Frontiers in Oncology

Case Report

Published on 15 Aug 2025

A non-small cell lung cancer fragile elderly patient treated with immunotherapy and non-ablative radiation therapy: a case report of a winning combination

Jessica Saddi
David Alberto Santos Hernandez
Giulia Maria Stella
Giulia Galli
Sabrina Borgetto
Elisabetta Bonzano
Andrea Lancia
Salvatore La Mattina
Sara Colombo
Luigi Squillace

Frontiers in Oncology

doi 10.3389/fonc.2025.1642564

454 views

Case Report

Published on 15 Aug 2025

Safety and clinical efficacy of immune checkpoint inhibitors in pediatric hepatocellular carcinoma: a case report and review of the literature

Xiaoting Zhong
Xuejiao Wen
Xinping Wang
Jianming Ye
Li Huang
Jing Wang
Jun Chi
Xiaoli Zeng

Frontiers in Oncology

doi 10.3389/fonc.2025.1576892

335 views

Systematic Review

Published on 15 Aug 2025

Real-world effectiveness and safety of CDK4/6i in elderly and BIPOC patients with HR+/HER2- advanced/metastatic breast cancer: an updated systematic literature review

Nadia Harbeck
Adam Brufsky
Chloe Grace Rose
Beata Korytowsky
Connie Chen
Krista Tantakoun
Endri Jazexhi
Do Hoang Vien Nguyen
Meaghan Bartlett
Imtiaz A. Samjoo

Frontiers in Oncology

doi 10.3389/fonc.2025.1577075

440 views

Original Research

Published on 15 Aug 2025

Linoleic acid drives pulmonary lymphoepithelioma-like carcinoma progression via PPAR-α/TF axis

Hejing Bao
Jiani Zhang
Zhuoyan Chen
Yuhuan Wang
Zhe Wang
Zhiting Chen
Ting Jiang
Baishen Zhang
Wen Zeng
Hehong Bao

Frontiers in Oncology

doi 10.3389/fonc.2025.1640201

315 views

Review

Published on 15 Aug 2025

Open partial or transoral laryngectomy – total laryngectomy today

Dietmar Thurnher
Ricard Simo
Giovanni Succo
Isabel Vilaseca
Christian Simon

Frontiers in Oncology

doi 10.3389/fonc.2025.1520524

367 views

Case Report

Published on 15 Aug 2025

Gastric fundus leiomyoma: a rare case report

Kaiyuan Luo
Jianfeng Bin
Jun Bian
Haomin Wang
Dai Tang
Maozhao Yan
Hua Ge

Frontiers in Oncology

doi 10.3389/fonc.2025.1652318

236 views

Original Research

Published on 15 Aug 2025

Broad-spectrum antitumor analysis of the telomerase activity inhibitor TPCH derived from the human constitutively expressed protein LPTS/PinX1

Hongchang Zhou
Xiaoying Zhang
Yao Wang
Yongqiang Wu
Ling Wang
Chen Hu
Ting Zhang
Hui Zhang
Dian You
Mengli Zhao

Frontiers in Oncology

doi 10.3389/fonc.2025.1643155

266 views

Mini Review

Published on 15 Aug 2025

Small cell carcinoma of the ovary, hypercalcemic type: a mini review

Marta Tripepi
Ana G. da Costa
Dennis S. Chi
Jorge Lima
João Casanova

Frontiers in Oncology

doi 10.3389/fonc.2025.1645361

361 views

Original Research

Published on 15 Aug 2025

Treatment outcomes of squamous cell carcinoma of the external auditory canal and potential benefit of induction chemotherapy followed by chemoradiotherapy

Yosuke Mizunari
Masato Nagaoka
Naohiro Takeshita
Kazuki Kanno
Haruyuki Hirayama
Taisuke Akutsu
Hisashi Kessoku
Katsuhiro Ishida
Yutaka Yamamoto

Frontiers in Oncology

doi 10.3389/fonc.2025.1530922

303 views

Original Research

Accepted on 14 Aug 2025

NK Cell-Related Genes-Driven Novel Molecular Subtyping and Prognostic Signatures for Wilms Tumor: Uncovering the Therapeutic Potential of TGX-221 and Biomarker Role of HS2ST1

Peng Hong
Hong Zai Hu
Jie Lin
Kongkong Cui
Qiang Zhi Gao
Xiao-Mao Tian
Tao Lin
Qinlin Shi
Hui Guang Wei

