Frontiers in Pain Research

Original Research

Published on 13 Nov 2025

Prognostic value of activity patterns and stress measures for persistent pain and disability in acute neck pain: a 3-month follow-up study

Rita Morf
Cyrill Kernwein
Julia Jaeger
Leah Reicherzer
Jürgen Degenfellner
Sabina Hotz-Boendermaker

Frontiers in Pain Research

doi 10.3389/fpain.2025.1686389

994 views

Case Report

Published on 10 Nov 2025

Therapeutic observation of transcutaneous auricular vagus nerve stimulation for chronic migraine in pediatric patients: a case report

Siqi Weng
Yao Xue
Xuezhen Xiao
Berthold Hocher
Yishui Zhang
Xiaowei Yang
Qirui Liu
Yabin Ji

Frontiers in Pain Research

doi 10.3389/fpain.2025.1686043

1,405 views

Original Research

Published on 07 Nov 2025

Drug-induced headache reports: a comprehensive disproportionality and time-to-onset pharmacovigilance study using the FAERS database (2018–2024)

Abdulaziz Ibrahim Alzarea
Azfar Athar Ishaqui
Muhammad Bilal Maqsood
Abdullah Salah Alanazi
Aseel Awad Alsaidan
Tauqeer Hussain Mallhi
Narendar Kumar
Khalid M. Orayj
Sultan M. Alshahrani
Hassan H. Alhassan

Frontiers in Pain Research

doi 10.3389/fpain.2025.1670648

2,061 views

Brief Research Report

Published on 05 Nov 2025

Pain-attributed care task difficulty among dementia caregivers with chronic pain

Shelbie G. Turner
Aryn Lee
Karl A. Pillemer
M. Carrington Reid

Frontiers in Pain Research

doi 10.3389/fpain.2025.1661457

1,008 views
1 citation

Clinical Trial

Published on 03 Nov 2025

Effects of Tai Chi combined with intermediate frequency therapy on patients with chronic nonspecific neck pain: a randomized controlled trial

Kangni Deng
Yuheng Zhou
Jiasi Qian
Lilin Wang
Fan Yu
Bo Wang

Frontiers in Pain Research

doi 10.3389/fpain.2025.1700212

1,598 views

Case Report

Published on 31 Oct 2025

A 76-year-old male with abdominal cutaneous nerve entrapment syndrome: a case report

Karolina Kalanj
Matija Herceg
Antonio Ivanac
Sara Kalanj
Mirta Peček
Ana Brundula

Frontiers in Pain Research

doi 10.3389/fpain.2025.1588410

1,802 views

Review

Published on 30 Oct 2025

Integrating nociplastic pain into neuropathic pain framework: a proposal for a revised classification

Katsuhiro Toda

Frontiers in Pain Research

doi 10.3389/fpain.2025.1661667

3,025 views

Clinical Trial

Published on 29 Oct 2025

Astragalus membranaceus extract reduces functional knee joint pain: a randomized, double-blinded, placebo-controlled trial

Lorenzo Lippi
Alessio Turco
Girish H. Rudrappa
Stefano Moalli
Alessandro de Sire
Marco Invernizzi

Frontiers in Pain Research

doi 10.3389/fpain.2025.1595957

3,165 views

Review

Published on 28 Oct 2025

Pain mechanism and management strategy of rheumatoid arthritis

Dijun Wang
Ting Li
Weiqi Wang
Yonglan Ruan
Jiali Cai
Xiaojing Yan

Frontiers in Pain Research

doi 10.3389/fpain.2025.1693399

2,035 views
2 citations

Review

Published on 28 Oct 2025

Innate immunity in chemotherapy-induced peripheral neuropathy: recent advances

Nana Dong
Tongtong Lin

Frontiers in Pain Research

doi 10.3389/fpain.2025.1642306

1,482 views

Mini Review

Published on 27 Oct 2025

Exploring fascia in myofascial pain syndrome: an integrative model of mechanisms

Vlodeks Gromakovskis

Frontiers in Pain Research

doi 10.3389/fpain.2025.1712242

5,085 views
1 citation

Systematic Review

Published on 27 Oct 2025

Effectiveness of medical ozone injections into the intervertebral disc on relieving lumbosacral pain–a systematic review and meta-analysis

Donghui Cao
Xusheng Li
Xiao Zhang
Yanrong Tian
Wenbo Gu
Xi Zhu
Haifeng Yuan

Frontiers in Pain Research

doi 10.3389/fpain.2025.1668752

2,133 views

Review

Published on 20 Oct 2025

At the Intersection of Pain and Sleep: a Roadmap for Preclinical Pain Research

Clare M. Diester
William Joo

Frontiers in Pain Research

doi 10.3389/fpain.2025.1609524

1,997 views

Case Report

Published on 14 Oct 2025

Case Report: A case of toothache of cardiac origin with a long-term clinical course

Chizuko Maeda
Takayuki Suga
Kiyotoshi Oishi
Akira Toyofuku

Frontiers in Pain Research

doi 10.3389/fpain.2025.1625582

2,335 views

Original Research

Published on 13 Oct 2025

Acute postoperative pain trajectories and their impact on functional recovery following total knee arthroplasty

Caijin Wen
Qin Qin
Lu Wei
Xi Luo
Jing Zhang

Frontiers in Pain Research

doi 10.3389/fpain.2025.1659917

1,791 views

Original Research

Published on 13 Oct 2025

Metabolic resilience governs sex-specific pain recovery during hormonal aging: a multi-omics study of neuropathy in mice

