Frontiers in Pharmacology

Review

Published on 08 Jan 2026

Ethnopharmacological insights into uterine fibroids: a review of etiology, and therapeutic potential of natural products

in Ethnopharmacology

Gcobisa Valencia Manzane
Joe Sekomeng Modise
Bamide Joseph Okoli
Fanyana Mtunzi
Mzimkhulu Ephraim Monapathi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1714256

1,155 views

Original Research

Published on 08 Jan 2026

A significant gap between inadequate pharmacotherapy and substantial unmet needs in palmar hyperhidrosis management in China: insights from a questionnaire-based survey among outpatients

in Ethnopharmacology

Ning Pang
Yi Liu
Chaoqun Ma
Yingkun Liu
Lin Huang
Xiaohong Zhang
Yanguo Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1715189

1,411 views

Original Research

Published on 08 Jan 2026

Drug-induced peripheral nerve palsy: a real-world study based on FAERS data from 2004 to the third quarter of 2024

in Pharmacoepidemiology

Yingjie Li
Xueliang Yi
Nengwei Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1691263

754 views

Mini Review

Published on 08 Jan 2026

ITGA4 genetic variants as a predictor of therapeutic responsivity to autoimmune diseases

in Pharmacogenetics and Pharmacogenomics

Matheus D. De Matos
Bárbara D. Guimenes
Giovanni K. Pavani
Gabriel Gripp Fernandes
Guilherme C. Montes
Fabrícia L. Fontes-Dantas

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1745315

773 views

Original Research

Published on 08 Jan 2026

Cardamonin induces apoptosis of colorectal cancer cells via targeted inhibition of the JAK/STAT3/epithelial-mesenchymal transition (EMT) signaling axis

in Pharmacology of Anti-Cancer Drugs

Min Wu
Chuan Chen
Dan Ren
Zuo Du
Zhenzhong Liu
Wenhu Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1739201

739 views

Review

Published on 08 Jan 2026

Traditional Chinese medicine for HIV-related chronic comorbidities: evidence and potential therapeutic mechanisms

in Ethnopharmacology

Jiahe Li
Liran Xu
Xue Ding
Xiuxia Ma
Pengyu Qian
Nao Qiu
Jingyu Yue

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1698434

896 views

Original Research

Published on 08 Jan 2026

Pharmacological characterization and preclinical evaluation of 11h: a novel, brain-penetrant PDE4 inhibitor for neurological disorders

in Experimental Pharmacology and Drug Discovery

Jacob Lackovic
Sougata Dey
Sara Jane Ward
Nigel H. Greig
David Tweedie
Nassim Beiranvand
Uksha Saini
Dev Chatterjee
Atul Varadhachary

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1720327

1,131 views

Original Research

Published on 08 Jan 2026

Berberine suppresses hepatocellular carcinoma progression by blocking IL-4-JAK1-STAT6-mediated M2 polarization of macrophage

in Pharmacology of Anti-Cancer Drugs

Peng Wang
Yuwen Zhong
Mengkai Li
Qing Liang
Weiyi Jiang
Mengqi Zhuang
Xuecheng Ge
Huixing Li
Yaoshuai Zhang
Yu Qiao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1734201

1,079 views

Original Research

Published on 08 Jan 2026

Erythrosine-induced hepatic biomarkers and histopathological changes in male rats: protective effects of lycopene and anthocyanin

in Gastrointestinal and Hepatic Pharmacology

Safa H. Qahl
Fatimah A. Alqahtani
Haleema Al-Nahari
Fawzyah A. Alghamdi
Fatimah H. Khouja
Amna H. Khouja

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1718792

541 views

Original Research

Published on 08 Jan 2026

Multimodal data-driven predictive model for vancomycin serum concentrations in postoperative cardiac surgery patients under cardiopulmonary bypass: a single-center retrospective study

in Drug Metabolism and Transport

Pengqiang Du
Wenjin Zhang
Yujie Zhou
Taoran Li
Xinlei Qi
Wei Si
Aifeng Wang
Yongcheng Ma
Xingang Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1707557

