Frontiers in Pharmacology

Clinical Trial

Accepted on 09 Feb 2026

Clinical Efficacy and Mechanistic Study of Fulvning Granules in Symptomatic Atrial Fibrillation: A Randomized Controlled Trial with Untargeted Metabolomics Analysis

in Ethnopharmacology

Jinru Tao
Keke Liu
Tianyi Chen
Yulai Zhan
Chunrui Hu
Qiuting Yu
Yinyifan Zhou
Xue Liu
Zilin Ma
Na Zhang

Frontiers in Pharmacology

Review

Accepted on 09 Feb 2026

PI3K/AKT Signaling Pathway: New Strategies for Treating Atherosclerosis with Plant-Derived Compounds

in Ethnopharmacology

Lin Zhu
Qiuhan Chen
Boyu Wang
Jiamei Fu
Zhiping Liu
Yingying Cui
Ruiting Zhang
Fengwei Liu
Si Ying Niu
Yabin Zhou

Frontiers in Pharmacology

Editorial

Accepted on 09 Feb 2026

Editorial-Translational potential of novel biomarkers and molecular targets in lifestyle diseases

in Experimental Pharmacology and Drug Discovery

Atin Kalra
Pradip Nirbhavane
CHHANDA CHARAN DANTA
Dr Priyanka Saroj
ravinder Dharavath

Frontiers in Pharmacology

220 views

Systematic Review

Accepted on 09 Feb 2026

Cardioprotective Effects of Puerarin Against Myocardial Ischemia-Reperfusion Injury: A Preclinical Systematic Review and Meta-Analyzes

in Ethnopharmacology

Ding Chen
Zheng Liang
Xingye Wang
Cong Xue
Zhao shi
Ming Yao
Yiqiang Wang
Lihong Jiang

Frontiers in Pharmacology

Correction

Accepted on 09 Feb 2026

Correction: Erythropoietin Mitigates Diabetic Nephropathy by Restoring PINK1/Parkin-Mediated Mitophagy

in Renal Pharmacology

Xinyao Yi
Yan Wenhui
Tingli Guo
Na Liu
Zhuanzhuan Wang
Jia Shang
Xiaotong Wei
Xin Cui
Yuzhuo Sun
Shuting Ren

Frontiers in Pharmacology

Original Research

Accepted on 09 Feb 2026

The mechanism of Vicenin-2 in ameliorating skin photoaging: involvement of m6A-modified macrophage polarization

in Experimental Pharmacology and Drug Discovery

Yan Zhou
Wenlong Shuai
Xinyi Peng
Ruishan Li
Meng Chen
Bowen Tan
Yunzhu Mu
Xi Duan

Frontiers in Pharmacology

Clinical Trial

Accepted on 09 Feb 2026

Low-dose naltrexone as an adjunctive treatment for major depressive disorder: Findings from a randomized, double-blind, placebo-controlled hybrid parallel-arm study

in Inflammation Pharmacology

Ben Moloney
Anna Forsyth
Rachael Sumner
Stephanie Glover
Nicholas Hoeh
Frederick Sundram
Alana Cavadino
Suresh Muthukumaraswamy
Joanne Lin

Frontiers in Pharmacology

132 views

Original Research

Accepted on 09 Feb 2026

Network toxicology reveals key genes of amiodarone induced pulmonary fibrosis: based on machine learning and SHAP analysis

in Respiratory Pharmacology

Ying Liu
Xiaoyan Yan
Rui Fan

Frontiers in Pharmacology

Brief Research Report

Accepted on 09 Feb 2026

Effectiveness and safety of cemiplimab in locally advanced and metastatic cutaneous squamous cell carcinoma

in Pharmacology of Anti-Cancer Drugs

Gabriele Roccuzzo
Eleonora Bongiovanni
Giovanni Actis-Giorgetto
Chiara Astrua
Matteo Giovanni Brizio
Giovanni Cavaliere
Paolo Fava
SIMONE RIBERO
Pietro Quaglino

Frontiers in Pharmacology

Original Research

Accepted on 09 Feb 2026

A Retrospective Analysis of Outpatient Use of Small-Molecule Targeted Inhibitors for Lymphoma Across Six Regions of China (2016–2022)

in Pharmacology of Anti-Cancer Drugs

Chen Bo
Liying Chen
Ping Chen
王晨
Chang-Wei Yang
Yan Hu
Ran Wei
Liu-Cheng Li
Zhen-Lin Fu

