Frontiers in Oncology | Hematologic Malignancies

Original Research

Published on 21 Jan 2026

Regional, demographic and temporal trends in anemia and malignant cancer-related mortality in U.S. older adults: a nationwide CDC WONDER analysis (1999–2020)

in Hematologic Malignancies

Muhammad Sarim Azad Khan
Asma Chaudhary
Mirha Imran Khan
Ibrahiem Azeem Ajaz
Arham Khalid
Aroosha Waheed
Mohammed Hammad Jaber Amin

Frontiers in Oncology

doi 10.3389/fonc.2026.1722891

981 views

Review

Published on 20 Jan 2026

Efficacy and safety of BTK inhibitors in Richter’s transformation: a systematic review of clinical evidence

in Hematologic Malignancies

Canan D. Dirican
Folasade Ajayi
Anas Al Mardini
Bolivia Crocete Aloysia Fernandes
Amara Sofia
Venkatesh Gondhi
Hamid Shaaban
Michael Maroules

Frontiers in Oncology

doi 10.3389/fonc.2025.1681589

1,499 views

Case Report

Published on 20 Jan 2026

Case Report: CD19 CAR-T therapy induces durable remission in a pediatric patient with TP53-mutated, refractory Burkitt lymphoma: a 30-month follow-up

in Hematologic Malignancies

Yong Zhou
Xuerong Shen
Qinwei Chen
Yuping Guo
Dongyan Shen
Rui Su

Frontiers in Oncology

doi 10.3389/fonc.2026.1702660

750 views

Mini Review

Published on 20 Jan 2026

NCOA4 and ferritinophagy in hematological malignancies: a double-edged regulator of iron metabolism and cell fate

in Hematologic Malignancies

T. Chabane
D. Bouscary
E. Grignano

Frontiers in Oncology

doi 10.3389/fonc.2025.1717435

857 views

Case Report

Published on 19 Jan 2026

A rare cytogenetically cryptic MECOM rearrangement in a patient with myelodysplastic neoplasm and SF3B1 mutation identified by RNA sequencing: a case report

in Hematologic Malignancies

Ye Jin
Zi-Jun Xu
Chao-Ran Lv
Zhen Qian
Xiang-Mei Wen
Sheng Xiao
Jiang Lin
Jun Qian

Frontiers in Oncology

doi 10.3389/fonc.2026.1742267

625 views

Case Report

Published on 15 Jan 2026

Case Report: FIA plus venetoclax in a patient on hemodialysis

in Hematologic Malignancies

Jacob E. Herstein
Kayleigh R. Marx
J. Michael Savoy
Wei Ying Jen
Musa Yilmaz
Nicholas J. Short
Ghayas C. Issa
Farhad Ravandi
Tapan M. Kadia
Naval G. Daver

Frontiers in Oncology

doi 10.3389/fonc.2025.1740357

732 views

Review

Published on 14 Jan 2026

Precision immunotherapy with CAR-T cells in pediatric B-cell acute lymphoblastic leukemia: advances and unanswered challenges

in Hematologic Malignancies

Fu Li
Libo Zheng

Frontiers in Oncology

doi 10.3389/fonc.2025.1691189

1,135 views

Case Report

Published on 13 Jan 2026

Case Report: Pediatric AML with TBC1D15::RAB21 fusion and FLT3-ITD/NPM1 co-mutation: diagnostic pitfalls in morphologic mimicry of acute promyelocytic leukemia

in Hematologic Malignancies

Qiang Yao
Xiaoyong Chen
Meizhu Luo
Zhenhu Lin
Xiaoying Fu

Frontiers in Oncology

doi 10.3389/fonc.2025.1683005

851 views

Brief Research Report

Published on 13 Jan 2026

Prognostic and predictive impact of NOTCH1 mutations in patients with chronic lymphocytic leukemia: a tertiary single-center experience

in Hematologic Malignancies

Mattia D’Antiga
Andrea Serafin
Francesco Angotzi
Alessandro Cellini
Arianna Bevilacqua
Giovanni Leone
Nicolò Danesin
Chiara Adele Cavarretta
Francesco Piazza
Erich Piovan

Frontiers in Oncology

doi 10.3389/fonc.2025.1726439

803 views

Case Report

Published on 12 Jan 2026

Sintilimab combined with AVD for the treatment of composite Hodgkin lymphoma and follicular lymphoma: a case report and literature review

in Hematologic Malignancies

Huami Ye
Linlin Huang
Changqian Chen
Shihua Huang
Lianjie Hu
Ling Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1692954

