Frontiers in Pharmacology

Correction

Published on 11 Dec 2025

Correction: Cimifugin suppresses NF-κB signaling to prevent osteoclastogenesis and periprosthetic osteolysis

in Translational Pharmacology

Juan Duan
Xuantao Hu
Tao Li
Gen Wu
Pengcheng Dou
Zhengxiao Ouyang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1678203

537 views

Original Research

Published on 11 Dec 2025

Efficacy and safety of Jinhuang ointment in treating acute gouty arthritis: a retrospective cohort study

in Experimental Pharmacology and Drug Discovery

Honglin Wang
Huiling Mei
Yuyu Duan
Wei Hua
Aoshuang Xu
Lin Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1728414

1,224 views

Review

Published on 11 Dec 2025

Pharmacological mechanisms of traditional Chinese medicine metabolites in regulating Treg cells: an integrative pathway review

in Ethnopharmacology

Chao Wang
Ming-Jie Liao
Yao Wu
Heng Lin
Zhen-Zhong Ye
Wen-Zhe Ma
Qing Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1527421

1,551 views

Original Research

Published on 11 Dec 2025

Fraxin modulates lipid metabolism as well as gut flora to avert NAFLD

in Gastrointestinal and Hepatic Pharmacology

Yang Jing
Dong Huicong
Guo Xuanchi
Li Cao
Zhang Huanhuan
Guo Yongze

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657966

1,435 views

Original Research

Published on 11 Dec 2025

Safety evaluation and toxicokinetics of repeated inhalation exposure to pegylated interferon α-2b

in Drug Metabolism and Transport

Cuifang Ji
Xunlian Ji
Huan Li
Qinfang Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1689087

725 views

Systematic Review

Published on 10 Dec 2025

From mechanisms to anti-fibrotic drugs in hepatic stellate cell research: a global bibliometric analysis with patent and clinical perspectives (2000–2025)

in Gastrointestinal and Hepatic Pharmacology

Xiaowen Mao
Peng Chen
Palidan Wubur
Yi Liu
Yuan Zhao
Siwei Zhang
Na Guan
Bin Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1734449

2,139 views

Original Research

Published on 10 Dec 2025

Real-world patient outcomes with Blinatumomab and Inotuzumab in adult relapsed/refractory B-cell acute lymphoblastic leukemia: a retrospective analysis from two Romanian oncology centers

in Translational Pharmacology

Ion Antohe
Amalia Titieanu
Vlad Andrei Cianga
Cosmin Minciună
Cătălin Dănăilă
Alina Daniela Tănase
Iuliu Ivanov
Loredana Dragoş
Mihaela Zlei
Mihaela Mențel

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1684382

1,268 views

Original Research

Published on 10 Dec 2025

Isoliensinine confers neuroprotection and alleviates LPS-induced neuroinflammation in microglia by regulating the MAPK/NF-κB signaling

in Inflammation Pharmacology

Mengqin Yuan
Jinda Hu
Lichen Gao
Wei Long
Sirui Wang
Xinyue Tan
Jinyue Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1675865

1,167 views

Systematic Review

Published on 10 Dec 2025

Traditional Chinese medicine for non-alcoholic fatty liver disease: an overview of systematic reviews with evidence mapping and metabolic outcome assessment

in Ethnopharmacology

Juanjuan Li
Ruimin Jiao
Wenquan Su
Wei Chen
Xiangyu Hu
Shuai Xu
Lie Xu
Weiwei Yao
Kejia Liu
Hong You

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1675793

2,077 views

Original Research

Published on 10 Dec 2025

Real-world data analysis of the risk of Fournier’s gangrene in patients using sodium-glucose cotransporter 2 inhibitors (SGLT2i)

in Translational Pharmacology

Moritz Hertel
Hanno Jaoulak
Max Heiland
Susanne Nahles
Robert Preissner
Saskia Preissner

