Frontiers in Pharmacology

Original Research

Published on 09 Dec 2025

Pharmacokinetics and pharmacodynamics of cannabigerol (CBG) in the C57BL/6Crl mouse

in Experimental Pharmacology and Drug Discovery

Ayat Zagzoog
Kenzie Halter
Nini Ha
Alayna M. Jones
Rachel Andres
Andy Kim
Deborah Michel
Jane Alcorn
Robert B. Laprairie

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1672098

1,016 views

Editorial

Published on 09 Dec 2025

Editorial: Innovative approaches for wound treatment

in Integrative and Regenerative Pharmacology

Junxiao Zhang
Shenglin Geng
Guojuan Fan
Jinlong Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1738213

382 views

Review

Published on 09 Dec 2025

Pharmacological effects and application prospects of mussel adhesive proteins

in Translational Pharmacology

Junsha An
Zengmiao Hou
Jiaqi Li
Qian Bi
Shile Huang
Cheng Peng
Fu Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1704475

708 views

Original Research

Published on 09 Dec 2025

Protective effects of an Fc-engineered PD-L1 fusion protein in a spontaneous abortion model and a Th17 cell–induced pregnancy loss model

in Experimental Pharmacology and Drug Discovery

Guangyao Li
Tiantian Wang
Dan Tan
Yamin Jin
Xuemei Zhou
Hongru Ai
Xinya Zheng
Xiaochen Ren
Shi Hu
Changhai Lei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1703805

440 views

Original Research

Published on 09 Dec 2025

Phoxim induces neurotoxicity and intestinal damage in Caenorhabditis elegans

in Predictive Toxicology

Mengyuan Zhang
Xin Zhao
Hua Bai
Qi Wang
Wei Zou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657527

728 views

Original Research

Published on 09 Dec 2025

Impact of different doses of rivaroxaban on clinical outcomes in elderly patients with non-valvular atrial fibrillation: a real-world study

in Cardiovascular and Smooth Muscle Pharmacology

Juan Yu
Zufeng Zhang
Qingru Yuan
Haobing Hu
Huimin Li
Meifang Huang
Youlin Mao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1714318

588 views

Systematic Review

Published on 09 Dec 2025

Is tranexamic acid effective for all traumatic brain injury patients? a severity based systematic review and meta-analysis

in Neuropharmacology

Wentao Bian
Mengxia Qi
Lu Ding
Yixuan Lu
Kangling Yan
Ziqi Wang
Jiancheng Zhang
Ping Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1677936

666 views

Original Research

Published on 09 Dec 2025

Disrupting cell death: ferroptosis and pyroptosis inhibition in hepatic ischemia-reperfusion injury via modulation of GPX4 and cGAS pathways by deferoxamine and octreotide

in Gastrointestinal and Hepatic Pharmacology

Rasha A. Tawfiq
Yasmeen M. Attia
Hameis M. Sleem
Mai El-Sayed Ghoneim

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1610718

787 views

Conceptual Analysis

Published on 09 Dec 2025

The night is dark and full of hesitation. The latest step in the legal trajectory of assisted suicide in Italy: through tentative judicial openings, bioethical contradictions and the Parliament’s deafness

in Drugs Outcomes Research and Policies

Paola Frati
Marco Albore
Eleonora Micaela Ertola
Sossio Del Prete
Letizia Sorace
Raffaele La Russa
Giorgio Bolino

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1520136

521 views

Editorial

Published on 09 Dec 2025

Editorial: Efficacy and mechanism of herbal medicines and their functional compounds in preventing and treating cardiovascular diseases and cardiovascular disease risk factors-Volume II

in Ethnopharmacology

Tiantian Meng
Yuqing Zhang
Jie Wang
Chen Huei Leo
Zhongfeng Li
Jian Zhang
Kuo Gao
Qingyong He

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1742260

509 views

Original Research

Published on 09 Dec 2025

Ethnobotany, chemical analysis, and antiglycation activity of Elsholtzia species from Northern Thailand

in Ethnopharmacology

Angkhana Inta
Pitchaya Mungkornasawakul
Lalida Shank
Wittaya Pongamornkul
Yinxian Shi
Yao Fu
Ruyu Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1673250

