Frontiers in Pharmacology

Original Research

Published on 06 Feb 2026

7-Dehydrocholesterol attenuates osteoarthritis by synergistically inhibiting oxidative stress, inflammation, and ferroptosis in macrophages

in Inflammation Pharmacology

Wenchao Zhang
Mengru Hua
Xinyu Zhao
Guangxin Sun
Yuheng Pan
Le Miao
Xuzhuo Chen
Shanyong Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1760112

523 views

Original Research

Published on 06 Feb 2026

CYP2C19 genotype-guided escalation to ticagrelor vs. clopidogrel in secondary stroke prevention: a retrospective cohort study

in Pharmacogenetics and Pharmacogenomics

Sun Haidong
Deng Min
Yu Hong
Yang Jing

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1747121

552 views

Original Research

Published on 06 Feb 2026

A novel pyrrolidine-chalcone derivative exhibits synergistic anti-cervical cancer activity by dual-targeting MDM2-p53 axis and ferroptosis pathway

in Experimental Pharmacology and Drug Discovery

Hainimu Xiamuxi
XinYi Deng
Mourboul Ablise
Tong Yan
Madina Imam
Yu Wang
MingHui Zu
Wutiekuer Wumaier

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1715712

447 views

Systematic Review

Published on 06 Feb 2026

Differential cardiovascular benefits of SGLT2 inhibitors, sacubitril/valsartan, omecamtiv mecarbil, and vericiguat across heart failure phenotypes: a systematic review and meta-analysis

in Drugs Outcomes Research and Policies

Meng Wang
Zhihong Zuo
Ting Wu
Zijing Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1644757

534 views

Mini Review

Published on 06 Feb 2026

Heart failure induced by cancer therapies: focus on targeted agents, mechanisms, risk prediction, and clinical management

in Pharmacology of Anti-Cancer Drugs

Lifeng Xiao
Xiaoluan Lin
Zhining Yang
Baihan Lin
Renxian Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1766603

422 views

Original Research

Published on 06 Feb 2026

Danggui Niantong granules in the treatment of rheumatoid arthritis - a mechanistic approach using ceRNA networks

in Ethnopharmacology

Yisi Cai
Yanyan Song
Xiaoling Zeng
Gang Liu
Lixia Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1718584

535 views

Original Research

Published on 06 Feb 2026

Therapeutic potential of combination medicinal mushrooms (NevG) in ischemic stroke: correlating motor function, cognitive recovery, and hippocampal integrity in MCAO rats

in Ethnopharmacology

Nur Athirah Azlan
Misya Afiqah Noor Tuah
Nik Nasihah Nik Ramli
Hussin Muhammad
Zolkapli Eshak
Liao Peng
Chen Bo
Yatinesh Kumari
Imran Jazuli
Che Mohd Nasril Che Mohd Nasir

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1698883

784 views

Original Research

Published on 06 Feb 2026

Exploratory analysis of the association between body composition albumin-bound paclitaxel induced peripheral neuropathy

in Pharmacology of Anti-Cancer Drugs

Ying Jiang
Jiayuan Guo
Juan Zhao
Feng Chen
Jixiang Hou
Xiaorong Li
Zhenhao Li
Gaowa Jin
Quanfu Li

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1644444

379 views

Original Research

Accepted on 05 Feb 2026

Relevance and limitations of clinical follow-up in a pharmacokinetics study on direct oral anticoagulants

in Cardiovascular and Smooth Muscle Pharmacology

Jean Terrier
P. Gosselin
Christophe Combescure
P. Fontana
Y. Daali
JL. Reny

Frontiers in Pharmacology

Review

Accepted on 05 Feb 2026

Ciprofol Injection in Patients Receiving Non-Invasive Positive Pressure Ventilation: A Retrospective Study

in Drugs Outcomes Research and Policies

DaLong Zhang
Lan Xiao
Xue Lv
Chenxi Ma
XiaoHan Zhang
Xingguo Niu

Frontiers in Pharmacology

Original Research

Accepted on 05 Feb 2026

Shen-Yuan-Dan Capsule Inhibits METTL3-mediated m6A methylation to Restore Autophagy Homeostasis and Attenuate Post-Myocardial Infarction Heart Failure

in Ethnopharmacology

Shuai-jie Guo
Si-Qi Chen
Chang-xu Xie
Si-nai Li
Hong-Xu Liu
Lei Zhang
Wei-hong Liu
Ming-xue Zhou