Frontiers in Pharmacology

Review

Accepted on 09 Feb 2026

Epigenetic and Mitoepigenetic Regulation in Cancer and Therapeutic Perspectives

in Pharmacology of Anti-Cancer Drugs

Selcen Celik Uzuner
Ihsan Nalkiran
Ugur Uzuner
Hatice Sevim Nalkiran

Frontiers in Pharmacology

111 views

Review

Accepted on 09 Feb 2026

Epithelial-mesenchymal transition and sunitinib resistance in Renal Cell Carcinoma: mechanisms and therapeutic strategies

in Pharmacology of Anti-Cancer Drugs

Mingkai Zhang
Yirui Zhang
Fan Shen
Maoli Yan
Pengfei Cheng
Jing Teng
Mengqin Zou
Wendi Yao
Zhifeng Wang
Wen Li

Frontiers in Pharmacology

Original Research

Accepted on 09 Feb 2026

Therapeutic relevance of an EU-GMP certified Cannabis sativa L. strain in a dual in vivo model of cognitive impairment and chronic neuropathic pain

in Ethnopharmacology

Ivona Costachescu
Gogu Maria-Raluca
Gabriela Dumitrita Stanciu
Carmen Solcan
Loredana Horodnicu
Andrei Szilagyi
Vlad Constantin Craciun
Daniela-Carmen Ababei
Bogdan Ionel Tamba

Frontiers in Pharmacology

105 views

Review

Accepted on 09 Feb 2026

Advances in Managing Knee Osteoarthritis: Exploring Ultrasound-Guided Radiofrequency Thermocoagulation and its Molecular Impact

in Translational Pharmacology

Xuetian Zhou
Chao Quan
Xiuling Luo

Frontiers in Pharmacology

Case Report

Accepted on 09 Feb 2026

Rhabdomyolysis Secondary to Chlorpheniramine Maleate Toxicity:a case report

in Predictive Toxicology

安阳卢
Rong Wu

Frontiers in Pharmacology

111 views

Original Research

Accepted on 09 Feb 2026

Targeting the NSUN2–DHODH Axis Reverses Ferroptosis Resistance and Oxaliplatin Resistance in Colorectal Cancer

in Pharmacology of Anti-Cancer Drugs

Junyi Zhang
Junxiao Shen
Tangye Zeng
Chang Gao
Biao Sheng
Junliang Li
Weiqi Zeng
Jieyi Shen
Chong Shen
Jiaojiao Wang

Frontiers in Pharmacology

Perspective

Accepted on 09 Feb 2026

Perspective: Systems Biology Can Provide Guidance to Synthetic Biology in the Pursuit of New Drug Targets

in Experimental Pharmacology and Drug Discovery

Eberhard Otto Voit

Frontiers in Pharmacology

Original Research

Accepted on 09 Feb 2026

Analysis of Risk Factors for Herb-Induced Liver Injury: A Retrospective Study from China

in Gastrointestinal and Hepatic Pharmacology

Peng Chong Wang
Xinyan Liang
Guangyu Cheng
Qimeng Fan
Qing Li
Fengshou Dai
Yajun Liu
Zhenzhou Jiang
Tianjiong Luo
Jingwen Hu

Frontiers in Pharmacology

Original Research

Accepted on 09 Feb 2026

Adenosine A2A Receptors Regulate D2-type Medium Spiny Neurons in the Nucleus Accumbens to Mediate Pain and Depression Comorbidity

in Neuropharmacology

Dongyu Zhou
Xiaona Yang
Lingzhen Song
Mengyu Wu
Hongxing Zhang
Jun-li Cao
Su Min

Frontiers in Pharmacology

Correction

Published on 09 Feb 2026

Correction: AI-assisted literature exploration of innovative Chinese medicine formulas

in Ethnopharmacology

Meng-Chi Chung
Li-Jen Su
Chien-Lin Chen
Li-Ching Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1788574

