Frontiers in Pediatrics | Pediatric Hematology and Hematological Malignancies

Brief Research Report

Published on 11 Aug 2025

The expression pattern and role of circulating CXCR5+γδ T cells in children with newly diagnosed immune thrombocytopenia

in Pediatric Hematology and Hematological Malignancies

Jian-Yong Wang
Yi Xin
Xiao-Li Wang
Lin-Lin Li
Ai-Min Li
Xiao-Lu Zhang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1646877

1,516 views

Case Report

Published on 11 Aug 2025

Case Report: Eltrombopag in mosaic and gene therapy-treated patients with Fanconi anemia

in Pediatric Hematology and Hematological Malignancies

Josune Zubicaray
June Iriondo
Elena Sebastián
Alejandro Sanz
Paula Rio
Jean Soulier
Sonsoles San Román
José J. Uriz
Susana Navarro
Eileen Nicoletti

Frontiers in Pediatrics

doi 10.3389/fped.2025.1625751

1,923 views

Original Research

Published on 29 Jul 2025

Study on the diagnostic and differential value of thalassemia through combined blood routine examination and reticulocyte detection

in Pediatric Hematology and Hematological Malignancies

Haiyan Ke
Hongxia Zhang
Hong Jiang
Sheng Li
Hui Wang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1616766

3,009 views

Original Research

Published on 24 Jul 2025

Prognostic value of blood inflammatory composite markers in the survival of pediatric patients with secondary hemophagocytic lymphohistiocytosis

in Pediatric Hematology and Hematological Malignancies

Nandu Luo
Xin Xie
Yan Chen
Zuochen Du
Pei Huang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1458490

1,305 views

Case Report

Published on 18 Jul 2025

Progressive cephalohematoma in a neonate revealing severe hemophilia a owing to intron 22 inversion: a case report

in Pediatric Hematology and Hematological Malignancies

Cheng Peng
Qiuyue Kou
Qianqian Xia
Zhongfen Cao
Lili Liu
Xinlin Hou
Zezhong Tang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1649183

2,257 views

Original Research

Published on 17 Jul 2025

Analysis of risk factors for Epstein–Barr virus reactivation and progression to post-transplant lymphoproliferative disorder in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation

in Pediatric Hematology and Hematological Malignancies

Lanzhou Jia
Hui Yang
Ya Zhou
Yan Meng
Luying Zhang
Xiaoying Lei
Xianming Guan
Jie Yu
Ying Dou

Frontiers in Pediatrics

doi 10.3389/fped.2025.1627990

2,615 views
1 citation

Original Research

Published on 10 Jul 2025

The effect of prophylactic FVIII infusion combined with personalized rehabilitation on joint health and quality of life in children with hemophilia

in Pediatric Hematology and Hematological Malignancies

Yaojin Sun
Qian Zhang
Xiaojie Gu
Yongjun Fang
Jie Huang
Heng Zhang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1578617

2,060 views

Correction

Published on 02 Jul 2025

Correction: Third generation sequencing transforms the way of the screening and diagnosis of thalassemia: a mini-review

in Pediatric Hematology and Hematological Malignancies

Lixia Zhan
Chunrong Gui
Wei Wei
Juliang Liu
Baoheng Gui

Frontiers in Pediatrics

doi 10.3389/fped.2025.1637415

948 views

Original Research

Published on 05 Jun 2025

Differentiating primary bone marrow failure syndromes in children: a retrospective analysis of early clinical and laboratory features

in Pediatric Hematology and Hematological Malignancies

Yan-Li Leng
Yu-Qi Zhao
Hong-Juan Li
Yan Gu
Yan Han
GuYu Ding
Xiaoyue Zhang
Xu Li
Hui-Di Feng
ZiYun Lin

Frontiers in Pediatrics

doi 10.3389/fped.2025.1557212

2,486 views

Case Report

Published on 26 May 2025

Case Report: Clinical management of a severe DBA patient with a novel RPS19 mutation

in Pediatric Hematology and Hematological Malignancies

Junfen Zhou
Jiayi Zhong
Yisha Zhao
Miaojun Mo
Xianbo Chen
Huangjia Zhou
Luya Zhang
Li Lin
Yichi Zhang
Xiaohong Tao

