Frontiers in Pharmacology

Systematic Review

Accepted on 28 Jan 2026

Network Meta-Analysis of Pharmacological Treatments for Idiopathic Pulmonary Fibrosis: Evaluating Effects on Lung Function

in Experimental Pharmacology and Drug Discovery

Yajie Yin
Xinhui Wu
Zhihao Liu
Yinru Luo
Mi Jing
Kefeng Jing
Qiuyuan Li
Fei Wang
Ju Huang

Frontiers in Pharmacology

139 views

Review

Accepted on 28 Jan 2026

Magnesium Sulfate Pharmacology for Maternal and Critical-Care Indications: Mechanisms, Pharmacokinetics, and the Therapeutic Window

in Obstetric and Pediatric Pharmacology

Mingya Xia
Qiang Ni
Sha Zhu

Frontiers in Pharmacology

168 views

Original Research

Accepted on 28 Jan 2026

Profibrotic predictive toxicology in the lung

in Predictive Toxicology

Pooja Singh
Rajesh Sinha
Veena B Antony

Frontiers in Pharmacology

Original Research

Accepted on 28 Jan 2026

Eubacterium sp. mediates the anti-Obesity effect of Lotus leaf extract via Brown Adipose Tissue activation and White Fat Browning

in Ethnopharmacology

Shuhan Zou
Xianmei Yuan
Zhihui Wang
Shang-Gao Liao

Frontiers in Pharmacology

136 views

Systematic Review

Accepted on 28 Jan 2026

Danshen (Salvia miltiorrhiza) extract in Spinal Cord Injury (SCI): A Systematic Review and Meta-Analysis

in Ethnopharmacology

Dongping Wan
Rui Tang
Rui Wang
Haodong Wu
Feilong Li
Xiang Ji
Xi Gao
ShiHang Cao

Frontiers in Pharmacology

Review

Accepted on 28 Jan 2026

The Impact of Nutritional, Environmental, and Lifestyle Factors on Neurological Disorders: Therapeutic Implications and Mechanistic Insights

in Neuropharmacology

Dib Chakif
Julien Furrer

Frontiers in Pharmacology

129 views

Original Research

Accepted on 28 Jan 2026

Different treatments for Crohn's disease complicated with severe acute lower Gastrointestinal bleeding: Infliximab therapy is critical and cannot be ignored

in Gastrointestinal and Hepatic Pharmacology

Shuoyi Yao
Zheyu Wang
Mingyan Xie
Shengnan Wu
Yingjuan Feng
Xiaoming Liu
Fen Wang

Frontiers in Pharmacology

Review

Published on 28 Jan 2026

Wedelolactone, a natural coumestan with multiple pharmacological effects

in Experimental Pharmacology and Drug Discovery

Shanshan Han
Minghe Li
Longfei Yang
Xinming Zhuang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1670032

530 views

Original Research

Published on 28 Jan 2026

Therapeutic effects of Lactobacillus rhamnosus, thymol and their combination against neurotoxicity in propionic acid (PA)-induced autistic rats: insights into the role of the Nrf2/HO-1, Wnt3/β-catenin/GSK3β BDNF/p-TrkB/CREB, pI3K/Akt/mTOR, AMPK/SIRT-1, and PERK/CHOP/Bcl-2 pathways

in Neuropharmacology

Hoda A. Salem
Nermin I. Rizk
Moustafa H. AbdelSalam
Rehab Ahmed
Hebatallah Husseini Atteia
Ahmed M. E. Hamdan
Areej A. Alghamdi
Manar A. Alghusn
Renad A. Alatawi
Rawan A. Atallah

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1728908

899 views

Editorial

Published on 28 Jan 2026

Editorial: Food derived bioactive metabolites: unlocking their potential health benefits and medical potential

in Ethnopharmacology

Ruyu Yao
Massimo Lucarini
Alessandra Durazzo

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1772586

400 views

Original Research

Published on 28 Jan 2026

Real-world data on the abuse potential of medications for the treatment of insomnia: a disproportionality analysis of the FAERS database

in Experimental Pharmacology and Drug Discovery

Paul Saskin
William V. McCall
David N. Neubauer
Antonio Crucitti
Bradford Perry
Pierre Philippe Luyet
Riphed Jaziri
Cedric Vaillant

