Frontiers in Pharmacology

Original Research

Published on 18 Nov 2025

Predicting tigecycline-related adverse events in infected patients: a machine learning approach with clinical interpretability

in Predictive Toxicology

Shiya Wu
Yuheng Chen
Wenjie Fan
Xirong Wu
Chaofeng Zhang
Yucang Lin
Qi Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1697929

1,399 views

Original Research

Published on 18 Nov 2025

Constructing an evaluation framework for primary pharmacovigilance systems in developing countries: a case study from China

in Pharmacoepidemiology

Shuang Lei
Shuzhi Lin
Xiaoying Zhu
Wei Liu
Qian Liu
Lin Yin
Bianling Feng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657574

1,001 views

Original Research

Published on 18 Nov 2025

Glial cell line-derived neurotrophic factor inhibits mast-cell-like RBL-2H3 cells activation via Ca2+-mediated degranulation and Ca2+/CaMKⅡ/JNK pathway

in Gastrointestinal and Hepatic Pharmacology

Wei Huang
Li Zeng
Li Zhang
Xinxing Zhang
Qin Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1697815

1,189 views

Review

Published on 18 Nov 2025

From bench to bedside, boswellic acids in anti-inflammatory therapy — mechanistic insights, bioavailability challenges, and optimization approaches

in Ethnopharmacology

Chuhang Peng
Yujia Yang
Yuzhi Wang
Bao Gong
Xiuting Sun
Xinquan Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1692443

3,719 views
1 citation

Original Research

Published on 18 Nov 2025

Curcumol alleviates endometriosis via correcting the aberrant activation of Fas/RIPK1-mediated PANoptosis

in Ethnopharmacology

Weiming Ni
Xiaoqin Wu
Li Feng
Min Xu
Yingzhou Tian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1691279

1,423 views

Review

Published on 18 Nov 2025

Substandard and falsified medicines in Africa: healthcare systems challenges, supply chain issues, regulatory challenges and strategies to increase access to quality medicines

in Drugs Outcomes Research and Policies

Billy Chabalenge
Tarsem Sahota
Irina Ermolina
Sangeeta Tanna

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1708784

2,491 views

Original Research

Published on 18 Nov 2025

In vivo pharmacokinetic evaluation of molnupiravir in patients with severe chronic kidney disease

in Renal Pharmacology

Yuanyuan Wang
Qiong Chen
Xuan Liu
Ling Zhang
Ming Chen
Shuowen Wang
Man Yang
Guorong Fan
Qiuling Fan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1696197

996 views

Original Research

Published on 18 Nov 2025

Impact of parathyroid Hormone’s dose, timing, and delivery mode on osteoclastogenesis and osteogenesis using a human periodontal ligament fibroblast model

in Experimental Pharmacology and Drug Discovery

Wael M. I. Talbi
Elizabeth Steemers
Jolanda M. A. Hogervorst
Ton Schoenmaker
Teun J. de Vries

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1661759

1,356 views

Review

Published on 18 Nov 2025

Comparison of short-term and long-term renal function effects of vasopressin and norepinephrine in patients with septic shock: a systematic review and meta-analysis

in Renal Pharmacology

Hongyu Wang
Xilin Liu
Hong Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1669636

1,635 views

Perspective

Published on 18 Nov 2025

Radioprotection redefined: drug discovery at the intersection of tardigrade biology and translational pharmacology

in Translational Pharmacology

Zhitao Cui
Cong Lin
Huiying Zhao
Xiaohui Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1713914

1,925 views

Original Research

Published on 18 Nov 2025

Efficacy and safety of omadacycline for the treatment of infectious diseases: a real-world, retrospective study of 2587 patients

in Pharmacology of Infectious Diseases

Jian Liu
Jiayi Liu
Huangyi Li
Jiali Pang
Siyun Chen
Jianming Liu
Aijun Ouyang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1706601

1,489 views

Original Research

Published on 18 Nov 2025

Pricing, price revision, and clinical value of anticancer drugs in Japan: a retrospective observational study

in Drugs Outcomes Research and Policies

Jiaqi He
Haibo Wei
Yue Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1641775

1,388 views

Review

Published on 17 Nov 2025

Harnessing the multi-targeted potential of rehmanniae radix natural products against renal fibrosis: a mechanistic review

in Ethnopharmacology

Keqin Zhao
Han Zhu
Liping Zheng
Wenru Wang
Peng Liu
Renhuan Yu
Xiaobei Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1690036

1,768 views

Review

Published on 17 Nov 2025

Endoplasmic reticulum oxidoreductin 1α as a potential therapeutic target in diseases: from oxidative protein folding to pathophysiological mechanisms

in Cardiovascular and Smooth Muscle Pharmacology

Fang He
Xiaoyue Ge
Xiaohui Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1709284

1,263 views

Review

Published on 17 Nov 2025

An overview of the mechanistic approaches of antifungal nanomaterials

in Translational Pharmacology

Sarmistha Saha
Nadezhda Sachivkina
Regina Gurina
Ekaterina Neborak
Natallia Zhabo
Marina Avdonina
Maria Molchanova

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1701446

2,122 views

Review

Published on 17 Nov 2025

Advances in traditional Chinese medicine for burn treatment: mechanisms, therapeutic approaches, and innovative preparations

in Ethnopharmacology

Ying Liu
Caiyuan Yu
Tong Dou
Yang Shen
He Li
Mengyan Liu
Wenying Xie
Weijia Zeng
Zizhao Feng
Ming Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1651219

2,872 views

Original Research

Published on 17 Nov 2025

1H-NMR-based metabolomics study of Rifafour in a healthy Kramnik (C3HeB/FeJ) tuberculosis mouse model

in Drug Metabolism and Transport

Oluwadara Pelumi Omotayo
Siyethemba Bhengu
Yolandy Lemmer
Kobus Venter
Shayne Mason