Frontiers in Pharmacology

103 views

Review

Accepted on 05 Feb 2026

Bridging Bioactive Metabolites of Phoenix dactylifera L. with Advanced Nanocarrier Technologies for Mucoadhesive Drug Delivery

in Ethnopharmacology

Abdurrahman Helal Ahmed
Avinash Gangurde
Talib Hussain
Arzu Atalay
Onur Bender
Sirajudheen Anwar

Frontiers in Pharmacology

Correction

Accepted on 05 Feb 2026

Correction: Potential role of lactylation in intrinsic immune pathways in lung cancer

in Pharmacology of Anti-Cancer Drugs

Mengdie Huang
Ye Jin
Dandan Zhao
Xingren Liu

Frontiers in Pharmacology

Systematic Review

Accepted on 05 Feb 2026

Pharmacological Effects and Mechanisms of Curcumin in Animal Models of Parkinson's Disease: A Systematic Review and Meta-Analysis

in Ethnopharmacology

Bowen Pang
Qiang Fu
Huihan He
Xiangyu Guo
Ge Yang

Frontiers in Pharmacology

Review

Accepted on 05 Feb 2026

Nanomaterial-Mediated Modulation of Gut Microbiota for Precision Diagnosis and Treatment of Colorectal Cancer: A Comprehensive Review

in Gastrointestinal and Hepatic Pharmacology

Ying Yang
Shihan Feng
Yunqing Cheng
Min Zhang

Frontiers in Pharmacology

113 views

Original Research

Accepted on 05 Feb 2026

Effects of Sleeve Gastrectomy on Rivaroxaban Pharmacokinetics Parameters, Efficacy, and Safety

in Experimental Pharmacology and Drug Discovery

Saeed Alqahtani
Anfal Almutairi
Faten Aldajani
Manar Basudan
Arwa Alzahrani
Maha Alenazi
Emad Alsarhani
Abdulaziz Alsubaie
Alhassan Almaghrabi
Fahad Bamehriz

Frontiers in Pharmacology

185 views

Original Research

Accepted on 05 Feb 2026

Finerenone Is Associated with Pronounced Uric Acid Reduction in Hyperuricemic Diabetic Kidney Disease: A Real-World Analysis

in Renal Pharmacology

Yanm Lin
Jianqing Tian
Bo Liu
Kang Du

Frontiers in Pharmacology

163 views

Correction

Accepted on 05 Feb 2026

Correction: Fatal adverse events associated with PD-L1 inhibitors: A systematic review and meta-analysis

in Drugs Outcomes Research and Policies

Xuewen Wang
Shijie Wu
Yaying Chen
Erqian Shao
Tingting Zhuang
Linbin Lu
Xiong Chen

Frontiers in Pharmacology

Original Research

Accepted on 05 Feb 2026

Thymoquinone Combined with Conventional Antibiotics Against Pandrug-Resistant Staphylococcus aureus: A Pharmacodynamic and Molecular Simulation Strategy to Overcome Bioavailability Limitations

in Inflammation Pharmacology

Adel Attia M. Ahmad
El-Sayed Y.M. El-Naenaeey
Gamal Elmowalid
Tarek Khamis
Touka A. Kandel
Dina Khodeer
Razan Orfali
Marwa Ibrahim Abd El-Hamid

Frontiers in Pharmacology

152 views

Original Research

Accepted on 05 Feb 2026

Evaluation of potential of Revstone ® on gentamicin induced renal toxicity in Wistar Rats: A Comparative Study of Capsule and Syrup Forms

in Experimental Pharmacology and Drug Discovery

Jayshree Shriram Dawane
Priti Dhande
Chandra Dhar Shukla
Aishwarya Dhakne

Frontiers in Pharmacology

Mini Review

Accepted on 05 Feb 2026

Recent Developments in Quercetin Nanomedicine and Application in Osteoarthritis and Rheumatoid Arthritis Rherapy

in Translational Pharmacology

Yuan Zhu
Hongxuan Chen
Yuanling Yi
Fuhui Zhou
Wenzhi Zhou
Shenghui Zhong

Frontiers in Pharmacology

116 views

Review

Published on 05 Feb 2026

Mesenchymal stem cell-derived exosomes in myocardial infarction repair: therapeutic potential and scaffold-based delivery strategies

in Integrative and Regenerative Pharmacology

Vajiheh Azimian Zavareh
Negar Eslampoor
Sanaz Panahi-Alanagh
Latifeh Malekmohammad
Agata Stanek

