Frontiers in Oncology | Thoracic Oncology

Original Research

Accepted on 30 Dec 2025

Factors associated with longer brain metastasis-free survival in limited-disease small-cell lung cancer who underwent concurrent chemoradiotherapy,a retrospective analysis

in Thoracic Oncology

Xiang-Rong Zhao
Yong-Hua Yu
Chao Gao

Frontiers in Oncology

Case Report

Accepted on 30 Dec 2025

Exceptional Long-term Survival in an Adult with Advanced Classic Biphasic Pulmonary Blastoma: A Case Report and Literature Review

in Thoracic Oncology

Jun Li
Si Chen
Qiliang Liu
Ming Li

Frontiers in Oncology

Original Research

Accepted on 29 Dec 2025

CYP4B1 Inhibits Lung Adenocarcinoma Progression via PI3K/AKT/mTOR Pathway: Mechanistic Insights and Development of a CYP4B1-Related Prognostic Signature

in Thoracic Oncology

Guoyin Li
Jing Kang
Xiaoyan Li
Liping Zhao
Yuhang Chen
Chenlu Gong
Zhiqiang Liu
Bi Zhang

Frontiers in Oncology

148 views

Original Research

Accepted on 29 Dec 2025

Assessing Venous Thromboembolism Risk in Lung Cancer: A Comprehensive Evaluation of the Khorana Score, Clinical Characteristics, and Incidence of Thrombosis

in Thoracic Oncology

Sean Dougherty
Rishika Singh
Caleb McKinney
Aditya Singh
Jack Masur
Alia C Lynch
Ryan D Gentzler
Wendy Novicoff
Nathan Roberts
Richard Hall

Frontiers in Oncology

Original Research

Accepted on 29 Dec 2025

BUB1 Promotes Lung Adenocarcinoma Progression by Regulating STAT3/GPX4-Mediated Ferroptosis

in Thoracic Oncology

Xiaocong Mo
Ying Liu
Yu Wang
Xiaofen Pan
Mengyuan Zhu
Jiehao Liao
Minling Liu
Tingwei Li
Xueying Li
Shuo Fang

Frontiers in Oncology

101 views

Original Research

Accepted on 29 Dec 2025

The Concurrence of Lung Malignancies and Organizing Pneumonia

in Thoracic Oncology

Srikanth Vedachalam
Mohammad Freihat
Ahmed Alomari
Catherine Rufatto Sears
Nawar Al Nasrallah

Frontiers in Oncology

Original Research

Accepted on 29 Dec 2025

The modified Glasgow Prognostic Score (mGPS) serves as a robust predictor of unplanned readmission and 1-year mortality in lung cancer patients receiving immune checkpoint inhibitors

in Thoracic Oncology

Bo Deng
Fengwang Xue
Ruoqing Lu
Cailian, Wang
Qilian, Xiong
Ying Liu
Shengmin Guo

Frontiers in Oncology

Original Research

Accepted on 29 Dec 2025

Impact of Smoking on Immune Feature and Prognosis in Unresectable Stage III Anaplastic Lymphoma Kinase Positive Non-Small-Cell Lung Cancer

in Thoracic Oncology

Ying Jiang
Zhihui Zhang
Jianzhong Cao
Jianchun Duan
Tao Zhang
Yu Wang
Weihua Li
Fengwei Tan
Jianming Ying
Nan Bi

Frontiers in Oncology

Case Report

Accepted on 26 Dec 2025

Long-Term Survival in Extensive-Stage Small Cell Lung Cancer: A Case Report on the Integration of Interventional Bronchoscopy and Systemic Immunotherapy

in Thoracic Oncology

Deng Ganxiu
Yan Shixuan
VICTOR BWEMBYA
Xiaoping Zhu
Luo Zhibing
Changwen Deng

Frontiers in Oncology

Systematic Review

Accepted on 24 Dec 2025

Comparison of the efficacy based on clinicopathological characteristics and the safety of first-line treatments for patients with advanced ALK rearrangement non-small cell lung cancer: A network meta-analysis

in Thoracic Oncology

Yanwei Li
Yunxin Wen
Wenjing Zhang
Yurong Zhao
Ligui Zhou
Xianrong Zeng
Xuefeng Kang
Luzhen Li

