Frontiers in Pharmacology

Systematic Review

Published on 07 Jan 2026

Subcutaneous versus intravenous trastuzumab for HER2-positive breast cancer: a global systematic review and meta-analysis with a cost-minimization analysis from the Chinese healthcare system perspective

in Drugs Outcomes Research and Policies

Zheng Zeng
Li Zhong
Ling Zhu
Luqin Liao
Zefeng Zhu
Yuening Cao
Da Zheng
Guidong Huang
Wei Chen
Lin Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1730175

966 views

Original Research

Published on 07 Jan 2026

Pharmacovigilance insights: safety profiles of antifungal agents for invasive aspergillosis

in Pharmacoepidemiology

Wei Jia
Tiezhou Wang
Jingru Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1718019

792 views

Original Research

Published on 07 Jan 2026

Mitochondrial dysfunction and apoptotic signaling induced by the combined action of 2-aminoethyl dihydrogen phosphate and methyl-β-cyclodextrin in melanoma cells

in Pharmacology of Anti-Cancer Drugs

Thalles Anthony Duarte de Oliveira
Ranya Sthephanie Nascimento Ribeiro
Rosa Andrea Nogueira Laiso
Monique Gonçalves Alves
Yasmim Emilly Moreira Sousa
Ícaro Gabriel Teles Pacheco de Matos
Daniel da Conceição Rabelo
Rose Eli Grassi Rici
Sergio Mestieri Chammas
Solange Castro Afeche

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1753894

847 views

Original Research

Published on 07 Jan 2026

Cerebrolysin, hemorrhagic transformation, and anticoagulation timing after reperfusion therapy in stroke: post hoc secondary analysis of the CEREHETIS trial

in Neuropharmacology

Mikhail N. Kalinin
Dina R. Khasanova

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1725255

1,711 views

Original Research

Published on 07 Jan 2026

Association between vancomycin therapeutic drug monitoring and improved clinical outcomes in critically ill patients receiving renal replacement therapy: a retrospective cohort study

in Drugs Outcomes Research and Policies

Huaidong Peng
Xiaomei Tang
Lijin Chen
Qilin Yang
Jinliang Cai
Tingting Xie
Dan Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1715023

869 views

Original Research

Published on 07 Jan 2026

DDI-AttendNet: cross attention with structured graph learning for inter-drug connectivity analysis

in Experimental Pharmacology and Drug Discovery

Jing Wang
Huili Du
Yuanlei Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1680655

431 views

Review

Published on 07 Jan 2026

κ-opioid receptor: from analgesic target to neuroimmune hub

in Inflammation Pharmacology

Qinsi Tan
Mengjin Zheng
Huaixin Xing

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1744231

1,019 views

Original Research

Published on 07 Jan 2026

Medication use in Poland for children and adolescents with neurodevelopmental disorders: before, during and after the COVID-19 pandemic - a retrospective pharmacoepidemiological study using national reimbursement data

in Pharmacoepidemiology

Andrzej Silczuk
Malwina Hołownia-Voloskova
Anna Mosiołek
Otton Roubinek
Katarzyna Bliźniewska-Kowalska
Krzysztof Marcin Zakrzewski
Marcin Czech

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1728388

939 views

Review

Published on 07 Jan 2026

The improvement effect and mechanism of traditional Chinese medicine on chemotherapy-induced diarrhea: a systematic review

in Ethnopharmacology

Yuzheng Wu
Xiaoyan Cao
Lequan Yu
Jingchun Yao
Chenghong Sun
Jingya Ruan
Dan Wang
Yi Zhang
Tao Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1648107

981 views

Review

Published on 07 Jan 2026

Pharmacological and bioactive properties of Artemisia argyi H. Lév. & Vaniot essential oil: a review

in Ethnopharmacology

Qing Gao
Yanqin Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1664658

1,091 views

Case Report

Published on 07 Jan 2026

Case Report: Perioperative application of trastuzumab deruxtecan in HER2 exon 20 mutation-positive non-small cell lung cancer

in Pharmacology of Anti-Cancer Drugs

Wenzhu Li
Zhenzhen Xiao
Jiaqi Yang
Lirong Liu
Xiaoshu Chai
Haibo Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1629854

