Frontiers in Pharmacology

Clinical Trial

Published on 17 Apr 2025

Analysis of sedative-hypnotic drug use trends in children and adolescents (2018–2023): a study based on outpatient prescription data from a general hospital

in Obstetric and Pediatric Pharmacology

Zhang Qingyu
Jiang Wenqing
Ma Le
Hou Yanbin
Miao Pingping
Lin Chen
Mao Jiaxin
Dai Ni
Yang Dalu
Tong Kanzhen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1563580

288 views

Original Research

Published on 17 Apr 2025

Polydatin attenuates Alzheimer’s disease induced by aluminum chloride in rats: evidence for its antioxidant and anti-inflammatory effects

in Ethnopharmacology

Seyede Nazanin Zarneshan
Sajad Fakhri
Amir Kiani
Fatemeh Abbaszadeh
Seyede Zahra Hosseini
Ehsan Mohammadi-Noori
Javier Echeverría

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1574323

270 views

Review

Published on 17 Apr 2025

Methyltransferase-like 3 is a target for the diagnose and therapy of clear cell renal carcinoma

in Renal Pharmacology

Dongqiong Xiao
Xiaojuan Su

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1534655

210 views

Review

Published on 17 Apr 2025

NLRP3 inflammasome as a therapeutic target in doxorubicin-induced cardiotoxicity: role of phytochemicals

in Cardiovascular and Smooth Muscle Pharmacology

Xiao-Peng Zhao
Lian Duan
Qian-Ru Zhao
Xing Lv
Nai-Yuan Tian
Sheng-Lei Yang
Kun Dong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1567312

208 views

Original Research

Published on 17 Apr 2025

Targeting PCNA/PARP1 axis inhibits the malignant progression of hepatocellular carcinoma

in Pharmacology of Anti-Cancer Drugs

Jipin Li
Tao Yong
Yali Chen
Tingyu Zeng
Kaifeng Zhang
Shuping Wang
Youcheng Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1571786

230 views

Original Research

Published on 17 Apr 2025

LINC01559 drives osimertinib resistance in NSCLC through a ceRNA network regulating miR-320a/IGF2BP3 axis

in Pharmacology of Anti-Cancer Drugs

Leidi Xu
Yibo Zhang
Liangliang Xing
Ying Zhou
Ning Chang
Hangtian Xi
Xiangrui Xu
Jian Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592846

291 views

Original Research

Published on 17 Apr 2025

Bee venom ameliorates gentamicin-induced kidney injury by restoring renal aquaporins and enhancing antioxidant and anti-inflammatory activities in rats

in Ethnopharmacology

Doaa Abdelrahaman
Obeid Shanab
Ahmed Abdeen
Afaf Abdelkader
Khalid M. Elazab
Hagar Kouriem
Zainab M. Maher
Amal S. Abu-Almakarem
Mohamed E. Mohamed
Yasser M. Elbastawisy

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1525529

614 views

Systematic Review

Published on 17 Apr 2025

The efficacy and safety of Chinese herbal medicine Shugan Sanjie decoction in the treatment of uterine fibroids: a systematic review and meta-analysis

in Ethnopharmacology

Yang Zhang
Junfan Wei
Chanchan Gao
Shenyang Feng
Haiying Wang
Junjie Chai
Yini Zhu
Yuan Yuan
Lirong Ren

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1508015

291 views

Original Research

Accepted on 16 Apr 2025

Administration of chiglitazar reverses chronic stress-induced depressive-like symptoms in mice via activation of hippocampal PPARα and BDNF

in Neuropharmacology

Jiu-Jian Zhou
Jie Zhao
Shang-Yan Gao
Yuan-Yuan Gao
Cheng Chen
Yi Ding
Zhonghua Wu
Pu-jian Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1587399

Original Research

Accepted on 16 Apr 2025

Integrating proteomics and network pharmacology to explore the relevant mechanism of Huangkui capsule in the treatment of chronic glomerulonephritis

in Renal Pharmacology

Changqing Wen
jia zou
jiaxuan li
fujiang wang
haitao ge

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1560420

Original Research

Accepted on 16 Apr 2025

Synergistic effect of hypoglycemic drugs in combination with phytochemicals, Clinacanthus nutans (Burm. f.) Lindau, ameliorates renal inflammation, fibrosis, and injury in type 2 diabetic rats

in Renal Pharmacology

Pongrapee Laorodphun
Saruda Thongyim
Sureeporn Suriyaprom
Pornchita Maphet
Yingmanee Tragoolpua
Thida Kaewkod
Aussara Panya
Phatchawan Arjinajarn

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558341

Mini Review

Accepted on 16 Apr 2025

Trace amine-associated receptors as potential targets for the treatment of anxiety and depression

in Neuropharmacology

Zelong Li
Luoting Wan
Jing Dong
Jinquan Li
Jianfeng Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1598048

Review

Accepted on 16 Apr 2025

Knowledge landscape of macrophage research in liver fibrosis: A bibliometric review of the literature from WoSCC

in Gastrointestinal and Hepatic Pharmacology

Yanbo Li
Zhengmin Cao
Yanping Lu
Chao Lei
Wenliang Lv

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1571879

Systematic Review

Accepted on 16 Apr 2025

Efficacy and Safety of Puerarin Injection as an Adjunctive Therapy for Chronic Heart Failure: A Systematic Review and Meta-Analysis

in Ethnopharmacology

Hesong Fan
Jingrong Yang
Huaizhe Wang
Shuli Zong
Yiwei Qu
Kefei Wang
Fengyi Zhang
Xiao Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1516059

Original Research

Accepted on 16 Apr 2025

Effect of Methotrexate/Dexamethasone Combination on Epithelial-Mesenchymal Transition and Inflammation Gene Expression of Human RPE Cells In-Vitro

in Inflammation Pharmacology

Fatemeh Sanie-Jahromi
Mahdi Ravankhah
Shafi Khani
Ahmad Razavizadegan
M Hossein Nowroozzadeh

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1569703

Original Research

Accepted on 16 Apr 2025

An Ethnopharmacological Survey Of Herbal Medicines Use Among Pregnant And Postpartum Women In Souss Massa (Morocco)

in Ethnopharmacology

Afaf Bouqoufi
Lahlou Laila
Fatima Ait el hadj
Saïd Boujraf
Mohammed Abdessadek
Youssef KHABBAL

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1567930