Frontiers in Oncology | Hematologic Malignancies

Case Report

Published on 05 Sep 2025

Successful CD19 chimeric antigen receptor T-cell therapy following autologous stem cell transplantation in a secondary central nervous system lymphoma patient with COVID-19 infection: a case report and literature review

in Hematologic Malignancies

Xiaoning Wang
Juan Ren
Yuqi Wang
Minna Luo
Jing Li
Pengcheng He

Frontiers in Oncology

doi 10.3389/fonc.2025.1656034

1,997 views

Original Research

Published on 03 Sep 2025

IONPs combined with cytarabine downregulated IFITM3 expression to inhibit acute myeloid leukemia

in Hematologic Malignancies

Jun Dou
Feng Mei
Hui Xu
Xue Rui
Xueyang Bao
Kena Liu
Fengsu Zhao

Frontiers in Oncology

doi 10.3389/fonc.2025.1515956

1,721 views

Case Report

Published on 03 Sep 2025

Case Report: Unraveling complex genomic alterations in a case of chronic lymphocytic leukemia using optical genome mapping

in Hematologic Malignancies

Leila Youssefian
Trilochan Sahoo
Jia-Chi Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1639849

2,514 views

Original Research

Published on 03 Sep 2025

Machine learning-based nomogram predicts heart failure risk in elderly relapsed/refractory multiple myeloma patients receiving carfilzomib-based therapy

in Hematologic Malignancies

Dan Qiao
Hai-bin Ding
Cong-hui Zhu
Ren-an Chen
Lei Nie

Frontiers in Oncology

doi 10.3389/fonc.2025.1624680

2,132 views

Original Research

Published on 02 Sep 2025

Risk factors for thrombotic events in Philadelphia chromosome-negative myeloproliferative neoplasms: a retrospective analysis of 336 cases

in Hematologic Malignancies

Lingxiu Zhang
Xiufeng Wang
Man Yang
Youmei Zi
Yuan Zhang
Yan Guo
Guoqing Lv
Sun Wu
Yan Huang

Frontiers in Oncology

doi 10.3389/fonc.2025.1639250

2,183 views
1 citation

Clinical Trial

Published on 02 Sep 2025

Effectiveness and safety profile of chidamide as maintenance therapy for peripheral T-cell lymphoma: a multicenter real-world study

in Hematologic Malignancies

Wenjing Jiang
Xiyuan Zhang
Wei Song
Hong Xu
Changrong Wei
Juan Wang
Ling Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1596270

1,819 views

Original Research

Published on 29 Aug 2025

Real-world data on adult AML with FLT3-ITD mutation from the Thai acute leukemia working group

in Hematologic Malignancies

Thanawat Rattanathammethee
Ekarat Rattarittamrong
Chinadol Wanitpongpun
Smith Kungwankiattichai
Weerapat Owattanapanich
Chantiya Chanswangphuwana
Chantana Polprasert
Thanakrit Piyajaroenkij
Pimjai Niparuck
Supawee Saengboon

Frontiers in Oncology

doi 10.3389/fonc.2025.1606943

2,821 views

Case Report

Published on 29 Aug 2025

Case Report: Transformation of natural killer-cell large granular lymphocytic leukemia to aggressive natural killer cell leukemia

in Hematologic Malignancies

Wen Wang
Ke Lu
Lijie Xing
Zengjun Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1648711

2,148 views

Original Research

Published on 29 Aug 2025

A case report of TBL1XR1-RARB positive pediatric acute promyelocytic leukemia and literature review

in Hematologic Malignancies

Chunyan Du
Fu Liu
Linlin Huang
Ruxue Zeng
Jiamei Fan
Tao Hu

Frontiers in Oncology

doi 10.3389/fonc.2025.1566404

1,929 views

Brief Research Report

Published on 27 Aug 2025

The prognostic value of health-related quality of life for early molecular response in patients with chronic myeloid leukemia: analysis of the GIMEMA-SUSTRENIM trial

in Hematologic Malignancies

Fabio Efficace
Laura Cannella
Isabella Capodanno
Rosaria Sancetta
Veronica Porcu
Monia Lunghi
Annalisa Biagi
Fausto Castagnetti
Giovanni Caocci
Thomas Baldi

Frontiers in Oncology

doi 10.3389/fonc.2025.1645217

1,938 views

Brief Research Report

Published on 26 Aug 2025

Identification of a novel PRMD16::SKI fusion gene in T-prolymphocytic leukemia

in Hematologic Malignancies

Marta Brunetti
Hilde Kollsete Gjelberg
Håkon Reikvam
Francesca Micci

Frontiers in Oncology

doi 10.3389/fonc.2025.1658257

2,184 views

Original Research

Published on 26 Aug 2025

Real-world cardiovascular risks of ibrutinib in chronic lymphocytic leukemia: a retrospective study

in Hematologic Malignancies

Jelena Ivanovic
Vladimir Otasevic
Ksenija Markovic
Vojin Vukovic
Tamara Bibic
Kristina Tomic Vujovic
Sofija Kozarac
Jelena Vladicic Masic
Natasa Milic
Jovan Kulic

