Frontiers in Oncology | Neuro-Oncology and Neurosurgical Oncology

Case Report

Published on 10 Dec 2025

Case Report: A rare case of bone destructive sacrococcygeal chordoma presenting as anal distension

in Neuro-Oncology and Neurosurgical Oncology

Xianshui Mei
Ming Li
Kun Tang
Ran Tang
Xudong Wang
Ping Cheng
Li Chen
Afen Wu
Jiuxiang Wang
Jianming Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1672249

430 views

Original Research

Published on 09 Dec 2025

Sialylation-related gene signature predict prognosis and immunotherapy efficacy in low- and high-grade glioma: a PCA-based stratification study

in Neuro-Oncology and Neurosurgical Oncology

Guidong Zhu
Yan Liu
Rui Liu
Guoqiang Xin
Chengke Zhang
Chengwei Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1676103

583 views

Original Research

Accepted on 08 Dec 2025

High Intra-tumoral and Serum Matrix Metalloproteinase 9 Levels are Associated with Reduced Survival of Patients with Glioblastoma and Brain Metastases

in Neuro-Oncology and Neurosurgical Oncology

Tehila Kaisman-Elbaz
Snir Haddad-Shlaifshtein
Yael Eskira
Vladimir Merkin
Guy Dumanis
Sivan Turiel
Maya Atar
Romi Bari
Adi Alt
Tali Zamed

Frontiers in Oncology

Original Research

Accepted on 08 Dec 2025

A Comprehensive Evaluation of MRI-based Radiogenomics and Prognosis Prediction in Glioma

in Neuro-Oncology and Neurosurgical Oncology

Mehdi Astaraki
Marta Lazzeroni
Iuliana Toma-Dasu

Frontiers in Oncology

Case Report

Accepted on 08 Dec 2025

Secondary Exophytic Glioblastoma of the Cerebellopontine Angle: A Case Report and Review of the Literature

in Neuro-Oncology and Neurosurgical Oncology

Lirui Dai
Shu Jiang
Peizhi Zhou

Frontiers in Oncology

149 views

Original Research

Accepted on 08 Dec 2025

ASPHD1 Is a Tumor-Suppressive and Prognostic Marker in Glioma

in Neuro-Oncology and Neurosurgical Oncology

Jinhua Yang
Fenfei Gao
Xiaowan Wang
Yanmei Zhang

Frontiers in Oncology

202 views

Original Research

Published on 08 Dec 2025

CD58 reshapes the immunosuppressive microenvironment in gliomas through PD-L1 upregulation

in Neuro-Oncology and Neurosurgical Oncology

Siqi Gou
Pengfei Zhao
Lei Zong
Daihua Yu
Wei Liu
Weichen Zuo
Juanhong Wang
Wei Wei

Frontiers in Oncology

doi 10.3389/fonc.2025.1658467

482 views

Original Research

Published on 08 Dec 2025

LncRNA ZFHX4-AS1 initiates an oncogenic axis involving a ZFHX4/SOX2 positive feedback loop to accelerate glioma progression

in Neuro-Oncology and Neurosurgical Oncology

Hongshan Yan
Xue Wang
Zongmao Zhao

Frontiers in Oncology

doi 10.3389/fonc.2025.1687984

534 views

Correction

Published on 03 Dec 2025

Correction: Case Report: FGFR1 mutation and massive chromosome loss drive malignant transformation of low-grade gliomas

in Neuro-Oncology and Neurosurgical Oncology

Ruze Tang
Yanming Chen
Dong Wan
Yongjun Xiang
Si Chen
Huafei Chen
Xiaoxiao Dai
Rong Rong
Sheng Xiao
Qing Lan

Frontiers in Oncology

doi 10.3389/fonc.2025.1748919

380 views

Original Research

Published on 02 Dec 2025

Multiparametric-MRI habitat radiomics analysis for discriminating pathological types of brain metastases

in Neuro-Oncology and Neurosurgical Oncology

Jinling Zhu
Xin Xie
Jixuan Deng
Ruizhe Xu
Li Zou
Ye Tian
Wu Cai
Bo Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1714315

746 views

Original Research

Published on 27 Nov 2025

Patient selection and outcome in low-grade glioma surgery

in Neuro-Oncology and Neurosurgical Oncology

Margret Jensdottir
Ole Solheim
Alba Corell
Eddie de Dios
Tora Dunås
Alexander Fletcher-Sandersjöö
Sasha Gulati
Klas Holmgren
Francesco Latini
Ruby Mahesparan

