Frontiers in Pain Research | Non-Pharmacological Treatment of Pain

Original Research

Published on 29 Sep 2025

Low-intensity muscle contraction exercise reduces pain sensitivity by modulating peripheral pathology and spinal sensitization in end-stage knee osteoarthritis rats

in Non-Pharmacological Treatment of Pain

Satoko Motokawa
Junya Sakamoto
Ryo Sasaki
Yuki Nishi
Yuichiro Honda
Ayumi Takahashi
Minoru Okita

Frontiers in Pain Research

doi 10.3389/fpain.2025.1644177

248 views

Perspective

Published on 26 Sep 2025

Exploring pain and suffering through spatial acousmatic music: innovative perspectives beyond conventional music therapy

in Non-Pharmacological Treatment of Pain

Nikos Stavropoulos
Mark I. Johnson

Frontiers in Pain Research

doi 10.3389/fpain.2025.1672412

447 views

Brief Research Report

Published on 17 Sep 2025

Unstimulated inflammatory activity is associated with treatment response to cognitive-behavioral therapy for urologic chronic pelvic pain

in Non-Pharmacological Treatment of Pain

L. C. McKernan
L. J. Crofford
S. Bruehl
T. W. McGonigle
A. G. Kelly
A. M. Ryden
S. L. Sutherland
D. J. Clauw
D. A. Williams
R. R. Dmochowski

Frontiers in Pain Research

doi 10.3389/fpain.2025.1593807

526 views

Clinical Trial

Published on 18 Aug 2025

Novel multimodal mechanical stimulation is superior to TENS to treat and prevent chronic low back pain: a randomized controlled trial

in Non-Pharmacological Treatment of Pain

Amy Lynn Baxter
Jena L. Etnoyer-Slaski
Owen Tucker
Jessica Allia Rice Williams
Kevin Swartout
Lindsey L. Cohen
M. Louise Lawson

Frontiers in Pain Research

doi 10.3389/fpain.2025.1625420

1,739 views

Perspective

Published on 14 Aug 2025

An integral vision of pain and its persistence: a whole-person, whole-system, salutogenic perspective

in Non-Pharmacological Treatment of Pain

Mark I. Johnson

Frontiers in Pain Research

doi 10.3389/fpain.2025.1641571

1,094 views
1 citation

Review

Published on 12 Aug 2025

Efficacy of pulsed radiofrequency stimulation in patients with chronic pain: a narrative review

in Non-Pharmacological Treatment of Pain

Wei Lin
Lingling Lou
Dawei Chu
Yidong Lv
Liujun Tian
Bin Wang

Frontiers in Pain Research

doi 10.3389/fpain.2025.1544909

1,326 views

Original Research

Published on 24 Jul 2025

Whole-body cryostimulation exposures effectively alleviates menstrual-related pain and associated sleep disturbances in young women: a randomized controlled trial

in Non-Pharmacological Treatment of Pain

Quentin Bretonneau
Coralie Arc-Chagnaud
Benoit Dugué
Olivier Dupuy
Nathalie Delpech
Carina Enea
Laurent Bosquet

Frontiers in Pain Research

doi 10.3389/fpain.2025.1614153

975 views

Clinical Trial

Published on 10 Jul 2025

Preventing opioid prescribing for low back pain using multimodal mechanical stimulation vs. TENS: a randomized-controlled trial

in Non-Pharmacological Treatment of Pain

Amy L. Baxter
Jena L. Etnoyer-Slaski
Jessica Allia Rice Williams
Kevin Swartout
Lindsey L. Cohen
M. Louise Lawson

Frontiers in Pain Research

doi 10.3389/fpain.2025.1612572

3,048 views

Original Research

Published on 01 Jul 2025

Feasibility and user experience of augmented reality psychoeducation and mindfulness body scan for chronic low back pain

in Non-Pharmacological Treatment of Pain

Robin Conen
Nikolai Hepke
Jörg Lohscheller
Steffen Mueller
Ana N. Tibubos

Frontiers in Pain Research

doi 10.3389/fpain.2025.1600637

1,279 views

Hypothesis and Theory

Published on 26 Jun 2025

Additional evidence from a case report supports a novel hypothesis on the association between complex regional pain syndrome and lymphedema

in Non-Pharmacological Treatment of Pain

M. Mark Melin
John C. Rasmussen
Melissa B. Aldrich
Ron J. Karni
Caroline E. Fife
Kristen A. Eckert

Frontiers in Pain Research

doi 10.3389/fpain.2025.1540930

1,620 views

Original Research

Published on 11 Jun 2025

The meaning of manageable neuropathic pain after SCI

in Non-Pharmacological Treatment of Pain

Marlon L. Wong
Kimberly D. Anderson
Kathryn E. Roach
Linda Robayo
Nicholas P. Cherup
Roberta Vastano
Gabriel Fernandez
Eva Widerström-Noga

Frontiers in Pain Research

doi 10.3389/fpain.2025.1540395

1,351 views

Original Research

Published on 27 May 2025

Impact of a pain education program for people with spinal cord injury who experience neuropathic pain

in Non-Pharmacological Treatment of Pain

Nicholas P. Cherup
Kimberly D. Anderson
Marlon L. Wong
Gabriel E. Fernandez
Linda E. Robayo
Kathryn Roach
Roberta Vastano
Eva Widerstrom-Noga

Frontiers in Pain Research

doi 10.3389/fpain.2025.1569446

1,282 views

Review

Published on 09 May 2025

From didactic explanations to co-design, sequential art and embodied learning: challenges, criticisms and future directions of patient pain education

in Non-Pharmacological Treatment of Pain

G. Lorimer Moseley
Amelia Mardon
James Watson
Felicity Braithwaite
Monique V. Wilson
Trevor Barker
James Lawrence
Dianne Sheppard
Michiel F. Reneman
Jennifer Stinson

Frontiers in Pain Research

doi 10.3389/fpain.2025.1536112

6,582 views
2 citations

Original Research

Published on 28 Apr 2025

Long-term pain and health economic outcomes in adults receiving multidisciplinary CBT for chronic pain: the role of psychological inflexibility

in Non-Pharmacological Treatment of Pain

Sophia Åkerblom
Lance M. McCracken
Marcelo Rivano Fischer
Sean Perrin

Frontiers in Pain Research

doi 10.3389/fpain.2025.1547540

1,644 views
1 citation

Original Research

Published on 17 Apr 2025

The interplay between pulse width and activation depth in TENS: a computational study

in Non-Pharmacological Treatment of Pain

Alexander Guillen
Dennis Q. Truong
Yusuf O. Cakmak
Sheng Li
Abhishek Datta

Frontiers in Pain Research

doi 10.3389/fpain.2025.1526277

1,925 views
1 citation

Systematic Review

Published on 15 Apr 2025

Assessment of non-pharmacological nursing strategies for pain management in tumor patients: a systematic review and meta-analysis

in Non-Pharmacological Treatment of Pain

Shen Yan
Feng Yan
Pei Liangyu
Xu Fei

Frontiers in Pain Research

doi 10.3389/fpain.2025.1447075

7,670 views
1 citation