Frontiers in Pharmacology

Specialty Grand Challenge

Published on 20 Nov 2025

Unifying pharmacology, systems biology, and regenerative medicine to advance personalized therapies

in Integrative and Regenerative Pharmacology

Albino Martins

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1729610

1,377 views

Original Research

Published on 20 Nov 2025

Evaluation of long-term safety profile of an EU-GMP certified Cannabis sativa L. strain in a naturally aging preclinical model

in Ethnopharmacology

Gabriela-Dumitrita Stanciu
Ivona Costachescu
Daniela-Carmen Ababei
Andrei Szilagyi
Raluca-Maria Gogu
Vlad-Constantin Craciun
Andrei-Daniel Timofte
Irina-Draga Caruntu
Cristina-Elena Dobre
Bogdan-Ionel Tamba

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1716366

1,114 views

Original Research

Published on 20 Nov 2025

Performance of AI-based machine learning models for overall survival prediction in advanced hepatocellular carcinoma patients receiving immunoradiotherapy

in Pharmacology of Anti-Cancer Drugs

Xiao Feng
Xiaonan Wang
Shengyuan Luo
Jianwei Zhou
Shanbao Ke

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1719479

1,241 views

Case Report

Published on 20 Nov 2025

Occupational 4-Methylsulfonyl-benzonitrile poisoning: a case report

in Predictive Toxicology

Jianjian Liu
Zhaozhao Shan
Yuru Liu
Yingying Zheng
Xiangdong Jian
Baotian Kan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1616964

858 views

Original Research

Published on 20 Nov 2025

Full-spectrum cannabis extracts for women with chronic pain syndromes: a real-life retrospective report of multi-symptomatic benefits after treatment with individually tailored dosage schemes

in Ethnopharmacology

Patrícia Montagner Soares Silva
Wesley Medeiros
Clarissa Nogueira Borges
Joaquim P. Brasil-Neto
Wilson Lessa Jr.
Ricardo Ferreira de Oliveira e Silva
Fabio V. Caixeta
Renato Malcher-Lopes

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1538518

3,211 views

Review

Published on 20 Nov 2025

Research progress on the use of polyphenols in the treatment of Crohn’s disease

in Gastrointestinal and Hepatic Pharmacology

Xianmei Zhong
Qian Dai
Jing Li
Jie Yang
Xi Zheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1704901

1,333 views

Original Research

Published on 20 Nov 2025

Receptor interaction profiles of 4-alkoxy-2,6-dimethoxyphenethylamines (Ψ derivatives) and related amphetamines

in Neuropharmacology

Karolina E. Kolaczynska
Daniel Trachsel
Marius C. Hoener
Matthias E. Liechti
Dino Luethi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1703480

2,906 views

Systematic Review

Published on 20 Nov 2025

Efficacy of pharmacological interventions and therapeutic exercises for rheumatoid arthritis: a systematic review and meta-analysis

in Inflammation Pharmacology

Timothy Adeyemi
Vitalis Ikenna Chukwuike
Motunrayo Adebukunola Oladimeji
Ufuoma Shalom Ahwinahwi
Victor Ayodeji Ayeni
Aisha Adam Abdullahi
Abdulmuminu Isah
Love Bukola Ayamolowo
Oluchukwu Perpetual Okeke
Olunike Abodunrin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1686128

1,990 views

Review

Published on 20 Nov 2025

Design and synthesis of natural antibacterial derivatives for ocular tuberculosis: a comprehensive review

in Pharmacology of Infectious Diseases

Isaiah Osei Duah
Gabriel Amankwah
Josephine Ampong
Sherlene Brown
Bernice Lebene Tettey
Hubert Osei Acheampong
Ruth Boahemaa Awuku
Cynthia Amaning Danquah