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1643866

1,004 views

Review

Published on 10 Dec 2025

Biological effects of human placental extracts - variations in manufacturing methods and compositions

in Ethnopharmacology

Yikelamu Alimu
Takeshi Yamamoto
Yasukazu Nakahata

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1707890

2,321 views

Original Research

Published on 10 Dec 2025

Off-target autophagy disruption associated with a novel liver toxicity in dogs for a highly basic heterobifunctional protein degrader

in Predictive Toxicology

James E. Kath
Rebecca Kohnken
Timothy Brayman
Junhai Yang
Katharina Haag
Jingyi Gong
Christopher Untucht
Christiane Imhof
Kenneth P. Robinson
Ryan A. McClure

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1664889

1,952 views

Original Research

Published on 10 Dec 2025

Serum metabolomics identifies novel prognostic biomarkers in amanita poisoning

in Drug Metabolism and Transport

Dan Zhu
Jie Zhong
Yarong Liu
Sicheng Zhang
Lianhong Zou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1716911

1,130 views

Original Research

Published on 10 Dec 2025

Lentinan inhibits colorectal cancer stemness by binding CD133 and suppressing the CD133/p85/p-AKT signaling axis

in Pharmacology of Anti-Cancer Drugs

Yan Liu
Lufei Yang
Junxi Liu
Zihao He
Jingyi Wang
Yu Zhang
Kaiping Wang
Jinglin Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1725716

1,069 views

Review

Published on 10 Dec 2025

Flow cytometric detection of leukemic stem cells in Acute Myeloid Leukemia: current status and future directions

in Pharmacology of Anti-Cancer Drugs

Mariam M. Youssef
Christopher Y. Park

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1724473

1,772 views

Review

Published on 10 Dec 2025

Selected traditional Chinese medicine interventions for post-stroke cerebral edema: a review integrating clinical evidence and mechanistic insights

in Ethnopharmacology

Junyue Huang
Yujia Jin
Yuping Chen
Mengsi Wang
Jian Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1709821

1,231 views

Review

Published on 10 Dec 2025

Therapeutic potential of Abelmoschus manihot: mechanisms of action and clinical use in traditional Chinese medicine formulas

in Ethnopharmacology

Chu Xue
Haitao Ge
Yaru Liu
Yan Zhao
Wenjie Huang
Zhaowen Lu
Qiuhui Ye
Xiaoli Chen
Zhengyu Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1709530

851 views

Review

Published on 10 Dec 2025

Immune modulation in inflammatory bowel disease: therapeutic promise of baicalein

in Inflammation Pharmacology

Yang Wang
Luyao Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1723606

1,510 views

Original Research

Published on 10 Dec 2025

Potential lipid-lowering effects of preussin B on inhibition of intestinal cholesterol absorption: integrative mechanisms of action and proteomic analysis

in Experimental Pharmacology and Drug Discovery

Atcharaporn Ontawong
Jakkapong Inchai
Pannita Holasut
Wararat Chiangjong
Thaweesak Chieochansin
Davide Crucitti
Adrián Mosquera Orgueira
Worarat Rojanaverawong
Thanthakan Saithong
Kornwalai Tunkaew

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1708213

1,080 views

Original Research

Published on 10 Dec 2025

Optimisation of peptides targeting reverse transcriptase HIV-1 using QSAR, machine learning, and computational approaches

in Experimental Pharmacology and Drug Discovery

Fachrur Rizal Mahendra
Indira Prakoso
Alfa Marzelino
Muhamad Rizqy Fadhillah
Syukriyansyah
Muhammad Marsha Azzami Hasibuan
Juniza Firdha Suparningtyas
Mikael Kristiadi
Aprijal Ghiyas Setiawan
Faris Izzatur Rahman

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1707377

2,089 views

Review

Published on 09 Dec 2025

Pharmacological effects and application prospects of mussel adhesive proteins

in Translational Pharmacology

Junsha An
Zengmiao Hou
Jiaqi Li
Qian Bi
Shile Huang
Cheng Peng
Fu Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1704475