Frontiers in Oncology

doi 10.3389/fonc.2025.1593011

125 views

Case Report

Accepted on 14 Aug 2025

Erdheim-Chester Disease: Unveiling Hidden Manifestations through Two Case Reports

GuoXia Zhang
Xiaoqing Yang
Lei Fang
Yuxia Cheng
Yanhua Duan
Jing Cui

Frontiers in Oncology

doi 10.3389/fonc.2025.1611907

Original Research

Accepted on 14 Aug 2025

Development and Evaluation of a Clinical-Biochemical Nomogram for Differentiating Pleomorphic Adenoma and Warthin's Tumor in the Parotid Gland

Xiaoying Huang
Feng Zhao
Junkun He
Jiping Su
Zhe Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1565727

Case Report

Accepted on 14 Aug 2025

PEComa Progressed by mTOR Inhibitor Therapy with Anti-VEGFR TKI Combined with PD-1 Inhibitor：a case report

Guannan Wang
Lili Sun
Jian Guan
Boyan Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1628650

102 views

Original Research

Accepted on 14 Aug 2025

Evaluation of anti-liver cancer activity and anticancer mechanism of one novel small molecule compound (THY-10A62) targeting FAK pathway

Wanqiu Huang
Rong Zou
Jie Xu
Yuliang Deng
Dongping Zhang
Yiguo Hu
Qian Zhang
Jian Huang
Zhaoqi Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1498005

Original Research

Accepted on 14 Aug 2025

Telemedicine-Based Adapted Physical Activity Programs for Pediatric Oncology Patients in Active Oncological Care: A Feasibility Study

Linda Peli
Elisa Inselvini
Marta Cogliati
Eleonora Finazzi
Chiara Gorio
Alessia Angeloni
Joel Pollet
Richard Fabian Schumacher
Fulvio Porta
Filippo Bertoni

Frontiers in Oncology

doi 10.3389/fonc.2025.1634626

Original Research

Accepted on 14 Aug 2025

Novel perceptions of the involvement of CPZ in gastric cancer prognosis and immunomodulation

Zhenmin Yuan
Xiaoying Yang
Junjie Huang
Junren Wei
Lei Tian

Frontiers in Oncology

doi 10.3389/fonc.2025.1599542

108 views

32,350 Publications

Volume 15 - 2025

A non-small cell lung cancer fragile elderly patient treated with immunotherapy and non-ablative radiation therapy: a case report of a winning combination

Safety and clinical efficacy of immune checkpoint inhibitors in pediatric hepatocellular carcinoma: a case report and review of the literature

Real-world effectiveness and safety of CDK4/6i in elderly and BIPOC patients with HR+/HER2- advanced/metastatic breast cancer: an updated systematic literature review

Linoleic acid drives pulmonary lymphoepithelioma-like carcinoma progression via PPAR-α/TF axis

Open partial or transoral laryngectomy – total laryngectomy today

Gastric fundus leiomyoma: a rare case report

Broad-spectrum antitumor analysis of the telomerase activity inhibitor TPCH derived from the human constitutively expressed protein LPTS/PinX1

Small cell carcinoma of the ovary, hypercalcemic type: a mini review

Treatment outcomes of squamous cell carcinoma of the external auditory canal and potential benefit of induction chemotherapy followed by chemoradiotherapy

NK Cell-Related Genes-Driven Novel Molecular Subtyping and Prognostic Signatures for Wilms Tumor: Uncovering the Therapeutic Potential of TGX-221 and Biomarker Role of HS2ST1

Erdheim-Chester Disease: Unveiling Hidden Manifestations through Two Case Reports

Development and Evaluation of a Clinical-Biochemical Nomogram for Differentiating Pleomorphic Adenoma and Warthin's Tumor in the Parotid Gland

PEComa Progressed by mTOR Inhibitor Therapy with Anti-VEGFR TKI Combined with PD-1 Inhibitor：a case report

Evaluation of anti-liver cancer activity and anticancer mechanism of one novel small molecule compound (THY-10A62) targeting FAK pathway

Telemedicine-Based Adapted Physical Activity Programs for Pediatric Oncology Patients in Active Oncological Care: A Feasibility Study

Novel perceptions of the involvement of CPZ in gastric cancer prognosis and immunomodulation