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1735180

1,116 views

Original Research

Published on 28 Jan 2026

Troxerutin, a herbal metabolite with antidiabetic and antihypercholesterolemic potential, regulates metabolic gene activity in male diabetic rats

in Ethnopharmacology

Saira Gul
Mahrukh Naseem
Irfan Shahzad Sheikh
Hafiz Muhammad Ali
Imtiaz Rabbani
Tariq Jamil
Sehar Gul
Zaid Chachar
Sana Ullah
Saima Asif

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1687575

946 views

Original Research

Published on 28 Jan 2026

NAPQI adducts in patients with selective hypersensitivity to acetaminophen

in Pharmacogenetics and Pharmacogenomics

Javier Gomez-Tabales
Jesus M. García-Menaya
Natalia Blanca-Lopez
María de las Olas Cerezo-Arias
Antonio Silva-Rodríguez
Pedro Ayuso
Elena García-Martín
José A. G. Agúndez

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1726508

1,026 views

Review

Published on 28 Jan 2026

Recent advances in mitochondria-targeted porphyrin-based metal-organic frameworks for enhanced cancer therapy

in Translational Pharmacology

Jiawen Tao
Zhifei Yuan
Mengjiao Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1764901

603 views

Systematic Review

Published on 28 Jan 2026

Efficacy and safety of midazolam versus dexmedetomidine in mechanically ventilated intensive care unit patients: a systematic review and meta-analysis

in Neuropharmacology

Wei Peng
Yuan-Yuan Lin
An-Ni Lin
Yong-Jia Zheng
Xu-Liang Cai
Yue-Fei Li
Qian-Yi Tang
Huan He

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1733161

602 views

Systematic Review

Published on 28 Jan 2026

Targeted therapies in pediatric B-Cell acute lymphoblastic leukemia: mechanisms, efficacy, and future directions

in Pharmacology of Anti-Cancer Drugs

Valeria Correa-Carranza
Guillermo Rosario-Méndez
Manuel Castillejos-López
Juan Luis Chávez-Pacheco
Cesar Galván-Díaz
Luz María Torres-Espíndola

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1654783

903 views

Editorial

Published on 28 Jan 2026

Editorial: Advancement of RWD/RWE utilization for enhancing drug development and benefit/risk assessment

in Pharmacoepidemiology

Yoshiaki Uyama
Anick Bérard
K. Arnold Chan

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1787363

584 views

Original Research

Published on 28 Jan 2026

Innovative dual-functional hybrid cationic PEGylated proniosomes as a smart nano-platform for Boosted vaginal delivery: multi-level in-vitro, ex-vivo, microbiological, and in-vivo studies

in Experimental Pharmacology and Drug Discovery

Sadek Ahmed
Osama Saher
Heba Attia
Abdurrahman M. Fahmy
Islam M. Adel

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1746918

638 views

Original Research

Published on 28 Jan 2026

Prediction of infliximab and anti-drug antibody concentrations in patients with inflammatory bowel disease using machine learning models with real-world data from a prospective cohort study

in Gastrointestinal and Hepatic Pharmacology

Minjung Kim
Joo Hye Song
Sung Noh Hong
Myeong Gyu Kim
Eun Ran Kim
Dong Kyung Chang
Young-Ho Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1731193

546 views

Review

Published on 28 Jan 2026

Preparation, immunological and pharmacological effects of flavonoids in Scutellariae radix: a review

in Ethnopharmacology

Haixia Chen
Yumin Wei
Jing Song
Yue Yang
Yanli Chen
Jiteng Sun
Daoming Bai
Zhiqiang Sun
Mingze Wu
Xiaomei Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1732322

581 views

Original Research

Published on 28 Jan 2026

Integrating traditional omics and AI-driven approaches for discovery and validation of novel MicroRNA biomarkers and therapeutic targets in thyroid cancer

in Experimental Pharmacology and Drug Discovery

Yi Wan
Dan Xie
Min Zhang
Shiyu Yang
Zhantian Zhang
Xiaomin Fu
Meiling Wang
Yongfu Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1727032

