Frontiers in Pharmacology

Original Research

Published on 09 Feb 2026

1-Nitropyrene induces acute lung injury via SYVN1/Caspase-11-mediated apoptosis and pyroptosis in pulmonary epithelial cells

in Inflammation Pharmacology

Zhao-Lei Ding
Yi-Chen Ma
Chuan-Mei Liu
Xiu Lu
Rong-Rong Wang
Min-Min Tang
Dong-Xu Hua
Ling Zheng
Hui Zhao
Lin Fu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1723593

412 views

Original Research

Published on 09 Feb 2026

Safety of individualized herbal medicine for dysmenorrhea: pharmacovigilance from South Korea’s national pilot

in Ethnopharmacology

Minjung Park
Yongjoo Kim
Nan-He Yoon
Kyeore Bae
Junhyeok Yi
Sujin Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1722249

831 views

Review

Published on 09 Feb 2026

Piezo1 as a mechanical checkpoint in T cell immunotherapy for solid tumors

in Pharmacology of Anti-Cancer Drugs

Xinmu Cui
Jianan Zhao
Huajie Tian

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1722027

356 views

Original Research

Published on 09 Feb 2026

Targeted lipidomics meets transcriptomics: how cinobufagin rewires fatty acid, sphingolipid, and glycerophospholipid metabolism to combat hepatoma cell growth

in Pharmacology of Anti-Cancer Drugs

Wanjun Shao
Congying Yu
Rufei Xu
Xiaoqian Rong
Ailin Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1664915

381 views

Review

Published on 09 Feb 2026

Drug resistance mechanisms in Mycobacterium tuberculosis infection and challenges in vaccine development

in Pharmacology of Infectious Diseases

Shuying Zhang
Juan Cheng
Yuanyuan Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1762214

504 views

Brief Research Report

Published on 09 Feb 2026

Isoniazid subverting erythrocyte homeostasis: implications for tuberculosis therapy

in Pharmacology of Infectious Diseases

Muhammad Sikandar
Maria Fatima
Kashif Jilani
Li Xing

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1721617

431 views

Review

Published on 09 Feb 2026

Signaling network inhibition by selected traditional Chinese medicine preparations: a novel multi-target paradigm for colorectal cancer therapy

in Ethnopharmacology

Mingming Zhang
Haoyang Wang
Junying Pan
Yuzhe Jin
Zengde Tan

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1719306

248 views

Original Research

Published on 09 Feb 2026

Pharmacokinetics and nephrotoxicity of cisplatin modulated by combination therapy with brusatol

in Ethnopharmacology

Nan Guo
Yahui Zhang
Guiyan Yuan
Xiaoran Zhang
Wen Zhang
Qing Wen

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1708101

254 views

Mini Review

Published on 09 Feb 2026

Pharmacogenomics of risperidone in autism spectrum disorder: a minireview

in Pharmacogenetics and Pharmacogenomics

Caroline Rafaelli de Lima Honório
Beatriz Gafanhão Bobadilha
Melina Pinheiro Conscetta
Felipe De Mello Silveira
Francisco Durigon
Aline Cristiane Planello

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1768109

482 views

Original Research

Published on 09 Feb 2026

Tumour microenvironment and HER2-low status dictate response and resistance to anthracycline-taxane chemotherapy in premenopausal TNBC: a retrospective multicohort study

in Pharmacology of Anti-Cancer Drugs

Shuanglong Cai
Shaohong Yu
Quan Zhou
Fangyuan Kuang
Lingyan Rao
Zhen Fang
Xiaoxin Zheng
Yong Shi
Jingdan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1752328

295 views

Original Research

Published on 09 Feb 2026

Unraveling the role of 3-mercaptopyruvate sulfurtransferase-derived hydrogen sulfide in triple-negative breast cancer chemoresistance

in Translational Pharmacology

Sousanna Hakim
Danira A. Habashy
Kelly Ascenção
Rana A. Youness
Carole Bourquin
Csaba Szabo
Mohamed Z. Gad
Reham M. Abdelkader

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1748950

397 views

Original Research

Published on 09 Feb 2026

Crocin protects against smoke-induced chronic obstructive pulmonary disease by regulating AKT1

in Ethnopharmacology

Yuehong Zhu
Yuntao Jiang
Jieping Xu
Sicheng Yan
Zhihong Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1687752