522 views

Original Research

Published on 08 Jan 2026

Adherence to denosumab therapy and all-cause mortality in dialysis patients with osteoporosis: a retrospective cohort exploratory study

in Drugs Outcomes Research and Policies

Ying-Chou Chen
Jia-Feng Chen
Shan-Fu Yu
Chung-Yuan Hsu
Chien-Hua Chiu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1708051

899 views

Original Research

Published on 08 Jan 2026

Quantifying structural selection bias in observational cohort data: a ponderation analysis of age - specific incidence rates to inform vaccine safety verification

in Drugs Outcomes Research and Policies

Marco Roccetti

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1754809

706 views

Review

Accepted on 07 Jan 2026

Comprehensive Review of Tujia "Lian" Medicinal Botanical Drugs: Traditional Classification System, Phytochemical, and Pharmacological Profile

in Ethnopharmacology

Nan Kuang
Yu Mao
Muhammad Aamer
Piaopiao Jiang
Feibing Huang
Yupei Yang
Wenbing Sheng
Caiyun Peng
Wei Wang
Bin Li

Frontiers in Pharmacology

176 views

Original Research

Accepted on 07 Jan 2026

Evaluating a Multifaceted Stewardship Intervention on Proton Pump Inhibitor Utilization: An Interrupted Time Series Analysis of Prescribing Patterns in a Northwest Chinese Hospital

in Drugs Outcomes Research and Policies

Xiaoling Wang
David McIver
Hui Min
Jia Guo
Haiyan Li

Frontiers in Pharmacology

159 views

Original Research

Published on 07 Jan 2026

Data mining historical Chinese medical recipe collections and nuclear receptor profiling identify plant fractions that modulate glucocorticoid receptor activity

in Ethnopharmacology

Joachim Prackwieser
René Houtman
Tim Kievits
Diana Melchers
Haifeng Guan
Georg Seifert
Frank Konietschke
Kai Lamottke
Paul U. Unschuld
Nalini Kirk

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1681729

958 views

Editorial

Published on 07 Jan 2026

Editorial: Novel therapeutics for urological cancers

in Pharmacology of Anti-Cancer Drugs

Shuai Tang
Benyi Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1771902

663 views

Original Research

Published on 07 Jan 2026

Prediction of prognosis and immunotherapy response of tryptophan metabolism genes in acute myeloid leukemia

in Pharmacology of Anti-Cancer Drugs

Tantan Zhong
Meirui Zhang
Xinran Qi
Zhihui Qi
Peipei Li
Na Wang
Xianghua Wang
Panpan Feng
Xiaosheng Fang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1714246

841 views

Original Research

Published on 07 Jan 2026

Hyperoside ameliorates lupus nephritis by suppressing AKT1-mediated PANoptosis in podocytes: integrating network pharmacology and experimental validation

in Renal Pharmacology

Lili Cheng
Zhongfu Tang
Ming Li
Chuanbing Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1726254

1,113 views

Methods

Published on 07 Jan 2026

Venetoclax concentration affects the incidence of haematological adverse events in patients with acute myeloid leukaemia

in Drug Metabolism and Transport

Jing Chen
Xi Yang
Jingxian Xie
Lijuan Zhang
Lu Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1710282

815 views

Correction

Published on 07 Jan 2026

Correction: Hesperetin prevents bone resorption by inhibiting RANKL-induced osteoclastogenesis and Jnk mediated Irf-3/c-Jun activation

in Translational Pharmacology

Qiang Zhang
Xinqiao Tang
Zhong Liu
Xiaoxia Song
Dan Peng
Wei Zhu
Zhengxiao Ouyang
Wanchun Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1678215

403 views

Systematic Review

Published on 07 Jan 2026

Subcutaneous versus intravenous trastuzumab for HER2-positive breast cancer: a global systematic review and meta-analysis with a cost-minimization analysis from the Chinese healthcare system perspective

in Drugs Outcomes Research and Policies

Zheng Zeng
Li Zhong
Ling Zhu
Luqin Liao
Zefeng Zhu
Yuening Cao
Da Zheng
Guidong Huang
Wei Chen
Lin Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1730175

