Frontiers in Oncology | Neuro-Oncology and Neurosurgical Oncology

Original Research

Published on 23 Sep 2025

XPO1-inhibitor Selinexor induces MGMT expression by activating PKA-CREB signaling in IDH wildtype glioblastoma

in Neuro-Oncology and Neurosurgical Oncology

Josephine A. Mapunda
Yuta Suzuki
Danielle Burgenske
Paul A. Decker
Lin Zhang
Jeanette E. Eckel-Passow
Jann N. Sarkaria
Gaspar J. Kitange

Frontiers in Oncology

doi 10.3389/fonc.2025.1633580

1,962 views
1 citation

Case Report

Published on 22 Sep 2025

Case Report: Hypothalamic demyelinating lesion preceding lymphoma arising outside the central nervous system

in Neuro-Oncology and Neurosurgical Oncology

Narushi Sugii
Hiroyoshi Kino
Tetsu Suzuki
Noriaki Sakamoto
Makoto Shibuya
Ken Akimoto
Masahide Matsuda
Eiichi Ishikawa

Frontiers in Oncology

doi 10.3389/fonc.2025.1553142

1,819 views

Original Research

Published on 22 Sep 2025

Characterization of hypoxia-related molecular clusters and prognostic riskScore for glioma

in Neuro-Oncology and Neurosurgical Oncology

Xiang Fang
Xinhao Wu
Chengran Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1605949

3,186 views

Original Research

Published on 16 Sep 2025

Histopathological grading affects survival in patients with isocitrate dehydrogenase-wildtype gliomas

in Neuro-Oncology and Neurosurgical Oncology

Ziming Hou
Dongyuan Liu
Zhe Hou
Hongbing Zhang
Hao Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1570941

2,680 views

Original Research

Published on 11 Sep 2025

GADD45G as a novel prognostic biomarker and therapeutic target in glioma: integrative analysis of bulk and single-cell RNA sequencing

in Neuro-Oncology and Neurosurgical Oncology

Cong Shen
Haiping Cai
Chengliang Mao
Jiahao Yang
Kai Tang

Frontiers in Oncology

doi 10.3389/fonc.2025.1608710

2,154 views

Review

Published on 11 Sep 2025

Glioma-neuron interactions: insights from neural plasticity

in Neuro-Oncology and Neurosurgical Oncology

Jingyu Feng
Jun Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1661897

2,987 views

Original Research

Published on 10 Sep 2025

Age is not a significant predictor of survival in patients with IDH-wildtype glioblastoma that undergo gross total resection and complete adjuvant chemoradiation

in Neuro-Oncology and Neurosurgical Oncology

Jeffrey W. Cozzens
Noah B. Drewes
Kristin R. Delfino
Kayla L. Chin
Devin V. Amin
Barbara C. Lokaitis
José A. Espinosa
Breck A. Jones
Leslie J. Acakpo-Satchivi
Hayan Dayoub

Frontiers in Oncology

doi 10.3389/fonc.2025.1657867

1,907 views

Mini Review

Published on 10 Sep 2025

Significance of ARID1A in neuroblastoma onset mechanism

in Neuro-Oncology and Neurosurgical Oncology

Duo Jin
Dong Zhang
Qinyu Tang

Frontiers in Oncology

doi 10.3389/fonc.2025.1624561

1,499 views

Original Research

Published on 03 Sep 2025

Complex skull base brain tumor resection: the role of microvascular doppler in surgical precision and outcomes

in Neuro-Oncology and Neurosurgical Oncology

Kecheng Shen
Liang Sun
Weiwei Zhai
Lijuan Kong
Jiandong Zhu
Zhengquan Yu
Jiang Wu

Frontiers in Oncology

doi 10.3389/fonc.2025.1600980

1,282 views

Original Research

Published on 03 Sep 2025

MR radiomics in assessment of consistency of pituitary macroadenoma: can T1-weighted contrast enhanced image improve diagnostic performance of T2-weighted image?

in Neuro-Oncology and Neurosurgical Oncology

Menghong Zou
Hongwei Li
Hongchao Yao
Yang Liu
Jie Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1539432

