Frontiers in Pharmacology | Cardiovascular and Smooth Muscle Pharmacology

Original Research

Accepted on 31 Dec 2025

Differential Musculoskeletal Outcome Reporting in Patients Receiving Bempedoic Acid or Atorvastatin: A Disproportionality Analysis Using the EudraVigilance Database

in Cardiovascular and Smooth Muscle Pharmacology

Gianluca Gazzaniga
Antonio Romio
Chiara Galuppi
Elena Gentile
Filomena Valentino
Luca De Toni
Michela Foschiatti
Michele Gringeri
Stefano D'Onghia
Danilo Menichelli

Frontiers in Pharmacology

Original Research

Accepted on 31 Dec 2025

Early treatment of Nootkatone Prevents Pressure Overload-induced Ventricular Remodeling and Heart Failure

in Cardiovascular and Smooth Muscle Pharmacology

Zhongyuan Liu
Zixin Zhou
Wenjing Yuan
JiaJin Li
Jie Tian
Mi Li
Junjun Quan

Frontiers in Pharmacology

Original Research

Accepted on 29 Dec 2025

Inflammatory and chemotactic signals of the brainstem solitary tract mediate the morphine exacerbation of impaired reflex chronotropism in septic rats

in Cardiovascular and Smooth Muscle Pharmacology

Mohamed Abdelnaby
Marwa Y Sallam
Mai M Helmy
Hanan M El-Gowelli
Mahmoud M El-Mas

Frontiers in Pharmacology

Brief Research Report

Accepted on 26 Dec 2025

Subclavian Artery Stenosis in Hemodialysis Patients: A Case Series and Review of the Literature

in Cardiovascular and Smooth Muscle Pharmacology

Wenshen Pu
Jingjie Yang
Qiquan Lai
Yu Zhou
Bo Tu
Bingjie Wang
Ziming Wan

Frontiers in Pharmacology

Original Research

Accepted on 24 Dec 2025

Clusterin protect against HFpEF by inhibiting UCHL1 mediated NLRP3 deubiquitylation and the inflammasome activation

in Cardiovascular and Smooth Muscle Pharmacology

Jiangling Yu
Xiaoxu Kang
Rui Chang
Cheng Zhang
Song Yang
Lang Chen
Xinbo Wang
Bing Hu
Zixuan Wang
Lili Gong

Frontiers in Pharmacology

Review

Accepted on 23 Dec 2025

Vulnerable Plaques in Atherosclerosis: Focus on Angiogenesis-Associated Phenotypic Crosstalk

in Cardiovascular and Smooth Muscle Pharmacology

Xin-zheng Hou
Yingtian Yang
Jian-Ming Yao

Frontiers in Pharmacology

115 views

Mini Review

Published on 19 Dec 2025

Research progress in the prevention and treatment of radiation-induced heart disease

in Cardiovascular and Smooth Muscle Pharmacology

Ye Sun
Chenyi Zheng
Lin Li
Shenglin Zhang
Jiajuan Guo
Jincheng Lv

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1745302

584 views

Original Research

Published on 18 Dec 2025

Differential effects of PCSK9 inhibitors and statins on plasma ceramides in coronary artery disease

in Cardiovascular and Smooth Muscle Pharmacology

Liang Zhang
Yaodong Ding
Yong Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1726925

458 views

Hypothesis and Theory

Accepted on 17 Dec 2025

X-inactive specific transcript (XIST) can determine sex differences in cardiovascular drug responses: focus on RNA therapeutics

in Cardiovascular and Smooth Muscle Pharmacology

Timur O Yarovinsky
Vinod S Ramgolam
Iva Knezevic
Nina S Stachenfeld
Jeffrey R Bender