Frontiers in Oncology

doi 10.3389/fonc.2025.1703756

1,161 views

Original Research

Published on 27 Nov 2025

Isoform-specific vs. pan-histone deacetylase inhibition as approaches for countering glioblastoma: an in vitro study

in Neuro-Oncology and Neurosurgical Oncology

Ameya Joshi
Natasha Ratnapradipa
Jayce Hughes
Erik Moore
Andrew Ekpenyong
Surabhi Shukla

Frontiers in Oncology

doi 10.3389/fonc.2025.1695552

808 views

Original Research

Published on 27 Nov 2025

The glioblastoma virome across tumor and extracellular compartments

in Neuro-Oncology and Neurosurgical Oncology

Mahin Ghorbani
Hamed Karimi
Farnoosh Solati
Nazanin Anbarestani
Nooshin Khoshdoozmasouleh

Frontiers in Oncology

doi 10.3389/fonc.2025.1705003

905 views

Original Research

Published on 26 Nov 2025

Multicenter evaluation of preoperative and standalone embolization in meningiomas

in Neuro-Oncology and Neurosurgical Oncology

Duan Yu
Guohui Huang
Jun Shen
Yanan Li
Jie Xu
Ziwei Xu
Jian Li
Dongwei Dai

Frontiers in Oncology

doi 10.3389/fonc.2025.1626753

566 views

Mini Review

Accepted on 25 Nov 2025

Electrophysiology of gliomas: current science, implications, and opportunities

in Neuro-Oncology and Neurosurgical Oncology

Hanna E. Minns, BS
Nemanja Useinovic, MD
Jordan L. Smith, MD, PhD
Sushant Puri
Ahmed M. Raslan, MD, FAANS
Angelique C. Paulk, PhD
Daniel R. Cleary, MD, PhD

Frontiers in Oncology

148 views

Case Report

Accepted on 25 Nov 2025

TREATMENT CHALLENGES IN GLIOBLASTOMA – A CASE REPORT

in Neuro-Oncology and Neurosurgical Oncology

Roda Domingos
Filipa Oliveira
Pedro Veiga
Leonor Santos
Pedro Abreu
Ana Nascimento
Francisco José Caramelo
Joana B Melo
Isabel Carreira
Ilda Patrícia Ribeiro

Frontiers in Oncology

154 views

Original Research

Published on 25 Nov 2025

MRI-based radiomic clustering identifies a glioblastoma subtype enriched for neural stemness and proliferative programs

in Neuro-Oncology and Neurosurgical Oncology

Zhongyi Zhang
Yang Liu
Zhicong Zhang
Tian Gui
Youhui Chen
Qian Chen
Xiufu Wu
Li Sun
Sujie Li
Shuyang Wei

Frontiers in Oncology

doi 10.3389/fonc.2025.1662401

790 views

Original Research

Accepted on 24 Nov 2025

Association of Thyroid Disease and Intracranial Meningiomas: A Retrospective Analysis with External Validation

in Neuro-Oncology and Neurosurgical Oncology

Max Andy Saint-Germain
Jonathan B Bell
Carlen A Yuen
Andrew Wilmington
Laura Dresser
Matthew T Walker
Christopher R Trevino
Roberto Salvatori
Debraj Mukherjee
David Olayinka Kamson

Frontiers in Oncology

191 views

Original Research

Published on 24 Nov 2025

The oncometabolite R-2-hydroxyglutarate inhibits microglial activation via the FTO/NF-κB pathway

in Neuro-Oncology and Neurosurgical Oncology

Lu Wang
Huiting Zhang
Xifeng Jing
Yuanchi Huang
Yuxin Kang
Yulan Qian
Dong Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1525761

741 views

Case Report

Published on 21 Nov 2025

Ruptured giant lateral thoracic meningocele associated with intracranial hypotension syndrome in neurofibromatosis type 1: case report with long-term follow-up

in Neuro-Oncology and Neurosurgical Oncology

Wenfu Li
Hui Zhou

Frontiers in Oncology

doi 10.3389/fonc.2025.1662107

576 views

Case Report

Published on 21 Nov 2025

Successful response in advanced leptomeningeal disease from pleomorphic xanthoastrocytoma with BRAF/MEK inhibitors: a case report

in Neuro-Oncology and Neurosurgical Oncology

Maria A. Jacome
Robert J. Macaulay
Edwin Peguero
Sheethal Cyriac
Solmaz Sahebjam
Arnold B. Etame
Hsiang-Hsuan Michael Yu
Yolanda Piña

