Frontiers in Oncology | Hematologic Malignancies

Original Research

Published on 13 Oct 2025

Laboratory and imaging risk factors for mortality in children with primary hemophagocytic lymphohistiocytosis

in Hematologic Malignancies

Jia Huang
Sipei Xu
Rui Tang
Yan Huang
Wei Li
Chundan Gong
Sijie Gao
Hailun Peng
Li Xiao
Wei Ma

Frontiers in Oncology

doi 10.3389/fonc.2025.1668762

1,192 views

Original Research

Published on 13 Oct 2025

Deep learning for scene understanding in mitochondrial dysregulation and blood cancer diagnosis

in Hematologic Malignancies

Feng Zhu
Zihan Liu
Jianming Chang
Yuanyuan Qin
Lulu Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1609851

1,023 views

Case Report

Published on 09 Oct 2025

Case Report: Immunophenotypically diverse immature patterns, including variable TdT expression, in aggressive B-cell lymphomas and leukemia with MYC rearrangement

in Hematologic Malignancies

Daishi Kato
Takahiro Fujino
Reiko Isa
Haruya Okamoto
Taku Tsukamoto
Shinsuke Mizutani
Yuji Shimura
Tsutomu Kobayashi
Hitoji Uchiyama
Masafumi Taniwaki

Frontiers in Oncology

doi 10.3389/fonc.2025.1684005

1,780 views

Mini Review

Published on 08 Oct 2025

Anti-angiogenesis in human lymphomas. New insights

in Hematologic Malignancies

Domenico Ribatti
Roberto Tamma
Giuseppe Ingravallo
Giorgina Specchia

Frontiers in Oncology

doi 10.3389/fonc.2025.1636332

1,318 views

Case Report

Published on 07 Oct 2025

Case Report: Uncommon co-occurrence of different renal histopathological entities in a patient with multiple myeloma and lymphoplasmacytic lymphoma

in Hematologic Malignancies

Marco Talarico
Gisella Vischini
Simona Barbato
Roberta Restuccia
Simone Masci
Ilaria Sacchetti
Enrica Manzato
Stefano Ghibellini
Michele Puppi
Miriam Iezza

Frontiers in Oncology

doi 10.3389/fonc.2025.1672690

1,603 views

Review

Published on 07 Oct 2025

Research advances in the adjunctive diagnosis of acute myeloid leukemia

in Hematologic Malignancies

Wentao Xie
Xinye Jiang
Jingying Huang
Mingwei Qin
Zhisheng Bi

Frontiers in Oncology

doi 10.3389/fonc.2025.1634935

1,919 views

Correction

Published on 06 Oct 2025

Correction: Targeting RAB7 in human B lymphoma by a small molecule inhibitor arrests tumor cell growth

in Hematologic Malignancies

Maria Fernandez
Rui Wang
Jingwei Wang
Shuai Wu
Kenneth Holder
Alia Nazarullah
Ricardo C. T. Aguiar
Zijun Y. Xu-Monette
Ken H. Young
Hui Yan

Frontiers in Oncology

doi 10.3389/fonc.2025.1711784

1,067 views

Original Research

Published on 03 Oct 2025

Improvement of revised international staging system risk stratification in patients with newly diagnosed multiple myeloma using a high bone marrow plasma cell percentage: a real-world study in China

in Hematologic Malignancies

Xiaoman Sun
Min Song
Pengyu Wang
Zhongmei Zhang
Rongqin Dai
Jie Shi

Frontiers in Oncology

doi 10.3389/fonc.2025.1627653

1,568 views

Original Research

Published on 02 Oct 2025

Ibrutinib combined with rituximab and high-dose methotrexate in newly diagnosed primary CNS diffuse large B-cell lymphoma: a pilot study with long-term follow-up

in Hematologic Malignancies

Yixian Guo
Yongzhi Shan
Yueshan Piao
Xiaoli Chang
Dongmei Zou
Qiang Ma
Yukui Wei
Geng Xu
Yaming Wang
Dandan Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1669385

2,775 views

Brief Research Report

Published on 01 Oct 2025

Current quality of life questionnaires are not relevant for assessing QOL issues in multiple myeloma patients in the era of modern therapies: results from a survey with myeloma patients and myeloma healthcare professionals

in Hematologic Malignancies

Catherine S. Y. Lecat
Sotirios Bristogiannis
Dipal Mehta
Yadanar Lwin
Joanne Land
Orla McCourt
Emma Dowling
Nuno Correia
Neil K. Rabin
Ke Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1656912

