Frontiers in Oncology | Thoracic Oncology

Case Report

Published on 06 Nov 2025

Case Report: Pitfalls in anatomic pathology and clinical oncology: a case of misdiagnosed pulmonary Ewing sarcoma as SCLC

in Thoracic Oncology

Nagham S. El Waary
Angelo A. Chami
Jawad K. Zrein
Doha A. Houcheimy
Ryan T. Akl
Siham D. Fleifel
Francois G. Kamar

Frontiers in Oncology

doi 10.3389/fonc.2025.1635424

1,331 views

Original Research

Published on 04 Nov 2025

MiR-4664-3p as a potential diagnostic, prognostic, and immunotherapeutic biomarker in NSCLC: modulation of tumor progression through CD8 + T cell regulation

in Thoracic Oncology

Chun Yi
Hao Zhang
Qianqian Guo
Linzhu Lu
Cong Gao
Yunlong Zhao
Yan Su
Jing Lu

Frontiers in Oncology

doi 10.3389/fonc.2025.1642999

1,137 views

Original Research

Published on 31 Oct 2025

To predict the spread through air spaces in lung adenocarcinoma using radiomic features from different regions of part-solid nodules: a multicenter study

in Thoracic Oncology

Shiyu Cui
Hongzheng Song
Fanxia Lin
Xiaomeng Han
Bo Wang
Liang Zhang
Feng Hou
Enhao Kang
Jizheng Lin
Henan Lou

Frontiers in Oncology

doi 10.3389/fonc.2025.1700843

1,150 views

Original Research

Published on 31 Oct 2025

Preoperative plasma fibrinogen combined with the platelet-to-lymphocyte ratio (F-PLR) serves as a prognostic indicator in patients with non-small cell lung cancer

in Thoracic Oncology

Hongzhen Zhao
Xiaopeng Zhang
Dahu Ren
Shicheng Liu
Yuedong Wang
Wenbo Wu
Kun Zhang
Yajing Niu
Guochen Duan

Frontiers in Oncology

doi 10.3389/fonc.2025.1587443

888 views

Original Research

Published on 30 Oct 2025

Predicting EGFR gene mutation in lung adenocarcinoma using spectral CT combined with AI parameters: a diagnostic accuracy study

in Thoracic Oncology

Lilan She
Min Xie
Guolin Xu
Xiangmei Zhan
Meilan Huang
Yunjing Xue

Frontiers in Oncology

doi 10.3389/fonc.2025.1611759

1,644 views

Original Research

Published on 29 Oct 2025

Fusion of CT radiomics and autoantibody biomarkers for enhanced prediction of lung cancer diagnosis: a comprehensive study

in Thoracic Oncology

Xianwu Xia
Jinshuo Liu
Yiman Du
Xiaowen Ma
Guoming Zhou
Jianjun Yuan
Qianjin Hua
Lingling Wang
Haitao Jiang
Caidi He

Frontiers in Oncology

doi 10.3389/fonc.2025.1591156

1,371 views

Original Research

Published on 29 Oct 2025

Development and validation of machine learning models for predicting STAS in stage I lung adenocarcinoma with part-solid and solid nodules: a two-center study

in Thoracic Oncology

Qing-Lin Ren
Liu Lin
Kai Chu
Xin-Rong Xu
Hui-Jun Wang
Jun Wu
Jin-Zhi You
Jun-Xi Hu
Xiao-Lin Wang
Yu-Sheng Shu

Frontiers in Oncology

doi 10.3389/fonc.2025.1682633

1,165 views

Case Report

Published on 28 Oct 2025

Long-term survival following multimodal therapy for lung cancer with hepatic metastasis: a case report

in Thoracic Oncology

Zhao Junjun
Zhang Jiandong
Dong Lingjun
Yu Guangmao
Zhang Chu

Frontiers in Oncology

doi 10.3389/fonc.2025.1663079

1,666 views

Case Report

Published on 27 Oct 2025

Case Report: Evolution and targeted therapy of an EGFR-mutant large-cell neuroendocrine carcinoma

in Thoracic Oncology

Li Jiang
Xiaowen Yao
Xiuyu Cai
Pengfei Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1599765

1,749 views
1 citation

Original Research

Published on 27 Oct 2025

Preoperative absolute neutrophil count: a potential indicator for prognosis in carcinoembryonic antigen normal stage I non-small cell lung cancer

in Thoracic Oncology

Bailin Wang
Long Liu
Meiqi Cui
Qianwen Ye
Panhua Li
Bing Yan

Frontiers in Oncology

doi 10.3389/fonc.2025.1632597

862 views

Original Research

Published on 27 Oct 2025

Conformal sublobar electroresection with volume optimization achieves greater parenchymal preservation than stapler in wedge resection: a volumetric analysis

in Thoracic Oncology

Xining Zhang
JingWei Liu
ShiJie Zhang
Jian Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1657405

