Frontiers in Oncology | Hematologic Malignancies

Original Research

Published on 14 May 2026

Hybrid handcrafted and deep feature fusion for automated acute myeloid leukemia classification using TCMA-Net on a class-balanced dataset

in Hematologic Malignancies

Osama M. Alshehri
Zohaib Mushtaq
Muhammad Taha
Maham Ijaz
Muhammad Irfan
Malik A. Altayar
Mohammed M. Jalal
Mohammed H. Abu-Alghayth
Humood Al Shmrany
Elhashimi Eltayb Hassan

Frontiers in Oncology

doi 10.3389/fonc.2026.1774702

295 views

Case Report

Published on 14 May 2026

Non-specific skin lesions in angioimmunoblastic T-cell lymphoma lead to diagnosis challenge: a case report and literature review

in Hematologic Malignancies

Zimeng You
Qianqian Wang
Li Xue
Lin Wang
Tingting Wang

Frontiers in Oncology

doi 10.3389/fonc.2026.1785153

164 views

Original Research

Accepted on 13 May 2026

Identification of MTMR2 as an AML-associated candidate biomarker derived from lipid metabolism–related transcriptomic analysis

in Hematologic Malignancies

Chenchen Liu
Yueyuan Pan
Minggui Chen
Songyu Li
Chong Zhang

Frontiers in Oncology

Mini Review

Published on 13 May 2026

The role of EZH2 dysregulation in the pathogenesis of B-cell lymphomas and its implications as a target therapy

in Hematologic Malignancies

Myrna Candelaria

Frontiers in Oncology

doi 10.3389/fonc.2026.1843273

284 views

Original Research

Accepted on 12 May 2026

miR-2110 Orchestrates ERK–ELK1 Transcriptional Repression to Induce Cell-Cycle Arrest and Enhance Cytarabine Sensitivity in Acute Myeloid Leukemia

in Hematologic Malignancies

Ya Li
Ying Chen
Huang Aoshuang
Yun Zhan
Ming NI
Fengqi Zhang
Shaofei Xu
Yanju Li

Frontiers in Oncology

Case Report

Accepted on 12 May 2026

Alectinib shows promise for the treatment of refractory ALK-positive large B-cell lymphoma: a case report

in Hematologic Malignancies

Atheer Alsulami
Roula almufti
Saleem Eldadah
Yahya Al-Ghamdi

Frontiers in Oncology

Case Report

Published on 12 May 2026

Identification of an NFIA::CBFA2T3 fusion in cerebrospinal fluid confirms the diagnosis of pediatric CNS myeloid sarcoma with erythroid differentiation: a case report and literature review

in Hematologic Malignancies

Yang Zhao
Zhizhuo Huang
Lian Xue
Leping Zhang
Yueping Jia

Frontiers in Oncology

doi 10.3389/fonc.2026.1676730

313 views

Original Research

Accepted on 11 May 2026

Clinical Spectrum and Treatment of Thyroid Lymphoma: Results of a Cohort Study of 61 Patients

in Hematologic Malignancies

Shuchang Li
Wenjie Gu
Zhenzhen Yang
Honghan Qiao
Feiyang Zong
Shifeng Hao
Yuxiao Chang
Wanyue Zhao
Xiang Gao
Xudong Zhang

Frontiers in Oncology

Opinion

Accepted on 11 May 2026

Advancing CAR-T Therapy in Multiple Myeloma: A Critical Appraisal of CARTITUDE-4 and the Path Toward Earlier Lines

in Hematologic Malignancies

Ke Qinghua
Chao-qun Zhou
Shi-Qiong Zhou

Frontiers in Oncology

119 views

Original Research

Accepted on 11 May 2026

Prognostic Impact of Early Disease Progression and Early Mortality in Patients with Multiple Myeloma: A Real-World Cohort Study

in Hematologic Malignancies

Nada Vlaisavljević
Ivana Milosevic
Borivoj Sekulić
Jelena Nikolić
Velimir Tomić
Aleksandar Savić

