Frontiers in Pharmacology

Original Research

Accepted on 08 Dec 2025

Donkey Milk-derived Exosomes Protect Against UVB Irradiation-Induced Ferroptosis in Skin Cells: In Vitro and In Vivo Evidence

in Experimental Pharmacology and Drug Discovery

Hang Tie
Jie Yu
Jie Cheng
Guangyuan Liu
Zhijie Cheng
Pengxiang Niu
Derui Xu
Xinyun Pei
Cong Wang

Frontiers in Pharmacology

230 views

Review

Accepted on 08 Dec 2025

Cycloastragenol in Inflammation-Related Diseases: Mechanisms, Pharmacokinetics, and Translational Prospects

in Inflammation Pharmacology

Chun Zhao
Xiuhua Yang
Man Yao
Xiaoxuan Song
Pilong He

Frontiers in Pharmacology

138 views

Review

Accepted on 08 Dec 2025

Signaling pathways of marine-derived natural products on lung injury: from the in vivo perspective

in Respiratory Pharmacology

Haitong Wang
Feng Qiu

Frontiers in Pharmacology

108 views

Case Report

Accepted on 08 Dec 2025

Hematologic immune-related adverse events in skin cancer patients treated with immune checkpoint inhibitors: a case series

in Pharmacology of Anti-Cancer Drugs

Rosa Falcone
Alessandra Frezzolini
Emanuele Bruni
Sofia Verkhovskaia
Maria Luigia Carbone
Francesca Romana Di Pietro
Paolo Chesi
Gabriele Piesco
Maria Cantonetti
Paolo Marchetti

Frontiers in Pharmacology

188 views

Original Research

Accepted on 08 Dec 2025

Targeted Lipidomics Meets Transcriptomics: How Cinobufagin Rewires Fatty Acid, Sphingolipid, and Glycerophospholipid Metabolism to Combat Hepatoma cell growth

in Pharmacology of Anti-Cancer Drugs

Wanjun Shao
Congying Yu
Rufei Xu
Xiaoqian Rong
Ailin Yang

Frontiers in Pharmacology

Review

Accepted on 08 Dec 2025

Advances in Research on the Effects of Medicinal and Edible Substances on Lung Cancer: An updated review

in Ethnopharmacology

Yang Ying
Lingli Jiang
Ke Li
Gemming Zhang
Junpeng Wang
Daorui Li

Frontiers in Pharmacology

Review

Published on 08 Dec 2025

Cost-effectiveness analysis of commercial Chinese polyherbal preparations for primary insomnia: based on network meta-analysis

in Ethnopharmacology

Sihong Yang
Fanya Yu
Xinghua Xiang
Chuchuan Wan
Yumeng Tan
Ning Ma
Yajing Li
Long Ge
Xing Liao
Hui Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1682173

525 views

Original Research

Published on 08 Dec 2025

Pterostilbene mitigates the senescence of human dermal fibroblast cells by enhancing mitochondrial quality

in Translational Pharmacology

Xinyu Zhou
Ning Wang
Jihua Wei
Guizhi Li
Zhengwei Lue
Chang Liu
Qi Bao
Zhe Feng
Minjie Zhang
Hu Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1732154

998 views

Original Research

Published on 08 Dec 2025

Selective cytotoxicity of Gomortega keule essential oil through a ROS-mediated pro-apoptotic mechanism

in Ethnopharmacology

Alejandro Madrid
Valentina Silva
Alessandra Russo
Alejandra Catalina Moller
Elizabeth Sánchez
Joan Villena
Carlos Jara-Gutiérrez
Iván Montenegro

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1722619

478 views

Correction

Published on 08 Dec 2025

Correction: DICAR/DICAR-JP exerts therapeutic effects in brain stroke via the miR-361-5p/PRMT1 pathway

in Translational Pharmacology

Zhijun Yu
Aihua Jiang
Kai Yang
Lin Zhan
Zifei Xiang
Li Chen
Zheng Kuai
Qiong Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1756716

371 views

Systematic Review

Published on 08 Dec 2025

Therapeutic efficacy and safety of Xuebijing in traumatic brain injury: systematic review and meta-analysis

in Ethnopharmacology

Yihan Sun
Jiaqi Li
Xinyue Cui
Meiyu Yu
Boying Xiao
Junyuan Lv
Ziqi Li
Zhijing Wei
Niaoyao He
Zhuoyu Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1669352

