Frontiers in Pharmacology

Original Research

Published on 05 Feb 2026

Evaluation of Andrographis paniculata in a mouse model of influenza A viral infection using oral administration and a translationally relevant dose

in Ethnopharmacology

Kashif Shamim
Grace C. Burnett
Jin Zhang
Nessma H. Ahmed
Shabana I. Khan
Amar G. Chittiboyina
Ikhlas A. Khan
Gailen D. Marshall
John T. Bates
Nirmal D. Pugh

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1749384

674 views

Original Research

Published on 05 Feb 2026

Seawater pearl hydrolysate alleviates perimenopausal syndrome by modulating hypothalamic and uterine ERα/MAPK/CREB signaling in ovariectomized rats

in Ethnopharmacology

Yasheng Deng
Tianwei Liang
Hui Huang
Siyin Han
Yanping Fan
Jiang Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1749728

381 views

Original Research

Published on 05 Feb 2026

Comparative analysis of bioactivities of leaf extracts from wild plant species Verbascum sinuatum, Amaranthus spinosus, Carduus getulus, and Heterotheca subaxillaris collected in Gaza Strip, Palestine

in Experimental Pharmacology and Drug Discovery

Mohamad Abou Auda
Mohammed Eleyan
Tarek Atia
Hader I. Sakr

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1753226

712 views

Original Research

Published on 05 Feb 2026

Combined azelastine fluticasone nasal spray versus fluticasone propionate nasal spray in postoperative management of central compartment atopic disease (CCAD)

in Drugs Outcomes Research and Policies

Samy Elwany
Ahmed Aly Ibrahim
Mona Elwany
Nihad Tousson-Abouelazm
Amr Kholief

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1732886

544 views

Editorial

Accepted on 04 Feb 2026

Editorial: Advancing Antibiotic Candidates for Eradication of Persistent Bacterial Infections

in Translational Pharmacology

Laurent Bekale
Jessica Amber Jennings
Xilin Zhao

Frontiers in Pharmacology

209 views

Original Research

Accepted on 04 Feb 2026

Comparative Safety Profiles of Risankizumab versus Guselkumab: A Pharmacovigilance Study Based on the FAERS Database

in Pharmacoepidemiology

Shiyi Wang
Yongyi Xu
Hangjuan Lin
Xudong Zhang
Jing Ding
Honggang Jiang
Yihong Fan
Changbo Sun

Frontiers in Pharmacology

275 views

Review

Accepted on 04 Feb 2026

Selective phosphoinositide 3-kinase inhibitors and implication in diabetic retinopathy as pharmacological tools

in Neuropharmacology

Carmela Bonaccorso
Francesca Lazzara
Isabel La Rosa
Cristina Munzone
Alessandro Grasso
Chiara Bianca Maria Platania
Claudio Bucolo

Frontiers in Pharmacology

193 views

Original Research

Accepted on 04 Feb 2026

Prediction of Site-Specific Drug Deposition via Dry Powder Inhaler using Non-Invasive Real-Time Particle Emission Signal Monitoring System

in Respiratory Pharmacology

Sakiko Hatazoe
Daiki Hira
Tetsuri Kondo
Yuki Shigetsura
Natsuki Imayoshi
Yurie Katsube
Keiko Ikuta
Yuki Kunitsu
Keisuke Umemura
Satoshi Hamada

Frontiers in Pharmacology

214 views

Correction

Published on 04 Feb 2026

Correction: Ramulus mori (Sangzhi) alkaloids improve intestinal oxidative damage and inflammation in DHEA-induced polycystic ovary syndrome rats via gut microbiota and metabolite modulation

in Experimental Pharmacology and Drug Discovery

Yanping Wang
Xianmei Jiang
Shuyi Wu
Qiaohui Wang
Dan Zuo
Biao Huang
Li Jian
Yu Yang
Yong Cai
Xingjian Wen

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1794631

317 views

Systematic Review

Published on 04 Feb 2026

Estimated preventive dose of racemic ketamine for shivering and pruritus prophylaxis in cesarean delivery: a Monte Carlo simulation guided network meta-analysis

in Obstetric and Pediatric Pharmacology

Wei-Long Wang
Jin Zhou
Yi Cai
Min-Zhu Zheng
Kai-Yu Chen
Ying Hu
Xin Men
Jian-Liang Sun
Xu Qiu
Zhen-Feng Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1751842

696 views

Mini Review

Published on 04 Feb 2026

Immunotherapy-related cardiovascular toxicity: from mechanisms to management

in Pharmacology of Anti-Cancer Drugs

Lifeng Xiao
Weitong Liu
Yanchen Ji
Qiufeng Li
Junqing Pan
Renxian Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1762011

453 views

Original Research

Published on 04 Feb 2026

PLA-THF-PEG nanoparticles Co-encapsulating AV3 and KH3 for synergistic pancreatic cancer therapy via stromal remodeling and metabolic inhibition

in Experimental Pharmacology and Drug Discovery

Xiaorong Liu
Yuanmin Hu
Jiaqi Yu
Yuzhe Xue
Xuesong He
Fenfen Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1723694

