Frontiers in Pain Research | Pharmacological Treatment of Pain

Brief Research Report

Accepted on 08 Jul 2025

The effect of non-opioid multimodal analgesics and dexamethasone monotherapy on acute incisional pain behaviors in rats

in Pharmacological Treatment of Pain

Ratan K Banik
Twan Sia
Malcolm Johns
Donald Simone

Frontiers in Pain Research

doi 10.3389/fpain.2025.1569246

Brief Research Report

Published on 11 Jun 2025

Sleep hygiene linked to patient-reported outcomes & objective sleep measures prior to upper extremity orthopaedic surgery

in Pharmacological Treatment of Pain

Nicholas A. Giordano
Tatiana Getz
Michael Gottschalk
Andrew H. Miller
Kim Dupree Jones
Jasmine Park
Yining Zhu
Annabelle Gong
Jack Hudson
Selma Selimovic

Frontiers in Pain Research

doi 10.3389/fpain.2025.1589748

832 views

Editorial

Published on 10 Jun 2025

Editorial: Current treatment strategies and integrative medicine for management of pain in sickle cell disease

in Pharmacological Treatment of Pain

Kimberlei A. Richardson
Gabrielle Lynn McLemore
Keesha Powell-Roach
Kalpna Gupta

Frontiers in Pain Research

doi 10.3389/fpain.2025.1621147

777 views

Mini Review

Published on 04 Jun 2025

Widespread pain syndrome in long COVID-19: melatonin as an adjuvant treatment

in Pharmacological Treatment of Pain

Amine Souissi
Pablo Prieto-González
Helmi Ben Saad

Frontiers in Pain Research

doi 10.3389/fpain.2025.1609095

1,082 views

Original Research

Published on 21 Feb 2025

Unpacking excessive polypharmacy patterns among individuals living with chronic pain in Quebec: a longitudinal study

in Pharmacological Treatment of Pain

Gwenaelle De Clifford-Faugère
Hermine Lore Nguena Nguefack
Nancy Ménard
Sylvie Beaudoin
M. Gabrielle Pagé
Line Guénette
Catherine Hudon
Oumar Mallé Samb
Anaïs Lacasse

Frontiers in Pain Research

doi 10.3389/fpain.2025.1512878

1,331 views

Original Research

Published on 14 Feb 2025

Evaluation of long-term outcomes with intrathecal opioid treatment: a comparison utilizing data derived from pain clinic populations in Australia and New Zealand

in Pharmacological Treatment of Pain

Elouise Rose Comber
Jenny Strong
Orla Moore
Asaduzzaman Khan
James O’Callaghan
Benjamin Manion
Brendan Joseph Moore
Maree Therese Smith

Frontiers in Pain Research

doi 10.3389/fpain.2025.1527371

890 views

Review

Published on 31 Jan 2025

Phytochemical-based therapeutics from traditional eastern medicine: analgesic effects and ion channel modulation

in Pharmacological Treatment of Pain

Sung Eun Kim
Geehoon Chung
Sun Kwang Kim

Frontiers in Pain Research

doi 10.3389/fpain.2025.1537154

1,638 views
1 citation

Original Research

Published on 24 Jan 2025

Systemic antihyperalgesic effect of a novel conotoxin from Californiconus californicus in an inflammatory pain model

in Pharmacological Treatment of Pain

Joaquín López-Carrillo
Johanna Bernáldez-Sarabia
Tushar J. Pawar
Samanta Jiménez
Salvador Dueñas
Andrea Figueroa-Montiel
José L. Olivares-Romero
Vinicio Granados-Soto
Alexei F. Licea-Navarro
Nadia L. Caram-Salas

Frontiers in Pain Research

doi 10.3389/fpain.2024.1500789

1,626 views

Editorial

Published on 07 Jan 2025

Editorial: Preclinical animal models and measures of pain: improving predictive validity for analgesic drug development - volume II

in Pharmacological Treatment of Pain

Anke Tappe-Theodor
Thomas J. Martin
S. Stevens Negus

Frontiers in Pain Research

doi 10.3389/fpain.2024.1523938

1,101 views

Systematic Review

Published on 07 Jan 2025

Pregabalin vs. gabapentin in the treatment of neuropathic pain: a comprehensive systematic review and meta-analysis of effectiveness and safety

in Pharmacological Treatment of Pain

Víctor Mayoral
Rafael Galvez
Marta Ferrándiz
Xoán Miguéns Vázquez
Carlos Cordero-García
Antonio Alcántara Montero
Concepción Pérez
María Pérez-Páramo

Frontiers in Pain Research

doi 10.3389/fpain.2024.1513597

27,183 views
3 citations

Original Research

Published on 07 Jan 2025

Real-world evaluation of select adverse drug reactions and healthcare utilization associated with parenteral Ibuprofen and ketorolac in adult and pediatric patients

in Pharmacological Treatment of Pain

Mosadoluwa Afolabi
Jensy Rodriguez-Silva
Ishveen Chopra
Ines Macias-Perez
Jason Makii
Emily Durr
Theresa Human

Frontiers in Pain Research

doi 10.3389/fpain.2024.1484948

2,397 views

Perspective

Published on 10 Dec 2024

A perspective: neuraxial therapeutics in pain management: now and future

in Pharmacological Treatment of Pain

Jose DeAndres
Anthony H. Dickenson
Salim Hayek
Andreas Linninger
Tony L. Yaksh

Frontiers in Pain Research

doi 10.3389/fpain.2024.1505019

924 views

Clinical Trial

Published on 25 Nov 2024

Cannabis combined with oxycodone for pain relief in fibromyalgia pain: a randomized clinical self-titration trial with focus on adverse events

in Pharmacological Treatment of Pain

Cornelis Jan van Dam
Cornelis Kramers
Arnt Schellekens
Marcel Bouvy
Eveline van Dorp
Mikael A. Kowal
Erik Olofsen
Albert Dahan
Marieke Niesters
Monique van Velzen

Frontiers in Pain Research

doi 10.3389/fpain.2024.1497111

18,039 views
3 citations

Brief Research Report

Published on 22 Nov 2024

Arginine supplementation improves lactate dehydrogenase levels in steady-state sickle cell patients: preliminary findings from Kinshasa, the Democratic Republic of Congo

in Pharmacological Treatment of Pain

Ange C. M. Ngonde
Philippe N. Lukanu
Ange Mubiala
Michel N. Aloni

Frontiers in Pain Research

doi 10.3389/fpain.2024.1391666

1,170 views

Clinical Trial

Published on 14 Oct 2024

Enhancing analgesia in acute renal colic pain: a randomized controlled trial of gabapentin adjunct to ketorolac-based regimen

in Pharmacological Treatment of Pain

Parisa Kianpour
Parmis Valavioun
Pooya Payandemehr
Arash Safaei
Yasaman Borhani
Hooshyar Honarmand
Mojtaba Mojtahedzadeh
Kamal Basiri
Elahe karimpour-Razkenari
Farhad Najmeddin

Frontiers in Pain Research

doi 10.3389/fpain.2024.1427711

1,589 views
1 citation

Systematic Review

Published on 10 Oct 2024

Non-opioid psychiatric medications for chronic pain: systematic review and meta-analysis

in Pharmacological Treatment of Pain

Shahana Ayub
Anil Krishna Bachu
Lakshit Jain
Shanli Parnia
Siddhi Bhivandkar
Rizwan Ahmed
Jasleen Kaur
Surya Karlapati
Sakshi Prasad
Hansini Kochhar

Frontiers in Pain Research

doi 10.3389/fpain.2024.1398442

5,702 views