Frontiers in Pharmacology

Review

Published on 27 Nov 2025

Evaluation of natural products bioactivity in cardiovascular diseases utilizing zebrafish models: a comprehensive review

in Ethnopharmacology

Yiming Wang
Xiang Meng
Xuting Song
Lulu Wang
Xianghe Meng
Xiaoya Du
Ziyoviddin Yusupov
Komiljon Tojibaev
Yunpeng Wang
Min He

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1713417

1,151 views

Original Research

Published on 27 Nov 2025

Polyphenol-rich Morus nigra L. extract mitigates neuroinflammation and cognitive impairment through gut–brain axis modulation in an Alzheimer’s disease rat model

in Ethnopharmacology

Yue Li
Yangyi Zhang
Mengwen Liu
Tuerxunayi Dawuti
Xuanshi Chen
Hui Xiao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1695768

1,408 views

Systematic Review

Published on 27 Nov 2025

The efficacy and safety of combining different Chinese patent medicines with conventional Western drugs in the treatment of pediatric allergic rhinitis: network meta-analysis

in Obstetric and Pediatric Pharmacology

Yue Ma
Wenrui Huang
Hang Wu
Chunbo Zhang
Zhiyue Xiao
Yuying Gao
Junying Xie
Jingyao Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1693357

1,599 views

Original Research

Published on 27 Nov 2025

Gentamicin-loaded exosomes from IMMUNEPOTENT CRP enhance healing of infected diabetic wound in mice

in Integrative and Regenerative Pharmacology

Paola Leonor García Coronado
Brandon Alberto Garza Martínez
Kenia Arisbe Moreno Amador
David Reding Hernández
Diana G. Zárate Triviño
Diana Elia Caballero Hernández
Pablo Zapata Benavides
Gabriel Luna Barcenas
Cristina Rodríguez‐Padilla
Moisés Armides Franco Molina

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1682468

1,286 views

Review

Published on 27 Nov 2025

Echocardiographic assessment and new advances of right ventricle function in rats with pulmonary hypertension

in Cardiovascular and Smooth Muscle Pharmacology

Weijie Wang
Ming Ren
Dianxiang Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1682105

1,135 views

Mini Review

Published on 27 Nov 2025

The risk of developing more potent fentanyl analogs: a mini review

in Experimental Pharmacology and Drug Discovery

Benjamín Bustamante-Elgueta
Maikol D. Andrade
Cristóbal A. Quintul
Daniel A. Medina
Javier Campanini-Salinas

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1723733

1,972 views

Original Research

Published on 27 Nov 2025

Effectiveness of treatments to prevent femoral periprosthetic bone loss following total hip arthroplasty: a network meta-analysis

in Pharmacogenetics and Pharmacogenomics

Zhi-Hu Zhao
Tao Ling
Songqing Ye
Wei Luo
Jian-Xiong Ma
Xinlong Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1566890

1,432 views
1 citation

Original Research

Published on 27 Nov 2025

Disproportionality analysis of taste disorders using the FDA adverse event reporting system and Japanese adverse drug event report databases

in Pharmacoepidemiology

Yoji Kyotani
Kiichi Nakahira
Masanori Yoshizumi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1659746

1,367 views

Systematic Review

Published on 27 Nov 2025

The impact of SGLT2 inhibitors on cardiac remodeling after myocardial infarction: an updated meta-analysis of randomized controlled trials

in Experimental Pharmacology and Drug Discovery

Ma Li Xu
Hui Wang
Dan Ouyang
Hang Qi
Xin Hui Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1699066

1,812 views
1 citation

Review

Published on 27 Nov 2025

Regulatory mechanisms of luteolin in inflammatory respiratory diseases

in Respiratory Pharmacology

Peidao Sun
Xiangchen Chen
Yuhang Wang
Xiaolin Wang
Kejing Li
Hongbo Song
Jinlong Mao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1720824