Frontiers in Pediatrics

doi 10.3389/fped.2025.1590183

2,235 views

Editorial

Published on 29 Apr 2025

Editorial: Pediatric myeloid neoplasms: new insights into diagnosis, prognosis, and treatment

in Pediatric Hematology and Hematological Malignancies

Viviane Lamim Lovatel
Jeffrey J. Pu
Teresa de Souza Fernandez

Frontiers in Pediatrics

doi 10.3389/fped.2025.1604478

1,441 views

Case Report

Published on 28 Apr 2025

Case Report: Severe hemophilia B patient with inhibitor and anaphylaxis reaction to FIX, successfully managed with concizumab prophylaxis therapy

in Pediatric Hematology and Hematological Malignancies

Elisa Bonetti
Maria Pia Esposto
Ada Zaccaron
Chiara Guardo
Giulia Caddeo
Matteo Chinello
Rita Balter
Vincenza Pezzella
Virginia Vitale
Simone Cesaro

Frontiers in Pediatrics

doi 10.3389/fped.2025.1576821

3,104 views
1 citation

Case Report

Published on 28 Apr 2025

Case Report: Post-splenectomy bulky pelvic splenosis in an adolescent with hereditary spherocytosis

in Pediatric Hematology and Hematological Malignancies

Benedetta Elena Di Majo
Nicolò Peccatori
Alessandra Inzoli
Luca Degrate
Marta Jaconi
Michele Ratti
Alessandra Casiraghi
Giulia Maria Ferrari
Debora Sala
Andrea Biondi

Frontiers in Pediatrics

doi 10.3389/fped.2025.1581533

1,734 views

Case Report

Published on 14 Apr 2025

Rhino-orbito-cerebral mucormycosis after allogeneic hematopoietic stem cell transplantation for very severe aplastic anemia in a child: a case report

in Pediatric Hematology and Hematological Malignancies

Yimei Ma
Ziting Xia
Bochao Cheng
Bo Wang
Xingming Huang
Xiaoxi Lu

Frontiers in Pediatrics

doi 10.3389/fped.2025.1529656

3,014 views
1 citation

Case Report

Published on 10 Apr 2025

Identification of a novel mutation in the CLCN7 gene in pediatric osteopetrosis: case report

in Pediatric Hematology and Hematological Malignancies

Aoshuang Jiang
Tianping Chen
Nan Wei
Chenglin Zhu
Jie Wang
Hongjun Liu
Min Wang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1549961

1,854 views
1 citation

Original Research

Published on 03 Apr 2025

Risk factors for hemorrhagic cystitis in children with severe beta-thalassemia after allogeneic hematopoietic stem cell transplantation

in Pediatric Hematology and Hematological Malignancies

Hui-Hong Dou
Jian-Ming Luo
Yan-Jun Zhao
Ji-Gan Wang
Yuan-Han Qin

Frontiers in Pediatrics

doi 10.3389/fped.2025.1558099

1,690 views
1 citation

Original Research

Published on 21 Mar 2025

Caregiver and provider perspectives on developmental services for children with sickle cell disease: a mixed methods analysis

in Pediatric Hematology and Hematological Malignancies

Mollie Tamboli
Erin MacArthur
Natalie Collins
Eunyoung Kang
Maria Fernandez
Jerlym S. Porter
Heather M. Conklin
Allison A. King
Jane S. Hankins
Andrew M. Heitzer

Frontiers in Pediatrics

doi 10.3389/fped.2025.1530457

2,939 views
1 citation

Original Research

Published on 21 Mar 2025

Relationship between patent ductus arteriosus and platelet indices in newborn: a systematic review and meta-analysis

in Pediatric Hematology and Hematological Malignancies

Yanbing An
Gaowa Arigong
Wuyun Zhao
Rina Su
Xiaoyun Wang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1455183

1,662 views

Original Research

Published on 20 Mar 2025

Clinical outcomes and relapse patterns in pediatric acute leukemia patients undergoing hematopoietic cell transplantation: a multicenter Brazilian experience

in Pediatric Hematology and Hematological Malignancies

Polliany Roberta Dorini Pelegrina
Rita de Cassia Barbosa Tavares
Adriana Mello Rodrigues
Gisele Loth
Samantha Nichele
Cilmara Kuwahara
Fernanda Moreira de Lara Benini
Carolina Martins de Almeida Peixoto
Juliana Bach
Joanna Trennepohl

