Frontiers in Pharmacology

Review

Published on 23 Oct 2025

Diabetes mellitus-driven pulmonary injury: multidimensional mechanisms linking metabolic dysregulation to gut-lung axis and promising therapies

in Respiratory Pharmacology

Jiacheng Sun
Junyang Chen
Yuntian Shen
Xinlei Yao
Hualin Sun
Bingqian Chen
Jian Feng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1689522

2,308 views

Original Research

Published on 23 Oct 2025

Anti-convulsant efficacy of long-acting injectable cannabidiol formulation (IVL5005) in the pentylenetetrazol-induced convulsions, with pharmacokinetic characterization

in Experimental Pharmacology and Drug Discovery

Soyoung Youm
Joo Young Cha
Slgirim Lee
Young Dai Seo
Kun Hee Park
Aeri Song
Hyun-Je Park
Woo Chan Son
Juhee Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1692123

1,998 views

Original Research

Published on 23 Oct 2025

Modulatory efficacy of bone metabolism and safety of denosumab versus zoledronic acid in the treatment of bone and joint osteoporosis in elderly men

in Experimental Pharmacology and Drug Discovery

Jing He
Yuhui Mao
Wanran Gong
Haitao Zhu
Peng Xiang
Shui Wang
Xiaofeng Dai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1666421

2,010 views

Mini Review

Published on 23 Oct 2025

Circadian rhythm in mycotoxin-induced immunotoxicity: an emerging regulatory axis?

in Predictive Toxicology

Li You
Eugenie Nepovimova
Klara Sklenarikova
Qinghua Wu
Kamil Kuca

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1700863

1,489 views

Original Research

Published on 23 Oct 2025

Implementation and impact analysis of a clinical pharmacy ambulatory: a two-year experience

in Pharmacoepidemiology

Daniele Mengato
Laura Camuffo
Federica Todino
Luisella Cordiano
Domenica Condello
Catia Bucciol
Franca Benini
Francesco Paolo Russo
Alberto Cipriani
Stefano Sartori

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1706056

1,650 views

Original Research

Published on 23 Oct 2025

Development and validation of a UHPLC-QqQ-MS/MS method for simultaneous determination of fifteen major components from Oroxyli seed extract in rat plasma and its application in the pharmacokinetic study

in Ethnopharmacology

Zhenguo Lv
Kaili Zhang
Zijing Zhang
Jinyue Ma
Wenwen Li
Lu Chen
Wenhan Lin
Yameng Zhu
Minglei Ge
Huizi Ouyang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1691629

1,370 views

Original Research

Published on 23 Oct 2025

Integrated chemometric evaluation of morphological traits, chemical composition, and hepatotoxicity of Polygonum multiflorum

in Predictive Toxicology

Yanyi Li
Qi Wang
Yanrong Yang
Xiaobin Huang
Yujie Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1666300

1,192 views

Original Research

Published on 23 Oct 2025

Adherence, satisfaction, and quality of life in Wilson disease patients after switching to trientine tetrahydrochloride: observational data from a dual cohort study

in Drugs Outcomes Research and Policies

Valentina Medici
Nora Cazzagon
Pier M. Battezzati
Andrea Crosignani
Alberto Civolani
Emanuela Bonaiuto
Renata D’Incà
Emanuela Vargiu
Fabio Tedone
Stefania Lopatriello

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1515686

1,566 views

Systematic Review

Published on 22 Oct 2025

Tongxinluo capsule for acute myocardial infarction: a systematic review and meta-analysis

in Ethnopharmacology

Yang Wu
Jingxue Guo
Jiasai Fan
Xian Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1632809

2,113 views

Mini Review

Published on 22 Oct 2025

Effect of formononetin on progressive pulmonary pathologies: multitarget mechanisms and therapeutic prospects

in Ethnopharmacology

Dan Yan
Saibin Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1645964

1,970 views

Correction

Published on 22 Oct 2025

Correction: Therapeutic effects of Eucommia ulmoides extract on osteoporosis rat models: a systematic review and meta-analysis

in Ethnopharmacology

Zhen Chen
Chuan Leng
Tang Rui
Chaoqun Feng
Tong Li
Yang Yu
Lei Zhong
Xiaohong Fan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1711404

