Frontiers in Parasitology | Parasite Diagnostics

Original Research

Published on 21 Nov 2025

Assessing the performance of TRX and DUF148 antigens for detection of prepatent Guinea worm (Dracunculus medinensis) infection in dogs

in Parasite Diagnostics

Hassan Hakimi
Pabasara Weerarathne
Meriam N. Saleh
Raquel R. Rech
Richard Ngandolo Bongo Nare
Philip Ouakou Tchindebet
Sidouin K. Metinou
Jessica M. van Loben Sels
Lucienne Tritten
Guilherme G. Verocai

Frontiers in Parasitology

doi 10.3389/fpara.2025.1699367

643 views

Brief Research Report

Published on 06 Nov 2025

Assessing the diagnostic value of qPCR for Trichuris trichiura: sub-analysis of a multi-country clinical trial to determine the efficacy of albendazole compared to an albendazole-ivermectin fixed dose combination

in Parasite Diagnostics

Pedro E. Fleitas
Michel Bengtson
Augusto Messa
Brian Bartilol
Woyneshet Gelaye
Stella Kepha
Javier Gandasegui
Áuria de Jesus
Valdemiro Novela
Inácio Mandomando

Frontiers in Parasitology

doi 10.3389/fpara.2025.1679294

1,496 views

Case Report

Published on 06 Oct 2025

Multisystem involvement in hydatid disease: a case report of disseminated echinococcosis

in Parasite Diagnostics

Hanamanthraya Mallannagouda
Shivanand Melkundi
Sanjana Devarmani
Vedashree V. Tiwari

Frontiers in Parasitology

doi 10.3389/fpara.2025.1630827

1,063 views

Original Research

Published on 13 Aug 2025

Molecular diagnosis of Chagas disease in patients with megaesophagus exhibiting negative or inconclusive serological results

in Parasite Diagnostics

Angelica Martins Batista
Tycha Bianca Sabaini Pavan
Eros Antonio de Almeida
Daniel Maximo Corrêa de Alcantara
Paula Durante Andrade
Luiz Cláudio Martins
Jamiro da Silva Wanderley
Sandra Cecília Botelho Costa
Gláucia Elisete Barbosa Marcon

Frontiers in Parasitology

doi 10.3389/fpara.2025.1622149

1,196 views

General Commentary

Published on 22 Jul 2025

Commentary: Evaluation of the AiDx Assist device for automated detection of Schistosoma eggs in stool and urine samples in Nigeria

in Parasite Diagnostics

Nathkapach Kaewpitoon Rattanapitoon
Schawanya Kaewpitoon Rattanapitoon

Frontiers in Parasitology

doi 10.3389/fpara.2025.1633767

933 views

Original Research

Published on 29 May 2025

RDT performance through high-throughput bead-based antigen detection during malaria school survey in Senegal

in Parasite Diagnostics

Mamadou Alpha Diallo
Ibrahima M. Ndiaye
Djiby Sow
Mame Cheikh Seck
Khadim Diongue
Mariama Touré
Katerine E. Battle
Bassirou Ngom
Mouhamad Sy
Amy Gaye

Frontiers in Parasitology

doi 10.3389/fpara.2025.1598280

2,134 views

Original Research

Published on 17 Mar 2025

Evaluation of the AiDx Assist device for automated detection of Schistosoma eggs in stool and urine samples in Nigeria

in Parasite Diagnostics

Brice Meulah
Pytsje T. Hoekstra
Samuel Popoola
Satyajith Jujjavarapu
Moses Aderogba
Joseph O. Fadare
John A. Omotayo
David Bell
Cornelis H. Hokke
Lisette van Lieshout

Frontiers in Parasitology

doi 10.3389/fpara.2025.1440299

2,682 views
3 citations

Original Research

Published on 11 Mar 2025

Identification and characterization of the elusive protein backbone of the immuno-dominant and species-specific Em2(G11) metacestode antigen of Echinococcus multilocularis

in Parasite Diagnostics

Philipp A. Kronenberg
Teivi Laurimäe
Michael Reinehr
Ansgar Deibel
Sina Hasler
Peter Gehrig
Achim Weber
Peter Deplazes
Ramon M. Eichenberger

Frontiers in Parasitology

doi 10.3389/fpara.2025.1540215

1,969 views

Original Research

Published on 05 Mar 2025

TvLEGU-1 and TvLEGU-2 biomarkers for trichomoniasis are legumain-like cysteine peptidases secreted in vitro in a time-dependent manner

in Parasite Diagnostics

Esly Alejandra Euceda-Padilla
Miriam Guadalupe Mateo-Cruz
Jaime Ortega-López
Rossana Arroyo

Frontiers in Parasitology

doi 10.3389/fpara.2025.1546468

1,917 views

Case Report

Published on 10 Jan 2025

Unusual cholesterol crystal formation in a rare clinical case report of splenic echinococcal cyst in a patient from Sardinia, Italy

in Parasite Diagnostics

Cinzia Santucciu
Ashkan Hajjafari
Soheil Sadr
Scilla Mastrandrea
Carlo Rettaroli
Luca Simbula
Mariano Scaglione
Salvatore Masala
Angela Peruzzu
Giovanna Masala