584 views

Original Research

Published on 08 Dec 2025

Validation of diagnostic screening test for pharmacogenomic targets for thiopurine drugs in indian pediatric acute lymphoblastic leukemia patients

in Obstetric and Pediatric Pharmacology

Gratial Theres Joseph
Sandeep Kumar Swain
Tejas Somwanshi
Aarishi Singh
Manpreet Kaur
Raj Kamal
Himanshu Dhanda
Prashant Kumar
Upasana Kaushik
Baseer Noor

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1714797

835 views

Original Research

Published on 08 Dec 2025

Effects of methylphenidate on children with attention deficit hyperactivity disorder: a study using clinical and multimodal approaches including go/no-go task and functional near-infrared spectroscopy

in Obstetric and Pediatric Pharmacology

Fang Shen
Hui Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1726716

759 views

Correction

Published on 08 Dec 2025

Correction: Neuroprotective role of carvacrol in ischemic brain injury: a systematic review of preclinical evidence and proposed TRPM7 involvement

in Neuropharmacology

Abdulrahman M. Khojah
Hussain Al Dera

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1751557

398 views

Original Research

Published on 08 Dec 2025

Nobiletin mitigates benign prostatic hyperplasia by suppressing prostate cell proliferation through regulation of cell cycle progression, signaling pathways, transcription factor activity, and the androgen-signaling axis

in Pharmacology of Anti-Cancer Drugs

Jun-Hui Song
Daeun Lee
Byungdoo Hwang
Seon-Kyung Hwang
Sumin Choo
Hyeon Ji Jeong
Hoon Kim
Byungyoon Cha
Seok-Joong Yun
Yung Hyun Choi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1661201

1,149 views

Original Research

Published on 08 Dec 2025

Moxibustion combined with chemotherapy inhibits gastric cancer growth by modulating the immunosuppressive microenvironment involving the Treg/IL-10/TGF-β1 axis

in Pharmacology of Anti-Cancer Drugs

Yong Wu
Li Ma
Mengying Mao
Yuling Leng
Xianyang Zhou
Heng Xu
Yanqi Ding
Wanrong Hao
Wanhui Dong
Yonglei Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1688182

715 views

Review

Accepted on 05 Dec 2025

Traditional Medicine in a Modern Light: A Scoping Review on the Osteoprotective Potential of Eucommia ulmoides

in Ethnopharmacology

Guiju Chen
Yuan Zhong WANG
Qin Wang
Bilin Liu
Qi He
Xia Huang
Kok Yong Chin

Frontiers in Pharmacology

826 views

Original Research

Accepted on 05 Dec 2025

Spectrum Mining of Immune Checkpoint Inhibitor-Related Cutaneous Toxicities and Analysis of Associated Factors Based on FAERS

in Pharmacoepidemiology

Siyao Ma

Frontiers in Pharmacology

172 views

Systematic Review

Accepted on 05 Dec 2025

Trends in Oncology Marketing Authorization Applications: A Five-Year Systematic Review

in Drugs Outcomes Research and Policies

Ricardo Basto
Siddartha Karaya
Alex Zwiers

Frontiers in Pharmacology

287 views

Review

Accepted on 05 Dec 2025

Natural Products Targeting the Immune-Metabolic Regulatory Network in Pulmonary Hypertension: Mechanisms, Classification, and Therapeutic Prospects

in Ethnopharmacology

Jianli Ma
Xiyu Cao
Xiuli Yang
Yi Zhu
Hualing Wang
YD Liu
Ke Chen
XIAO LIU
Chuantao Zhang

Frontiers in Pharmacology

169 views

Clinical Trial

Accepted on 05 Dec 2025

Dezocine and butorphanol for the prevention of sufentanil-induced cough: A randomized controlled trial investigating the impact of intravenous access site

in Respiratory Pharmacology

Ying Liu
Hong-Yan Ma
Jinghui Shi

Frontiers in Pharmacology

197 views

Original Research

Published on 05 Dec 2025

Impact of lymphocyte transformation test on the diagnostic accuracy of the culprit drug in drug-induced cytopenias: a case-control study

in Drugs Outcomes Research and Policies

Susana Martín-López
Olga Rogozina
Daniela Aguilar-Concepción
Miguel Álvarez-Montero
Ramón Pardo-Puras
Ibtissam Akatbach-Bousaid
María Jiménez-González
Ana Martínez Feito
Miguel González-Muñoz
Elena Ramírez