786 views

Review

Published on 07 Jan 2026

Roxadustat for renal anemia: current clinical experience

in Renal Pharmacology

Jialing Ji
Zhongtang Li
Shuping Fang
Zuolin Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1712869

1,263 views

Original Research

Published on 07 Jan 2026

Comparative safety profiles of spironolactone, eplerenone, and finerenone: a pharmacovigilance study based on FAERS data from 2004 to 2024

in Pharmacoepidemiology

Kaiyun Ji
Xingjun Huang
Fang Wang
Lei Zhang
Yifan Zheng
Ligang Ji
Ying Ju
Xiaodong Zhuang
Jia Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1702257

1,434 views

Systematic Review

Published on 07 Jan 2026

Neuroprotective effects of traditional Chinese medicine formulas in animal models of retinal degenerative diseases: a systematic review and meta-analysis

in Ethnopharmacology

Yunxi Xu
Qindong Mi
Qi Yong
Chao Xu
Dingmeng Zhao
Chuning Wang
Zhongshan Jiang
Chenghao Yu
Hejiang Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1695150

1,063 views

Original Research

Published on 07 Jan 2026

Steaming duration-dependent effects on the in vivo distribution, anti-fatigue activity, and gut microbiota modulation of Polygonatum cyrtonema Hua polysaccharides

in Ethnopharmacology

Shengrong Lin
Yanling Wang
Weijing Wu
Jiaqi Huang
Xinqi Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1721319

677 views

Correction

Published on 07 Jan 2026

Correction: Licochalcone D reduces H2O2-induced SH-SY5Y cell neurotoxicity by regulating reactive oxygen species

in Ethnopharmacology

Ah-Won Kwak
Seungmin Park
Ha-Na Oh
Jung-Hyun Shim
Goo Yoon
Woo-Keun Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1721860

588 views

Clinical Trial

Published on 07 Jan 2026

Dezocine and butorphanol for the prevention of sufentanil-induced cough: a randomized controlled trial investigating the impact of intravenous access site

in Respiratory Pharmacology

Ying Liu
Hong-Yan Ma
Jing-Hui Shi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1690090

589 views

Review

Published on 07 Jan 2026

Targeting the AMP-activated protein kinase pathway: the active metabolites of botanical drugs represent potential strategies for treating metabolic-associated fatty liver disease

in Ethnopharmacology

Qi Liang
Li Ai
Lin He
Liang-Chen Wang
Jiao-Long Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1681880

839 views

Review

Accepted on 06 Jan 2026

Efficacy and Safety of Aflibercept Biosimilars Compared to Aflibercept in the Treatment of Neovascular Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis

in Drug Metabolism and Transport

CHEN LIU
Yating Zhou
Zixun Wang
Zongyue Zhan

Frontiers in Pharmacology

277 views

Review

Published on 06 Jan 2026

Policy and legal perspectives on the traditional Chinese medicine varietal protection system (TCMVPS): reform or abolition?

in Ethnopharmacology

Yanhui Wang
Ke Sun
Dong Hua

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1724528

1,121 views

Review

Published on 06 Jan 2026

Advancements in research on the cardiovascular toxicity caused by TEC family kinases inhibitors

in Cardiovascular and Smooth Muscle Pharmacology

Yi Zhang
Huangxi Fu
Xingchen Kang
Zixuan Qiu
Hao Yan
Qiaojun He
Bo Yang
Zhifei Xu
Peihua Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1726458

