Frontiers in Oncology | Hematologic Malignancies

Original Research

Published on 05 Nov 2025

Severe and/or prolonged COVID-19 in hematologic diseases: clinical implications before and during the omicron era

in Hematologic Malignancies

Akinao Okamoto
Masahiro Yoshida
Senji Kasahara
Takahide Ara
Kazutaka Ozeki
Takanobu Morishita
Daisuke Ikeda
Minoru Kanaya
Tomohiro Kajiguchi
Yasuhiro Suzuki

Frontiers in Oncology

doi 10.3389/fonc.2025.1687204

1,351 views

Systematic Review

Published on 04 Nov 2025

Efficacy and safety of inotuzumab ozogamicin and its combination therapies in acute lymphoblastic leukemia: a systematic review and meta-analysis

in Hematologic Malignancies

Changtao Lao
Jiange Wen
Yuezhen Wen

Frontiers in Oncology

doi 10.3389/fonc.2025.1613777

1,554 views

Original Research

Published on 04 Nov 2025

Mesenchymal stem cells added to second-line therapy improve response and failure-free survival in steroid-refractory acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation: A meta-analysis of randomized controlled trials

in Hematologic Malignancies

Man Xiao
Yinghu Yan
Rui Zhang
Dan Wang
Li Wang
Yameng Zhao
Jinhong Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1704963

1,634 views

Original Research

Published on 03 Nov 2025

Relapsed or refractory central nervous system lymphoma successfully treated by glofitamab combined with lenalidomide

in Hematologic Malignancies

Yin-yin Peng
Xiao-qiong Tang

Frontiers in Oncology

doi 10.3389/fonc.2025.1685271

1,269 views

Perspective

Published on 31 Oct 2025

Unmet needs in patients with acute myeloid leukemia ineligible for intensive approaches: perspectives from a European expert panel

in Hematologic Malignancies

Felicetto Ferrara
Klaus Geissler
Priyanka Mehta
Pau Montesinos
Adriano Venditti

Frontiers in Oncology

doi 10.3389/fonc.2025.1642472

2,015 views

Original Research

Published on 31 Oct 2025

Prognostic value of lymphocyte subsets in diffuse large B cell lymphoma

in Hematologic Malignancies

Lihua Qiu
Lijing Xing
Meng Zhao
Biwen Sun
Xinpei Zhou
Min Li
Guoguang Ying
Huilai Zhang
Chen Tian

Frontiers in Oncology

doi 10.3389/fonc.2025.1671062

1,209 views

Systematic Review

Published on 31 Oct 2025

Safety of totally implantable venous access devices and peripherally inserted central catheters in hematological malignancies patients: a meta-analysis

in Hematologic Malignancies

Meier Gu
Xiaguang Huang

Frontiers in Oncology

doi 10.3389/fonc.2025.1679363

867 views

Original Research

Published on 30 Oct 2025

Testicular lymphoma of 63 patients: a Chinese retrospective, real-world study

in Hematologic Malignancies

Honghan Qiao
Sijun Zhang
Yukai Duan
Renjie Hua
Feiyang Zong
Mingzhi Zhang
Xudong Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1652944

999 views

Editorial

Published on 30 Oct 2025

Editorial: Metabolic dysregulation in hematological malignancies: emerging insights and therapeutic implications

in Hematologic Malignancies

Pengcheng Liu
Jiao Ma
Zizhen Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1701952

815 views

Systematic Review

Published on 30 Oct 2025

Addition of daratumumab to standard triplet regimens achieved better survival in newly diagnosed multiple myeloma: a systematic review and meta-analysis of randomized controlled trials

in Hematologic Malignancies

Bin Hu
Jun Wang
Dan Fang
Ling Jiang
Tianqi Li
Jinxia Cao

Frontiers in Oncology

doi 10.3389/fonc.2025.1619115

1,485 views

Original Research

Published on 28 Oct 2025

Efficacy and safety of hetrombopag in the treatment of chemotherapy-related thrombocytopenia in solid tumors: a retrospective study

in Hematologic Malignancies

Yuan Yuan
Qiang Tong
Jia-hui Liu
Ye Kang

Frontiers in Oncology

doi 10.3389/fonc.2025.1670029

1,099 views

Original Research

Published on 28 Oct 2025

The prognostic significance of incomplete hematological recovery in pediatric patients with low/intermediate risk AML and negative MRD after induction 1

in Hematologic Malignancies

Nessma M. Shahin
Mahmoud Hammad
Hanafy Hafez
Sherine Salem
Nahla El-Sharkawy
Amr Elnashar
Leslie Lehmann
Alaa El-Haddad