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1661938

1,463 views

Original Research

Published on 17 Nov 2025

Xinli formula’s efficacy in heart failure: analysis via Guangdong TCM hospital database

in Ethnopharmacology

Haiming Cao
Jiongming Zhang
Tong Zhang
Xiankun Chen
Tong Liu
Wenjing Xu
Yi Zhu
Wei Jiang
Weihui Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1661625

1,189 views

Review

Published on 17 Nov 2025

Ethnomedicinal, phytochemical, pharmacological, and conservation studies of an endangered plant: the desert teak (Tecomella undulata (Sm.) Seem.)

in Ethnopharmacology

Sharad Vats
Nikkee Bhandari
Showkat Ahmad Ganie
Mushtaq Ahmad Mir
Nasreena Bashir

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1665446

1,733 views

Original Research

Published on 17 Nov 2025

Comparative efficacy and safety of botanical drugs for mild cognitive impairment: a systematic review and network meta-analysis

in Ethnopharmacology

Yifan Yang
Haixia Wang
Jianmeng Lü
Hui Zhang
Tao Wang
Yongmei Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657169

2,465 views
1 citation

Original Research

Published on 17 Nov 2025

Terminal complement inhibition in atypical haemolytic uremic syndrome: a single-centre experience

in Cardiovascular and Smooth Muscle Pharmacology

Valentin D. Mocanu
Bogdan M. Sorohan
Elena G. Micu
Sonia Bălănică
Bogdan Obrişcă
Roxana A. Jurubiță
Camelia A. Achim
Adrian C. Lungu
Cristina S. Căpuşă
Gabriel Mircescu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1683188

1,796 views

Original Research

Published on 17 Nov 2025

Genetic characterization of pediatric B-cell acute lymphoblastic leukemia in Argentina uncovers molecular heterogeneity and novel variants

in Pharmacology of Anti-Cancer Drugs

María Sol Ruiz
Ezequiel Sosa
Daniel Avendaño
Ignacio Gomez Mercado
María Laura Lacreu
Cecilia Riccheri
Virginia Schuttenberg
Luis Aversa
Elba Vazquez
Geraldine Gueron

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1701680

1,473 views

Original Research

Published on 17 Nov 2025

SZBC-AI4TCM: a comprehensive web-based computing platform for traditional Chinese medicine research and development

in Ethnopharmacology

Jidong Lang
Kaimin Guo
Jinna Yang
Pengcheng Yang
Yu Wei
Jingwen Han
Shuang Zhao
Zhihong Liu
Haowei Yi
Xin Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1698202

1,913 views

Editorial

Published on 17 Nov 2025

Editorial: Histone modifications in cancer

in Pharmacology of Anti-Cancer Drugs

Jiaqian Luo
Sizhi P. Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1727417

899 views

29,512 articles

articles

Predicting tigecycline-related adverse events in infected patients: a machine learning approach with clinical interpretability

Constructing an evaluation framework for primary pharmacovigilance systems in developing countries: a case study from China

Glial cell line-derived neurotrophic factor inhibits mast-cell-like RBL-2H3 cells activation via Ca2+-mediated degranulation and Ca2+/CaMKⅡ/JNK pathway

From bench to bedside, boswellic acids in anti-inflammatory therapy — mechanistic insights, bioavailability challenges, and optimization approaches

Curcumol alleviates endometriosis via correcting the aberrant activation of Fas/RIPK1-mediated PANoptosis

Substandard and falsified medicines in Africa: healthcare systems challenges, supply chain issues, regulatory challenges and strategies to increase access to quality medicines

In vivo pharmacokinetic evaluation of molnupiravir in patients with severe chronic kidney disease

Impact of parathyroid Hormone’s dose, timing, and delivery mode on osteoclastogenesis and osteogenesis using a human periodontal ligament fibroblast model

Comparison of short-term and long-term renal function effects of vasopressin and norepinephrine in patients with septic shock: a systematic review and meta-analysis

Radioprotection redefined: drug discovery at the intersection of tardigrade biology and translational pharmacology

Efficacy and safety of omadacycline for the treatment of infectious diseases: a real-world, retrospective study of 2587 patients

Pricing, price revision, and clinical value of anticancer drugs in Japan: a retrospective observational study

Harnessing the multi-targeted potential of rehmanniae radix natural products against renal fibrosis: a mechanistic review

Endoplasmic reticulum oxidoreductin 1α as a potential therapeutic target in diseases: from oxidative protein folding to pathophysiological mechanisms

An overview of the mechanistic approaches of antifungal nanomaterials

Advances in traditional Chinese medicine for burn treatment: mechanisms, therapeutic approaches, and innovative preparations

1H-NMR-based metabolomics study of Rifafour in a healthy Kramnik (C3HeB/FeJ) tuberculosis mouse model

Xinli formula’s efficacy in heart failure: analysis via Guangdong TCM hospital database

Ethnomedicinal, phytochemical, pharmacological, and conservation studies of an endangered plant: the desert teak (Tecomella undulata (Sm.) Seem.)

Comparative efficacy and safety of botanical drugs for mild cognitive impairment: a systematic review and network meta-analysis

Terminal complement inhibition in atypical haemolytic uremic syndrome: a single-centre experience

Genetic characterization of pediatric B-cell acute lymphoblastic leukemia in Argentina uncovers molecular heterogeneity and novel variants

SZBC-AI4TCM: a comprehensive web-based computing platform for traditional Chinese medicine research and development

Editorial: Histone modifications in cancer