Frontiers in Pharmacology | Cardiovascular and Smooth Muscle Pharmacology

Original Research

Published on 12 Sep 2024

Inhibition of the RIP3/MLKL/TRPM7 necroptotic pathway ameliorates diabetes mellitus-induced erectile dysfunction by reducing cell death, fibrosis, and inflammation

in Cardiovascular and Smooth Muscle Pharmacology

Lipan Niu
Pei Yang
Bingbing Zhu
Xiufang Jin
Chengxia Yang
Xijia Zhang
Yulian Liu
Rui Zhang
Fengxia Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1436013

3,072 views
2 citations

Review

Published on 06 Sep 2024

Role of naringin in the treatment of atherosclerosis

in Cardiovascular and Smooth Muscle Pharmacology

Yan Lu
De-Hong Li
Ji-Mei Xu
Sheng Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1451445

3,993 views
6 citations

Original Research

Published on 30 Aug 2024

Generation of a medicine food homology formula and its likely mechanism in treatment of microvascular angina

in Cardiovascular and Smooth Muscle Pharmacology

Zhidie Jin
Mingwang Liu
Beili Xie
Wei Wen
Yuxin Yan
Yangfang Zhang
Haohao Li
ZhengYu Shen
Lulian Jiang
Mengjie Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1404874

4,837 views
2 citations

Original Research

Published on 28 Aug 2024

Effect of different single and combined antihypertensive drug regimens on the mortality of critical care patients

in Cardiovascular and Smooth Muscle Pharmacology

Yipeng Fang
Xianxi Huang
Junyu Shi
Chunhong Ren
Xin Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1385397

2,562 views
1 citation

Review

Published on 28 Aug 2024

Tirzepatide’s innovative applications in the management of type 2 diabetes and its future prospects in cardiovascular health

in Cardiovascular and Smooth Muscle Pharmacology

Jingqi Yang
Yuncheng Gu
Huaigang Chen
Hong Wang
Lang Hong
Bin Li
Liu Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1453825

11,299 views
9 citations

Editorial

Published on 21 Aug 2024

Editorial: Design of novel inhibitors for ischemia/reperfusion injury targeting ferroptosis

in Cardiovascular and Smooth Muscle Pharmacology

Xuyang Wang
Qiming Deng
Jingchen Hou
Kalyan Kumar Pasunooti
Kevin Bermea
Kai Li
Genaro A. Ramirez-Correa
Xiaomei Yang
Jianbo Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1475526

1,636 views
2 citations

Review

Published on 20 Aug 2024

Regulation mechanism of microRNAs in cardiac cells-derived exosomes in cell crosstalk

in Cardiovascular and Smooth Muscle Pharmacology

Shanshan Lin
Yuanjian Yang
Zhou Zhou
Wen Li
Xianliang Wang
Yu Liu
Yingfei Bi
Jingyuan Mao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1399850

3,006 views
1 citation

Original Research

Published on 15 Aug 2024

Suppression of NLRP3 inflammasome orchestrates the protective efficacy of tiron against isoprenaline-induced myocardial injury

in Cardiovascular and Smooth Muscle Pharmacology

Doaa Abdelrahaman
Ola A. Habotta
Ehab S. Taher
Eman S. El-Ashry
Iman Ibrahim
Ahmed Abdeen
Ateya M. Ibrahim
Reham M. Ibrahim
Hala Anwer
Ostan Mihaela

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1379908

2,492 views
6 citations

Review

Published on 15 Aug 2024

Advancements in understanding cardiotoxicity of EGFR- TKIs in non-small cell lung cancer treatment and beyond

in Cardiovascular and Smooth Muscle Pharmacology

Xin Li
Yongping Lin
Song Lin
Jiayi Huang
Zhongbao Ruan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1404692

4,518 views
12 citations

Original Research

Published on 13 Aug 2024

Puerarin attenuates myocardial ischemic injury and endoplasmic reticulum stress by upregulating the Mzb1 signal pathway

in Cardiovascular and Smooth Muscle Pharmacology

Jiaojiao Xue
Haolin Ren
Qi Zhang
Jing Gu
Qian Xu
Jiaxi Sun
Lu Zhang
Ming-Sheng Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1442831