1,846 views

Original Research

Published on 02 Sep 2025

Correlation between MGMT methylation and the efficacy of bevacizumab in high-grade glioma

in Neuro-Oncology and Neurosurgical Oncology

Chengrui Yan
Xuexue Bai
Chao Wu
Wenbin Ma
Ming Feng

Frontiers in Oncology

doi 10.3389/fonc.2025.1644934

1,151 views

Original Research

Published on 01 Sep 2025

Apparent diffusion coefficient predicts MGMT status in adult-type diffuse gliomas and is correlated with Ki-67 proliferation index

in Neuro-Oncology and Neurosurgical Oncology

Feng-Ying Zhu
Li-Yong Zhuo
Tian-Da Wang
Jia-Ning Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1609562

936 views

Original Research

Published on 29 Aug 2025

Molecular and histopathological landscape of 131 meningiomas: a retrospective institutional study with insights from cIMPACT-NOW

in Neuro-Oncology and Neurosurgical Oncology

Rola H. Ali
Abdulaziz Hassan
Hussain H. Jarkhi
Abdullah Alshawish
Mohamad Almanabri
Obada T. Alhalabi
Ahmad R. Alsaber
Nawal Y. Ali
Ehab Abdelnabi
Eiman M. A. Mohammed

Frontiers in Oncology

doi 10.3389/fonc.2025.1648953

2,377 views

Original Research

Published on 29 Aug 2025

Risk factors and quality of life in adults with dysphagia after posterior skull base surgery: a cross-sectional study

in Neuro-Oncology and Neurosurgical Oncology

Qiao Wang
Shang-Jin Cheng
Dan Duan
Wen-Yao Cui
Wen-Jie Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1582176

1,120 views

Mini Review

Published on 27 Aug 2025

Seq-ing answers: exploring meningioma biology utilizing bulk RNA-seq-based reference landscapes

in Neuro-Oncology and Neurosurgical Oncology

Abigail G. Parrish
Eric C. Holland

Frontiers in Oncology

doi 10.3389/fonc.2025.1631573

2,238 views

Case Report

Published on 27 Aug 2025

Case Report and review of the literature: A rare cut – surgical resection of primary CNS EBV- positive T-cell lymphoma

in Neuro-Oncology and Neurosurgical Oncology

Lykourgos Anastasopoulos
Eirini Charalampopoulou
Theodoros Argyrakos
Fotis Bourlogiannis
Stefanos Korfias

Frontiers in Oncology

doi 10.3389/fonc.2025.1638461

978 views

Original Research

Published on 25 Aug 2025

Predictive role of MGMT and IDH status in the efficacy of bevacizumab for high-grade glioma: a retrospective study

in Neuro-Oncology and Neurosurgical Oncology

Bai Xuexue
Yan Chengrui
Wenbin Ma
Feng Ming
Wu Chao

Frontiers in Oncology

doi 10.3389/fonc.2025.1634892

1,565 views

Original Research

Published on 25 Aug 2025

Radiomics features from the peritumoral region can be associated with the epilepsy status of glioblastoma patients

in Neuro-Oncology and Neurosurgical Oncology

Yeong Chul Yun
Johann M. E. Jende
Katharina Holz
Sabine Wolf
Freya Garhöfer
Anja Hohmann
Philipp Vollmuth
Martin Bendszus
Heinz-Peter Schlemmer
Felix Sahm

Frontiers in Oncology

doi 10.3389/fonc.2025.1587745

1,697 views
1 citation

Original Research

Published on 25 Aug 2025

NFIA-dependent upregulation of SMC4 promotes metastasis and metabolic reprogramming in glioma

in Neuro-Oncology and Neurosurgical Oncology

Guoyin Li
Yukui Zhao
Yubo He
Zhaoqiang Qian
Xiaoyan Li
Zewen Song
Zhiqiang Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1624370

2,227 views

Case Report

Published on 20 Aug 2025

Ischemic stroke of undetermined source as a priming event for brain metastasis: a case report and systematic literature review

in Neuro-Oncology and Neurosurgical Oncology

Paolo Amisano
Antonio Ciacciarelli
Svetlana Lorenzano
Irene Berto
Sara Belcastro
Danilo Toni
Manuela De Michele