856 views

Brief Research Report

Published on 27 Oct 2025

Impact of prior immunotherapy on paclitaxel/bevacizumab in advanced non-squamous non-small cell lung cancer

in Thoracic Oncology

Agathe Peyret
Clémentine Le Berrurier
Luc Heraudet
Tara Delon
Maéva Zysman
Mathieu Larroquette
Laura Leroy
Sophie Cousin
Charlotte Domblides

Frontiers in Oncology

doi 10.3389/fonc.2025.1675386

1,520 views

Review

Published on 27 Oct 2025

A comparison of clinical guidelines, treatment characteristics and outcomes in small cell lung cancer between East Asia and Europe/North America

in Thoracic Oncology

Chi-Lu Chiang
Ross Andrew Soo
Tony Mok
Pei Jye Voon
Lucksamon Thamlikitkul
Ying Cheng
Hidehito Horinouchi
Byong Chul Cho
Krista Lin Xu
Myung-Ju Ahn

Frontiers in Oncology

doi 10.3389/fonc.2025.1646608

3,020 views

Review

Published on 23 Oct 2025

Advances in modelling the risk of benign and malignant lung nodules

in Thoracic Oncology

Shang Du
Tangwei Wu
Hui Wang
Zheqiong Tan
Zhongxin Lu

Frontiers in Oncology

doi 10.3389/fonc.2025.1648548

1,492 views

Original Research

Published on 23 Oct 2025

Real-world survival patterns and multimodal therapy utilization in small cell lung cancer: a retrospective cohort study in a Chinese countryside hospital

in Thoracic Oncology

Taosheng Huang
Linjie Ma
Mingfang Wang
Xumei Pang
Jiying Xu
Xi Chen
Yutao Xia
Min Yan
Wenxiang Zhao
Congcong Cheng

Frontiers in Oncology

doi 10.3389/fonc.2025.1636533

1,661 views

Original Research

Published on 22 Oct 2025

Blood-based tumor mutational burden as a biomarker in unresectable non-small cell lung cancer treated with chemoradiotherapy and durvalumab

in Thoracic Oncology

Henrik Horndalsveen
Vilde Drageset Haakensen
Tesfaye Madebo
Bjørn Henning Grønberg
Tarje Onsøien Halvorsen
Jussi Koivunen
Kersti Oselin
Saulius Cicenas
Nina Helbekkmo
Marianne Aanerud

Frontiers in Oncology

doi 10.3389/fonc.2025.1681420

3,262 views
1 citation

Original Research

Published on 22 Oct 2025

Durvalumab following definitive chemoradiotherapy among patients with stage III NSCLC in the Thai population: a real-world, multicenter observational study

in Thoracic Oncology

Piyada Sitthideatphaiboon
Thanyanan Reungwetwattana
Sureerat Jaruhathai
Archara Supavavej
Piyarat Limpawittayakul
Kunlatida Maneenil
Krittiya Korphaisarn
Thatthan Suksombooncharoen
Luangyot Thongthieang
Chirawadee Sathitruangsak

Frontiers in Oncology

doi 10.3389/fonc.2025.1647385

1,616 views

Case Report

Published on 22 Oct 2025

Case Report: Analysis of short-term clinical efficacy of trilaciclib in patients with advanced lung neuroendocrine carcinoma undergoing chemotherapy

in Thoracic Oncology

Yan Zeng
Nan Lin

Frontiers in Oncology

doi 10.3389/fonc.2025.1685910

1,386 views

Case Report

Published on 22 Oct 2025

Primary leiomyosarcoma originating from the azygos vein misdiagnosed as tracheal tumor: a case report and literature review

in Thoracic Oncology

Long-fei Zhu
Yu-jun Wang
Chun-jian Zuo
Yuan-lin Deng
Bin Jiang

Frontiers in Oncology

doi 10.3389/fonc.2025.1639131

825 views

General Commentary

Accepted on 21 Oct 2025

Commentary: CT-based radiomics integrated model for brain metastases in stage III/IV ALK-positive lung adenocarcinoma patients

in Thoracic Oncology

Yun Qiao
Nan Wang

Frontiers in Oncology

391 views

Original Research

Published on 21 Oct 2025

Hsp70 regulates CD24 expression and promotes metastasis and invasion of lung cancer via the MAPK/ERK signaling pathway

in Thoracic Oncology

Xin Liu
Xinjing Yu
Qun Hu
Ning Zhang
Shuyu Zhang
Yang Liu
Jiaqi Jia
Xiaojuan Qiao