Frontiers in Oncology

doi 10.3389/fonc.2025.1661036

1,109 views

Editorial

Published on 27 Oct 2025

Editorial: Immunotherapy and cell therapy for patients with relapsed and refractory acute myeloid leukemia

in Hematologic Malignancies

JingYi Huang
ShiYao Song
Xiaotian Zhang
Chunliang Li
Yan-Lai Tang

Frontiers in Oncology

doi 10.3389/fonc.2025.1691911

963 views

Case Report

Published on 27 Oct 2025

Case Report: Venetoclax combined with hypomethylating agents for the treatment of newly diagnosed with mixed-phenotype acute leukemia and a literature review

in Hematologic Malignancies

Ruihua Mi
Shuli Guo
Weidong Yang
Lin Wang
Yixuan Ma
Lin Chen
Dongbei Li
Xudong Wei

Frontiers in Oncology

doi 10.3389/fonc.2025.1693061

851 views

Original Research

Published on 27 Oct 2025

Post-progression outcomes following BCMA-directed CAR T-cell therapy in myeloma: impact of extramedullary and paramedullary disease

in Hematologic Malignancies

Ziad Abuhelwa
Fnu Amisha
Wenyi Fan
Gabriel De Avila
Doris K. Hansen
Ariel F. Grajales-Cruz
Brandon Blue
Omar Castaneda
Hien Liu
Ciara L. Freeman

Frontiers in Oncology

doi 10.3389/fonc.2025.1663814

1,637 views

Case Report

Published on 24 Oct 2025

Case Report: Dual resistance to dasatinib/olverembatinib in accelerated-phase cml: identification of a novel SPECC1L-inserted e8a2 BCR::ABL1 transcript and ABL1 V379I mutation

in Hematologic Malignancies

Jingjing Fu
Yangming Tang
Xueqin Ruan
Runfa Wang
Tong Chen
Li Jiang
Yanli He
Zhihong Xu
Balian Wang
Haiqin Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1711888

1,125 views

Original Research

Published on 21 Oct 2025

Evaluating the effectiveness of integrated care in targeted therapy for patients with chronic lymphocytic leukemia

in Hematologic Malignancies

Xin Liu
Wumin Chen
Meiying Wang
Yan Gao
Xueqin Kou
Xianna Pan
Lijuan Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1685510

992 views

Original Research

Published on 20 Oct 2025

Unveiling hypoxic regulatory networks by bioinformatics: mechanisms of hypoxia-related hub genes driving rituximab resistance and poor prognosis in DLBCL

in Hematologic Malignancies

Jiayi Yao
Juan Huang
Yuanfei Mao
Zizhen Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1592441

1,547 views

Case Report

Published on 20 Oct 2025

Isolated central nervous system relapse in acute myeloid leukemia: a case report and review of therapeutic challenges

in Hematologic Malignancies

Colin Burns
Ian Muir
Jennifer Foster
Anthony Emanuel
Mark Kochenderfer

Frontiers in Oncology

doi 10.3389/fonc.2025.1667681

1,744 views

Case Report

Published on 17 Oct 2025

Hereditary spherocytosis concomitant with JAK2V617F-positive primary myelofibrosis: a case report

in Hematologic Malignancies

Chi-E Qiu
Lei Lei
Guosong Jiang
Xiuqun Huang
Yadan Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1665179

1,327 views

Case Report

Published on 17 Oct 2025

Acute obinutuzumab-induced thrombocytopenia in follicular lymphoma: case report and literature review

in Hematologic Malignancies

Jieyi Zhou
Miaomiao Chen
Yi Zhang
Ce Xu
Rong Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1643313