556 views

Case Report

Published on 12 Jan 2026

Headache as the initial symptom in two cases of multiple myeloma: a case report and literature review

in Hematologic Malignancies

Denglu Liu
Minghui Du
Xiaoyu Gao

Frontiers in Oncology

doi 10.3389/fonc.2025.1718989

1,499 views

Original Research

Accepted on 09 Jan 2026

A real-world 10-year follow-up analysis of survival and safety of CD20-targeted therapy in patients with Waldenstrom macroglobulinemia

in Hematologic Malignancies

Xufei Huang
Zhihong Zheng
Zhihong Zheng
Rong Zhan
Shaoyuan Wang

Frontiers in Oncology

173 views

Case Report

Published on 09 Jan 2026

Case Report: Successful treatment of pulmonary lymphomatoid granulomatosis with a PD-1 inhibitor-based regimen

in Hematologic Malignancies

Xiaoyan Liu
Qi Gao
Feifei Wu
Junli Jia
Li Cao
Qingfeng Yu
Dandan Zhang
Wugan Zhao
Jie Ma

Frontiers in Oncology

doi 10.3389/fonc.2025.1700813

755 views

Original Research

Published on 09 Jan 2026

Survival improvement in primary plasma cell leukemia: a retrospective analysis of novel agent-based regimens and stem cell transplantation

in Hematologic Malignancies

Yong Xu
Jie He
Lanxin Chen
Jinwen Liu
Min Zhou
Bing Chen
Hua Bai

Frontiers in Oncology

doi 10.3389/fonc.2025.1727117

790 views

Original Research

Published on 09 Jan 2026

Multi-isocentric volumetric arc-based total body irradiation: radiation dose impact on oncological outcomes in patients receiving allogeneic hematopoietic cell transplantation

in Hematologic Malignancies

Anna Romanowska
Joanna Kamińska
Alicja Sadowska-Klasa
Anita Prawdzik–Dampc
Renata Zaucha

Frontiers in Oncology

doi 10.3389/fonc.2025.1695178

612 views

Original Research

Published on 08 Jan 2026

Prognostic factors associated with recurrent COVID-19 and impact of SARS-CoV-2 vaccine on patients with chronic lymphocytic leukemia

in Hematologic Malignancies

Sara Pepe
Roberta Mazzarella
Costanza Andriola
Tania Soriano
Giorgio Sforzini
Francesca Romana Mauro

Frontiers in Oncology

doi 10.3389/fonc.2025.1737446

933 views

Review

Published on 06 Jan 2026

Ocular toxicities of targeted therapies and immunotherapies in hematologic malignancies

in Hematologic Malignancies

Mohammad S. Aqil
Yzen Al-Marrawi
Marcus Yaldo
Ahmad Abu-Mahfouz
Lavi Singh
Swathi Gopishetty
Precious Idogun
Daniel Ezekwudo
Ishmael Jaiyesimi
Adam J. Weiner

Frontiers in Oncology

doi 10.3389/fonc.2025.1691518

1,480 views

Systematic Review

Published on 06 Jan 2026

Clinical efficacy and safety of umbralisib, a dual PI3Kδ/CK1-ϵ inhibitor, in treatment of hematologic malignancies

in Hematologic Malignancies

Yunke Zang
Hai-en Cheng
Yanhua Sun
Jingfei Wang
Yuying Zhao
Jingning Yang
Yongping Liu
Yanli Sun

Frontiers in Oncology

doi 10.3389/fonc.2025.1591759

809 views

Systematic Review

Published on 06 Jan 2026

Efficacy, safety and economy of denosumab and zoledronic acid in the treatment of bone metastases of solid tumors and multiple myeloma: a systematic review and meta-analysis

in Hematologic Malignancies

Li Zhong
Wei Chen
Da Zheng
Yuening Cao
Ling Zhu
Zefeng Zhu
Luqin Liao
Lilin Dai
Xiaotao Wang
Zheng Zeng

Frontiers in Oncology

doi 10.3389/fonc.2025.1747354

1,218 views

Systematic Review

Published on 06 Jan 2026

Infection risks associated with daratumumab-containing regimens in multiple myeloma: a systematic review and meta-analysis

in Hematologic Malignancies

Zeng-Yi Huang
Xiao-Lian Liu
Ting Li
Chao-Han Luo

Frontiers in Oncology

doi 10.3389/fonc.2025.1729177

1,541 views

Case Report

Published on 05 Jan 2026

Case Report: autologous stem cell boost enables hematopoietic recovery after severe cytopenia induced by BCMA-targeted bispecific antibody therapy in multiple myeloma

in Hematologic Malignancies

Hiroaki Akiyama
Seiji Kakiuchi
Akimasa Sakamoto
Naru Tomigaki
Shutaro Fujioka
Isamu Harima
Ryotaro Niwa
Ikumi Takagi
Yoko Kozuki
Yoshiharu Miyata