388 views

Original Research

Published on 09 Feb 2026

Characterization and anti-inflammatory studies of supramolecular assemblies of chlorogenic acids with metal ions

in Inflammation Pharmacology

Zhen-Min Zhang
Ru-Yue Zhang
Lian Zhu
Zi-Xuan Liu
Han-Xiu Deng
Jie-Fu Tang
Jia-Yu Zhang
Wei Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1726226

333 views

Original Research

Published on 09 Feb 2026

Predictive modelling of the dynamics of antimicrobial resistance: creation of a bank of renewable models based on machine learning

in Drugs Outcomes Research and Policies

M. A. Arepyeva
A. Y. Kuzmenkov
A. A. Starostenkov
A. S. Kolbin
Y. E. Balykina
Yu M. Gomon
A. A. Kurylev
R. S. Kozlov
S. V. Sidorenko

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1715346

338 views

Systematic Review

Published on 09 Feb 2026

Global Panoramic analysis of clinical research in cell therapy: clinical trial landscape, marketed products, and regulatory trends

in Experimental Pharmacology and Drug Discovery

Mengmeng Wang
Tiange Zhou
Sijia Liu
Wanwan Xiang
Kewen Xie
Xiaoqiong Zhang
Wenxin Hu
Mengling Fang
Ziyue Zhang
Meimei Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1715984

457 views

Original Research

Published on 09 Feb 2026

Minnelide ameliorates Col4a5+/− mice by upregulating Col4a5 and alleviating endoplasmic reticulum stress

in Renal Pharmacology

Bao-wei Ji
Jun-chao Liu
Xue Wang
Ye Yin
Jing-jia Zhang
Fu-jie Wen
Hong Xu
Qian Shen
Jian Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1761502

365 views

Systematic Review

Published on 09 Feb 2026

Efficacy and safety of Salvia miltiorrhiza and ligustrazine injection for heart failure: a systematic review and meta-analysis

in Ethnopharmacology

Pingping Huang
Gaocan Ren
Yifei Wang
Yicheng Liu
Hongwei Zhang
Jiacong Wang
Jinhui Zhang
Yuan Zheng
Lijun Guo
Xiaochang Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1692629

379 views

Original Research

Accepted on 06 Feb 2026

Asiaticoside promotes intestinal epithelial proliferation and barrier function in ischemia/reperfusion injury by activating FoxM1

in Integrative and Regenerative Pharmacology

Guo Zu
Chenglin Zhao
Qingyu Du
Yuhang Wu
Xiangwen Zhang

Frontiers in Pharmacology

135 views

Editorial

Accepted on 06 Feb 2026

Editorial: Pharmacological and Nutritional Approaches to Metabolic Associated Fatty Liver Disease: A Step Towards Achieving SDG 3

in Gastrointestinal and Hepatic Pharmacology

Mahmut Bodur
Bojana B Vidovic
Anastasios Nikolaou
Birsen Yilmaz

Frontiers in Pharmacology

124 views

Original Research

Accepted on 06 Feb 2026

Intranasal Delivery of the NMDA Receptor Antagonist MK-801 Attenuates Ultra-Acute Excitotoxic Neurochemical Responses After Concussion in Rats: Comparative Pharmacological Evaluation Against Ketamine

in Neuropharmacology

Ian Masse
Luc Moquin
Caroline Bouchard
Laurianne Legroux
Alain Gratton
Louis De Beaumont

Frontiers in Pharmacology

175 views

Review

Accepted on 06 Feb 2026

Gut Microbiota and Spleen-Strengthening and Dampness-Dispelling Therapies in Obesity and Related Metabolic Disorders: Key Mechanisms and Therapeutic Potential

in Ethnopharmacology

Huiyi Peng
Jincheng Jiang
Zhoujin Tan
Ping Jiang

Frontiers in Pharmacology

224 views

Original Research

Accepted on 06 Feb 2026

Network toxicology and single-cell analysis reveal key gene-mediated bisphenol A interference with granulosa cell function in Polycystic Ovary Syndrome