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1601450

938 views

Review

Published on 05 Dec 2025

Navigating hepatotoxicity of antibody-drug conjugates: from mechanistic insights to clinical and postmarketing evidence

in Pharmacology of Anti-Cancer Drugs

Yinuo Dong
Yang Zhi
Xiaoyun Li
Mingyang Ma
Minyan Ye
Sha Huang
Jieting Tang
Wei Zhong
Xiaohong Lei
Yimin Mao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1694436

1,172 views

Correction

Published on 05 Dec 2025

Correction: Transdermal administration of herbal essential oil alleviates high-fat diet-induced obesity by regulating metabolism and gut microbiota

in Experimental Pharmacology and Drug Discovery

Zu-Wen Ye
Qi-Yue Yang
Dong-Hua Yang
Qiao-Hong Lin
Xiao-Xia Liu
Feng-Qin Li
Fang-Fang Yan
Ping Luo
Si Qin
Fang Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1743063

394 views

29,106 articles

articles

Donkey Milk-derived Exosomes Protect Against UVB Irradiation-Induced Ferroptosis in Skin Cells: In Vitro and In Vivo Evidence

Cycloastragenol in Inflammation-Related Diseases: Mechanisms, Pharmacokinetics, and Translational Prospects

Signaling pathways of marine-derived natural products on lung injury: from the in vivo perspective

Hematologic immune-related adverse events in skin cancer patients treated with immune checkpoint inhibitors: a case series

Targeted Lipidomics Meets Transcriptomics: How Cinobufagin Rewires Fatty Acid, Sphingolipid, and Glycerophospholipid Metabolism to Combat Hepatoma cell growth

Advances in Research on the Effects of Medicinal and Edible Substances on Lung Cancer: An updated review

Cost-effectiveness analysis of commercial Chinese polyherbal preparations for primary insomnia: based on network meta-analysis

Pterostilbene mitigates the senescence of human dermal fibroblast cells by enhancing mitochondrial quality

Selective cytotoxicity of Gomortega keule essential oil through a ROS-mediated pro-apoptotic mechanism

Correction: DICAR/DICAR-JP exerts therapeutic effects in brain stroke via the miR-361-5p/PRMT1 pathway

Therapeutic efficacy and safety of Xuebijing in traumatic brain injury: systematic review and meta-analysis

Validation of diagnostic screening test for pharmacogenomic targets for thiopurine drugs in indian pediatric acute lymphoblastic leukemia patients

Effects of methylphenidate on children with attention deficit hyperactivity disorder: a study using clinical and multimodal approaches including go/no-go task and functional near-infrared spectroscopy

Correction: Neuroprotective role of carvacrol in ischemic brain injury: a systematic review of preclinical evidence and proposed TRPM7 involvement

Nobiletin mitigates benign prostatic hyperplasia by suppressing prostate cell proliferation through regulation of cell cycle progression, signaling pathways, transcription factor activity, and the androgen-signaling axis

Moxibustion combined with chemotherapy inhibits gastric cancer growth by modulating the immunosuppressive microenvironment involving the Treg/IL-10/TGF-β1 axis

Traditional Medicine in a Modern Light: A Scoping Review on the Osteoprotective Potential of Eucommia ulmoides

Spectrum Mining of Immune Checkpoint Inhibitor-Related Cutaneous Toxicities and Analysis of Associated Factors Based on FAERS

Trends in Oncology Marketing Authorization Applications: A Five-Year Systematic Review

Natural Products Targeting the Immune-Metabolic Regulatory Network in Pulmonary Hypertension: Mechanisms, Classification, and Therapeutic Prospects

Dezocine and butorphanol for the prevention of sufentanil-induced cough: A randomized controlled trial investigating the impact of intravenous access site

Impact of lymphocyte transformation test on the diagnostic accuracy of the culprit drug in drug-induced cytopenias: a case-control study

Navigating hepatotoxicity of antibody-drug conjugates: from mechanistic insights to clinical and postmarketing evidence

Correction: Transdermal administration of herbal essential oil alleviates high-fat diet-induced obesity by regulating metabolism and gut microbiota