589 views

Systematic Review

Published on 28 Jan 2026

The efficacy of artesunate in animal models of sepsis: a systematic review and meta-analysis

in Inflammation Pharmacology

Wenzhan Xie
Linxi Lv
Tian Wang
Jialong Wei
Yanshan Gui
Bing Han
Laixian Zhou
Hui Feng
Wei Gu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1748083

630 views

Original Research

Published on 28 Jan 2026

A study on the availability of national centralized drug procurement in regions with different levels of economic development: an investigation and analysis of 31 provincial-level administrative regions in China

in Drugs Outcomes Research and Policies

Wei Lu
Yan Qiao
Hongdou Chen
Wei Li
Menglei Wang
Chan Yuan
Qingqing Yang
Yanquan Lin
Yuanyuan Zhao
Lu Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1652715

641 views

Original Research

Published on 28 Jan 2026

Early treatment with nootkatone prevents pressure overload-induced ventricular remodeling and heart failure

in Cardiovascular and Smooth Muscle Pharmacology

Zhongyuan Liu
Zixin Zhou
Wenjing Yuan
Jiajin Li
Jie Tian
Mi Li
Junjun Quan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1702627

490 views

29,525 articles

articles

Network Meta-Analysis of Pharmacological Treatments for Idiopathic Pulmonary Fibrosis: Evaluating Effects on Lung Function

Magnesium Sulfate Pharmacology for Maternal and Critical-Care Indications: Mechanisms, Pharmacokinetics, and the Therapeutic Window

Profibrotic predictive toxicology in the lung

Eubacterium sp. mediates the anti-Obesity effect of Lotus leaf extract via Brown Adipose Tissue activation and White Fat Browning

Danshen (Salvia miltiorrhiza) extract in Spinal Cord Injury (SCI): A Systematic Review and Meta-Analysis

The Impact of Nutritional, Environmental, and Lifestyle Factors on Neurological Disorders: Therapeutic Implications and Mechanistic Insights

Different treatments for Crohn's disease complicated with severe acute lower Gastrointestinal bleeding: Infliximab therapy is critical and cannot be ignored

Wedelolactone, a natural coumestan with multiple pharmacological effects

Therapeutic effects of Lactobacillus rhamnosus, thymol and their combination against neurotoxicity in propionic acid (PA)-induced autistic rats: insights into the role of the Nrf2/HO-1, Wnt3/β-catenin/GSK3β BDNF/p-TrkB/CREB, pI3K/Akt/mTOR, AMPK/SIRT-1, and PERK/CHOP/Bcl-2 pathways

Editorial: Food derived bioactive metabolites: unlocking their potential health benefits and medical potential

Real-world data on the abuse potential of medications for the treatment of insomnia: a disproportionality analysis of the FAERS database

Troxerutin, a herbal metabolite with antidiabetic and antihypercholesterolemic potential, regulates metabolic gene activity in male diabetic rats

NAPQI adducts in patients with selective hypersensitivity to acetaminophen

Recent advances in mitochondria-targeted porphyrin-based metal-organic frameworks for enhanced cancer therapy

Efficacy and safety of midazolam versus dexmedetomidine in mechanically ventilated intensive care unit patients: a systematic review and meta-analysis

Targeted therapies in pediatric B-Cell acute lymphoblastic leukemia: mechanisms, efficacy, and future directions

Editorial: Advancement of RWD/RWE utilization for enhancing drug development and benefit/risk assessment

Innovative dual-functional hybrid cationic PEGylated proniosomes as a smart nano-platform for Boosted vaginal delivery: multi-level in-vitro, ex-vivo, microbiological, and in-vivo studies

Prediction of infliximab and anti-drug antibody concentrations in patients with inflammatory bowel disease using machine learning models with real-world data from a prospective cohort study

Preparation, immunological and pharmacological effects of flavonoids in Scutellariae radix: a review

Integrating traditional omics and AI-driven approaches for discovery and validation of novel MicroRNA biomarkers and therapeutic targets in thyroid cancer

The efficacy of artesunate in animal models of sepsis: a systematic review and meta-analysis

A study on the availability of national centralized drug procurement in regions with different levels of economic development: an investigation and analysis of 31 provincial-level administrative regions in China

Early treatment with nootkatone prevents pressure overload-induced ventricular remodeling and heart failure