Frontiers in Oncology

doi 10.3389/fonc.2025.1624761

2,523 views
1 citation

Case Report

Published on 25 Aug 2025

Successful remission induction therapy with azacitidine and venetoclax for a treatment-naive elderly patient with ETP/myeloid mixed-phenotype acute leukemia: a case report

in Hematologic Malignancies

Kaikai Huang
Yanbin Pang

Frontiers in Oncology

doi 10.3389/fonc.2025.1628767

3,014 views
1 citation

Systematic Review

Published on 22 Aug 2025

CD20×CD3 bispecific antibody achieved significant efficacy in patients with large B-cell lymphoma relapsing after or refractory to CAR-T therapy: a systematic review and meta-analysis

in Hematologic Malignancies

Jing Shen
Jingyi Zhang
Zhengyu Zhu
Haobo Ma
Xiayan Li
Junpeng Zhang
Fan Zhou
Hua Tian
Jinghua Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1641769

3,879 views

Case Report

Published on 20 Aug 2025

Extramedullary relapse of acute lymphoblastic leukemia treated with a CAR-T cell therapy bridge to unrelated cord blood transplantation: a case report and review of the literature

in Hematologic Malignancies

Huibo Li
Jie Liu
Dan Guo
Yanqiu Zhao
Qi Li
Sen Qi
Jinxiao Hou
Jianping Zhang
Shengjin Fan

Frontiers in Oncology

doi 10.3389/fonc.2025.1508676

2,938 views

Case Report

Published on 20 Aug 2025

Case Report: Diagnosis of splenic marginal zone lymphoma by ultrasound and contrast- enhanced ultrasound

in Hematologic Malignancies

Xu Zhang
Jianghao Lu
Yanli Hao
Tingting Wu
Zeyan Gao
Peng Zhou

Frontiers in Oncology

doi 10.3389/fonc.2025.1569962

2,152 views

Review

Published on 20 Aug 2025

TP53-mutated MDS and AML: immune dysregulation, tumor microenvironment, and emerging therapeutic strategies

in Hematologic Malignancies

Marwah M. Albakri

Frontiers in Oncology

doi 10.3389/fonc.2025.1655486

6,890 views
1 citation

Original Research

Published on 19 Aug 2025

Real-world Australian experience with tisagenlecleucel for relapsed/refractory diffuse large B-cell lymphoma—importance of pre-CAR-T optimization

in Hematologic Malignancies

Phoebe Joy Ho
Vinay Vanguru
Cale S. Burge
Rebecca Wayte
Christina Brown
Christian E. Bryant
Scott Dunkley
Derek McCulloch
Liane Khoo
James Favaloro

Frontiers in Oncology

doi 10.3389/fonc.2025.1633644

2,832 views

Case Report

Published on 18 Aug 2025

Obinutuzumab combined with bendamustine for the treatment of hairy cell leukemia variant: a case report and literature review

in Hematologic Malignancies

Junjun Bai
Yi Zhang
Kangqi Lv
Bei Zhang
Hongxia Wang
Zhixin Pei
Yingxin Zhao
Jingjing Gu
Huimin Wu
Qinglin Song

Frontiers in Oncology

doi 10.3389/fonc.2025.1635856

1,844 views

Original Research

Published on 13 Aug 2025

Diagnostic and therapeutic pathways for lymphoma patients: expert consensus through Nominal Group Technique and Delphi methodology

in Hematologic Malignancies

Attilio Guarini
Valentina Bozzoli
Sabino Ciavarella
Michele Cimminiello
Francesca Donatelli
Angelo Fama
Vincenza Fernanda Fesce
Vincenzo Fraticelli
Francesco Gaudio
Giuseppina Greco

Frontiers in Oncology

doi 10.3389/fonc.2025.1627175

3,468 views

Original Research

Published on 13 Aug 2025

Implementing comprehensive geriatric assessment in an academic hematologic outpatient setting: experiences from medical doctors and patients

in Hematologic Malignancies

Steven Pierre Hiltgen
Heike A. Bischoff-Ferrari
Michael Gagesch
Alexander Kaltenborn
Markus G. Manz
Max J. Rieger
Rahel Schwotzer
Sebastian M. Stolz
Thorsten Zenz
Wiebke Rösler