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1697986

1,644 views

Original Research

Published on 20 Nov 2025

Efficacy and safety of tacrolimus in the treatment of interstitial pneumonia with autoimmune features: a retrospective study

in Respiratory Pharmacology

Yanzao Zhao
Xuemei Huang
Xinyue Cao
Jie Luo
Xi He
Qianhui Yang
Anji Xiong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1721639

1,081 views

Systematic Review

Published on 20 Nov 2025

Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies

in Ethnopharmacology

Zeyi Lv
Zhuo Pan
Yue Huang
Hao Yang
Xinrong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1673712

2,671 views

Systematic Review

Published on 20 Nov 2025

Cardioprotective Chinese herbs and antiretroviral drug metabolism: a systematic review of in vitro evidence

in Ethnopharmacology

Wan-Jung Cheng
Anthony Jaworowski
Janine M. Trevillyan
Anna C. Hearps
Charlie C. Xue
Anthony L. Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1627058

1,295 views

Original Research

Published on 20 Nov 2025

Effects of Ophiopogon japonicus oligosaccharides on type 2 diabetes in rats via modulation of gut microbiota and metabolites

in Ethnopharmacology

Tingyu Yang
Baoting Chen
Jia Fang
Zilin Li
Yiming Liu
Aihua Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1710883

1,576 views

Systematic Review

Published on 20 Nov 2025

Therapeutic effect and safety of Wei-Fu-Chun in the treatment of chronic atrophic gastritis: a network meta-analysis

in Gastrointestinal and Hepatic Pharmacology

Yunbo Wu
Ling Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1693427

1,636 views
1 citation

Original Research

Published on 20 Nov 2025

Ivarmacitinib improves patient-reported outcomes across multiple domains in patients with active ankylosing spondylitis: a post hoc analysis of a phase II/III trial

in Inflammation Pharmacology

Xiaoyan Xu
Hua Wei
Linchen Liu
Rong Yang
Qing Shi
Dandan Pang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1710434

1,341 views

Systematic Review

Published on 20 Nov 2025

Comparative efficacy and safety of second-line therapies for patients with advanced hepatocellular carcinoma: a systematic review and network meta-analysis of randomized controlled trials

in Drugs Outcomes Research and Policies

Fengjiao Kang
Yin Wang
Fengqun Cai
Liuyun Wu
HuLin Wang
Lizhu Han
Qinan Yin
Lan Bai
Yuan Bian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1697949

1,701 views

Original Research

Published on 19 Nov 2025

Integrated metabolomics and gut microbiota analysis to explore the potential mechanism of levo-tetrahydropalmatine against ketamine addiction

in Neuropharmacology

Yan Du
Qing Ma
Xingcui Gao
Hongliang Su
Keming Yun
Li Du

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1698866

3,681 views

Original Research

Published on 19 Nov 2025

Ultrafine garlic powder alleviates non-alcoholic steatohepatitis by inhibiting hepatocyte ferroptosis and modulating ERK-dependent oxidative stress

in Experimental Pharmacology and Drug Discovery

Junhui Yu
Ningning Shao
Jianming Yang
Long Yang
Kaiwen Hong
Yuzhu Chen
Xiaoming Zhao
Hongzhi Yu
Tao Zhang
Jinrui Dong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1711917

1,842 views

Original Research

Published on 19 Nov 2025

Cost-utility analysis of PCSK9 inhibitors for hypercholesterolemia: a Chinese healthcare perspective

in Drugs Outcomes Research and Policies

Dandan Hu
Xu Deng
Mengwen Feng
Xinyue Zhang
Qingfeng He
Tao Wang
Zhen Feng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1708701

2,291 views

Systematic Review

Published on 19 Nov 2025

Different interventions in preventing sufentanil-induced cough: a systematic review and network meta-analysis

in Drugs Outcomes Research and Policies

Hao Liu
Yuewen He
Longfei Ding
Zhengze Zhang
Tong Wu
Ruogen Li
Yong Wang
Wuhua Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1619920