267 views

Original Research

Published on 09 Feb 2026

Early metoprolol use in ICU patients with congestive heart failure is associated with increased 30-day mortality: a causal machine learning study

in Pharmacoepidemiology

Yunzhu Chen
Tianyou Li

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1771969

298 views

Systematic Review

Published on 09 Feb 2026

Progress, critical challenges, and translational prospects of intranasal administration of botanical essential oils for the treatment of depression

in Ethnopharmacology

Kexin Cheng
Hongyi Zhao
Kui He
Xiuwen Xia
Yi Wang
Shuyu Wang
Weihong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1748824

532 views

Review

Published on 09 Feb 2026

Incorporating patient-reported outcome measures into routine paediatric pharmacovigilance: opportunities for safety monitoring with practical use scenarios from paediatric oncology

in Drugs Outcomes Research and Policies

Pedro Teodoro
Ricardo M. Fernandes
Inês Ribeiro
Renato Ferreira-da-Silva

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1719963

406 views

Original Research

Published on 09 Feb 2026

Changes in youth public psychiatric service utilization during the COVID-19 pandemic in Italy: an observational study

in Pharmacoepidemiology

Ippazio Cosimo Antonazzo
Carla Fornari
Manuel Zamparini
Giacomo Crotti
Alberto Zucchi
Pietro Ferrara
Alexandra Maria Piraino
Paolo Angelo Cortesi
Lorenzo Losa
Giampiero Mazzaglia

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1708009

371 views

29,512 articles

articles

Clinical Efficacy and Mechanistic Study of Fulvning Granules in Symptomatic Atrial Fibrillation: A Randomized Controlled Trial with Untargeted Metabolomics Analysis

PI3K/AKT Signaling Pathway: New Strategies for Treating Atherosclerosis with Plant-Derived Compounds

Editorial-Translational potential of novel biomarkers and molecular targets in lifestyle diseases

Cardioprotective Effects of Puerarin Against Myocardial Ischemia-Reperfusion Injury: A Preclinical Systematic Review and Meta-Analyzes

Correction: Erythropoietin Mitigates Diabetic Nephropathy by Restoring PINK1/Parkin-Mediated Mitophagy

The mechanism of Vicenin-2 in ameliorating skin photoaging: involvement of m6A-modified macrophage polarization

Low-dose naltrexone as an adjunctive treatment for major depressive disorder: Findings from a randomized, double-blind, placebo-controlled hybrid parallel-arm study

Network toxicology reveals key genes of amiodarone induced pulmonary fibrosis: based on machine learning and SHAP analysis

Effectiveness and safety of cemiplimab in locally advanced and metastatic cutaneous squamous cell carcinoma

A Retrospective Analysis of Outpatient Use of Small-Molecule Targeted Inhibitors for Lymphoma Across Six Regions of China (2016–2022)

Epigenetic and Mitoepigenetic Regulation in Cancer and Therapeutic Perspectives

Epithelial-mesenchymal transition and sunitinib resistance in Renal Cell Carcinoma: mechanisms and therapeutic strategies

Therapeutic relevance of an EU-GMP certified Cannabis sativa L. strain in a dual in vivo model of cognitive impairment and chronic neuropathic pain

Advances in Managing Knee Osteoarthritis: Exploring Ultrasound-Guided Radiofrequency Thermocoagulation and its Molecular Impact

Rhabdomyolysis Secondary to Chlorpheniramine Maleate Toxicity:a case report

Targeting the NSUN2–DHODH Axis Reverses Ferroptosis Resistance and Oxaliplatin Resistance in Colorectal Cancer

Perspective: Systems Biology Can Provide Guidance to Synthetic Biology in the Pursuit of New Drug Targets

Analysis of Risk Factors for Herb-Induced Liver Injury: A Retrospective Study from China

Adenosine A2A Receptors Regulate D2-type Medium Spiny Neurons in the Nucleus Accumbens to Mediate Pain and Depression Comorbidity

Correction: AI-assisted literature exploration of innovative Chinese medicine formulas

Early metoprolol use in ICU patients with congestive heart failure is associated with increased 30-day mortality: a causal machine learning study

Progress, critical challenges, and translational prospects of intranasal administration of botanical essential oils for the treatment of depression

Incorporating patient-reported outcome measures into routine paediatric pharmacovigilance: opportunities for safety monitoring with practical use scenarios from paediatric oncology

Changes in youth public psychiatric service utilization during the COVID-19 pandemic in Italy: an observational study