489 views

Original Research

Published on 09 Dec 2025

Cryptotanshinone targets tumor-immune-microbiome axis to suppress colorectal cancer

in Ethnopharmacology

Zhenya Yang
Mengting Zhou
Fenglin Luo
Shiqi Feng
Yu Tan
Qiqian Wang
Zeneng Cheng
Ruirong Tan
Rui Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1667500

853 views

Review

Accepted on 08 Dec 2025

Pharmacological and Bioactive Properties of Artemisia argyi H. Lév. & Vaniot Essential Oil: A Review

in Ethnopharmacology

Yanqin Lu
Qing Gao

Frontiers in Pharmacology

268 views

Original Research

Accepted on 08 Dec 2025

Phytochemical characterization and pharmacological evaluation of aerial and root parts of Dalea pazensis Rusby [Fabaceae]

in Ethnopharmacology

MARIANA ANDREA PERALTA
Einy Nallybe Bedoya Aguirre
Melisa Negro
Javier Echeverría
Maria Daniela Santi
Maria Gabriela Ortega

Frontiers in Pharmacology

106 views

Original Research

Accepted on 08 Dec 2025

Cerebrolysin, hemorrhagic transformation, and anticoagulation timing after reperfusion therapy in stroke: post hoc secondary analysis of the CEREHETIS trial

in Neuropharmacology

Mikhail N. Kalinin
Dina R. Khasanova

Frontiers in Pharmacology

399 views

Original Research

Accepted on 08 Dec 2025

Pharmacological Characterization and Preclinical Evaluation of 11h: A Novel, Brain-Penetrant PDE4 Inhibitor for Neurological Disorders

in Experimental Pharmacology and Drug Discovery

Jacob Lackovic
Sougata Dey
Sara Jane Ward
Nigel H Greig
David Tweedie
Nassim Beiranvand
Uksha Saini
Dev Chatterjee
Atul Varadhachary

Frontiers in Pharmacology

158 views

Review

Accepted on 08 Dec 2025

Targeting the AMP-activated protein kinase pathway: the active metabolites of botanical drugs represent potential strategies for treating metabolic-associated fatty liver disease

in Ethnopharmacology

Liang Qi
AI LI
Lin He
Liang-Chen Wang
Jiaolong Wang

Frontiers in Pharmacology

142 views

Editorial

Accepted on 08 Dec 2025

Editorial: Prevention and Treatment of Skin Diseases

in Experimental Pharmacology and Drug Discovery

ROSA DI LIDDO
Francesca Caroppo
Masaoki Kawasumi
Barbara Zavan

Frontiers in Pharmacology

270 views

Original Research

Accepted on 08 Dec 2025

Refined Target-mediated Drug Disposition Modeling of the Anti-Tissue Factor Pathway Inhibitor Antibody MG1113 in Cynomolgus Monkeys and Rabbits

in Translational Pharmacology

Heechun Kwak
Yoo-Seong Jeong
Jiyoung Kim
Minsoo Lee
Seonyoung Byoun
Yasunori Aoki
Suk-Jae Chung
Wooin Lee

Frontiers in Pharmacology

193 views

Systematic Review

Accepted on 08 Dec 2025

Subcutaneous versus Intravenous Trastuzumab for HER2-Positive Breast Cancer: A Global Systematic Review and Meta-Analysis with a Cost-Minimization Analysis from the Chinese Healthcare System Perspective

in Drugs Outcomes Research and Policies

Zheng Zeng
Li Zhong
Lin Zhu
Zefeng Zhu
Luqin Liao
Yuening Cao
Da Zheng
Guidong Huang
Wei CHEN
Lin Zhang

Frontiers in Pharmacology

141 views

Review

Accepted on 08 Dec 2025

Bile Acids as Therapeutic Agents

in Gastrointestinal and Hepatic Pharmacology

Brandon Vu
Ryo Kawamoto
Priscila Villalba-Davila
Xinzhong Dong
Wikrom Karnsakul

Frontiers in Pharmacology

180 views

Original Research

Accepted on 08 Dec 2025

Preclinical pharmacological profiles of cofrogliptin, a novel and bi-weekly DPP-4 inhibitor

in Experimental Pharmacology and Drug Discovery

Xiaoli Gou
Caixia Dou
Pingming Tang
Xiaoxiao Zheng
Chen Zhang
Jianmin Wang
Qingyuan Meng
Ju Wang

