Frontiers in Pharmacology

Original Research

Published on 01 Jul 2025

Antihypertensive medications and cancer risk: Evidence from 0.27 million patients with newly diagnosed hypertension

in Pharmacoepidemiology

Huan Yu
Zhike Liu
Yiqun Wu
Liuyan Zheng
Kun Wang
Jingxian Wu
Huairong Wang
Kexin Ding
Ruotong Yang
Huziwei Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559604

190 views

Mini Review

Published on 01 Jul 2025

Clinical characterization and management of persons with comorbid epilepsy and depression: an expert opinion paper

in Neuropharmacology

Gaia Sampogna
Roberto Brugnoli
Giuseppe Didato
Maurizio Elia
Edoardo Ferlazzo
Gianluca Serafini
Giampaolo Vatti
Umberto Volpe
Flavio Villani
Gabriele Sani

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592650

129 views

Clinical Trial

Published on 01 Jul 2025

A full-spectrum Boswellia serrata extract with enhanced bioavailability, and its co-delivered system with curcumin alleviate pain and stiffness associated with moderate spondylitis: a randomized double-blind, placebo-controlled, 3-arm study

in Ethnopharmacology

K. Mamatha
Prathibha Prabhakaran
S. Syam Das
Manu Kanjoormana Aryan
Jestin Thomas

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1577429

589 views

Editorial

Published on 01 Jul 2025

Editorial: Pharmacogenomics for improving drug safety and efficacy in cancer

in Pharmacogenetics and Pharmacogenomics

Zhiyao He
Xuewei Fu
Zhijie Xu
Omar Alshargi
Roberto Rodríguez-Labrada
Xiao-Bo Zhong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1649258

136 views

Original Research

Published on 01 Jul 2025

Glutamatergic mechanisms in early salience processing

in Neuropharmacology

Denise Elfriede Liesa Lockhofen
Nils Hübner
Ranjan Debnath
Karl Philipp Rumpf
Michael Sander
Matthias Wolff
Daniel Luxi
Lukas Roller
Christoph Mulert

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1601797

136 views

Systematic Review

Accepted on 30 Jun 2025

Drug Tapering in Animal Research: A Scoping Review

in Experimental Pharmacology and Drug Discovery

Yatong Zhang
Mengrui Chen
Tongtong Jiang
Qianfang Fu
Rong Ma
Lianghui Nie
Yuqiong You
Shuqi Gao
Ping Rong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1544784

Review

Accepted on 30 Jun 2025

High-mobility group box 1 in acute kidney injury

in Renal Pharmacology

Xuan Li
Guilin Jing
Zhentao Guo
Zhaoan Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1618971

Original Research

Accepted on 30 Jun 2025

What is the best clinical management strategies for cardiomyopathy? an umbrella review of systematic review and meta-analysis

in Cardiovascular and Smooth Muscle Pharmacology

Wanru Cheng
Jing Wang
Jie Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1544121

Opinion

Accepted on 30 Jun 2025

The Rho/MRTF-Pirin Axis: A Promising Target for Overcoming Melanoma Drug Resistance

in Pharmacology of Anti-Cancer Drugs

Xiaoyan Chen
Junfeng Zhang
Jiuhu Li
Zhi Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1571933

Review

Accepted on 30 Jun 2025

Application of cell-derived vesicle-based biomimetic drug delivery system in tumor therapy

in Drug Metabolism and Transport

Yan Mei
Maochang Liu
Meng Mei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1632361

Original Research

Accepted on 30 Jun 2025

Fucoxanthin Inhibits the Proliferation of MOLM13 Cells by Targeting AKT to Disrupt Glucose Metabolism

in Experimental Pharmacology and Drug Discovery

Tingting Niu
Ying Chen
Mengmeng Sun
Cong Shi
Duobing Zou
Wei Wu
Yuzhan Chen
Juanjuan Chen
Haimin Chen
Guifang Ouyang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1601281

Original Research

Accepted on 30 Jun 2025

Machine Learning-Enhanced Discovery of tsRNA-mRNA Regulatory Networks: Identifying Novel Diagnostic Biomarkers and Therapeutic Targets in Breast Cancer

in Experimental Pharmacology and Drug Discovery

Zhongling Ma
Rui Wang
Ming Yuan
Bo Wang
Li Li
Tianfu Zhao
Xinhan Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1640192

Original Research

Accepted on 30 Jun 2025

Calycosin suppresses the activating effect of granulocyte-macrophage-colonystimulating factor-producing T helper cells on macrophages in experimental

in Cardiovascular and Smooth Muscle Pharmacology

Xiaofang Xiong
Wei Huang
Xuexue Yang
Xun Wang
Beibei Wu
Dongsheng Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1607349

Original Research

Accepted on 30 Jun 2025

The effects of Shenkang suppository on kidney function and gut microbiota in nondialysis patients with chronic kidney disease stages 3-4: A randomized controlled trial

in Renal Pharmacology

Weiwei Zhang
Xin Zhang
Shuang Xu
Yousuf Abdulkarim Waheed
Yizhou Xu
Shulin Li
Dong Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1621208

Original Research

Accepted on 30 Jun 2025

Co-Delivery of Anti-inflammatory and Antioxidant Agents via Polymersomes for Osteoarthritis Therapy

in Experimental Pharmacology and Drug Discovery

Mengjie Rui
Li Wang
Ke Mi
Yinfeng Li
Naying Fang
Yingying Ge
Qiuqi Feng
Yaqi Luo
Chunlai Feng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1635761

Review

Accepted on 30 Jun 2025

Pharmacological effects, molecular mechanisms and strategies to improve bioavailability of curcumin in the treatment of neurodegenerative diseases

in Ethnopharmacology

Gang Wang
Xueyuan Zhou
Xiaoyan Pang
Ke Ma
Lu Li
Yuexin Song
Dongxia Hou
Xiaohua Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1625821