2,397 views

Mini Review

Published on 27 Nov 2025

Small RNA or oligonucleotide drugs and challenges in evaluating drug-drug interactions

in Drug Metabolism and Transport

Joseph M. Cronin
Ai-Ming Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1720361

2,910 views

Original Research

Published on 27 Nov 2025

Photodynamic therapy with a novel photosensitizer inhibits BLM-induced pulmonary fibrosis in mice via MRC1-mediated pathway

in Experimental Pharmacology and Drug Discovery

Minghui Zhu
Nan Wang
Feiyu Zhang
Yumei Rong
Zhenyu Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1714450

1,173 views
1 citation

Original Research

Published on 27 Nov 2025

Xiaozhi Yufa decoction ameliorates androgenetic alopecia through inhibition of MAPK signaling and regulation of lipid metabolism

in Integrative and Regenerative Pharmacology

Yiyu Guo
Jie Wu
Yu Lu
Jianping Qin
Lanlan Huang
Fengrui Zhang
Xiaomei Zhou
Dengke Yang
Jianzhou Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1724224

1,327 views

Review

Accepted on 26 Nov 2025

The pharmacological effects and therapeutic potential of flavonoids in digestive diseases

in Gastrointestinal and Hepatic Pharmacology

Junkang Xu
Mengxuan Zhu
Xu Chen
Wenjing Chen
Jingyi Zhang
Cuizhe Liu
Lin Zhang

Frontiers in Pharmacology

203 views

Original Research

Published on 26 Nov 2025

Resveratrol attenuates pulmonary fibrosis by inhibiting alveolar epithelial senescence via targeting SASP-related proteins: an integrated bioinformatics-experimental study

in Experimental Pharmacology and Drug Discovery

Biao Zuo
Su Yuan
Chen Luo
Xu-Qin Du
Yong-Can Wu
Li-Peng Shi
Jin-Xin Chen
Bo-Tao Chen
Jie Zhou
Yi Ren

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1680998

2,887 views

Original Research

Published on 26 Nov 2025

Pentoxifylline vaginal gel improves sperm motility and vitality in asthenozoospermic males: A randomized, blinded, in vitro study

in Experimental Pharmacology and Drug Discovery

Cristina Trilla
Lidia Navarro
Mariona Rius
Juan José Espinós

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1669045

1,012 views

Review

Published on 26 Nov 2025

Bortezomib-induced peripheral neuropathy: from molecular mechanisms to clinical management

in Neuropharmacology

Yuting Yan
Yanqi Song
Quan Zhang
Lingwei Hu
Aidi Wang
Honglei Guo
Zhen Wang
Lin Ma
Baoshan Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1719384

1,958 views

Editorial

Published on 26 Nov 2025

Editorial: Mathematical modeling of medication nonadherence

in Drugs Outcomes Research and Policies

Sean D. Lawley
Teresa B. Gibson
Zheng Jiao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1741041

994 views

Correction

Published on 26 Nov 2025

Correction: Lack of the Nlrp3 inflammasome improves mice recovery following traumatic brain injury

in Neuropharmacology

Natasha Irrera
Gabriele Pizzino
Margherita Calò
Giovanni Pallio
Federica Mannino
Fausto Famà
Vincenzo Arcoraci
Vincenzo Fodale
Antonio David
Francesca Cosentino

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1733683

558 views

Review

Published on 26 Nov 2025

Celecoxib in oncology: targeting the COX-2/PGE2 axis to reprogram the tumor immune microenvironment and enhance multimodal therapy

in Pharmacology of Anti-Cancer Drugs

Boyang Kuang
Kuan Yang
Xiaoting Zhong
Yingwei Tan
Yi Zhou
Jianming Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1691392

2,074 views

Original Research

Published on 26 Nov 2025

Development and validation of a clinical prediction model for in-hospital mortality of severe pneumonia based on machine learning

in Respiratory Pharmacology

Kai Xie
Xiajin Huang
Zhen Li
Wenjing Yin
Xiaoxuan He
Xinyu Miao
Haifeng Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1660893