982 views

Original Research

Published on 06 Jan 2026

Preventive effect of small molecule active substances on septic cardiomyopathy after abdominal trauma: a systematic review and meta-analysis

in Cardiovascular and Smooth Muscle Pharmacology

Gen Ouyang
Neng Wang
Yujuan Liu
Chuang Yang
Peng Zeng
Tao Gong
Lu Tao
Ying Zheng
Guiying Ye
Hong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1665372

548 views

Review

Published on 06 Jan 2026

SIRT1: The first key to unlocking the mystery of cardiovascular diseases

in Cardiovascular and Smooth Muscle Pharmacology

Khuzin Dinislam
Muneer Ahmed Khoso
Valeriy A. Kataev
Svetlana Meshcheryakova
Heng Liu
Ling Liu
Madi Guo
Song Wang
Han Lou
Yong Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1668718

1,337 views

Systematic Review

Published on 06 Jan 2026

A meta-analysis of the traditional herb Zicao and its active components for atopic dermatitis

in Ethnopharmacology

Qin-yao Wu
Ya-yi Jiang
Jun-e Ming
Ping-sheng Hao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1648894

1,144 views

29,455 articles

articles

Subcutaneous versus intravenous trastuzumab for HER2-positive breast cancer: a global systematic review and meta-analysis with a cost-minimization analysis from the Chinese healthcare system perspective

Pharmacovigilance insights: safety profiles of antifungal agents for invasive aspergillosis

Mitochondrial dysfunction and apoptotic signaling induced by the combined action of 2-aminoethyl dihydrogen phosphate and methyl-β-cyclodextrin in melanoma cells

Cerebrolysin, hemorrhagic transformation, and anticoagulation timing after reperfusion therapy in stroke: post hoc secondary analysis of the CEREHETIS trial

Association between vancomycin therapeutic drug monitoring and improved clinical outcomes in critically ill patients receiving renal replacement therapy: a retrospective cohort study

DDI-AttendNet: cross attention with structured graph learning for inter-drug connectivity analysis

κ-opioid receptor: from analgesic target to neuroimmune hub

Medication use in Poland for children and adolescents with neurodevelopmental disorders: before, during and after the COVID-19 pandemic - a retrospective pharmacoepidemiological study using national reimbursement data

The improvement effect and mechanism of traditional Chinese medicine on chemotherapy-induced diarrhea: a systematic review

Pharmacological and bioactive properties of Artemisia argyi H. Lév. & Vaniot essential oil: a review

Case Report: Perioperative application of trastuzumab deruxtecan in HER2 exon 20 mutation-positive non-small cell lung cancer

Roxadustat for renal anemia: current clinical experience

Comparative safety profiles of spironolactone, eplerenone, and finerenone: a pharmacovigilance study based on FAERS data from 2004 to 2024

Neuroprotective effects of traditional Chinese medicine formulas in animal models of retinal degenerative diseases: a systematic review and meta-analysis

Steaming duration-dependent effects on the in vivo distribution, anti-fatigue activity, and gut microbiota modulation of Polygonatum cyrtonema Hua polysaccharides

Correction: Licochalcone D reduces H2O2-induced SH-SY5Y cell neurotoxicity by regulating reactive oxygen species

Dezocine and butorphanol for the prevention of sufentanil-induced cough: a randomized controlled trial investigating the impact of intravenous access site

Targeting the AMP-activated protein kinase pathway: the active metabolites of botanical drugs represent potential strategies for treating metabolic-associated fatty liver disease

Efficacy and Safety of Aflibercept Biosimilars Compared to Aflibercept in the Treatment of Neovascular Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis

Policy and legal perspectives on the traditional Chinese medicine varietal protection system (TCMVPS): reform or abolition?

Advancements in research on the cardiovascular toxicity caused by TEC family kinases inhibitors

Preventive effect of small molecule active substances on septic cardiomyopathy after abdominal trauma: a systematic review and meta-analysis

SIRT1: The first key to unlocking the mystery of cardiovascular diseases

A meta-analysis of the traditional herb Zicao and its active components for atopic dermatitis