Frontiers in Oncology

Original Research

Accepted on 24 Dec 2025

MTPC Integration for Improved Diagnosis of Pleural Effusion

in Thoracic Oncology

Shuai Zhao
Jiajia Liu
Jing Chen
Ji Shi
Ming Ma
Haiyang Yan
Jingna Sun
Yan Geng

Frontiers in Oncology

Editorial

Accepted on 23 Dec 2025

Editorial: Biomarker-Guided Strategies in NSCLC Immunotherapy

in Thoracic Oncology

Myrto K. Moutafi
Kok Haw Jonathan Lim
Panagiota Economopoulou
Ioannis Mountzios

Frontiers in Oncology

171 views

Case Report

Accepted on 23 Dec 2025

Triple-Positive Non-Small Cell Lung Cancer Harboring EGFR Mutation, ALK Rearrangement, and High PD-L1 Expression: A Case Report and Literature Review

in Thoracic Oncology

Mengjie Mao
Qingxiu Tao
Zhuo Zuo
Jun Ge
Yuke Tian
Bin Liu

Frontiers in Oncology

191 views

Original Research

Accepted on 22 Dec 2025

Translational Impact of Machine Learning-Driven Predictive Modeling with Pathway-Based Plasma Metabolomic Biomarkers for Lung Cancer Detection

in Thoracic Oncology

Eyad Himdiat
Jean-Françoise Haince
Rashid A. Bux
Guoyu Huang
Paramjit S Tappia
Bram Ramjiawan
MARIA VAIDA

Frontiers in Oncology

134 views

Original Research

Accepted on 22 Dec 2025

Common laboratory parameters as predictors of prognosis in primary lung cancer

in Thoracic Oncology

Mingchun Cai
Hao Chen
Zhengbo Yan
Xuehua He

Frontiers in Oncology

Systematic Review

Accepted on 22 Dec 2025

Comparative efficacy of trastuzumab deruxtecan versus guideline-recommended treatments for 2L+ unresectable locally advanced or metastatic HER2-mutant non-small cell lung cancer: a systematic review and indirect treatment comparison

in Thoracic Oncology

Federico Cappuzzo
Lirong Zhang
Kyle Dunton
Natalie Dennis
Pauline Le Nouveau
Agathe Nevière
Aline Gauthier

Frontiers in Oncology

144 views

Study Protocol

Accepted on 22 Dec 2025

TROPION-Lung10: a phase 3 study of datopotamab deruxtecan and rilvegostomig in patients with treatment-naïve locally advanced or metastatic nonsquamous non-small cell lung cancer with high PD-L1 expression and without actionable genomic alterations

in Thoracic Oncology

Tom Newsom-Davis
Barbara Melosky
Rebecca S Heist
Shun Lu
Giulia Pasello
Xiwei Chen
Marta Stachowiak
Pavlo Lyfar
Alessandra Forcina
Suresh S Ramalingam

Frontiers in Oncology

206 views

Original Research

Accepted on 19 Dec 2025

LungPanelNet: A Machine Learning-Based Approach for the Early Prediction and Differentiation of Non-Small Cell Lung Cancer

in Thoracic Oncology

Li Zhao
Mei LI
Juju Qi
Lingling Wan

Frontiers in Oncology

211 views

Correction

Published on 19 Dec 2025

Correction: STRA6 polymorphisms are associated with EGFR mutations in locally-advanced and metastatic non-small cell lung cancer patients

in Thoracic Oncology

Saé Muñiz-Hernández
Jesús Bernardino Velázquez-Fernández
José Díaz-Chávez
Omar Mondragón-Fonseca
Yerye Mayén-Lobo
Alberto Ortega
Marisol López-López
Oscar Arrieta

Frontiers in Oncology

doi 10.3389/fonc.2025.1760931

363 views

Original Research

Published on 19 Dec 2025

Radiomic approach to support multidisciplinary tumor board decision-making in locally advanced non-small cell lung cancer

in Thoracic Oncology

Giulia Pasello
Harel Kotler
Alessandra Ferro
Luca Bergamin
Elena Scagliori
Angela Grassi
Fabio Aiolli
Mattia De Nuzzo
Marco Schiavon
Matteo Sepulcri

Frontiers in Oncology

doi 10.3389/fonc.2025.1713847

545 views

Original Research

Published on 19 Dec 2025

Early prediction of immunotherapy efficacy for advanced NSCLC based on clinical and pre-treatment contrast-enhanced CT radiomics features

in Thoracic Oncology

Yue Hou
Tianming Zhang
Kaibo Zhu
Jing Jiang
Hong Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1711402