1,103 views

Systematic Review

Published on 19 Nov 2025

Qianyang Yuyin Granules for vascular damage in mild-to-moderate hypertensive patients: a systematic review with meta-analysis and trial sequential analysis

in Ethnopharmacology

Shidian Zhu
Qiannong Wu
Yanlin Liu
Fuming Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1612508

1,311 views

Review

Published on 19 Nov 2025

Artemisinin and its derivatives: all-rounders that may prevent the progression from lung injury to lung cancer

in Respiratory Pharmacology

Xin Xie
Qian Chen
Cui Guo
Jinhao Zeng
Qingying He

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1602581

4,581 views

Editorial

Published on 19 Nov 2025

Editorial: Organoids for drug discovery

in Experimental Pharmacology and Drug Discovery

Chongyang Shen
Mingliang You
Lingzhi Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1732060

789 views

Original Research

Published on 19 Nov 2025

Ultrasound-guided thoracic paravertebral block combined with dexmedetomidine improves perioperative analgesia and recovery in medical thoracoscopy: a randomized controlled trial

in Drugs Outcomes Research and Policies

Jia Nie
Wei Chen
Huanhuan Ma
Liang Fang
Zhimin Deng
Yu Zhang
Hai-Ying Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1684199

1,041 views

29,512 articles

articles

Unifying pharmacology, systems biology, and regenerative medicine to advance personalized therapies

Evaluation of long-term safety profile of an EU-GMP certified Cannabis sativa L. strain in a naturally aging preclinical model

Performance of AI-based machine learning models for overall survival prediction in advanced hepatocellular carcinoma patients receiving immunoradiotherapy

Occupational 4-Methylsulfonyl-benzonitrile poisoning: a case report

Full-spectrum cannabis extracts for women with chronic pain syndromes: a real-life retrospective report of multi-symptomatic benefits after treatment with individually tailored dosage schemes

Research progress on the use of polyphenols in the treatment of Crohn’s disease

Receptor interaction profiles of 4-alkoxy-2,6-dimethoxyphenethylamines (Ψ derivatives) and related amphetamines

Efficacy of pharmacological interventions and therapeutic exercises for rheumatoid arthritis: a systematic review and meta-analysis

Design and synthesis of natural antibacterial derivatives for ocular tuberculosis: a comprehensive review

Efficacy and safety of tacrolimus in the treatment of interstitial pneumonia with autoimmune features: a retrospective study

Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies

Cardioprotective Chinese herbs and antiretroviral drug metabolism: a systematic review of in vitro evidence

Effects of Ophiopogon japonicus oligosaccharides on type 2 diabetes in rats via modulation of gut microbiota and metabolites

Therapeutic effect and safety of Wei-Fu-Chun in the treatment of chronic atrophic gastritis: a network meta-analysis

Ivarmacitinib improves patient-reported outcomes across multiple domains in patients with active ankylosing spondylitis: a post hoc analysis of a phase II/III trial

Comparative efficacy and safety of second-line therapies for patients with advanced hepatocellular carcinoma: a systematic review and network meta-analysis of randomized controlled trials

Integrated metabolomics and gut microbiota analysis to explore the potential mechanism of levo-tetrahydropalmatine against ketamine addiction

Ultrafine garlic powder alleviates non-alcoholic steatohepatitis by inhibiting hepatocyte ferroptosis and modulating ERK-dependent oxidative stress

Cost-utility analysis of PCSK9 inhibitors for hypercholesterolemia: a Chinese healthcare perspective

Different interventions in preventing sufentanil-induced cough: a systematic review and network meta-analysis

Qianyang Yuyin Granules for vascular damage in mild-to-moderate hypertensive patients: a systematic review with meta-analysis and trial sequential analysis

Artemisinin and its derivatives: all-rounders that may prevent the progression from lung injury to lung cancer

Editorial: Organoids for drug discovery

Ultrasound-guided thoracic paravertebral block combined with dexmedetomidine improves perioperative analgesia and recovery in medical thoracoscopy: a randomized controlled trial