Frontiers in Pharmacology

213 views

Original Research

Accepted on 16 Dec 2025

Levocarnitine improves cardiac energy metabolic remodeling in myocarditis mice

in Cardiovascular and Smooth Muscle Pharmacology

Shutong Yang
Xiaoou Li
zhenpeng Lu
Xiang Xu
Zuzhen Guo
Bing He

Frontiers in Pharmacology

Original Research

Accepted on 16 Dec 2025

Dual Therapy with Allicin and Metformin Provides Superior Cardioprotection Against Doxorubicin-Induced Cardiotoxicity in Rats Compared to Monotherapy

in Cardiovascular and Smooth Muscle Pharmacology

Hassan Mohammed
Mohammed Mojamel
Afif Al-Nabehi

Frontiers in Pharmacology

178 views

Review

Published on 16 Dec 2025

Recent advances in mineralocorticoid receptor antagonists for heart failure with preserved ejection fraction: focus on finerenone in the era of sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptor agonists

in Cardiovascular and Smooth Muscle Pharmacology

Tian-Yu Wang
Lei Zhang
Huan-Yi Wang
Fen-Fen Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1725782

640 views

Original Research

Published on 16 Dec 2025

O-GlcNAcylation of eNOS in high-salt-induced thoracic aorta endothelial dysfunction in mice

in Cardiovascular and Smooth Muscle Pharmacology

Chang Li
Liuming Gao
Yi Ling
Zhan Lv

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1730447

499 views

Review

Accepted on 15 Dec 2025

Advancements in Research on the Cardiovascular Toxicity caused by TEC Family Kinases Inhibitors

in Cardiovascular and Smooth Muscle Pharmacology

Yi Zhang
Huangxi Fu
Xingchen Kang
Zixuan Qiu
Hao Yan
Qiaojun He
Bo Yang
Zhifei Xu
Peihua Luo

Frontiers in Pharmacology

134 views

Review

Accepted on 11 Dec 2025

Cardioprotection for radiation-induced heart disease in breast cancer patients

in Cardiovascular and Smooth Muscle Pharmacology

Sabina Mędrek
Kasper Rolek
Jakub Homotnik
Sebastian Szmit

Frontiers in Pharmacology

104 views

Original Research

Accepted on 11 Dec 2025

TLR4 Modulates Simvastatin's Impact on HDL Cholesterol and Glycemic Control

in Cardiovascular and Smooth Muscle Pharmacology

Xiao Tian
Peixiang Zhang

Frontiers in Pharmacology

168 views

Correction

Published on 11 Dec 2025

Correction: Terminal complement inhibition in atypical haemolytic uremic syndrome: a single-centre experience

in Cardiovascular and Smooth Muscle Pharmacology

Valentin D. Mocanu
Bogdan M. Sorohan
Elena G. Micu
Sonia Bălănică
Bogdan Obrişcă
Roxana A. Jurubiță
Camelia A. Achim
Adrian C. Lungu
Cristina S. Căpuşă
Gabriel Mircescu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1760223

369 views

Original Research

Published on 11 Dec 2025

Ensemble learning approach with explainable AI for improved heart disease prediction

in Cardiovascular and Smooth Muscle Pharmacology

Ayomide Adekoya
Faisal Saeed
Wad Ghaban
Sultan Noman Qasem

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1654681

568 views

Review

Accepted on 10 Dec 2025

Comparative Efficacy of Pharmacological Agents on Abdominal Aortic Aneurysm Growth Rate: A Systematic Review and Network Meta-Analysis

in Cardiovascular and Smooth Muscle Pharmacology

Cheng Wen
Lilong Li
Bo Wang
Linyang Xie
Huaping Wu

Frontiers in Pharmacology

132 views

Original Research

Accepted on 10 Dec 2025

In vitro exploration of drug-induced thrombotic microangiopathies: clues of diverse endothelial activation pathways respective to interferon-β1a, ciclosporin A, and gemcitabine exposure

in Cardiovascular and Smooth Muscle Pharmacology

Edouard Cubilier
Maxime Taghavi
Eric De Prez
Lucas Jacobs
Sébastien Sinaeve
Joelle Nortier
Marie-Hélène Antoine