Frontiers in Oncology

Case Report

Accepted on 11 May 2026

Smoldering Waldenström Macroglobulinemia Coexisting with Myelodysplastic Syndrome: A Rare Case Report and Literature Review

in Hematologic Malignancies

Huanyuan Wang
Shuai Tan
Yumeng Li
Wanling Sun

Frontiers in Oncology

Case Report

Published on 11 May 2026

Case Report: Iliac perivascular myeloid sarcoma presenting with iliofemoral deep vein thrombosis and hydronephrosis

in Hematologic Malignancies

Zhao Shan
Yue Wang
Honggang Wang
Jiaxuan He
Hongyi Cai

Frontiers in Oncology

doi 10.3389/fonc.2026.1838693

319 views

Systematic Review

Published on 11 May 2026

Efficacy and safety of FLT3 inhibitors for acute myeloid leukemia: a network meta-analysis

in Hematologic Malignancies

Yaoyao Xu
Jiaming Li
Yao Gao
Gan Huang
Yingjian Zeng

Frontiers in Oncology

doi 10.3389/fonc.2026.1831094

424 views

Case Report

Published on 08 May 2026

Case report: TTMV::RARA-positive pediatric APL with spinal cord compression as initial presentation: unique clinical features and therapeutic outcomes revealed by a 12-case systematic cohort analysis

in Hematologic Malignancies

Hong-Lan Yang
Guo-Yan Xin
Mei-Ting Long
Dan- Chen
Xun Zhao
Meng-Jun Huang
Zheng-Lian Yao
Lin-Qiang Shen
Jian-Juan Ma
Yuan-Yuan Tuo

Frontiers in Oncology

doi 10.3389/fonc.2026.1742593

344 views

Original Research

Accepted on 07 May 2026

Targeting WNK1 suppresses acute myeloid leukemia progression and enhances sensitivity to venetoclax

in Hematologic Malignancies

Fangli Chen
Yuanqin Wang
Zhen Fu
Li Chang
Xuewei Jiang
Zhizhi Zhang
Chongyang Li
Ligen Liu
Li Yang

Frontiers in Oncology

177 views

Case Report

Accepted on 07 May 2026

Primary Diffuse Large B-Cell Lymphoma of the Rectus Abdominis Muscle: A Presumed Primary Case Report and Literature Review

in Hematologic Malignancies

Xuejuan Duan
Xiangyong Yue
Jianlei Cao
Yadong Liu
Zhang Jun
Yuguang Shang

Frontiers in Oncology

108 views

Case Report

Published on 07 May 2026

Case Report: Experience of a rare case of primary acute mast cell leukemia with FGFR1 gene rearrangement

in Hematologic Malignancies

Yalu Liu
Sheng Gao
Huizhen Du
Hong Ji
Zhao Li

Frontiers in Oncology

doi 10.3389/fonc.2026.1830652

326 views

Review

Published on 07 May 2026

Translating advances in primary central nervous system lymphoma: from prognostic stratification to treatment innovation

in Hematologic Malignancies

Zhenjiang Pan
Jing Bao
Shepeng Wei

Frontiers in Oncology

doi 10.3389/fonc.2026.1591328

443 views

Original Research

Accepted on 06 May 2026

CLINICOPATHOLOGICAL FEATURES OF ADULT LYMPHOBLASTIC LYMPHOMA: A RETROSPECTIVE MULTICENTER STUDY FROM TÜRKİYE

in Hematologic Malignancies

Cem Selim
Rafiye Ciftciler
Deniz Goren
Kemal Fidan
ali ünal
hacer berna Afacan Öztürk
murat albayrak
meral uluköylü mengüç
ışık Atagündüz
emel işleyen

Frontiers in Oncology

114 views

Case Report

Accepted on 06 May 2026

Case Report: Borderline Type I/II Cryoglobulinemia Associated with Marginal Zone Lymphoma: A Diagnostic Challenge

in Hematologic Malignancies

Fabiana Crispo
Giovanna Mansueto
Francesca Pia Scioscia
Massimo Dante Di Somma
Diego Petrilli
Biagina Campisi
Fiorella D'Auria
Giulia Anna Carmen Vita
Giovanni D'Arena
Gabriella Bianchino

Frontiers in Oncology

100 views

Review

Accepted on 06 May 2026

Outpatient step-up dosing of bispecific antibodies in relapsed or refractory multiple myeloma: an oncology nursing framework for monitoring and supportive care

in Hematologic Malignancies

YanFeng Song
XiaoFei Zhou
Lina Wang

Frontiers in Oncology

106 views

Case Report

Accepted on 05 May 2026

Disseminated Extranodal NK/T-Cell Lymphoma Presenting with Bilateral Adrenal Masses: A Case Report and Literature Review

in Hematologic Malignancies

Pinyao Liang
Junxiong Li
Yumin Wang
Jingbo Qin
Ruwen Wang
Haotan Li
Yingxia Wang
Xiaodong Liu

