Frontiers in Pharmacology

Original Research

Published on 14 Apr 2025

Mirabegron induces selective changes in the faecal microbiota of HFHFr rats without altering bile acid composition

in Gastrointestinal and Hepatic Pharmacology

Roger Bentanachs
Lluïsa Miró
Patricia Ramírez-Carrasco
Rosa M. Sánchez
Manuel Bernabeu
Concepció Amat
Marta Alegret
Anna Pérez-Bosque
Núria Roglans
Juan C. Laguna

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1547749

331 views

Clinical Trial

Published on 14 Apr 2025

Effects of esketamine–sufentanil for patient-controlled intravenous analgesia in women following cesarean section: A randomized clinical trial

in Obstetric and Pediatric Pharmacology

Yanping Zhao
Lin Liu
Yi Hou
Jiaming Fan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1579633

316 views

Review

Published on 14 Apr 2025

Integrative approaches to depression in end-stage renal disease: insights into mechanisms, impacts, and pharmacological strategies

in Neuropharmacology

Cheng Yuan
Fengpei Chang
Hongfu Zhai
Jiayin Du
Danqin Lu
Haoli Ma
Xiaoyan Wu
Ping Gao
Lihua Ni

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559038

333 views

Original Research

Published on 14 Apr 2025

Optimization and impact of an evidence-based pre-audit prescription decision system in primary healthcare settings

in Drugs Outcomes Research and Policies

Xiao-Hui Yue
Lei Yang
Jing-Jing Zhong
Hong-Mei Liu
Dan Wang
Xue Tao
Gao-Feng Zheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1491810

340 views

Correction

Published on 14 Apr 2025

Corrigendum: Natural products targeting AMPK signaling pathway therapy, diabetes mellitus and its complications

in Ethnopharmacology

Min Li
Lu Ding
Liyuan Cao
Zepeng Zhang
Xueyan Li
Zirui Li
Qinjing Xia
Kai Yin
Siyu Song
Zihan Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1604573

146 views

Original Research

Published on 14 Apr 2025

Development of an adipocyte differentiation protocol using 3T3-L1 cells for the investigation of the browning process: identification of the PPAR-γ agonist rosiglitazone as a browning reference drug

in Translational Pharmacology

Lorenzo Flori
Giulia Galgani
Giorgia Bray
Chiara Ippolito
Cristina Segnani
Carolina Pellegrini
Valentina Citi
Nunzia Bernardini
Alma Martelli
Vincenzo Calderone

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1546456

364 views

Original Research

Published on 14 Apr 2025

Cardiac protection of wogonin in mice with pulmonary fibrosis by regulating Sirt1/ γ-H2AX pathway

in Cardiovascular and Smooth Muscle Pharmacology

Libo Wang
Fei Lin
Runran Miao
Tianhao Zhao
Yuan Liu
Lin Yang
Min Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1551141

346 views

Original Research

Published on 14 Apr 2025

Dehydroleucodine exerts an antiproliferative effect on human Burkitt’s lymphoma Daudi cells via SLC7A11-mediated ferroptosis

in Pharmacology of Anti-Cancer Drugs

Rui Shen
Fang Cheng
Rui Guo
Wenjing Wang
Xiaolong Yang
Yemiao Chen
Yaokai Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1572364

252 views

Editorial

Published on 14 Apr 2025

Editorial: Exploring the key targets and compounds that manipulate brain neurocircuits against mental disorders and psychiatric volume II

in Neuropharmacology

Weijie Xie
Yuan Li
Song Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1601881

232 views

Original Research

Published on 14 Apr 2025

5-methoxytryptophan ameliorates renal ischemia/reperfusion injury by alleviating endoplasmic reticulum stress-mediated apoptosis through the Nrf2/HO-1 pathway

in Renal Pharmacology

Shaona Li
Hongjuan Yang
Bing Zhang
Lingyu Li
Xiangkun Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1506482

207 views

Case Report

Published on 14 Apr 2025

Case Report: A novel ELMOD3-ALK and EML4-ALK double-fusion responses to neoadjuvant alectinib in a lung adenocarcinoma patient

in Pharmacology of Anti-Cancer Drugs

Kaili Huang
Wen Li
Yinyin Xue
Lei Peng
Qiang Wu
Qinghua Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1515826

255 views

Clinical Trial

Published on 14 Apr 2025

Bioequivalence and safety assessment of sorafenib tosylate tablets in healthy Chinese subjects under fasting conditions

in Drug Metabolism and Transport

Zhaoyu Wang
Hong Peng
Yun Zhang
Xijing Chen
Jiye A

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1470095

250 views

Original Research

Accepted on 11 Apr 2025

Anti-inflammatory effect and mechanism of stytontriterpene D on RAW264.7 cells and zebrafish

in Inflammation Pharmacology

Chuqin Yu
Gao Qiu
Quanwei Xie
Xiangying Liu
Zonghao Lin
Feng Wang
Lei Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559022

338 views

Original Research

Accepted on 11 Apr 2025

Antibacterial activity of tamoxifen derivatives against methicillinresistant Staphylococcus aureus

in Pharmacology of Infectious Diseases

Irene Molina Panadero
Javier Falcón Torres
Abdelkrim Hmadcha
Salvatore Princioto
Luigi Cutarella
Mattia Mori
Sabrina Dallavalle
Michail Christodoulou
Younes Smani

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1549288

194 views

Original Research

Accepted on 11 Apr 2025

Canagliflozin alleviates progestin resistance by suppressing RARβ/CRABP2 signaling in THRB knockout endometrial cancer cells

in Experimental Pharmacology and Drug Discovery

Ye Yang
Jieyun Zhou
Qiaoying Lv
Qicheng Ni
Baichun Hu
Yulong Wang
Shuning Qu
Guoting Li
Wenjie Yang
Ruihua Zhong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1573032

144 views

Original Research

Accepted on 11 Apr 2025

Synergistic Effects of Retinol and Retinyl Palmitate in Alleviating UVB-Induced DNA Damage and Promoting the Homologous Recombination Repair in Keratinocytes

in Experimental Pharmacology and Drug Discovery

Jiangming Zhong
Ling Liang
Nan Zhao
Jing Wang
Peng Shu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562244

179 views