Frontiers in Oncology

doi 10.3389/fonc.2025.1570889

1,939 views

Case Report

Published on 13 Aug 2025

Case Report: Simnotrelvir/Ritonavir are effective in shortening the course of prolonged SARS-CoV-2 infection during anti-CD20 maintenance therapy in patients with follicular lymphoma

in Hematologic Malignancies

Jing Yang
Shengke Tu
Hui Peng
Yuanyuan Peng
Min Li
Kui Song

Frontiers in Oncology

doi 10.3389/fonc.2025.1583932

1,884 views

Case Report

Published on 13 Aug 2025

Novel e4a2 BCR∷ABL1 transcript with insertion of CSE1L exons 9 and 10 in a CML patient: a case report

in Hematologic Malignancies

Sara Di Giusto
Eleonora Toffoletti
Cinzia Cozzarolo
Tomas Liani
Moira Moro
Renato Fanin
Daniela Damiani
Mario Tiribelli

Frontiers in Oncology

doi 10.3389/fonc.2025.1596256

1,675 views

Original Research

Published on 12 Aug 2025

Development and validation of a machine learning-based early warning system for predicting venous thromboembolism risk in hospitalized lymphoma patients undergoing chemotherapy: a multicenter and retrospective cohort study

in Hematologic Malignancies

Tingting Jiang
Zailin Yang
Xinyi Tang
Na Fan
Zuhai Hu
Jieping Li
Tingting Liu
Yu Peng
Shuang Chen
Bingling Guo

Frontiers in Oncology

doi 10.3389/fonc.2025.1566905

2,545 views
1 citation

2,064 articles

articles

Successful CD19 chimeric antigen receptor T-cell therapy following autologous stem cell transplantation in a secondary central nervous system lymphoma patient with COVID-19 infection: a case report and literature review

IONPs combined with cytarabine downregulated IFITM3 expression to inhibit acute myeloid leukemia

Case Report: Unraveling complex genomic alterations in a case of chronic lymphocytic leukemia using optical genome mapping

Machine learning-based nomogram predicts heart failure risk in elderly relapsed/refractory multiple myeloma patients receiving carfilzomib-based therapy

Risk factors for thrombotic events in Philadelphia chromosome-negative myeloproliferative neoplasms: a retrospective analysis of 336 cases

Effectiveness and safety profile of chidamide as maintenance therapy for peripheral T-cell lymphoma: a multicenter real-world study

Real-world data on adult AML with FLT3-ITD mutation from the Thai acute leukemia working group

Case Report: Transformation of natural killer-cell large granular lymphocytic leukemia to aggressive natural killer cell leukemia

A case report of TBL1XR1-RARB positive pediatric acute promyelocytic leukemia and literature review

The prognostic value of health-related quality of life for early molecular response in patients with chronic myeloid leukemia: analysis of the GIMEMA-SUSTRENIM trial

Identification of a novel PRMD16::SKI fusion gene in T-prolymphocytic leukemia

Real-world cardiovascular risks of ibrutinib in chronic lymphocytic leukemia: a retrospective study

Successful remission induction therapy with azacitidine and venetoclax for a treatment-naive elderly patient with ETP/myeloid mixed-phenotype acute leukemia: a case report

CD20×CD3 bispecific antibody achieved significant efficacy in patients with large B-cell lymphoma relapsing after or refractory to CAR-T therapy: a systematic review and meta-analysis

Extramedullary relapse of acute lymphoblastic leukemia treated with a CAR-T cell therapy bridge to unrelated cord blood transplantation: a case report and review of the literature

Case Report: Diagnosis of splenic marginal zone lymphoma by ultrasound and contrast- enhanced ultrasound

TP53-mutated MDS and AML: immune dysregulation, tumor microenvironment, and emerging therapeutic strategies

Real-world Australian experience with tisagenlecleucel for relapsed/refractory diffuse large B-cell lymphoma—importance of pre-CAR-T optimization

Obinutuzumab combined with bendamustine for the treatment of hairy cell leukemia variant: a case report and literature review

Diagnostic and therapeutic pathways for lymphoma patients: expert consensus through Nominal Group Technique and Delphi methodology

Implementing comprehensive geriatric assessment in an academic hematologic outpatient setting: experiences from medical doctors and patients

Case Report: Simnotrelvir/Ritonavir are effective in shortening the course of prolonged SARS-CoV-2 infection during anti-CD20 maintenance therapy in patients with follicular lymphoma

Novel e4a2 BCR∷ABL1 transcript with insertion of CSE1L exons 9 and 10 in a CML patient: a case report

Development and validation of a machine learning-based early warning system for predicting venous thromboembolism risk in hospitalized lymphoma patients undergoing chemotherapy: a multicenter and retrospective cohort study