962 views

Review

Published on 07 Jan 2026

Advances in pulmonary neuroendocrine cells and their cellular interactions in asthma pathogenesis

in Inflammation Pharmacology

Lanlan Wang
Hui Wang
Yamei Yuan
Weidong Ye
Xiangming Fang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1725531

729 views

Original Research

Published on 07 Jan 2026

Refined target-mediated drug disposition modeling of the anti-tissue factor pathway inhibitor antibody MG1113 in cynomolgus monkeys and rabbits

in Translational Pharmacology

Heechun Kwak
Yoo-Seong Jeong
Jiyoung Kim
Minsoo Lee
Seonyoung Byoun
Yasunori Aoki
Suk-Jae Chung
Wooin Lee

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1745702

909 views

Original Research

Published on 07 Jan 2026

Hypericin alleviates cerebral ischemia/reperfusion injury by modulating endoplasmic reticulum stress

in Experimental Pharmacology and Drug Discovery

Tingting Li
Chao Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1723495

819 views

29,455 articles

articles

Ethnopharmacological insights into uterine fibroids: a review of etiology, and therapeutic potential of natural products

A significant gap between inadequate pharmacotherapy and substantial unmet needs in palmar hyperhidrosis management in China: insights from a questionnaire-based survey among outpatients

Drug-induced peripheral nerve palsy: a real-world study based on FAERS data from 2004 to the third quarter of 2024

ITGA4 genetic variants as a predictor of therapeutic responsivity to autoimmune diseases

Cardamonin induces apoptosis of colorectal cancer cells via targeted inhibition of the JAK/STAT3/epithelial-mesenchymal transition (EMT) signaling axis

Traditional Chinese medicine for HIV-related chronic comorbidities: evidence and potential therapeutic mechanisms

Pharmacological characterization and preclinical evaluation of 11h: a novel, brain-penetrant PDE4 inhibitor for neurological disorders

Berberine suppresses hepatocellular carcinoma progression by blocking IL-4-JAK1-STAT6-mediated M2 polarization of macrophage

Erythrosine-induced hepatic biomarkers and histopathological changes in male rats: protective effects of lycopene and anthocyanin

Multimodal data-driven predictive model for vancomycin serum concentrations in postoperative cardiac surgery patients under cardiopulmonary bypass: a single-center retrospective study

Adherence to denosumab therapy and all-cause mortality in dialysis patients with osteoporosis: a retrospective cohort exploratory study

Quantifying structural selection bias in observational cohort data: a ponderation analysis of age - specific incidence rates to inform vaccine safety verification

Comprehensive Review of Tujia "Lian" Medicinal Botanical Drugs: Traditional Classification System, Phytochemical, and Pharmacological Profile

Evaluating a Multifaceted Stewardship Intervention on Proton Pump Inhibitor Utilization: An Interrupted Time Series Analysis of Prescribing Patterns in a Northwest Chinese Hospital

Data mining historical Chinese medical recipe collections and nuclear receptor profiling identify plant fractions that modulate glucocorticoid receptor activity

Editorial: Novel therapeutics for urological cancers

Prediction of prognosis and immunotherapy response of tryptophan metabolism genes in acute myeloid leukemia

Hyperoside ameliorates lupus nephritis by suppressing AKT1-mediated PANoptosis in podocytes: integrating network pharmacology and experimental validation

Venetoclax concentration affects the incidence of haematological adverse events in patients with acute myeloid leukaemia

Correction: Hesperetin prevents bone resorption by inhibiting RANKL-induced osteoclastogenesis and Jnk mediated Irf-3/c-Jun activation

Subcutaneous versus intravenous trastuzumab for HER2-positive breast cancer: a global systematic review and meta-analysis with a cost-minimization analysis from the Chinese healthcare system perspective

Advances in pulmonary neuroendocrine cells and their cellular interactions in asthma pathogenesis

Refined target-mediated drug disposition modeling of the anti-tissue factor pathway inhibitor antibody MG1113 in cynomolgus monkeys and rabbits

Hypericin alleviates cerebral ischemia/reperfusion injury by modulating endoplasmic reticulum stress