Frontiers in Oncology

116 views

Original Research

Accepted on 05 May 2026

A real-world pharmacovigilance study of romidepsin based on FDA adverse event reporting system (FAERS) database

in Hematologic Malignancies

Yuqin Yang
Yaping Huang
Yifan Wang
Yan Chen
Chenjie Ke
Maohua Chen

Frontiers in Oncology

102 views

Original Research

Published on 05 May 2026

ATG16L1 and OPTN as a novel prognostic gene expression signature in acute myeloid leukemia survival

in Hematologic Malignancies

Alexandra Teixeira
João M. Alves
Nuria Estévez-Gómez
Ângela Fernandes
Nuno Cerveira
Susana Bizarro
Manuel R. Teixeira
Manuel Guerreiro
Isabel Castro
Belém Sampaio-Marques

Frontiers in Oncology

doi 10.3389/fonc.2026.1784384

421 views

2,182 articles

articles

Hybrid handcrafted and deep feature fusion for automated acute myeloid leukemia classification using TCMA-Net on a class-balanced dataset

Non-specific skin lesions in angioimmunoblastic T-cell lymphoma lead to diagnosis challenge: a case report and literature review

Identification of MTMR2 as an AML-associated candidate biomarker derived from lipid metabolism–related transcriptomic analysis

The role of EZH2 dysregulation in the pathogenesis of B-cell lymphomas and its implications as a target therapy

miR-2110 Orchestrates ERK–ELK1 Transcriptional Repression to Induce Cell-Cycle Arrest and Enhance Cytarabine Sensitivity in Acute Myeloid Leukemia

Alectinib shows promise for the treatment of refractory ALK-positive large B-cell lymphoma: a case report

Identification of an NFIA::CBFA2T3 fusion in cerebrospinal fluid confirms the diagnosis of pediatric CNS myeloid sarcoma with erythroid differentiation: a case report and literature review

Clinical Spectrum and Treatment of Thyroid Lymphoma: Results of a Cohort Study of 61 Patients

Advancing CAR-T Therapy in Multiple Myeloma: A Critical Appraisal of CARTITUDE-4 and the Path Toward Earlier Lines

Prognostic Impact of Early Disease Progression and Early Mortality in Patients with Multiple Myeloma: A Real-World Cohort Study

Smoldering Waldenström Macroglobulinemia Coexisting with Myelodysplastic Syndrome: A Rare Case Report and Literature Review

Case Report: Iliac perivascular myeloid sarcoma presenting with iliofemoral deep vein thrombosis and hydronephrosis

Efficacy and safety of FLT3 inhibitors for acute myeloid leukemia: a network meta-analysis

Case report: TTMV::RARA-positive pediatric APL with spinal cord compression as initial presentation: unique clinical features and therapeutic outcomes revealed by a 12-case systematic cohort analysis

Targeting WNK1 suppresses acute myeloid leukemia progression and enhances sensitivity to venetoclax

Primary Diffuse Large B-Cell Lymphoma of the Rectus Abdominis Muscle: A Presumed Primary Case Report and Literature Review

Case Report: Experience of a rare case of primary acute mast cell leukemia with FGFR1 gene rearrangement

Translating advances in primary central nervous system lymphoma: from prognostic stratification to treatment innovation

CLINICOPATHOLOGICAL FEATURES OF ADULT LYMPHOBLASTIC LYMPHOMA: A RETROSPECTIVE MULTICENTER STUDY FROM TÜRKİYE

Case Report: Borderline Type I/II Cryoglobulinemia Associated with Marginal Zone Lymphoma: A Diagnostic Challenge

Outpatient step-up dosing of bispecific antibodies in relapsed or refractory multiple myeloma: an oncology nursing framework for monitoring and supportive care

Disseminated Extranodal NK/T-Cell Lymphoma Presenting with Bilateral Adrenal Masses: A Case Report and Literature Review

A real-world pharmacovigilance study of romidepsin based on FDA adverse event reporting system (FAERS) database

ATG16L1 and OPTN as a novel prognostic gene expression signature in acute myeloid leukemia survival