Sara Marinelli
Claudia Rossi
Luisa Pieroni
Giacomo Giacovazzo
Valentina Vacca
Federica De Angelis
Ilaria Cicalini
Valentina Mastrorilli
Chiara Parisi
Zuleyha Nihan Yurtsever

Frontiers in Pain Research

doi 10.3389/fpain.2025.1655712

1,761 views

Review

Published on 07 Oct 2025

The burden of acute pain in the U.S. in the wake of the opioid crisis

James C. Hackworth
John E. Schneider
Maggie Do Valle
David Fam
Charles Argoff
Emanuela Offidani
Jim Potenziano

Frontiers in Pain Research

doi 10.3389/fpain.2025.1642035

3,264 views

Original Research

Published on 03 Oct 2025

Electroacupuncture therapy and bone cancer pain relief: experimental study on analgesic mechanisms in rats

Yanhua Li
Fangfei Li
Caizhi Xiao
Jie Cao
Dongqin Xia
Yongzhong Wu

Frontiers in Pain Research

doi 10.3389/fpain.2025.1597472

1,306 views

Original Research

Published on 01 Oct 2025

Migraine is associated with a higher risk of ischemic and hemorrhagic stroke: an analysis of the All of Us database

Nick Seah
Catherine D. Chong
Oana M. Dumitrascu
Todd J. Schwedt
Zhichao Cao
Teresa Wu

Frontiers in Pain Research

doi 10.3389/fpain.2025.1646142

2,007 views

Original Research

Published on 01 Oct 2025

Extreme pulse dosing of 10 kHz spinal cord stimulation: how low can you go?

Mayank Gupta
Amy Reinert
C. O. West
Rose Province-Azalde
Kerry Bradley

Frontiers in Pain Research

doi 10.3389/fpain.2025.1633424

1,716 views

Brief Research Report

Published on 29 Sep 2025

Primary somatosensory cortex oscillations in trigeminal neuralgia: laser-evoked signatures and their potential relevance to microvascular decompression

Britta N. Kretzschmar
André Rupp
Sandro M. Krieg
Rezvan Ahmadi

Frontiers in Pain Research

doi 10.3389/fpain.2025.1652354

1,501 views

Original Research

Published on 29 Sep 2025

Low-intensity muscle contraction exercise reduces pain sensitivity by modulating peripheral pathology and spinal sensitization in end-stage knee osteoarthritis rats

Satoko Motokawa
Junya Sakamoto
Ryo Sasaki
Yuki Nishi
Yuichiro Honda
Ayumi Takahashi
Minoru Okita

Frontiers in Pain Research

doi 10.3389/fpain.2025.1644177

2,014 views

Perspective

Published on 26 Sep 2025

Exploring pain and suffering through spatial acousmatic music: innovative perspectives beyond conventional music therapy

Nikos Stavropoulos
Mark I. Johnson

Frontiers in Pain Research

doi 10.3389/fpain.2025.1672412

1,631 views

Original Research

Published on 24 Sep 2025

Expectations about pain management after discharge from total hip and knee replacement surgery: a qualitative study with patients and prescribers

Ian Liang
Peter Youssef
Abby Haynes
Chung-Wei Christine Lin
Ian Harris
Mark Horsley
Caitlin M. P. Jones

Frontiers in Pain Research

doi 10.3389/fpain.2025.1647020

2,056 views

938 Publications

volumes

Volume 6 - 2025

Prognostic value of activity patterns and stress measures for persistent pain and disability in acute neck pain: a 3-month follow-up study

Therapeutic observation of transcutaneous auricular vagus nerve stimulation for chronic migraine in pediatric patients: a case report

Drug-induced headache reports: a comprehensive disproportionality and time-to-onset pharmacovigilance study using the FAERS database (2018–2024)

Pain-attributed care task difficulty among dementia caregivers with chronic pain

Effects of Tai Chi combined with intermediate frequency therapy on patients with chronic nonspecific neck pain: a randomized controlled trial

A 76-year-old male with abdominal cutaneous nerve entrapment syndrome: a case report

Integrating nociplastic pain into neuropathic pain framework: a proposal for a revised classification

Astragalus membranaceus extract reduces functional knee joint pain: a randomized, double-blinded, placebo-controlled trial

Pain mechanism and management strategy of rheumatoid arthritis

Innate immunity in chemotherapy-induced peripheral neuropathy: recent advances

Exploring fascia in myofascial pain syndrome: an integrative model of mechanisms

Effectiveness of medical ozone injections into the intervertebral disc on relieving lumbosacral pain–a systematic review and meta-analysis

At the Intersection of Pain and Sleep: a Roadmap for Preclinical Pain Research

Case Report: A case of toothache of cardiac origin with a long-term clinical course

Acute postoperative pain trajectories and their impact on functional recovery following total knee arthroplasty

Metabolic resilience governs sex-specific pain recovery during hormonal aging: a multi-omics study of neuropathy in mice

The burden of acute pain in the U.S. in the wake of the opioid crisis

Electroacupuncture therapy and bone cancer pain relief: experimental study on analgesic mechanisms in rats

Migraine is associated with a higher risk of ischemic and hemorrhagic stroke: an analysis of the All of Us database

Extreme pulse dosing of 10 kHz spinal cord stimulation: how low can you go?

Primary somatosensory cortex oscillations in trigeminal neuralgia: laser-evoked signatures and their potential relevance to microvascular decompression

Low-intensity muscle contraction exercise reduces pain sensitivity by modulating peripheral pathology and spinal sensitization in end-stage knee osteoarthritis rats

Exploring pain and suffering through spatial acousmatic music: innovative perspectives beyond conventional music therapy

Expectations about pain management after discharge from total hip and knee replacement surgery: a qualitative study with patients and prescribers