1,621 views
1 citation

Original Research

Published on 09 Dec 2025

Protective effects of an Fc-engineered PD-L1 fusion protein in a spontaneous abortion model and a Th17 cell–induced pregnancy loss model

in Experimental Pharmacology and Drug Discovery

Guangyao Li
Tiantian Wang
Dan Tan
Yamin Jin
Xuemei Zhou
Hongru Ai
Xinya Zheng
Xiaochen Ren
Shi Hu
Changhai Lei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1703805

752 views

Original Research

Published on 09 Dec 2025

Pharmacokinetics and pharmacodynamics of cannabigerol (CBG) in the C57BL/6Crl mouse

in Experimental Pharmacology and Drug Discovery

Ayat Zagzoog
Kenzie Halter
Nini Ha
Alayna M. Jones
Rachel Andres
Andy Kim
Deborah Michel
Jane Alcorn
Robert B. Laprairie

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1672098

1,880 views

Editorial

Published on 09 Dec 2025

Editorial: Innovative approaches for wound treatment

in Integrative and Regenerative Pharmacology

Junxiao Zhang
Shenglin Geng
Guojuan Fan
Jinlong Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1738213

691 views

29,485 articles

articles

Correction: Cimifugin suppresses NF-κB signaling to prevent osteoclastogenesis and periprosthetic osteolysis

Efficacy and safety of Jinhuang ointment in treating acute gouty arthritis: a retrospective cohort study

Pharmacological mechanisms of traditional Chinese medicine metabolites in regulating Treg cells: an integrative pathway review

Fraxin modulates lipid metabolism as well as gut flora to avert NAFLD

Safety evaluation and toxicokinetics of repeated inhalation exposure to pegylated interferon α-2b

From mechanisms to anti-fibrotic drugs in hepatic stellate cell research: a global bibliometric analysis with patent and clinical perspectives (2000–2025)

Real-world patient outcomes with Blinatumomab and Inotuzumab in adult relapsed/refractory B-cell acute lymphoblastic leukemia: a retrospective analysis from two Romanian oncology centers

Isoliensinine confers neuroprotection and alleviates LPS-induced neuroinflammation in microglia by regulating the MAPK/NF-κB signaling

Traditional Chinese medicine for non-alcoholic fatty liver disease: an overview of systematic reviews with evidence mapping and metabolic outcome assessment

Real-world data analysis of the risk of Fournier’s gangrene in patients using sodium-glucose cotransporter 2 inhibitors (SGLT2i)

Biological effects of human placental extracts - variations in manufacturing methods and compositions

Off-target autophagy disruption associated with a novel liver toxicity in dogs for a highly basic heterobifunctional protein degrader

Serum metabolomics identifies novel prognostic biomarkers in amanita poisoning

Lentinan inhibits colorectal cancer stemness by binding CD133 and suppressing the CD133/p85/p-AKT signaling axis

Flow cytometric detection of leukemic stem cells in Acute Myeloid Leukemia: current status and future directions

Selected traditional Chinese medicine interventions for post-stroke cerebral edema: a review integrating clinical evidence and mechanistic insights

Therapeutic potential of Abelmoschus manihot: mechanisms of action and clinical use in traditional Chinese medicine formulas

Immune modulation in inflammatory bowel disease: therapeutic promise of baicalein

Potential lipid-lowering effects of preussin B on inhibition of intestinal cholesterol absorption: integrative mechanisms of action and proteomic analysis

Optimisation of peptides targeting reverse transcriptase HIV-1 using QSAR, machine learning, and computational approaches

Pharmacological effects and application prospects of mussel adhesive proteins

Protective effects of an Fc-engineered PD-L1 fusion protein in a spontaneous abortion model and a Th17 cell–induced pregnancy loss model

Pharmacokinetics and pharmacodynamics of cannabigerol (CBG) in the C57BL/6Crl mouse

Editorial: Innovative approaches for wound treatment