Frontiers in Oncology

doi 10.3389/fonc.2025.1705843

1,326 views

Original Research

Published on 05 Jan 2026

Dominant TET2 mutations predict adverse prognosis in cytogenetically normal acute myeloid leukemia patients

in Hematologic Malignancies

Zhuanghui Hao
Jingjing Xia
Sicheng Bian
Miaoke Song
Miao Zhang
Jingyi Feng
Shuo Li
Huichao Wang
Yaofang Zhang
Wanfang Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1730830

1,098 views

Case Report

Published on 05 Jan 2026

Myeloid sarcoma masquerading as central nervous system diffuse large b-cell lymphoma: a case report and literature review

in Hematologic Malignancies

Wanli Hu
Yang Liu
Chengcheng Ma
Yuexian Gao
Pengyun Zeng
Huiling Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1712803

785 views

Case Report

Published on 05 Jan 2026

Case Report: A case of cervical burkitt lymphoma and literature review

in Hematologic Malignancies

Sen Miao
Yue Bai
Hua Hao

Frontiers in Oncology

doi 10.3389/fonc.2025.1696219

545 views

2,059 articles

articles

Regional, demographic and temporal trends in anemia and malignant cancer-related mortality in U.S. older adults: a nationwide CDC WONDER analysis (1999–2020)

Efficacy and safety of BTK inhibitors in Richter’s transformation: a systematic review of clinical evidence

Case Report: CD19 CAR-T therapy induces durable remission in a pediatric patient with TP53-mutated, refractory Burkitt lymphoma: a 30-month follow-up

NCOA4 and ferritinophagy in hematological malignancies: a double-edged regulator of iron metabolism and cell fate

A rare cytogenetically cryptic MECOM rearrangement in a patient with myelodysplastic neoplasm and SF3B1 mutation identified by RNA sequencing: a case report

Case Report: FIA plus venetoclax in a patient on hemodialysis

Precision immunotherapy with CAR-T cells in pediatric B-cell acute lymphoblastic leukemia: advances and unanswered challenges

Case Report: Pediatric AML with TBC1D15::RAB21 fusion and FLT3-ITD/NPM1 co-mutation: diagnostic pitfalls in morphologic mimicry of acute promyelocytic leukemia

Prognostic and predictive impact of NOTCH1 mutations in patients with chronic lymphocytic leukemia: a tertiary single-center experience

Sintilimab combined with AVD for the treatment of composite Hodgkin lymphoma and follicular lymphoma: a case report and literature review

Headache as the initial symptom in two cases of multiple myeloma: a case report and literature review

A real-world 10-year follow-up analysis of survival and safety of CD20-targeted therapy in patients with Waldenstrom macroglobulinemia

Case Report: Successful treatment of pulmonary lymphomatoid granulomatosis with a PD-1 inhibitor-based regimen

Survival improvement in primary plasma cell leukemia: a retrospective analysis of novel agent-based regimens and stem cell transplantation

Multi-isocentric volumetric arc-based total body irradiation: radiation dose impact on oncological outcomes in patients receiving allogeneic hematopoietic cell transplantation

Prognostic factors associated with recurrent COVID-19 and impact of SARS-CoV-2 vaccine on patients with chronic lymphocytic leukemia

Ocular toxicities of targeted therapies and immunotherapies in hematologic malignancies

Clinical efficacy and safety of umbralisib, a dual PI3Kδ/CK1-ϵ inhibitor, in treatment of hematologic malignancies

Efficacy, safety and economy of denosumab and zoledronic acid in the treatment of bone metastases of solid tumors and multiple myeloma: a systematic review and meta-analysis

Infection risks associated with daratumumab-containing regimens in multiple myeloma: a systematic review and meta-analysis

Case Report: autologous stem cell boost enables hematopoietic recovery after severe cytopenia induced by BCMA-targeted bispecific antibody therapy in multiple myeloma

Dominant TET2 mutations predict adverse prognosis in cytogenetically normal acute myeloid leukemia patients

Myeloid sarcoma masquerading as central nervous system diffuse large b-cell lymphoma: a case report and literature review

Case Report: A case of cervical burkitt lymphoma and literature review