Frontiers in Parasitology

doi 10.3389/fpara.2024.1498099

2,091 views

Original Research

Published on 04 Oct 2024

Detecting two Schistosoma circulating antigens – CCA and CAA – in urine and serum to improve diagnosis of human schistosomiasis

in Parasite Diagnostics

Pytsje T. Hoekstra
Claudia J. de Dood
Theresia Abdoel
Stan Hilt
Angela van Diepen
Katja Polman
Peter Kremsner
Lisette van Lieshout
Andrea Kreidenweiss
Ayola Akim Adegnika

Frontiers in Parasitology

doi 10.3389/fpara.2024.1460331

5,289 views
3 citations

Review

Published on 27 Aug 2024

Evolution of dirofilariasis diagnostic techniques from traditional morphological analysis to molecular-based techniques: a comprehensive review

in Parasite Diagnostics

A.M.M.T.B. Aththanayaka
B.S.W.M.T.B. Dayananda
H.A.K. Ranasinghe
L.D. Amarasinghe

Frontiers in Parasitology

doi 10.3389/fpara.2024.1427449

6,196 views
6 citations

Mini Review

Published on 01 Jul 2024

From laboratory to clinical practice: an update of the immunological and molecular tools for neurocysticercosis diagnosis

in Parasite Diagnostics

Luz M. Toribio
Javier A. Bustos
Hector H. Garcia

Frontiers in Parasitology

doi 10.3389/fpara.2024.1394089

4,749 views
5 citations

Systematic Review

Published on 27 Jun 2024

Nuttalliella namaqua Bedford, 1931, a sole extant species of the genus Nuttalliella – a scoping review

in Parasite Diagnostics

Maphuti Betty Ledwaba
Dikeledi Petunia Malatji

Frontiers in Parasitology

doi 10.3389/fpara.2024.1401351

3,380 views
1 citation

Original Research

Published on 13 May 2024

Next step towards point-of-care molecular diagnosis of female genital schistosomiasis (FGS): evaluation of an instrument-free LAMP procedure

in Parasite Diagnostics

Kim J. M. van Bergen
Eric A.T. Brienen
Bodo S. Randrianasolo
Charles E. Ramarokoto
Peter Leutscher
Eyrun F. Kjetland
Angela van Diepen
Floris Dekker
Vittorio Saggiomo
Aldrik H. Velders

Frontiers in Parasitology

doi 10.3389/fpara.2024.1297310

4,049 views
4 citations

Brief Research Report

Published on 26 Mar 2024

Toward the elimination of NTDs: application of cost-effective and sensitive molecular environmental surveillance tools—a pilot study

in Parasite Diagnostics

Juliet Hodgson
Gideon Twieku
Gerard Quarcoo
Emmanuel Armah
Mike Yaw Osei-Atweneboana
Samuel Armoo

Frontiers in Parasitology

doi 10.3389/fpara.2024.1340161

2,017 views

Original Research

Published on 14 Mar 2024

Development of a rapid and highly sensitive nucleic acid-based diagnostic test for schistosomes, leveraging on identical multi-repeat sequences

in Parasite Diagnostics

Ombeni Ally
Bernard N. Kanoi
Shwetha Kamath
Clement Shiluli
Eric M. Ndombi
Maurice Odiere
Gerald Misinzo
Steven Ger Nyanjom
Chunduri Kiran Kumar
Lucy Ochola

Frontiers in Parasitology

doi 10.3389/fpara.2024.1361493

3,979 views
2 citations

Perspective

Published on 13 Feb 2024

Usefulness of polymerase chain reaction tests in Chagas disease studies

in Parasite Diagnostics

Norma Bautista-Lopez
Momar Ndao

Frontiers in Parasitology

doi 10.3389/fpara.2024.1292143

4,170 views
2 citations

Original Research

Published on 27 Nov 2023

Limited value of current and new in silico predicted oocyst-specific proteins of Toxoplasma gondii for source-attributing serology

in Parasite Diagnostics

Nadia-María López-Ureña
Rafael Calero-Bernal
Bretislav Koudela
Simona Cherchi
Alessia Possenti
Fabio Tosini
Sandra Klein
Carmen San Juan-Casero
Silvia Jara-Herrera
Pikka Jokelainen

Frontiers in Parasitology

doi 10.3389/fpara.2023.1292322

2,372 views
3 citations

Perspective

Published on 21 Nov 2023

Clinical use of molecular methods for Trypanosoma cruzi infection in endemic and non-endemic countries: Benefits, limitations and challenges

in Parasite Diagnostics

Maria-Jesus Pinazo
Colin J. Forsyth
Constanza Lopez-Albizu
Margarita María Catalina Bisio
Adriana González-Martínez
Laura Bohorquez
Jimy Pinto
Israel Molina
Andrea Marchiol
Rafael Herazo