Frontiers in Oncology

doi 10.3389/fonc.2025.1665342

1,286 views

Review

Published on 20 Oct 2025

Evaluating the combined efficacy of Telisotuzumab Vedotin and artificial intelligence in the treatment of non-squamous non-small cell lung cancer: a narrative review focusing on pharmaceutical and technical insights

in Thoracic Oncology

Syeda Huda Fatima
Syeda Jazilah Faisal
Syeda Verisha Batool
Mehak Faisal
Talha Aamir
Zain Ul Abideen Shahid
Raghabendra Kumar Mahato

Frontiers in Oncology

doi 10.3389/fonc.2025.1673586

3,428 views

Case Report

Published on 20 Oct 2025

Different therapeutic responses to osimertinib as first-line treatment for cavitated and non-cavitated squamous cell lung cancer with rare EGFR exon 19 deletion: two case reports and a literature review

in Thoracic Oncology

Jing Ren
Liang Xiao Cheng
Rui Zhang
Zhi Zou
Yongzhao Zhou
Xi Zheng

Frontiers in Oncology

doi 10.3389/fonc.2025.1626665

1,692 views

Original Research

Published on 17 Oct 2025

Marked under-diagnosis of Lambert-Eaton myasthenic syndrome in small cell lung cancer: an analysis of real-world claims data

in Thoracic Oncology

Benjamin J. Drapkin
David J. Morrell
Regina Grebla
Guy Shechter
David E. Gerber

Frontiers in Oncology

doi 10.3389/fonc.2025.1650373

2,479 views

1,969 articles

articles

Case Report: Pitfalls in anatomic pathology and clinical oncology: a case of misdiagnosed pulmonary Ewing sarcoma as SCLC

MiR-4664-3p as a potential diagnostic, prognostic, and immunotherapeutic biomarker in NSCLC: modulation of tumor progression through CD8 + T cell regulation

To predict the spread through air spaces in lung adenocarcinoma using radiomic features from different regions of part-solid nodules: a multicenter study

Preoperative plasma fibrinogen combined with the platelet-to-lymphocyte ratio (F-PLR) serves as a prognostic indicator in patients with non-small cell lung cancer

Predicting EGFR gene mutation in lung adenocarcinoma using spectral CT combined with AI parameters: a diagnostic accuracy study

Fusion of CT radiomics and autoantibody biomarkers for enhanced prediction of lung cancer diagnosis: a comprehensive study

Development and validation of machine learning models for predicting STAS in stage I lung adenocarcinoma with part-solid and solid nodules: a two-center study

Long-term survival following multimodal therapy for lung cancer with hepatic metastasis: a case report

Case Report: Evolution and targeted therapy of an EGFR-mutant large-cell neuroendocrine carcinoma

Preoperative absolute neutrophil count: a potential indicator for prognosis in carcinoembryonic antigen normal stage I non-small cell lung cancer

Conformal sublobar electroresection with volume optimization achieves greater parenchymal preservation than stapler in wedge resection: a volumetric analysis

Impact of prior immunotherapy on paclitaxel/bevacizumab in advanced non-squamous non-small cell lung cancer

A comparison of clinical guidelines, treatment characteristics and outcomes in small cell lung cancer between East Asia and Europe/North America

Advances in modelling the risk of benign and malignant lung nodules

Real-world survival patterns and multimodal therapy utilization in small cell lung cancer: a retrospective cohort study in a Chinese countryside hospital

Blood-based tumor mutational burden as a biomarker in unresectable non-small cell lung cancer treated with chemoradiotherapy and durvalumab

Durvalumab following definitive chemoradiotherapy among patients with stage III NSCLC in the Thai population: a real-world, multicenter observational study

Case Report: Analysis of short-term clinical efficacy of trilaciclib in patients with advanced lung neuroendocrine carcinoma undergoing chemotherapy

Primary leiomyosarcoma originating from the azygos vein misdiagnosed as tracheal tumor: a case report and literature review

Commentary: CT-based radiomics integrated model for brain metastases in stage III/IV ALK-positive lung adenocarcinoma patients

Hsp70 regulates CD24 expression and promotes metastasis and invasion of lung cancer via the MAPK/ERK signaling pathway

Evaluating the combined efficacy of Telisotuzumab Vedotin and artificial intelligence in the treatment of non-squamous non-small cell lung cancer: a narrative review focusing on pharmaceutical and technical insights

Different therapeutic responses to osimertinib as first-line treatment for cavitated and non-cavitated squamous cell lung cancer with rare EGFR exon 19 deletion: two case reports and a literature review

Marked under-diagnosis of Lambert-Eaton myasthenic syndrome in small cell lung cancer: an analysis of real-world claims data