875 views

Correction

Published on 22 Oct 2025

Correction: Targeting digestive system cancers with isoliquiritigenin: a comprehensive review of antitumor mechanisms

in Pharmacology of Anti-Cancer Drugs

Zhichun Li
Ruohan Feng
Jinze Li
Jinglu Bai
Nuo Li
Zhenhua Cui
Xiaobin Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1705251

698 views

Original Research

Published on 22 Oct 2025

CU06-1004 inhibits the progression of chronic colitis and colitis-associated colorectal cancer by suppressing inflammation

in Inflammation Pharmacology

Dongyeop Kim
Yeomyeong Kim
Haiying Zhang
Ye-Seul Kim
Minyoung Noh
Cho-Rong Bae
Young-Guen Kwon
Sang-Jun Ha

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1684870

2,033 views
1 citation

Correction

Published on 22 Oct 2025

Correction: Psychiatric adverse events associated with infliximab: a cohort study from the French nationwide discharge abstract database

in Drugs Outcomes Research and Policies

Eve-Marie Thillard
Sophie Gautier
Evgeniya Babykina
Louise Carton
Ali Amad
Guillaume Bouzillé
Jean-Baptiste Beuscart
Emmanuel Chazard

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1719490

736 views

Case Report

Published on 22 Oct 2025

Case Report: Extended survival in KRAS-G12V NSCLC with leptomeningeal metastasis through integrated intrathecal chemotherapy and systemic therapies

in Pharmacology of Anti-Cancer Drugs

Yun Chen
Zhiquan Qin
Luying Zhan
Xinchang Guo
Koji Fukuda
Qihao Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1632369

2,174 views
1 citation

Review

Published on 21 Oct 2025

The chemical structure, pharmacological activity, and clinical progress of Gentianae Radix et Rhizoma

in Ethnopharmacology

Hongfang Liu
Xiao Liu
Sheng Liu
Feng Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1656493

2,296 views

Systematic Review

Published on 21 Oct 2025

Comparative efficacy and safety of Xuebijing injection as adjuvant therapy in sepsis-associated acute kidney injury: a systematic review and meta-analysis

in Ethnopharmacology

Bofei Shu
Xu Zhou
Jing Fan
Can Yang
Wei Deng
Bangjiang Fang
Huan Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1643557

2,295 views
1 citation

Original Research

Published on 21 Oct 2025

Anti-obesity effects of Wumeishanzhayin: an integrated lipidomics and transcriptomics study

in Ethnopharmacology

Xiao Huang
Chunling Liao
Bo Peng
Jin Wang
Yong Zhang
Qingman He
Sijie Dang
Mei Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1697683

1,615 views

Original Research

Published on 21 Oct 2025

NeuproGemp, a polyphenol-rich botanical formula, ameliorates Alzheimer’s-like pathology in APP/PS1 mice via inhibition of human glutaminyl cyclase

in Neuropharmacology

Tien-Sheng Tseng
Chia-Ching Liaw
Young-Ji Shiao
Ya-I Huang
Yu-Hsiu Cheng
Wang-Chuan Chen
Keng-Chang Tsai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1673532

6,408 views

Original Research

Published on 21 Oct 2025

Investigation and analysis on the charging status and standard of pharmacy intravenous admixture service in China

in Drugs Outcomes Research and Policies

Jie Cao
Zhou Shu
Jie Li
Dan Wang
Yong-Ning Lyu
Xue-Feng Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1648571

1,576 views

Original Research

Published on 21 Oct 2025

The selective ERβ agonist AC 186 reduces polyinosinic:polycytidylic acid (poly I:C)-induced inflammatory responses in BEAS-2B lung epithelial cells

in Inflammation Pharmacology

Olumayokun A. Olajide
Hope A. Ogiogio

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1706638

1,399 views

Original Research

Published on 21 Oct 2025

Lithium chloride modulates macrophage polarization and enhances bone defect healing in the induced membrane technique by activation of Wnt/β-catenin signaling

in Experimental Pharmacology and Drug Discovery

Yong Qi
Wei Zhang
Ran Zhang
Shuanji Ou
Changpeng Xu
Yang Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1621639