Frontiers in Pharmacology

148 views

Mini Review

Accepted on 09 Dec 2025

Tumor-like Characteristics of Vascular Smooth Muscle Cells in Atherosclerosis

in Cardiovascular and Smooth Muscle Pharmacology

Xiangchun Li
Yuyan Deng

Frontiers in Pharmacology

180 views

Review

Accepted on 09 Dec 2025

Targeting CD73 and correcting adenosinergic signaling in critically ill patients

in Cardiovascular and Smooth Muscle Pharmacology

Justin Lunderberg
Alexander James Spicer
Jessica Cassavaugh
Juho Jalkanen
George Hasko
Simon C Robson

Frontiers in Pharmacology

140 views

Original Research

Published on 09 Dec 2025

Impact of different doses of rivaroxaban on clinical outcomes in elderly patients with non-valvular atrial fibrillation: a real-world study

in Cardiovascular and Smooth Muscle Pharmacology

Juan Yu
Zufeng Zhang
Qingru Yuan
Haobing Hu
Huimin Li
Meifang Huang
Youlin Mao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1714318

588 views

Original Research

Accepted on 04 Dec 2025

β-sitosterol ameliorates myocardial infarction injury via modulating the NF-κB and necroptosis signaling pathways

in Cardiovascular and Smooth Muscle Pharmacology

Jia-jia Xu
Min-wei Chen
Long-zhen Lai
Di Xiao
Shu-yan Jiang
Jun-xin Lin
Zheng-hao Zhang
Zhonggui Shan

Frontiers in Pharmacology

182 views

1,408 articles

articles

Differential Musculoskeletal Outcome Reporting in Patients Receiving Bempedoic Acid or Atorvastatin: A Disproportionality Analysis Using the EudraVigilance Database

Early treatment of Nootkatone Prevents Pressure Overload-induced Ventricular Remodeling and Heart Failure

Inflammatory and chemotactic signals of the brainstem solitary tract mediate the morphine exacerbation of impaired reflex chronotropism in septic rats

Subclavian Artery Stenosis in Hemodialysis Patients: A Case Series and Review of the Literature

Clusterin protect against HFpEF by inhibiting UCHL1 mediated NLRP3 deubiquitylation and the inflammasome activation

Vulnerable Plaques in Atherosclerosis: Focus on Angiogenesis-Associated Phenotypic Crosstalk

Research progress in the prevention and treatment of radiation-induced heart disease

Differential effects of PCSK9 inhibitors and statins on plasma ceramides in coronary artery disease

X-inactive specific transcript (XIST) can determine sex differences in cardiovascular drug responses: focus on RNA therapeutics

Levocarnitine improves cardiac energy metabolic remodeling in myocarditis mice

Dual Therapy with Allicin and Metformin Provides Superior Cardioprotection Against Doxorubicin-Induced Cardiotoxicity in Rats Compared to Monotherapy

Recent advances in mineralocorticoid receptor antagonists for heart failure with preserved ejection fraction: focus on finerenone in the era of sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptor agonists

O-GlcNAcylation of eNOS in high-salt-induced thoracic aorta endothelial dysfunction in mice

Advancements in Research on the Cardiovascular Toxicity caused by TEC Family Kinases Inhibitors

Cardioprotection for radiation-induced heart disease in breast cancer patients

TLR4 Modulates Simvastatin's Impact on HDL Cholesterol and Glycemic Control

Correction: Terminal complement inhibition in atypical haemolytic uremic syndrome: a single-centre experience

Ensemble learning approach with explainable AI for improved heart disease prediction

Comparative Efficacy of Pharmacological Agents on Abdominal Aortic Aneurysm Growth Rate: A Systematic Review and Network Meta-Analysis

In vitro exploration of drug-induced thrombotic microangiopathies: clues of diverse endothelial activation pathways respective to interferon-β1a, ciclosporin A, and gemcitabine exposure

Tumor-like Characteristics of Vascular Smooth Muscle Cells in Atherosclerosis

Targeting CD73 and correcting adenosinergic signaling in critically ill patients

Impact of different doses of rivaroxaban on clinical outcomes in elderly patients with non-valvular atrial fibrillation: a real-world study

β-sitosterol ameliorates myocardial infarction injury via modulating the NF-κB and necroptosis signaling pathways