Frontiers in Pharmacology

Systematic Review

Accepted on 16 Apr 2025

Efficacy and safety of neoadjuvant PD-1 inhibitors or PD-L1 inhibitors combined with chemoradiotherapy for locally advanced rectal cancer: a systematic review and meta-analysis

in Pharmacology of Anti-Cancer Drugs

Jiaojiao Yu
Hua Zhu
Mingxu Li
Xiaoxia Tang
Ke Luan
Yinhuan Zhi
Shan Yin
Yuanqi Su
Jingyan Long
Jieru Quan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1570467

Review

Accepted on 16 Apr 2025

Therapeutic and Protective Approaches to Combat Campylobacter jejuni Infections

in Pharmacology of Infectious Diseases

Irshad Sharafutdinov
Linz Bodo
Nicole Tegtmeyer
Steffen Backert

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1572616

Original Research

Accepted on 16 Apr 2025

Trajectories of Potentially Inappropriate Medication Use among Older Adults in Saudi Arabia

in Drugs Outcomes Research and Policies

Fouad F. Jabri
Yajun Liang
Kristina Johnell
Jette Möller

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1568160

109 views

Clinical Trial

Accepted on 16 Apr 2025

Evaluation of the pharmacokinetic interactions of montmorillonite powder or loperamide on pyrotinib in healthy volunteers

in Drug Metabolism and Transport

YIKE WANG
Dai Li
Tong Zhang
Sumei Xu
Yanxin Zhang
Kaijing Zhao
Shaorong Li
Kai Shen
Xiaomin Li
Pingsheng Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1563556

103 views

Original Research

Accepted on 16 Apr 2025

Towards a Sustainable Rare Disease and Orphan Drug Ecosystem in Saudi Arabia: Policy Insights from a Multi-Stakeholder Workshop

in Drugs Outcomes Research and Policies

Ghada Mohammed Abozaid
Hussain Al-Omar
Abdulaziz Alrabiah
Asma Almuaither
Amy Jayne McKnight

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1583477

190 views

Original Research

Accepted on 16 Apr 2025

Liquid chromatography tandem mass spectrometry assay for the simultaneous determination of apalutamide and its active metabolite N-desmethyl apalutamide, and application in real world patients with castration-resistant prostate cancer

in Drug Metabolism and Transport

Yuxuan Zhu
Lu Chen
Wenqiang Chen
Dingyuan Yang
Lijuan Zhang
Jun Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1510583

Original Research

Accepted on 16 Apr 2025

CS-6-induced p62 accumulation exacerbates DNA damage in colorectal cancer

in Experimental Pharmacology and Drug Discovery

Yitong Gong
Menghan Dong
Xiaofei Feng
Naiyu Zhang
Xuehui Cui
Liushuyue Wang
Chiu-fai Kuok
Jiang Qing Ling
Sixue Bi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1568339

Original Research

Accepted on 16 Apr 2025

IGFBP5 mediates the therapeutic effect of isoliquiritigenin in myocardial ischemia-reperfusion injury via AKT/GLUT4 regulated insulin resistance

in Cardiovascular and Smooth Muscle Pharmacology

Jue Bai
Si-Yuan Yang
Shao-Mei Yu
Ying Cao
Xuan-Yi Hu
Xiong Chen
Ying-Nan Song
Hongjin Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1544869

Original Research

Published on 16 Apr 2025

Honeysuckle extracts as a potential inhibitor of SARS-CoV-2 infection

in Ethnopharmacology

Ping-Chang Lin
Ying-Ray Lee
Li-Teh Liu
Shyh-Shin Chiou
Po-Chih Chen
Ching-Yi Tsai
Jih-Jin Tsai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1517585

269 views

Original Research

Published on 16 Apr 2025

SUMOylation substrate encoding genes as prognostic biomarkers in pancreatic ductal adenocarcinoma with functional assessment of SAF-B2

in Pharmacology of Anti-Cancer Drugs

Xiangjun Wang
Chuanxin Yang
Yangming Liu
Jian Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532658

232 views

Review

Published on 16 Apr 2025

SREBP2 as a central player in cancer progression: potential for targeted therapeutics

in Pharmacology of Anti-Cancer Drugs

Ruiqi Chen
Tianyu Chen
Xiang Li
Junfeng Yu
Min Lin
Siqi Wen
Man Zhang
Jinchi Chen
Bei Yi
Huage Zhong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1535691

229 views

Review

Published on 16 Apr 2025

A crucial role of miR-155 in the pathomechanism of acute kidney injury

in Renal Pharmacology

Hui Wang
Jian Liao
Wei Wang
Jianhua Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1570000

215 views

Original Research

Published on 16 Apr 2025

Multi - dimensional mechanism analysis of Choerospondias axillaris (Roxb.) Burtt et Hill in treating kidney stones: network pharmacology, molecular docking and in vitro experimental verification

in Renal Pharmacology

Meiqi Qiu
Senhua Li
Yu Zhang
Jiaoxia Yan
Shiting Qin
Xijing Yin
Yujun Li
Chunhui Zeng
Ke Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1501386

327 views

Original Research

Published on 16 Apr 2025

Repurposing major metabolites of lamiaceae family as potential inhibitors of α-synuclein aggregation to alleviate neurodegenerative diseases: an in silico approach

in Experimental Pharmacology and Drug Discovery

Soham Bhattacharya
Neha Gupta
Adrish Dutta
Pijush Kanti Khanra
Ritesh Dutta
Jana Žiarovská
Nikolay T. Tzvetkov
Lucie Severová
Lenka Kopecká
Luigi Milella

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1519145

347 views

Original Research

Published on 16 Apr 2025

Dracaena trifasciata (Prain) Mabb leaf extract protects MIN6 pancreas-derived beta cells against the diabetic toxin streptozotocin: role of the NF-κB pathway

in Ethnopharmacology

Christiaan Warner Hoornenborg
Nur Qomariyah
Herson Antonio González-Ponce
André Petrus Van Beek
Han Moshage
Gertjan Van Dijk

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1485952

574 views

Original Research

Published on 16 Apr 2025

Association of long-term use of dipeptidyl peptidase-4 inhibitors with the risk of diabetic retinopathy in patients with diabetes mellitus: a real-world evidence study

in Pharmacoepidemiology

Yu-Ching Li
Yu-Hsiang Kuan
Yih Yang
Shuo-Yan Gau
Kun-Yu Su
Tung-Han Tsai
Kuang-Hua Huang
Chien-Ying Lee

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1518545

272 views