1,358 views

Case Report

Published on 01 Oct 2025

Case Report: A rare RUNX1 rearrangement resulting from t(8;21)(p12;q22) in acute myeloid leukemia with plasmacytoid dendritic cell expansion

in Hematologic Malignancies

Jinying Gong
Jialong Liu
Lisha Lu
Jiru Wei
Xue Wu
Junyan Zou
Yuan Feng
Guoqing Zhu
Jing Han

Frontiers in Oncology

doi 10.3389/fonc.2025.1672416

1,506 views

Original Research

Published on 30 Sep 2025

The significance of PET/CT combined with machine learning models for the classification of lymphoma involvement and metastases in enlarged lymph nodes

in Hematologic Malignancies

Jingyi Ren
Jinbo Lu
Xun Shi
Yuexin Cheng

Frontiers in Oncology

doi 10.3389/fonc.2025.1643924

1,174 views

Case Report

Published on 25 Sep 2025

Zanubrutinib as a salvage therapy for ibrutinib-resistant chronic lymphocytic leukemia: a case report

in Hematologic Malignancies

Zhenhui Lv
Ping Lu
Changhua Jing
Xuena Yi
Xueqiong Wu

Frontiers in Oncology

doi 10.3389/fonc.2025.1671124

3,153 views

Case Report

Published on 23 Sep 2025

Efficacy of brentuximab vedotin combined with sintilimab in relapsed/refractory DLBCL patient with secondary hemophagocytic syndrome: a case report and literature review

in Hematologic Malignancies

Siyu Cheng
Huihong Wu
Wenguang Bao
Zhigang Peng
Fengxiang Huang
Shengsheng Zhou
Qinli Mo
Ye Li
Yehong Bin
Dong Lan

Frontiers in Oncology

doi 10.3389/fonc.2025.1531713

1,732 views

Mini Review

Published on 23 Sep 2025

Immunoparesis in multiple myeloma: a current overview

in Hematologic Malignancies

Hongfeng Wang
Jianbin Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1628144

2,020 views

Case Report

Published on 22 Sep 2025

Erdheim-Chester disease: unveiling hidden manifestations through two case reports

in Hematologic Malignancies

Guoxia Zhang
Xiaoqing Yang
Lei Fang
Yuxia Cheng
Yanhua Duan
Jing Cui

Frontiers in Oncology

doi 10.3389/fonc.2025.1611907

1,184 views

Original Research

Published on 22 Sep 2025

Targeting RAB7 in human B lymphoma by a small molecule inhibitor arrests tumor cell growth

in Hematologic Malignancies

Maria Fernandez
Rui Wang
Jingwei Wang
Shuai Wu
Kenneth Holder
Alia Nazarullah
Ricardo C. T. Aguiar
Zijun Y. Xu-Monette
Ken H. Young
Hui Yan

Frontiers in Oncology

doi 10.3389/fonc.2025.1616519

1,936 views

Mini Review

Published on 22 Sep 2025

Lower dose and weekly schedules of selinexor in multiple myeloma - updated evidence on safety and efficacy

in Hematologic Malignancies

Muhamed Baljevic
Gary Schiller
Tomer M. Mark
Dane R. Van Domelen
Cristina Gasparetto

Frontiers in Oncology

doi 10.3389/fonc.2025.1649493

1,885 views

Systematic Review

Published on 19 Sep 2025

Prognostic and clinicopathological value of prognostic nutritional index in patients with multiple myeloma: a meta-analysis

in Hematologic Malignancies

Yanchen Nie
Zongxin Zhang
Xiaohuan Tang

Frontiers in Oncology

doi 10.3389/fonc.2025.1545096

2,978 views

Case Report

Published on 18 Sep 2025

Case Report: A chronic myeloid leukemia patient with e8a2 BCR::ABL1 fusion transcript was successfully treated with Flumatinib

in Hematologic Malignancies

Shanfeng Hao
Yao Zhang
Qing Shao
Lijuan Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1670115