1,494 views

Original Research

Published on 21 Oct 2025

Effectiveness and safety of esketamine in laparoscopic surgery patients: a systematic review and meta-analysis of randomized controlled trials

in Translational Pharmacology

Shuhui Wang
Wei Hao
Hao Fan
Jiasheng Wu
Lifang Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1663348

1,906 views

Original Research

Published on 21 Oct 2025

Immune checkpoint blockers plus chemotherapy as the first-line treatment for advanced or metastatic squamous non-small-cell lung carcinoma: a network meta-analysis and economic evaluation

in Drugs Outcomes Research and Policies

Yitian Lang
Jie Yang
Weican Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1669965

1,623 views

29,570 articles

articles

Diabetes mellitus-driven pulmonary injury: multidimensional mechanisms linking metabolic dysregulation to gut-lung axis and promising therapies

Anti-convulsant efficacy of long-acting injectable cannabidiol formulation (IVL5005) in the pentylenetetrazol-induced convulsions, with pharmacokinetic characterization

Modulatory efficacy of bone metabolism and safety of denosumab versus zoledronic acid in the treatment of bone and joint osteoporosis in elderly men

Circadian rhythm in mycotoxin-induced immunotoxicity: an emerging regulatory axis?

Implementation and impact analysis of a clinical pharmacy ambulatory: a two-year experience

Development and validation of a UHPLC-QqQ-MS/MS method for simultaneous determination of fifteen major components from Oroxyli seed extract in rat plasma and its application in the pharmacokinetic study

Integrated chemometric evaluation of morphological traits, chemical composition, and hepatotoxicity of Polygonum multiflorum

Adherence, satisfaction, and quality of life in Wilson disease patients after switching to trientine tetrahydrochloride: observational data from a dual cohort study

Tongxinluo capsule for acute myocardial infarction: a systematic review and meta-analysis

Effect of formononetin on progressive pulmonary pathologies: multitarget mechanisms and therapeutic prospects

Correction: Therapeutic effects of Eucommia ulmoides extract on osteoporosis rat models: a systematic review and meta-analysis

Correction: Targeting digestive system cancers with isoliquiritigenin: a comprehensive review of antitumor mechanisms

CU06-1004 inhibits the progression of chronic colitis and colitis-associated colorectal cancer by suppressing inflammation

Correction: Psychiatric adverse events associated with infliximab: a cohort study from the French nationwide discharge abstract database

Case Report: Extended survival in KRAS-G12V NSCLC with leptomeningeal metastasis through integrated intrathecal chemotherapy and systemic therapies

The chemical structure, pharmacological activity, and clinical progress of Gentianae Radix et Rhizoma

Comparative efficacy and safety of Xuebijing injection as adjuvant therapy in sepsis-associated acute kidney injury: a systematic review and meta-analysis

Anti-obesity effects of Wumeishanzhayin: an integrated lipidomics and transcriptomics study

NeuproGemp, a polyphenol-rich botanical formula, ameliorates Alzheimer’s-like pathology in APP/PS1 mice via inhibition of human glutaminyl cyclase

Investigation and analysis on the charging status and standard of pharmacy intravenous admixture service in China

The selective ERβ agonist AC 186 reduces polyinosinic:polycytidylic acid (poly I:C)-induced inflammatory responses in BEAS-2B lung epithelial cells

Lithium chloride modulates macrophage polarization and enhances bone defect healing in the induced membrane technique by activation of Wnt/β-catenin signaling

Effectiveness and safety of esketamine in laparoscopic surgery patients: a systematic review and meta-analysis of randomized controlled trials

Immune checkpoint blockers plus chemotherapy as the first-line treatment for advanced or metastatic squamous non-small-cell lung carcinoma: a network meta-analysis and economic evaluation