478 views

Original Research

Published on 04 Feb 2026

Association of serum methylglyoxal with endothelial dysfunction in patients with type 2 diabetes

in Cardiovascular and Smooth Muscle Pharmacology

Shanshan Yu
Xinyan Jin
Yuanying Xu
Zhao Liu
Jun Lu
Jie Gao
Wenjun Sha
Tao Lei

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1773149

403 views

Original Research

Accepted on 03 Feb 2026

A thermosensitive hydrogel encapsulating 2-DG alleviates periodontitis by inhibiting glycolysis and effector response of Th17 cells

in Inflammation Pharmacology

Ruowen Zhao
Jia Li
JunHao Yin
Jiabao Xu
Changyu Chen
Jiayu Yan
Siyi Chen
Jiayao Fu
Junhua Wu

Frontiers in Pharmacology

221 views

Original Research

Accepted on 03 Feb 2026

Discovery of Potent Bisindole-based Pyrazolopyridine Derivatives as Topoisomerase Inhibitors: DNA Damage Induction and Synergistic Antileukemic Activity

in Pharmacology of Anti-Cancer Drugs

Wagdy Mohamed Eldehna
Haytham O. Tawfik
Denisa Veselá
Miroslav Peřina
Ahmed Thabet Negmeldin
Zainab M. Elsayed
Taghreed A Majrashi
Veronika Vojáčková
Mostafa M. Elbadawi
Moataz Ahmed Shaldam

Frontiers in Pharmacology

292 views

Original Research

Accepted on 03 Feb 2026

Sertraline safety in adolescents experiencing a depressive episode during first 3 weeks: added anxiolytic matters more than CYP2C19 polymorphisms

in Pharmacogenetics and Pharmacogenomics

Dmitriy V. Ivashchenko
Vitaliy V. Sobur
Sergey V. Grass
Anna Y. Basova
Rimma V. Kondratieva
Eugenia N. Shagovenko
Yulia V. Chernetsova
Svetlana N. Tuchkova
Ivan N. Korsakov
Sergey I. Markov

Frontiers in Pharmacology

140 views

Review

Accepted on 03 Feb 2026

Oleanolic acid and its derivatives in breast cancer therapy: mechanistic insights, structural modifications, and novel delivery strategies

in Pharmacology of Anti-Cancer Drugs

Xiaofei Hu
Yuting Qin

Frontiers in Pharmacology

152 views

Review

Accepted on 03 Feb 2026

Efficacy and Safety of Tyrosine Kinase Inhibitors in Advanced Hepatocellular Carcinoma Patients with Child-Pugh A and B Cirrhosis: A Meta-Analysis

in Pharmacology of Anti-Cancer Drugs

Xionglin Liu
Jindu Li
MinJun Li
Bangde Xiang

Frontiers in Pharmacology

Original Research

Accepted on 03 Feb 2026

AP39 Alleviates HHCY-Induced Myocardial Remodeling by Regulating FUNDC1-Mediated Mitochondrial Dynamics via S-Sulfhydration of NEDD8/CUL4B

in Cardiovascular and Smooth Muscle Pharmacology

Ya Ling Li
Jianghe Jiang
chenlong luo
Yan Shi
Ting Yang
Shengquan Liu
Chun Chu
Jun Yang

Frontiers in Pharmacology

132 views

Original Research

Accepted on 03 Feb 2026

Comparative Efficacy of Intravenous, Topical, and Combined Tranexamic Acid in Elderly Patients with Intertrochanteric Fractures Undergoing Intramedullary Nail Fixation: A Multicenter Cohort Study

in Pharmacoepidemiology

Qiushi Bai
Xiao Chang
Yuewang Li
YongMing Yang
Hongbo Zhang
Kunyu Ji
Xiongfei Zou
Baozhong Zhang

Frontiers in Pharmacology

Review

Accepted on 03 Feb 2026

Preclinical Approaches to Studying Liver and Kidney Fibrosis: Models and Methodologies

in Gastrointestinal and Hepatic Pharmacology

Abhilasha Tiwari
Shivam Singh
Rajesh Kumar Sharma
Sandeep Kumar

Frontiers in Pharmacology

141 views

Editorial

Accepted on 03 Feb 2026

Exploiting Non-Oncogene Addiction to Overcoming Drug Resistance in Metastatic Neoplasias

in Experimental Pharmacology and Drug Discovery

Albrecht Reichle
Dennis Christoph Harrer
Florian Lüke
Tobias Pukrop
Lina Ghibelli
Daniel Heudobler

Frontiers in Pharmacology

Original Research

Accepted on 03 Feb 2026

Ketoprofen-Loaded Quatsomes as a Smart Repurposed Antifungal Therapy for Vaginal Infections: Formulation, Characterization, and Microbiological Evaluation

in Experimental Pharmacology and Drug Discovery

Alaa Emad Eldeeb
Diana E. Aziza
Mariam Hassan
Osama Saher
Sadek Ahmed

Frontiers in Pharmacology

119 views

Original Research

Accepted on 03 Feb 2026

Multi-Target Computational Pipeline for Discovery of Pan-Influenza Neuraminidase Inhibitors

in Experimental Pharmacology and Drug Discovery

Smbat Gevorgyan
Marusya Ayvazyan
Levon Kharatyan
Anastasiya Shavina
Narek Abelyan
Hamlet Khachatryan
Hovakim Zakaryan

Frontiers in Pharmacology

100 views