Frontiers in Pharmacology

139 views

Case Report

Accepted on 08 Dec 2025

Molecular Guided Therapy Leading to Exceptional Response in Relapsed Osteosarcoma

in Pharmacology of Anti-Cancer Drugs

Elizabeth Wert
Leah Menachery
Jeremy Hengst
Tarlan Arjmandi
Abhinav Beeravally Nagulapally
Valerie Brown
Divya Gandra
Giselle Sholler
Smita Dandekar

Frontiers in Pharmacology

141 views

Original Research

Accepted on 08 Dec 2025

A Life-Threatening Crisis: The Unique Symphony of Aconitine Poisoning-Induced Cardiac Arrest and Hepatic Portal Venous Gas

in Gastrointestinal and Hepatic Pharmacology

Yonghong Wang
Wei Pan
Wentao Tao
Junping Zhu
YANG Xianyi

Frontiers in Pharmacology

29,106 articles

articles

Pharmacokinetics and pharmacodynamics of cannabigerol (CBG) in the C57BL/6Crl mouse

Editorial: Innovative approaches for wound treatment

Pharmacological effects and application prospects of mussel adhesive proteins

Protective effects of an Fc-engineered PD-L1 fusion protein in a spontaneous abortion model and a Th17 cell–induced pregnancy loss model

Phoxim induces neurotoxicity and intestinal damage in Caenorhabditis elegans

Impact of different doses of rivaroxaban on clinical outcomes in elderly patients with non-valvular atrial fibrillation: a real-world study

Is tranexamic acid effective for all traumatic brain injury patients? a severity based systematic review and meta-analysis

Disrupting cell death: ferroptosis and pyroptosis inhibition in hepatic ischemia-reperfusion injury via modulation of GPX4 and cGAS pathways by deferoxamine and octreotide

The night is dark and full of hesitation. The latest step in the legal trajectory of assisted suicide in Italy: through tentative judicial openings, bioethical contradictions and the Parliament’s deafness

Editorial: Efficacy and mechanism of herbal medicines and their functional compounds in preventing and treating cardiovascular diseases and cardiovascular disease risk factors-Volume II

Ethnobotany, chemical analysis, and antiglycation activity of Elsholtzia species from Northern Thailand

Cryptotanshinone targets tumor-immune-microbiome axis to suppress colorectal cancer

Pharmacological and Bioactive Properties of Artemisia argyi H. Lév. & Vaniot Essential Oil: A Review

Phytochemical characterization and pharmacological evaluation of aerial and root parts of Dalea pazensis Rusby [Fabaceae]

Cerebrolysin, hemorrhagic transformation, and anticoagulation timing after reperfusion therapy in stroke: post hoc secondary analysis of the CEREHETIS trial

Pharmacological Characterization and Preclinical Evaluation of 11h: A Novel, Brain-Penetrant PDE4 Inhibitor for Neurological Disorders

Targeting the AMP-activated protein kinase pathway: the active metabolites of botanical drugs represent potential strategies for treating metabolic-associated fatty liver disease

Editorial: Prevention and Treatment of Skin Diseases

Refined Target-mediated Drug Disposition Modeling of the Anti-Tissue Factor Pathway Inhibitor Antibody MG1113 in Cynomolgus Monkeys and Rabbits

Subcutaneous versus Intravenous Trastuzumab for HER2-Positive Breast Cancer: A Global Systematic Review and Meta-Analysis with a Cost-Minimization Analysis from the Chinese Healthcare System Perspective

Bile Acids as Therapeutic Agents

Preclinical pharmacological profiles of cofrogliptin, a novel and bi-weekly DPP-4 inhibitor

Molecular Guided Therapy Leading to Exceptional Response in Relapsed Osteosarcoma

A Life-Threatening Crisis: The Unique Symphony of Aconitine Poisoning-Induced Cardiac Arrest and Hepatic Portal Venous Gas