Frontiers in Oncology

doi 10.3389/fonc.2025.1669942

782 views

Original Research

Published on 20 Nov 2025

Radiomics-based multiple machine learning approaches for investigating medial wall invasion of the cavernous sinus in pituitary adenomas

in Neuro-Oncology and Neurosurgical Oncology

Yuyang Chen
Jiansheng Zhong
Pengwei Hou
Xiaoyu Wang
Jun Li
Ziqi Li
Tianshun Feng
Liangfeng Wei
Yuhui Chen
Shousen Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1706895

697 views

Original Research

Published on 19 Nov 2025

Risk stratification for intracranial infection after high-grade gliomas surgery: a nomogram development and validation study

in Neuro-Oncology and Neurosurgical Oncology

Shichao Liu
Risheng Liang

Frontiers in Oncology

doi 10.3389/fonc.2025.1697966

579 views

Original Research

Published on 18 Nov 2025

How to predict progression-free survival in patients with grade 2 IDH-mutated diffuse gliomas after surgery: a long-term follow-up analysis

in Neuro-Oncology and Neurosurgical Oncology

Marta Aprile
Vincenzo Di Nunno
Lidia Gatto
Alicia Tosoni
Damiano Balestrini
Vania Ramponi
Alfredo Conti
Monica Maffei
Stella Battaglia
Chiara Maria Argento

Frontiers in Oncology

doi 10.3389/fonc.2025.1673285

905 views

1,503 articles

articles

Case Report: A rare case of bone destructive sacrococcygeal chordoma presenting as anal distension

Sialylation-related gene signature predict prognosis and immunotherapy efficacy in low- and high-grade glioma: a PCA-based stratification study

High Intra-tumoral and Serum Matrix Metalloproteinase 9 Levels are Associated with Reduced Survival of Patients with Glioblastoma and Brain Metastases

A Comprehensive Evaluation of MRI-based Radiogenomics and Prognosis Prediction in Glioma

Secondary Exophytic Glioblastoma of the Cerebellopontine Angle: A Case Report and Review of the Literature

ASPHD1 Is a Tumor-Suppressive and Prognostic Marker in Glioma

CD58 reshapes the immunosuppressive microenvironment in gliomas through PD-L1 upregulation

LncRNA ZFHX4-AS1 initiates an oncogenic axis involving a ZFHX4/SOX2 positive feedback loop to accelerate glioma progression

Correction: Case Report: FGFR1 mutation and massive chromosome loss drive malignant transformation of low-grade gliomas

Multiparametric-MRI habitat radiomics analysis for discriminating pathological types of brain metastases

Patient selection and outcome in low-grade glioma surgery

Isoform-specific vs. pan-histone deacetylase inhibition as approaches for countering glioblastoma: an in vitro study

The glioblastoma virome across tumor and extracellular compartments

Multicenter evaluation of preoperative and standalone embolization in meningiomas

Electrophysiology of gliomas: current science, implications, and opportunities

TREATMENT CHALLENGES IN GLIOBLASTOMA – A CASE REPORT

MRI-based radiomic clustering identifies a glioblastoma subtype enriched for neural stemness and proliferative programs

Association of Thyroid Disease and Intracranial Meningiomas: A Retrospective Analysis with External Validation

The oncometabolite R-2-hydroxyglutarate inhibits microglial activation via the FTO/NF-κB pathway

Ruptured giant lateral thoracic meningocele associated with intracranial hypotension syndrome in neurofibromatosis type 1: case report with long-term follow-up

Successful response in advanced leptomeningeal disease from pleomorphic xanthoastrocytoma with BRAF/MEK inhibitors: a case report

Radiomics-based multiple machine learning approaches for investigating medial wall invasion of the cavernous sinus in pituitary adenomas

Risk stratification for intracranial infection after high-grade gliomas surgery: a nomogram development and validation study

How to predict progression-free survival in patients with grade 2 IDH-mutated diffuse gliomas after surgery: a long-term follow-up analysis