673 views

Case Report

Accepted on 18 Dec 2025

Case report: Unraveling a Web of Clots: Marantic Endocarditis as a Paraneoplastic Manifestation of Lung Cancer

in Thoracic Oncology

Bart Forier
Frederik Staels
Dorian Bivort
Mike Ralki

Frontiers in Oncology

105 views

Systematic Review

Published on 18 Dec 2025

Mapping three decades of air pollution–lung cancer research: trends, hotspots, and networks (1990-2025)

in Thoracic Oncology

Haixia Fan
Limantian Wang
Lu Zhai
Shudan Deng
Yan Li
Huiyan Niu
Bomeng Zhao
Jie Gao
Xiaoling Gao

Frontiers in Oncology

doi 10.3389/fonc.2025.1698246

444 views

Case Report

Published on 18 Dec 2025

Ivonescimab combined with chemotherapy shows promising efficacy in an ALK fusion-positive lung adenocarcinoma patient with ALK-TKI resistance: a case report

in Thoracic Oncology

Meiyuan Lin
Yuan Gao
Jun Deng

Frontiers in Oncology

doi 10.3389/fonc.2025.1723763

680 views

1,929 articles

articles

Factors associated with longer brain metastasis-free survival in limited-disease small-cell lung cancer who underwent concurrent chemoradiotherapy,a retrospective analysis

Exceptional Long-term Survival in an Adult with Advanced Classic Biphasic Pulmonary Blastoma: A Case Report and Literature Review

CYP4B1 Inhibits Lung Adenocarcinoma Progression via PI3K/AKT/mTOR Pathway: Mechanistic Insights and Development of a CYP4B1-Related Prognostic Signature

Assessing Venous Thromboembolism Risk in Lung Cancer: A Comprehensive Evaluation of the Khorana Score, Clinical Characteristics, and Incidence of Thrombosis

BUB1 Promotes Lung Adenocarcinoma Progression by Regulating STAT3/GPX4-Mediated Ferroptosis

The Concurrence of Lung Malignancies and Organizing Pneumonia

The modified Glasgow Prognostic Score (mGPS) serves as a robust predictor of unplanned readmission and 1-year mortality in lung cancer patients receiving immune checkpoint inhibitors

Impact of Smoking on Immune Feature and Prognosis in Unresectable Stage III Anaplastic Lymphoma Kinase Positive Non-Small-Cell Lung Cancer

Long-Term Survival in Extensive-Stage Small Cell Lung Cancer: A Case Report on the Integration of Interventional Bronchoscopy and Systemic Immunotherapy

Comparison of the efficacy based on clinicopathological characteristics and the safety of first-line treatments for patients with advanced ALK rearrangement non-small cell lung cancer: A network meta-analysis

MTPC Integration for Improved Diagnosis of Pleural Effusion

Editorial: Biomarker-Guided Strategies in NSCLC Immunotherapy

Triple-Positive Non-Small Cell Lung Cancer Harboring EGFR Mutation, ALK Rearrangement, and High PD-L1 Expression: A Case Report and Literature Review

Translational Impact of Machine Learning-Driven Predictive Modeling with Pathway-Based Plasma Metabolomic Biomarkers for Lung Cancer Detection

Common laboratory parameters as predictors of prognosis in primary lung cancer

Comparative efficacy of trastuzumab deruxtecan versus guideline-recommended treatments for 2L+ unresectable locally advanced or metastatic HER2-mutant non-small cell lung cancer: a systematic review and indirect treatment comparison

TROPION-Lung10: a phase 3 study of datopotamab deruxtecan and rilvegostomig in patients with treatment-naïve locally advanced or metastatic nonsquamous non-small cell lung cancer with high PD-L1 expression and without actionable genomic alterations

LungPanelNet: A Machine Learning-Based Approach for the Early Prediction and Differentiation of Non-Small Cell Lung Cancer

Correction: STRA6 polymorphisms are associated with EGFR mutations in locally-advanced and metastatic non-small cell lung cancer patients

Radiomic approach to support multidisciplinary tumor board decision-making in locally advanced non-small cell lung cancer

Early prediction of immunotherapy efficacy for advanced NSCLC based on clinical and pre-treatment contrast-enhanced CT radiomics features

Case report: Unraveling a Web of Clots: Marantic Endocarditis as a Paraneoplastic Manifestation of Lung Cancer

Mapping three decades of air pollution–lung cancer research: trends, hotspots, and networks (1990-2025)

Ivonescimab combined with chemotherapy shows promising efficacy in an ALK fusion-positive lung adenocarcinoma patient with ALK-TKI resistance: a case report