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1762630

923 views

Editorial

Published on 05 Feb 2026

Editorial: Plant bioactive compounds as modulators of oncogenic signalling pathways in cervical cancer

in Pharmacology of Anti-Cancer Drugs

Pratibha Pandey
Arif Hussain
Fahad Khan

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1788689

367 views

Original Research

Published on 05 Feb 2026

Sacubitril/valsartan mitigates cisplatin-induced liver injury through modulation of oxidative stress, Caspase-3 activity, and RXR-α signaling in experimental rats

in Gastrointestinal and Hepatic Pharmacology

Majed N. Alshammari
Ahmad H. Alhowail
Mohamed S. Abdel-Bakky
Maha A. Aldubayan

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1745023

586 views

29,512 articles

articles

7-Dehydrocholesterol attenuates osteoarthritis by synergistically inhibiting oxidative stress, inflammation, and ferroptosis in macrophages

CYP2C19 genotype-guided escalation to ticagrelor vs. clopidogrel in secondary stroke prevention: a retrospective cohort study

A novel pyrrolidine-chalcone derivative exhibits synergistic anti-cervical cancer activity by dual-targeting MDM2-p53 axis and ferroptosis pathway

Differential cardiovascular benefits of SGLT2 inhibitors, sacubitril/valsartan, omecamtiv mecarbil, and vericiguat across heart failure phenotypes: a systematic review and meta-analysis

Heart failure induced by cancer therapies: focus on targeted agents, mechanisms, risk prediction, and clinical management

Danggui Niantong granules in the treatment of rheumatoid arthritis - a mechanistic approach using ceRNA networks

Therapeutic potential of combination medicinal mushrooms (NevG) in ischemic stroke: correlating motor function, cognitive recovery, and hippocampal integrity in MCAO rats

Exploratory analysis of the association between body composition albumin-bound paclitaxel induced peripheral neuropathy

Relevance and limitations of clinical follow-up in a pharmacokinetics study on direct oral anticoagulants

Ciprofol Injection in Patients Receiving Non-Invasive Positive Pressure Ventilation: A Retrospective Study

Shen-Yuan-Dan Capsule Inhibits METTL3-mediated m6A methylation to Restore Autophagy Homeostasis and Attenuate Post-Myocardial Infarction Heart Failure

Bridging Bioactive Metabolites of Phoenix dactylifera L. with Advanced Nanocarrier Technologies for Mucoadhesive Drug Delivery

Correction: Potential role of lactylation in intrinsic immune pathways in lung cancer

Pharmacological Effects and Mechanisms of Curcumin in Animal Models of Parkinson's Disease: A Systematic Review and Meta-Analysis

Nanomaterial-Mediated Modulation of Gut Microbiota for Precision Diagnosis and Treatment of Colorectal Cancer: A Comprehensive Review

Effects of Sleeve Gastrectomy on Rivaroxaban Pharmacokinetics Parameters, Efficacy, and Safety

Finerenone Is Associated with Pronounced Uric Acid Reduction in Hyperuricemic Diabetic Kidney Disease: A Real-World Analysis

Correction: Fatal adverse events associated with PD-L1 inhibitors: A systematic review and meta-analysis

Thymoquinone Combined with Conventional Antibiotics Against Pandrug-Resistant Staphylococcus aureus: A Pharmacodynamic and Molecular Simulation Strategy to Overcome Bioavailability Limitations

Evaluation of potential of Revstone ® on gentamicin induced renal toxicity in Wistar Rats: A Comparative Study of Capsule and Syrup Forms

Recent Developments in Quercetin Nanomedicine and Application in Osteoarthritis and Rheumatoid Arthritis Rherapy

Mesenchymal stem cell-derived exosomes in myocardial infarction repair: therapeutic potential and scaffold-based delivery strategies

Editorial: Plant bioactive compounds as modulators of oncogenic signalling pathways in cervical cancer

Sacubitril/valsartan mitigates cisplatin-induced liver injury through modulation of oxidative stress, Caspase-3 activity, and RXR-α signaling in experimental rats