Frontiers in Pharmacology

Clinical Trial

Accepted on 27 Jun 2025

Effects of the Efficacy of the Yi Shen Tiao Gan Formula on Aromatase Inhibitor Associated Musculoskeletal Syndrome: A randomized controlled trial

in Ethnopharmacology

Yan Zhang
Meiling Chu
Meina Ye
Yiqin Cheng
Hui Cong
Yulian Yin
Hongfeng Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1639714

453 views

Brief Research Report

Accepted on 27 Jun 2025

Comparison of associations suggests mainly distinct pools of genetic risk factors contribute to cisplatin-induced hearing loss and hearing difficulty in the general population

in Pharmacology of Anti-Cancer Drugs

Mohammad Shahbazi
Heather E. Wheeler
Xindi Zhang
Robert D. Frisina
Lois B. Travis
M. Eileen Dolan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1577072

331 views

Original Research

Accepted on 27 Jun 2025

Gastrodin reduces myocardial ischemia/reperfusion injury via Transgelin2/CNPase-mediated apoptosis regulation

in Cardiovascular and Smooth Muscle Pharmacology

Changyan Li
Peng Rao
Xiang Liu
Lin Yang
Yongliang Jiang
Gaosheng Yin
Shuangxiu Li
Ping Yang
Sun Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1604408

203 views

Original Research

Accepted on 27 Jun 2025

Dipeptidyl peptidase-4 enzyme inhibition and its impacts on hepatic preneoplasia: A new avenue for liver cancer management

in Drug Metabolism and Transport

Hebatollah Eitah
Rabab Sayed
yousreya maklad
amina Gamal el Din
khaled mahmoud
Ayman Elsahar
Amani Alhejely
Amal Abdulbaqi
Hanan Naeim

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559303

173 views

Systematic Review

Accepted on 27 Jun 2025

Effectiveness and Safety of Direct Oral Anticoagulants Versus Vitamin K Antagonists in Atrial Fibrillation Patients with Liver Disease: A Systematic Review and Meta-analysis

in Drugs Outcomes Research and Policies

Qiang Zhou
Xiang Liu
Shuyu Liu
Zhi-Chun Gu
Yanzi Wu
Yuansu Yang
Yingying Tao
Meng Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1620394

155 views

Original Research

Accepted on 27 Jun 2025

The GPR4 antagonist NE-52-QQ57 increases survival, mitigates the hyperinflammatory response and reduces viral load in SARS-CoV-2-infected K18-hACE2 transgenic mice

in Pharmacology of Infectious Diseases

Xin-Jun Wu
Karen A. Oppelt
Ming Fan
Mona A. Marie
Madison M. Swyers
Ashley J. Williams
Isabelle M. Lemasson
Rachel L. Roper
Paul Bolin
Li V. Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1549296

171 views

Original Research

Accepted on 27 Jun 2025

Anticandidal activity of Clinopodium chilense essential oil

in Ethnopharmacology

Iván J. Montenegro
Constanza Villarroel
Evelyn Muñoz
Valentina Silva
Alejandro Madrid

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1634250

127 views

Original Research

Accepted on 27 Jun 2025

Underlying Molecular Mechanisms of Rosa roxburghii Tratt. Polysaccharides: Cell Cycle Arrest and Apoptotic Induction in Hepatocellular Carcinoma

in Ethnopharmacology

Ziyan Yang
Zilin Li
Yuxing Liao
Cuixiang Zhang
Lijin Huang
Han Wang
Guihua Wang
Xueying Li
Guiyuan Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562336

147 views

Review

Accepted on 27 Jun 2025

From Traditional Remedy to Modern Therapy: A Comprehensive Review of Palmatine's Multi-Target Mechanisms and Ethnopharmacological Potential

in Ethnopharmacology

Zhoujing Shi
Lutuo Han
Yang Huasen
Geling Lu
Zhouying Shi
Ma Boyan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1624353

141 views

Original Research

Accepted on 27 Jun 2025

Clinical significance and gene prediction of a novel classification system based on tacrolimus concentration-to-dose ratio in the early post-liver transplant period

in Pharmacogenetics and Pharmacogenomics

Junwei Fan
Peihao Wen
Liyun Yuan
Yan Xia
Shijie Hu
Xiaoqing Zhang
Zhihai Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1614753

135 views

Systematic Review

Accepted on 27 Jun 2025

Bibliometric and Visual Analysis of Traditional Chinese Medicine Flavonoids in the Treatment of Obesity from 2004 to 2024

in Pharmacoepidemiology

Yuanyuan Yan
Baoyi Wu
Bo Zhang
Anxia Li
Pingping Liu
Yang Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545870

126 views

Original Research

Accepted on 27 Jun 2025

S-ketamine facilitates motor function recovery after brachial plexus root avulsion and reimplantation in mice

in Neuropharmacology

Ronghua Huang
Bingbiao Lin
Lingtai Yu
Qichen Luo
Hongyan Tian
Chenrui Li
Naili Wei
Shaohui Zhuang
Jian Chen
Yalan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1630158

145 views

Review

Accepted on 27 Jun 2025

Pharmacodynamics, pharmacokinetics, interactions with other drugs, toxicity and clinical effectiveness of proton pump inhibitors

in Drugs Outcomes Research and Policies

Łukasz Wołowiec
Joanna Osiak
Albert Jaśniak
Michał Janiak
Lidia Wydeheft
Magdalena Łukasiak
Małgorzata Pellowska
Grzegorz Grześk

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1507812

123 views

Case Report

Accepted on 27 Jun 2025

Case Report: Coadministration of TNF-α Blockade as an Effective Adjunctive Strategy in the Treatment of ANCA-Negative EGPA with Refractory Peripheral Neuropathy

in Respiratory Pharmacology

Dabin Tang
Yubao Jiang
Shuo Yang
Jiaxin Wei
Jingjing Xie
Jianyong Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1555377

129 views

Original Research

Accepted on 27 Jun 2025

A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma

in Experimental Pharmacology and Drug Discovery

Yue Fu
Weiyue Fang
Xiaohui Zhu
Fuqiang Qiu
Juncai Lai
Yangjin Xu
Bin Chen
Yang Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1605515

Original Research

Accepted on 27 Jun 2025

Evaluating the Risk of Osteoporosis-Related Adverse Events with Proton Pump Inhibitors: A Pharmacovigilance Study

in Gastrointestinal and Hepatic Pharmacology

Jingkai Di
Nan Yang
Yicong Zhao
Shuai Chen
Zijian Guo
Dongdong He
Chuan Xiang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1582908