in Obstetric and Pediatric Pharmacology

Yan Zhang
Yuan Lin
Xiumei Xiong
Xiujuan Chen
Xiaoqing Liu
Hailong Huang

Frontiers in Pharmacology

124 views

Clinical Trial

Accepted on 06 Feb 2026

Serum levels of S100B in patients with chronic schizophrenia during treatment augmentation with sarcosine: results of the double-blind, randomized, placebo-controlled PULSAR study

in Neuropharmacology

Agnieszka Pawlak
Adam Wysokinski
Dominik Strzelecki

Frontiers in Pharmacology

124 views

Original Research

Published on 06 Feb 2026

Components of Panax ginseng and Rhodiola rosea regulate mitophagy via the SIRT1/3-PGC-1α-NRF2 pathway to improve myocardial ischemia-reperfusion injury

in Ethnopharmacology

Ming Yao
Xiaoli Wang
Hongyu Wei
Lisha Wang
Dongze Zhang
Zheng Liang
Rong He
Yuan He
Lihong Jiang
Yingzi Cui

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1716078

786 views

29,512 articles

articles

1-Nitropyrene induces acute lung injury via SYVN1/Caspase-11-mediated apoptosis and pyroptosis in pulmonary epithelial cells

Safety of individualized herbal medicine for dysmenorrhea: pharmacovigilance from South Korea’s national pilot

Piezo1 as a mechanical checkpoint in T cell immunotherapy for solid tumors

Targeted lipidomics meets transcriptomics: how cinobufagin rewires fatty acid, sphingolipid, and glycerophospholipid metabolism to combat hepatoma cell growth

Drug resistance mechanisms in Mycobacterium tuberculosis infection and challenges in vaccine development

Isoniazid subverting erythrocyte homeostasis: implications for tuberculosis therapy

Signaling network inhibition by selected traditional Chinese medicine preparations: a novel multi-target paradigm for colorectal cancer therapy

Pharmacokinetics and nephrotoxicity of cisplatin modulated by combination therapy with brusatol

Pharmacogenomics of risperidone in autism spectrum disorder: a minireview

Tumour microenvironment and HER2-low status dictate response and resistance to anthracycline-taxane chemotherapy in premenopausal TNBC: a retrospective multicohort study

Unraveling the role of 3-mercaptopyruvate sulfurtransferase-derived hydrogen sulfide in triple-negative breast cancer chemoresistance

Crocin protects against smoke-induced chronic obstructive pulmonary disease by regulating AKT1

Characterization and anti-inflammatory studies of supramolecular assemblies of chlorogenic acids with metal ions

Predictive modelling of the dynamics of antimicrobial resistance: creation of a bank of renewable models based on machine learning

Global Panoramic analysis of clinical research in cell therapy: clinical trial landscape, marketed products, and regulatory trends

Minnelide ameliorates Col4a5+/− mice by upregulating Col4a5 and alleviating endoplasmic reticulum stress

Efficacy and safety of Salvia miltiorrhiza and ligustrazine injection for heart failure: a systematic review and meta-analysis

Asiaticoside promotes intestinal epithelial proliferation and barrier function in ischemia/reperfusion injury by activating FoxM1

Editorial: Pharmacological and Nutritional Approaches to Metabolic Associated Fatty Liver Disease: A Step Towards Achieving SDG 3

Intranasal Delivery of the NMDA Receptor Antagonist MK-801 Attenuates Ultra-Acute Excitotoxic Neurochemical Responses After Concussion in Rats: Comparative Pharmacological Evaluation Against Ketamine

Gut Microbiota and Spleen-Strengthening and Dampness-Dispelling Therapies in Obesity and Related Metabolic Disorders: Key Mechanisms and Therapeutic Potential

Network toxicology and single-cell analysis reveal key gene-mediated bisphenol A interference with granulosa cell function in Polycystic Ovary Syndrome

Serum levels of S100B in patients with chronic schizophrenia during treatment augmentation with sarcosine: results of the double-blind, randomized, placebo-controlled PULSAR study

Components of Panax ginseng and Rhodiola rosea regulate mitophagy via the SIRT1/3-PGC-1α-NRF2 pathway to improve myocardial ischemia-reperfusion injury