Frontiers in Pharmacology

Original Research

Accepted on 26 Jun 2025

c-MYC mRNA destabilization inhibited lethal pancreatic cancer in-vivo with significant survival outcomes

in Translational Pharmacology

Jigme P Dorji
Queenie Chen
Sandali G Perera
Fizza Aijaz
Petvy Li
Hiroshi Matsui
Chidiebere Awah

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1630476

185 views

Original Research

Accepted on 26 Jun 2025

Evaluation of the protective effect of quercetin and luteolin against ciprofloxacin-and chloramphenicol-induced oxidative stress in blood cells: Impact on antimicrobial activity

in Ethnopharmacology

Pamela Soledad Bustos
Javier Echeverria
Paulina Laura Páez
Maria Gabriela Ortega

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1626058

100 views

Mini Review

Accepted on 26 Jun 2025

Mini review: Ethnopharmacology and Phytochemistry of the Tropical American family Marcgraviaceae

in Ethnopharmacology

Ana Francis Carballo Arce
Luis Roberto Villegas-Peñaranda
Raúl Esteban Garro-Álvarez
Yohana Alfaro-Ureña
Manuel Sandoval-Barrantes
Martha Mullaly
John Thor Arnason

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1622814

Original Research

Published on 26 Jun 2025

Pedunculoside targets P2X7R to protect against myocarditis by regulating the NLRP3/PIP2/MAPK signaling pathway

in Cardiovascular and Smooth Muscle Pharmacology

Youqiong Zhuo
Jia He
Qin-Qin Wang
Yuntian Xiao
Xiaoyun Xie
Lina Liu
Shilin Yang
Jingjing Li
Renyikun Yuan
Hongwei Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1589298

512 views

Review

Published on 26 Jun 2025

Ethnobotany, phytochemistry, pharmacology and toxicity of Hagenia abyssinica (Bruce) J.F.Gmel.: a review

in Ethnopharmacology

Guohui Shi
Linlin Ni
Yang Zhang
Zhizi Qu
Xiaoni Kong
Honglei Zhou
Yan Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1593724

360 views

Systematic Review

Published on 26 Jun 2025

Compound Xuanju capsules combined with phosphodiesterase-5 inhibitors as a new strategy for erectile dysfunction: a meta-analysis and trial sequential analysis

in Ethnopharmacology

Ronghui Li
Min Liao
Yunfeng Yu
Bing Guo
Rong Yu
Qinghu He
Guomin Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1537789

466 views

Original Research

Published on 26 Jun 2025

Drug-associated hearing impairment in children: a disproportionality analysis of the FDA adverse event reporting system

in Pharmacoepidemiology

Jinfeng Liu
Junyi Tan
Qinli Xiao
Yingtao Bai
En Chang
Chun Su
Yuxun Wei
Hu Zhong
Wei Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532461

579 views

Original Research

Published on 26 Jun 2025

i-DENV: development of QSAR based regression models for predicting inhibitors targeting non-structural (NS) proteins of dengue virus

in Experimental Pharmacology and Drug Discovery

Sakshi Gautam
Anamika Thakur
Manoj Kumar

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1605722

599 views

Original Research

Published on 26 Jun 2025

Influence of probiotics and deoxycholate on azathioprine transport in the PAMPA model: insights into pharmacomicrobiomics and interindividual variability in drug response

in Drug Metabolism and Transport

Maja Đanić
Nebojša Pavlović
Natalija Dedić
Dragana Zaklan
Slavica Lazarević
Bojan Stanimirov
Momir Mikov

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1608110

365 views

Original Research

Published on 26 Jun 2025

Baicalein from Scutellaria baicalensis mitigates oxidative stress through the IIS pathway in a C. elegans model of ulcerative colitis

in Ethnopharmacology

Wei Wang
Xiaoyu Fu
Jianing Xu
Weiguang Lv
Shengnan Han
Yi Wang
Yu Xia
Jing Han
Ke Li
Chenggang Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592244

389 views

Review

Published on 26 Jun 2025

Deguelin’s Anticancer Bioactivity: Challenges and Opportunities in Medicinal Chemistry

in Experimental Pharmacology and Drug Discovery

Wenjie Jiang
Jing Zeng
Li Guo
Jianyou Shi
Yang Lei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1571452

411 views

Review

Published on 26 Jun 2025

Gastrointestinal stromal tumors with the use of ripretinib and sunitinib: real-world adverse event analysis based on the FDA adverse event reporting system (FAERS)

in Predictive Toxicology

Xinzhen Che
Yong Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561937

354 views

Original Research

Published on 26 Jun 2025

Geum japonicum Thunb. exhibits anti-platelet activity via the regulation of cyclic guanosine monophosphate

in Ethnopharmacology

Yuan Yee Lee
Abdul Wahab Akram
Young-Hee Kim
Muhammad Irfan
Sung Dae Kim
Evelyn Saba
Tae Wan Kim
Bong-Sik Yun
Man Hee Rhee

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1538417

383 views

Original Research

Published on 26 Jun 2025

Effects of Dendrobium officinale Kimura & Migo flower flavonoids on cognitive function by regulating gut microbiota

in Ethnopharmacology

Nanzhi Hu
Kaiyue Wang
Xing Ge
Xin Zhang
Xiaojie Zheng
Shifang Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562775

427 views

Review

Published on 26 Jun 2025

Advances in clinical applications of microneedle

in Drug Metabolism and Transport

Kequan Chen
Xinyu Sun
Yangkaiyuan Liu
Shiyu Li
Dianhuai Meng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1607210

662 views

Review

Published on 26 Jun 2025

Oxidative stress in ARDS: mechanisms and therapeutic potential

in Respiratory Pharmacology

Fengyun Wang
Ruiqi Ge
Yun Cai
Mingrui Zhao
Zhen Fang
Jingguo Li
Chengzhi Xie
Mei Wang
Wanyue Li
Xiaozhi Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1603287

448 views