Frontiers in Pharmacology

Original Research

Published on 16 Apr 2025

Synthesis of a novel mitochondrial fluorescent probe - killing cancer cells in vitro and in vivo

in Pharmacology of Anti-Cancer Drugs

Xiaowen Yang
Yiting Zhan
Yifei Li
Xinzhuang Shen
Yuqiu Ma
Zongjun Liu
Yipeng Liu
Chengjin Liang
Xiaoyuan Zhang
Yehao Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1543559

300 views

Original Research

Published on 16 Apr 2025

Gui-zhi-fu-ling-wan alleviates bleomycin-induced pulmonary fibrosis through inhibiting epithelial-mesenchymal transition and ferroptosis

in Ethnopharmacology

Zi-Yong Chen
Meng-Meng Ma
Rui Wang
Qing-Qing Zhang
Mei-Ling Xie
Ying-Li Wang
Yong-Xia Guo
Kui Liu
Li-Fang Cao
Feng-Lian He

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1552251

345 views

Review

Published on 16 Apr 2025

Hepatorenal protective effects of essential oils against chemical overexposure induced oxidative damage

in Experimental Pharmacology and Drug Discovery

Faming Jiang
Xiaoyan Huang
Xingying Chen
Yuanhua Xian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1580805

270 views

Systematic Review

Published on 16 Apr 2025

Scoping review of ethnobotanical studies on Piliostigma thonningii (Schumach.) Milne-Redh. in Sub-Saharan Africa

in Ethnopharmacology

Bono Nethathe
Lonia Maanea Ramphinwa
Ananias Selekane Motadi
Frans Koketso Matlakala

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1575548

257 views

Original Research

Published on 16 Apr 2025

The development of a high-throughput acoustic droplet ejection mass-spectrometry assay and a solid-supported membrane (SSM)-based electrophysiological assay to study the pharmacological inhibition of SLC1-A3, -A2 and -A1 in a drug discovery program

in Experimental Pharmacology and Drug Discovery

Yasmin Zuschlag
Antje Pommereau
Jennifer Warkentin
Thomas Licher
Felix Bärenz

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1544682

378 views

Original Research

Published on 16 Apr 2025

Dracaena trifasciata (Prain) Mabb leaf extract protects MIN6 pancreas-derived beta cells against the diabetic toxin streptozotocin: role of the NF-κB pathway

in Ethnopharmacology

Christiaan Warner Hoornenborg
Nur Qomariyah
Herson Antonio González-Ponce
André Petrus Van Beek
Han Moshage
Gertjan Van Dijk

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1485952

591 views

Review

Published on 16 Apr 2025

Emerging roles of exosomes in the diagnosis and treatment of kidney diseases

in Renal Pharmacology

Huanhuan Cao
Zixi Li
Jiajia Ye
Yi Lv
Chun Zhang
Tao Liang
Yumei Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1525314

215 views

Original Research

Published on 16 Apr 2025

Association of long-term use of dipeptidyl peptidase-4 inhibitors with the risk of diabetic retinopathy in patients with diabetes mellitus: a real-world evidence study

in Pharmacoepidemiology

Yu-Ching Li
Yu-Hsiang Kuan
Yih Yang
Shuo-Yan Gau
Kun-Yu Su
Tung-Han Tsai
Kuang-Hua Huang
Chien-Ying Lee

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1518545

353 views

Review

Published on 16 Apr 2025

Mechanism underlying the involvement of CXCR4/CXCL12 in diabetic wound healing and prospects for responsive hydrogel-loaded CXCR4 formulations

in Inflammation Pharmacology

Lingli Wang
Fengsong Nie
Zhaoyu Lu
Yang Chong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561112

262 views

Original Research

Published on 16 Apr 2025

Acute hypobaric hypoxia attenuates the anti-fatigue effects of pitolisant by downregulating the expression of organic cation transporter 1 and P-glycoprotein

in Drug Metabolism and Transport

Gang Zhao
Yajuan Li
Mengyuan Liu
Wei Chang
Hui Shen
Junhui Xue
Fengzhou Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1564174

260 views

Review

Published on 16 Apr 2025

The role of transcytosis in the blood-retina barrier: from pathophysiological functions to drug delivery

in Drug Metabolism and Transport

Chun-Lin Zhang
Jing-Jie Ma
Xiang Li
Hai-Qing Yan
Yong-Kun Gui
Zhi-Xin Yan
Ming-Feng You
Ping Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1565382

252 views

Systematic Review

Published on 16 Apr 2025

The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis

in Obstetric and Pediatric Pharmacology

Shaohong Lin
Ruming Ye
Guanhong Wu
Lixia Wu
Ying Lin
Dan Li
Namei Xie
Huiyue Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1554438

247 views

Review

Published on 16 Apr 2025

Efficacy of Xuebijing injection on pulmonary ventilation improvement in acute pancreatitis: a systematic review and meta-analysis

in Ethnopharmacology

Yuling Bin
Rumei Peng
Yaqian Lee
Zhijie Lee
Yang Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1549419

171 views

Original Research

Published on 16 Apr 2025

Inhibition of colorectal cancer cell growth by downregulation of M2-PK and reduction of aerobic glycolysis by clove active ingredients

in Gastrointestinal and Hepatic Pharmacology

Lin Liu
Gang Xing
Xiaoyi Guo
Hui Chen
Jian Li
Jian Wang
Yaling Li
Gang Liang
Minghua Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1552486

378 views

Original Research

Published on 16 Apr 2025

A real-world pharmacovigilance study of efgartigimod alfa in the FDA adverse event reporting system database

in Pharmacoepidemiology

Yunlin Yang
Jinfeng Liu
Wei Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1510992

779 views

Review

Published on 16 Apr 2025

Ginsenoside Rg1 in Parkinson’s disease: from basic research to clinical applications

in Neuropharmacology

Qianyan Wang
Lei Wei
Guanghui Chen
Qiang Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1490480

203 views