Frontiers in Parasitology

doi 10.3389/fpara.2023.1241154

3,666 views
6 citations

Original Research

Published on 17 Nov 2023

Longitudinal study of cross-reactive antigenemia in individuals with high Loa loa microfilarial density reveals promising biomarkers for distinguishing lymphatic filariasis from loiasis

in Parasite Diagnostics

Linda Djune-Yemeli
Marla Hertz
Hugues C. Nana-Djeunga
Amy Rush
Petra Erdmann-Gilmore
Robert Sprung
Jean Gabin Bopda
Reid Townsend
Palmer Masumbe Netongo
Joseph Kamgno

Frontiers in Parasitology

doi 10.3389/fpara.2023.1292837

2,362 views
3 citations

Original Research

Published on 27 Oct 2023

Real-time PCR for diagnosing and monitoring treatment effect of Strongyloides stercoralis infection in a non-endemic setting

in Parasite Diagnostics

Linda J. Wammes
Suzanne A. V. van Asten
Lisette van Lieshout
Els Wessels
Jaco J. Verweij

Frontiers in Parasitology

doi 10.3389/fpara.2023.1277372

3,950 views
4 citations

Original Research

Published on 23 Oct 2023

Identification of biomarker candidates for filarial parasite infections by analysis of extracellular vesicles

in Parasite Diagnostics

Devyn Yates
Lucia S. Di Maggio
Bruce A. Rosa
Robert W. Sprung
Petra Erdmann-Gilmore
R. Reid Townsend
Philip J. Budge
Joseph Kamgno
Makedonka Mitreva
Gary J. Weil

Frontiers in Parasitology

doi 10.3389/fpara.2023.1281092

2,615 views
5 citations

Perspective

Published on 09 Oct 2023

An end is in sight: a perspective on PCR as an endpoint for Chagas disease treatment trials

in Parasite Diagnostics

Natasha S. Hochberg
Srinivasa P. S. Rao
Gerhild Angyalosi
Xiaojun Zhao
Leticia Carballo
Caroline Demacq
Sofia Braud-Perez
Daniela Wieser
JP Casas
John Millholland

Frontiers in Parasitology

doi 10.3389/fpara.2023.1272386

2,042 views
2 citations

34 articles

articles

Assessing the performance of TRX and DUF148 antigens for detection of prepatent Guinea worm (Dracunculus medinensis) infection in dogs

Assessing the diagnostic value of qPCR for Trichuris trichiura: sub-analysis of a multi-country clinical trial to determine the efficacy of albendazole compared to an albendazole-ivermectin fixed dose combination

Multisystem involvement in hydatid disease: a case report of disseminated echinococcosis

Molecular diagnosis of Chagas disease in patients with megaesophagus exhibiting negative or inconclusive serological results

Commentary: Evaluation of the AiDx Assist device for automated detection of Schistosoma eggs in stool and urine samples in Nigeria

RDT performance through high-throughput bead-based antigen detection during malaria school survey in Senegal

Evaluation of the AiDx Assist device for automated detection of Schistosoma eggs in stool and urine samples in Nigeria

Identification and characterization of the elusive protein backbone of the immuno-dominant and species-specific Em2(G11) metacestode antigen of Echinococcus multilocularis

TvLEGU-1 and TvLEGU-2 biomarkers for trichomoniasis are legumain-like cysteine peptidases secreted in vitro in a time-dependent manner

Unusual cholesterol crystal formation in a rare clinical case report of splenic echinococcal cyst in a patient from Sardinia, Italy

Detecting two Schistosoma circulating antigens – CCA and CAA – in urine and serum to improve diagnosis of human schistosomiasis

Evolution of dirofilariasis diagnostic techniques from traditional morphological analysis to molecular-based techniques: a comprehensive review

From laboratory to clinical practice: an update of the immunological and molecular tools for neurocysticercosis diagnosis

Nuttalliella namaqua Bedford, 1931, a sole extant species of the genus Nuttalliella – a scoping review

Next step towards point-of-care molecular diagnosis of female genital schistosomiasis (FGS): evaluation of an instrument-free LAMP procedure

Toward the elimination of NTDs: application of cost-effective and sensitive molecular environmental surveillance tools—a pilot study

Development of a rapid and highly sensitive nucleic acid-based diagnostic test for schistosomes, leveraging on identical multi-repeat sequences

Usefulness of polymerase chain reaction tests in Chagas disease studies

Limited value of current and new in silico predicted oocyst-specific proteins of Toxoplasma gondii for source-attributing serology

Clinical use of molecular methods for Trypanosoma cruzi infection in endemic and non-endemic countries: Benefits, limitations and challenges

Longitudinal study of cross-reactive antigenemia in individuals with high Loa loa microfilarial density reveals promising biomarkers for distinguishing lymphatic filariasis from loiasis

Real-time PCR for diagnosing and monitoring treatment effect of Strongyloides stercoralis infection in a non-endemic setting

Identification of biomarker candidates for filarial parasite infections by analysis of extracellular vesicles

An end is in sight: a perspective on PCR as an endpoint for Chagas disease treatment trials