Frontiers in Oncology

doi 10.3389/fonc.2025.1638420

2,504 views

Original Research

Published on 19 Aug 2025

Can we predict neurological complications in patients with metastatic spinal tumors?

in Neuro-Oncology and Neurosurgical Oncology

Chul Jung
Hee Tae Shin
Cho Rong Bae
Joon Hee Lee
Jin Hoon Park
Jae-Hwan Cho
Choong Guen Chee
Jae Yong Jeon

Frontiers in Oncology

doi 10.3389/fonc.2025.1625545

1,577 views

Case Report

Published on 19 Aug 2025

Vestibular schwannomas and papilledema without hydrocephalus: a case report

in Neuro-Oncology and Neurosurgical Oncology

Roberto Calderón-Moreno
Noé Pérez Carrillo
José de Jesús Martínez-Manrique

Frontiers in Oncology

doi 10.3389/fonc.2025.1448374

1,476 views

Original Research

Published on 11 Aug 2025

Evaluating treatment strategies and machine learning based treatment recommendation system for elderly patients with high grade gliomas

in Neuro-Oncology and Neurosurgical Oncology

Feiling Xiang
Mengyuan Fu
Xuelian Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1597925

1,724 views

Original Research

Published on 11 Aug 2025

Clinical characteristics and surgical approach for pituitary granular cell tumors: a case series of six patients and literature review

in Neuro-Oncology and Neurosurgical Oncology

Jun Liu
Wenjun Zhang
Qianliang Huang
Xinyun Ye
Guanlin Huang

Frontiers in Oncology

doi 10.3389/fonc.2025.1490783

1,197 views

1,503 articles

articles

XPO1-inhibitor Selinexor induces MGMT expression by activating PKA-CREB signaling in IDH wildtype glioblastoma

Case Report: Hypothalamic demyelinating lesion preceding lymphoma arising outside the central nervous system

Characterization of hypoxia-related molecular clusters and prognostic riskScore for glioma

Histopathological grading affects survival in patients with isocitrate dehydrogenase-wildtype gliomas

GADD45G as a novel prognostic biomarker and therapeutic target in glioma: integrative analysis of bulk and single-cell RNA sequencing

Glioma-neuron interactions: insights from neural plasticity

Age is not a significant predictor of survival in patients with IDH-wildtype glioblastoma that undergo gross total resection and complete adjuvant chemoradiation

Significance of ARID1A in neuroblastoma onset mechanism

Complex skull base brain tumor resection: the role of microvascular doppler in surgical precision and outcomes

MR radiomics in assessment of consistency of pituitary macroadenoma: can T1-weighted contrast enhanced image improve diagnostic performance of T2-weighted image?

Correlation between MGMT methylation and the efficacy of bevacizumab in high-grade glioma

Apparent diffusion coefficient predicts MGMT status in adult-type diffuse gliomas and is correlated with Ki-67 proliferation index

Molecular and histopathological landscape of 131 meningiomas: a retrospective institutional study with insights from cIMPACT-NOW

Risk factors and quality of life in adults with dysphagia after posterior skull base surgery: a cross-sectional study

Seq-ing answers: exploring meningioma biology utilizing bulk RNA-seq-based reference landscapes

Case Report and review of the literature: A rare cut – surgical resection of primary CNS EBV- positive T-cell lymphoma

Predictive role of MGMT and IDH status in the efficacy of bevacizumab for high-grade glioma: a retrospective study

Radiomics features from the peritumoral region can be associated with the epilepsy status of glioblastoma patients

NFIA-dependent upregulation of SMC4 promotes metastasis and metabolic reprogramming in glioma

Ischemic stroke of undetermined source as a priming event for brain metastasis: a case report and systematic literature review

Can we predict neurological complications in patients with metastatic spinal tumors?

Vestibular schwannomas and papilledema without hydrocephalus: a case report

Evaluating treatment strategies and machine learning based treatment recommendation system for elderly patients with high grade gliomas

Clinical characteristics and surgical approach for pituitary granular cell tumors: a case series of six patients and literature review