Free fibula flap for post-oncologic mandibular reconstruction, first experience in Tirana

in Head and Neck Cancer

Alice Marzi Manfroni
Marjon Sako
Nela Mataj
Deniada Zhupa
Francesco Laganà

Frontiers in Oncology

doi 10.3389/fonc.2025.1678310

735 views

Case Report

Published on 26 Sep 2025

The role of ultrasound in diagnosing 2mm medullary thyroid carcinoma with cervical lymph node metastasis: a case report

in Head and Neck Cancer

Qinyun Wan
Li Sun
Lu Gan
Jianxue Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1588295

1,018 views

Original Research

Published on 25 Sep 2025

Increased acid sphingomyelinase levels in saliva as oral mucositis severity predictors

in Head and Neck Cancer

Elsa Beatriz Monroy Ordonez
Tanja Sprave
Andreas R. Thomsen
Henning Schäfer
Anca-Ligia Grosu
Verena Jendrossek
Michael Henke
Kristian Unger
Diana Klein

Frontiers in Oncology

doi 10.3389/fonc.2025.1613884

2,392 views

Original Research

Published on 25 Sep 2025

Global burden of head and neck cancer: Epidemiological transitions, inequities, and projections to 2050

in Head and Neck Cancer

Hao Sun
Mulin Yu
Ziyue An
Fangcheng Liang
Bowen Sun
Yuanlong Liu
Shenquan Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1665019

2,665 views

Original Research

Published on 25 Sep 2025

Development and validation of a multimodal feature fusion-based model for predicting postoperative recurrence-free survival in locally advanced laryngeal squamous cell carcinoma

in Head and Neck Cancer

Feng Zhao
Xiaoying Huang
Jiangmiao Li
Junkun He
Jiaxin Liu
Guanwei Chen
Zhe Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1685737

932 views

Original Research

Published on 25 Sep 2025

Clinical value of intratumoral and peritumoral CT radiomics models for discriminating benign and malignant parotid gland tumors

in Head and Neck Cancer

Cong Zhang
Naijing Shi
Yiru Wang
Mohan Hao
Jinwu Ren

Frontiers in Oncology

doi 10.3389/fonc.2025.1650943

437 views