1,143 views

Original Research

Published on 26 Nov 2025

Identification, biotransformation, and neuroprotective potential of the ethanol extract of Alpiniae oxyphyllae fructus in neuroinflammation-related cognitive impairment

in Ethnopharmacology

Zirong Yi
Xinyu Wang
Lin Wang
Renfang Yin
Dongying Qi
Huan Liu
Yuxin Chen
Yamei Xie
Yuming Ma
Mengqi Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1714500

809 views

Mini Review

Published on 26 Nov 2025

Mini-review: The health benefits and applications of allicin

in Ethnopharmacology

Ke-Qian Chen
Hai-Bo Lei
Xiang Liu
Wen-Jing Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1715922

2,494 views

Original Research

Published on 26 Nov 2025

Estrogen associations with human pregnancy related increases in cytochrome P450 3A activity

in Drug Metabolism and Transport

Muluneh M. Fashe
Jonghwa Lee
Joseph T. Grieco
John K. Fallon
Ian R. Mulrenin
Megan N. Gower
Klarissa D. Jackson
Kim A. Boggess
Craig R. Lee

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1702419

1,137 views

29,505 articles

articles

Evaluation of natural products bioactivity in cardiovascular diseases utilizing zebrafish models: a comprehensive review

Polyphenol-rich Morus nigra L. extract mitigates neuroinflammation and cognitive impairment through gut–brain axis modulation in an Alzheimer’s disease rat model

The efficacy and safety of combining different Chinese patent medicines with conventional Western drugs in the treatment of pediatric allergic rhinitis: network meta-analysis

Gentamicin-loaded exosomes from IMMUNEPOTENT CRP enhance healing of infected diabetic wound in mice

Echocardiographic assessment and new advances of right ventricle function in rats with pulmonary hypertension

The risk of developing more potent fentanyl analogs: a mini review

Effectiveness of treatments to prevent femoral periprosthetic bone loss following total hip arthroplasty: a network meta-analysis

Disproportionality analysis of taste disorders using the FDA adverse event reporting system and Japanese adverse drug event report databases

The impact of SGLT2 inhibitors on cardiac remodeling after myocardial infarction: an updated meta-analysis of randomized controlled trials

Regulatory mechanisms of luteolin in inflammatory respiratory diseases

Small RNA or oligonucleotide drugs and challenges in evaluating drug-drug interactions

Photodynamic therapy with a novel photosensitizer inhibits BLM-induced pulmonary fibrosis in mice via MRC1-mediated pathway

Xiaozhi Yufa decoction ameliorates androgenetic alopecia through inhibition of MAPK signaling and regulation of lipid metabolism

The pharmacological effects and therapeutic potential of flavonoids in digestive diseases

Resveratrol attenuates pulmonary fibrosis by inhibiting alveolar epithelial senescence via targeting SASP-related proteins: an integrated bioinformatics-experimental study

Pentoxifylline vaginal gel improves sperm motility and vitality in asthenozoospermic males: A randomized, blinded, in vitro study

Bortezomib-induced peripheral neuropathy: from molecular mechanisms to clinical management

Editorial: Mathematical modeling of medication nonadherence

Correction: Lack of the Nlrp3 inflammasome improves mice recovery following traumatic brain injury

Celecoxib in oncology: targeting the COX-2/PGE2 axis to reprogram the tumor immune microenvironment and enhance multimodal therapy

Development and validation of a clinical prediction model for in-hospital mortality of severe pneumonia based on machine learning

Identification, biotransformation, and neuroprotective potential of the ethanol extract of Alpiniae oxyphyllae fructus in neuroinflammation-related cognitive impairment

Mini-review: The health benefits and applications of allicin

Estrogen associations with human pregnancy related increases in cytochrome P450 3A activity