1,513 views
1 citation

Case Report

Published on 18 Sep 2025

Venetoclax as a cytoreduction therapy option for acute promyelocytic leukemia in newly diagnosed adult patients: a case report of a 35-year-old female with schizophrenia

in Hematologic Malignancies

Lingling Wang
Yuqing Miao
Yuexin Cheng

Frontiers in Oncology

doi 10.3389/fonc.2025.1671529

1,429 views

Case Report

Published on 17 Sep 2025

Case report: Histiocytic sarcoma as transdifferentiation of a marginal zone lymphoma—a case presentation based on post mortem examination and review of the literature

in Hematologic Malignancies

Annaïse J. Jauch
Ilaria Alborelli
Ilaria Balestri
Fatime Krasniqi
Alexandar Tzankov
Benjamin Kasenda
Thomas Menter

Frontiers in Oncology

doi 10.3389/fonc.2025.1609694

2,636 views

Original Research

Published on 17 Sep 2025

Integration of autophagy-related genes and immune dysregulation reveals a prognostic landscape in multiple myeloma

in Hematologic Malignancies

Yibo Xia
Dong Zheng
Xinyi Zhang
Shuxia Zhu
Enqing Lan
Hansen Ying
Zixing Chen
Bingxin Zhang
Shujuan Zhou
Yu Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1635596

1,273 views

Original Research

Published on 16 Sep 2025

A discrete choice experiment analysis to understand patient preferences for multiple myeloma treatments

in Hematologic Malignancies

Beth Faiman
Hoa H. Le
Julie Laurent
Saurabh Patel
Agne Paner-Straseviciute
Xinke Zhang
Joseph Mikhael

Frontiers in Oncology

doi 10.3389/fonc.2025.1628121

2,407 views

2,001 articles

articles

Laboratory and imaging risk factors for mortality in children with primary hemophagocytic lymphohistiocytosis

Deep learning for scene understanding in mitochondrial dysregulation and blood cancer diagnosis

Case Report: Immunophenotypically diverse immature patterns, including variable TdT expression, in aggressive B-cell lymphomas and leukemia with MYC rearrangement

Anti-angiogenesis in human lymphomas. New insights

Case Report: Uncommon co-occurrence of different renal histopathological entities in a patient with multiple myeloma and lymphoplasmacytic lymphoma

Research advances in the adjunctive diagnosis of acute myeloid leukemia

Correction: Targeting RAB7 in human B lymphoma by a small molecule inhibitor arrests tumor cell growth

Improvement of revised international staging system risk stratification in patients with newly diagnosed multiple myeloma using a high bone marrow plasma cell percentage: a real-world study in China

Ibrutinib combined with rituximab and high-dose methotrexate in newly diagnosed primary CNS diffuse large B-cell lymphoma: a pilot study with long-term follow-up

Current quality of life questionnaires are not relevant for assessing QOL issues in multiple myeloma patients in the era of modern therapies: results from a survey with myeloma patients and myeloma healthcare professionals

Case Report: A rare RUNX1 rearrangement resulting from t(8;21)(p12;q22) in acute myeloid leukemia with plasmacytoid dendritic cell expansion

The significance of PET/CT combined with machine learning models for the classification of lymphoma involvement and metastases in enlarged lymph nodes

Zanubrutinib as a salvage therapy for ibrutinib-resistant chronic lymphocytic leukemia: a case report

Efficacy of brentuximab vedotin combined with sintilimab in relapsed/refractory DLBCL patient with secondary hemophagocytic syndrome: a case report and literature review

Immunoparesis in multiple myeloma: a current overview

Erdheim-Chester disease: unveiling hidden manifestations through two case reports

Targeting RAB7 in human B lymphoma by a small molecule inhibitor arrests tumor cell growth

Lower dose and weekly schedules of selinexor in multiple myeloma - updated evidence on safety and efficacy

Prognostic and clinicopathological value of prognostic nutritional index in patients with multiple myeloma: a meta-analysis

Case Report: A chronic myeloid leukemia patient with e8a2 BCR::ABL1 fusion transcript was successfully treated with Flumatinib

Venetoclax as a cytoreduction therapy option for acute promyelocytic leukemia in newly diagnosed adult patients: a case report of a 35-year-old female with schizophrenia

Case report: Histiocytic sarcoma as transdifferentiation of a marginal zone lymphoma—a case presentation based on post mortem examination and review of the literature

Integration of autophagy-related genes and immune dysregulation reveals a prognostic landscape in multiple myeloma

A discrete choice experiment analysis to understand patient preferences for multiple myeloma treatments