Frontiers in Pediatrics

doi 10.3389/fped.2025.1573334

2,540 views
1 citation

Review

Published on 14 Mar 2025

Microbiota modulation for infectious complications following allogeneic hematopoietic stem cell transplantation in pediatric hematological malignancies

in Pediatric Hematology and Hematological Malignancies

Wei Dai
Xiaofan Chen
Huanhuan Zhou
Ning Liu
Mengdi Jin
Zhi Guo

Frontiers in Pediatrics

doi 10.3389/fped.2025.1509612

2,008 views
2 citations

Original Research

Published on 14 Feb 2025

Similarities and differences in the clinical features and management of primary lymphedema and kaposiform hemangioendothelioma associated with lymphedema in children

in Pediatric Hematology and Hematological Malignancies

Yujia Zhang
Tong Qiu
Congxia Yang
Jiangyuan Zhou
Min Yang
Xue Gong
Zixin Zhang
Yuru Lan
Xuepeng Zhang
Siyuan Chen

Frontiers in Pediatrics

doi 10.3389/fped.2025.1480213

1,615 views
1 citation

Brief Research Report

Published on 10 Feb 2025

Clinical characteristics of hereditary spherocytosis with red blood cell membrane protein gene variants

in Pediatric Hematology and Hematological Malignancies

Jingying Cheng
Liqiang Zhang
Jiafeng Yao
Shasha Zhao
Jin Jiang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1523288

2,648 views
1 citation

Original Research

Published on 28 Jan 2025

Secondary neoplasms in survivors of pediatric acute lymphoblastic leukemia and lymphoblastic lymphoma: a single-center, retrospective study

in Pediatric Hematology and Hematological Malignancies

Eri Ushida
Hidemi Toyoda
Atsushi Kohso
Yosuke Okumura
Kaori Niwa
Takahiro Ito
Mari Morimoto
Ryo Hanaki
Keishiro Amano
Shotaro Iwamoto

Frontiers in Pediatrics

doi 10.3389/fped.2025.1530832

2,222 views
1 citation

Systematic Review

Published on 27 Jan 2025

Cardiac injury caused by iron overload in thalassemia

in Pediatric Hematology and Hematological Malignancies

Chunxi Fu
Xue Yang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1514722

4,037 views
4 citations

291 articles

articles

The expression pattern and role of circulating CXCR5+γδ T cells in children with newly diagnosed immune thrombocytopenia

Case Report: Eltrombopag in mosaic and gene therapy-treated patients with Fanconi anemia

Study on the diagnostic and differential value of thalassemia through combined blood routine examination and reticulocyte detection

Prognostic value of blood inflammatory composite markers in the survival of pediatric patients with secondary hemophagocytic lymphohistiocytosis

Progressive cephalohematoma in a neonate revealing severe hemophilia a owing to intron 22 inversion: a case report

Analysis of risk factors for Epstein–Barr virus reactivation and progression to post-transplant lymphoproliferative disorder in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation

The effect of prophylactic FVIII infusion combined with personalized rehabilitation on joint health and quality of life in children with hemophilia

Correction: Third generation sequencing transforms the way of the screening and diagnosis of thalassemia: a mini-review

Differentiating primary bone marrow failure syndromes in children: a retrospective analysis of early clinical and laboratory features

Case Report: Clinical management of a severe DBA patient with a novel RPS19 mutation

Editorial: Pediatric myeloid neoplasms: new insights into diagnosis, prognosis, and treatment

Case Report: Severe hemophilia B patient with inhibitor and anaphylaxis reaction to FIX, successfully managed with concizumab prophylaxis therapy

Case Report: Post-splenectomy bulky pelvic splenosis in an adolescent with hereditary spherocytosis

Rhino-orbito-cerebral mucormycosis after allogeneic hematopoietic stem cell transplantation for very severe aplastic anemia in a child: a case report

Identification of a novel mutation in the CLCN7 gene in pediatric osteopetrosis: case report

Risk factors for hemorrhagic cystitis in children with severe beta-thalassemia after allogeneic hematopoietic stem cell transplantation

Caregiver and provider perspectives on developmental services for children with sickle cell disease: a mixed methods analysis

Relationship between patent ductus arteriosus and platelet indices in newborn: a systematic review and meta-analysis

Clinical outcomes and relapse patterns in pediatric acute leukemia patients undergoing hematopoietic cell transplantation: a multicenter Brazilian experience

Microbiota modulation for infectious complications following allogeneic hematopoietic stem cell transplantation in pediatric hematological malignancies

Similarities and differences in the clinical features and management of primary lymphedema and kaposiform hemangioendothelioma associated with lymphedema in children

Clinical characteristics of hereditary spherocytosis with red blood cell membrane protein gene variants

Secondary neoplasms in survivors of pediatric acute lymphoblastic leukemia and lymphoblastic lymphoma: a single-center, retrospective study

Cardiac injury caused by iron overload in thalassemia