1,165 views

Original Research

Published on 16 Oct 2025

Targeting the N-cadherin/β-catenin axis with MSAB reverses malignant phenotypes in blast crisis of CML

in Hematologic Malignancies

Yingying Zhou
Songqin Jian
Lijun Lu
Xiaofang Li
Ruyi Qiu

Frontiers in Oncology

doi 10.3389/fonc.2025.1657508

998 views

Original Research

Published on 16 Oct 2025

B7-H7 knockdown suppresses the proliferation, metastasis, and drug resistance of B-cell non-Hodgkin lymphoma cells by inhibiting the PI3K/Akt pathway

in Hematologic Malignancies

Aili Zhai
Qing Zou
Jiawei Yin
Shixin Ge
Xingfang Xiong
Tao Yan
Xiaoli Xie
Lijuan Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1665309

1,272 views

Systematic Review

Published on 15 Oct 2025

Comparing therapeutic effects of hematopoietic stem cell transplantation, tyrosine kinase inhibitors and chemotherapy in adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia: a systematic review and meta-analysis

in Hematologic Malignancies

Xiaohui Gao
Hui Zeng
Fei Sun
Xiaoyan Zhao
Haibing Wu
Minchao Yan
Yuan Li
Qinyan Fu
Gang Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1627825

1,449 views

2,001 articles

articles

Severe and/or prolonged COVID-19 in hematologic diseases: clinical implications before and during the omicron era

Efficacy and safety of inotuzumab ozogamicin and its combination therapies in acute lymphoblastic leukemia: a systematic review and meta-analysis

Mesenchymal stem cells added to second-line therapy improve response and failure-free survival in steroid-refractory acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation: A meta-analysis of randomized controlled trials

Relapsed or refractory central nervous system lymphoma successfully treated by glofitamab combined with lenalidomide

Unmet needs in patients with acute myeloid leukemia ineligible for intensive approaches: perspectives from a European expert panel

Prognostic value of lymphocyte subsets in diffuse large B cell lymphoma

Safety of totally implantable venous access devices and peripherally inserted central catheters in hematological malignancies patients: a meta-analysis

Testicular lymphoma of 63 patients: a Chinese retrospective, real-world study

Editorial: Metabolic dysregulation in hematological malignancies: emerging insights and therapeutic implications

Addition of daratumumab to standard triplet regimens achieved better survival in newly diagnosed multiple myeloma: a systematic review and meta-analysis of randomized controlled trials

Efficacy and safety of hetrombopag in the treatment of chemotherapy-related thrombocytopenia in solid tumors: a retrospective study

The prognostic significance of incomplete hematological recovery in pediatric patients with low/intermediate risk AML and negative MRD after induction 1

Editorial: Immunotherapy and cell therapy for patients with relapsed and refractory acute myeloid leukemia

Case Report: Venetoclax combined with hypomethylating agents for the treatment of newly diagnosed with mixed-phenotype acute leukemia and a literature review

Post-progression outcomes following BCMA-directed CAR T-cell therapy in myeloma: impact of extramedullary and paramedullary disease

Case Report: Dual resistance to dasatinib/olverembatinib in accelerated-phase cml: identification of a novel SPECC1L-inserted e8a2 BCR::ABL1 transcript and ABL1 V379I mutation

Evaluating the effectiveness of integrated care in targeted therapy for patients with chronic lymphocytic leukemia

Unveiling hypoxic regulatory networks by bioinformatics: mechanisms of hypoxia-related hub genes driving rituximab resistance and poor prognosis in DLBCL

Isolated central nervous system relapse in acute myeloid leukemia: a case report and review of therapeutic challenges

Hereditary spherocytosis concomitant with JAK2V617F-positive primary myelofibrosis: a case report

Acute obinutuzumab-induced thrombocytopenia in follicular lymphoma: case report and literature review

Targeting the N-cadherin/β-catenin axis with MSAB reverses malignant phenotypes in blast crisis of CML

B7-H7 knockdown suppresses the proliferation, metastasis, and drug resistance of B-cell non-Hodgkin lymphoma cells by inhibiting the PI3K/Akt pathway

Comparing therapeutic effects of hematopoietic stem cell transplantation, tyrosine kinase inhibitors and chemotherapy in adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia: a systematic review and meta-analysis