5,288 views
5 citations

Original Research

Published on 13 Aug 2024

Impact of β-blockers on in-hospital mortality in patients with heart failure: a retrospective propensity-score matched analysis based on MIMIC-IV database

in Cardiovascular and Smooth Muscle Pharmacology

Xin Wang
Yuzhu Zhang
Jiangling Xia
Hongyu Xu
Lu Zhang
Nianhai Feng
Xiaona An

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1448015

3,350 views
1 citation

Editorial

Published on 12 Aug 2024

Editorial: Diabetes and cardiovascular disease: new therapeutic interventions

in Cardiovascular and Smooth Muscle Pharmacology

Maria Consiglia Trotta
Michele D’Amico
Ludwig T. Weckbach
Anca Hermenean
Bartolo Ferraro

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1472636

1,682 views

Original Research

Published on 12 Aug 2024

Association between acetaminophen administration and outcomes in critically ill patients with gout and hypertension

in Cardiovascular and Smooth Muscle Pharmacology

Xiao-Qing Yi
Bo Xie
Yuan Hu
Tian-Jiao Gong
Min Chen
Xiao-Jiao Cui

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1445975

3,355 views
3 citations

Original Research

Published on 12 Aug 2024

11-Hydroxyeicosatetraenoics induces cellular hypertrophy in an enantioselective manner

in Cardiovascular and Smooth Muscle Pharmacology

Sara A. Helal
Ahmed A. El-Sherbeni
Ayman O. S. El-Kadi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1438567

2,054 views
3 citations

Original Research

Published on 08 Aug 2024

Reliability of Metformin’s protective effects against doxorubicin-induced cardiotoxicity: a meta-analysis of animal studies

in Cardiovascular and Smooth Muscle Pharmacology

Ming-Li Sun
Wei Chen
Xing-He Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1435866

2,475 views
6 citations

Review

Published on 08 Aug 2024

Time-restricted eating, the clock ticking behind the scenes

in Cardiovascular and Smooth Muscle Pharmacology

Aleix Ribas-Latre
Sonia Fernández-Veledo
Joan Vendrell

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1428601

11,480 views
8 citations

Original Research

Published on 07 Aug 2024

Alchemilla vulgaris modulates isoproterenol-induced cardiotoxicity: interplay of oxidative stress, inflammation, autophagy, and apoptosis

in Cardiovascular and Smooth Muscle Pharmacology

Nuha Anajirih
Ahmed Abdeen
Ehab S. Taher
Afaf Abdelkader
Hoda A. Abd-Ellatieff
Mahmoud S. Gewaily
Nashwa E. Ahmed
Rasha H. Al-Serwi
Safwa M. Sorour
Heba M. Abdelkareem

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1394557

4,072 views
4 citations

Original Research

Published on 07 Aug 2024

Comprehensive mendelian randomization reveals atrial fibrillation-breast cancer relationship and explores common druggable targets

in Cardiovascular and Smooth Muscle Pharmacology

Fenglin Qi
Lunzhe Yang
Guanglei Chang
Xiangbin Wang
Guanghong Tao
Hua Xiao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1435545

4,605 views
1 citation

Original Research

Published on 06 Aug 2024

KIF11 promotes vascular smooth muscle cell proliferation by regulating cell cycle progression and accelerates neointimal formation after arterial injury in mice

in Cardiovascular and Smooth Muscle Pharmacology

Gengqiao Wang
Peng Zhao
Chuanzheng Yin
Xichuan Zheng
Yuhang Xie
Xuan Li
Dan Shang
Shuyu Shao
Hao Chen
Li Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1392352

2,725 views
2 citations

Review

Published on 02 Aug 2024

Cross-talks between perivascular adipose tissue and neighbors: multifaceted nature of nereids

in Cardiovascular and Smooth Muscle Pharmacology

Yujuan Li
Zhang Chen
Ying Xiao
Xinzhi Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1442086

3,127 views
4 citations

Review

Published on 01 Aug 2024

The relationship of redox signaling with the risk for atherosclerosis

in Cardiovascular and Smooth Muscle Pharmacology

Sujuan Lei
Chen Liu
Tian-xiang Zheng
Wenguang Fu
Mei-zhou Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1430293

2,942 views
4 citations

Original Research

Published on 01 Aug 2024

Exploiting the anti-fibrotic effects of statins on thoracic aortic aneurysm progression: results from a meta-analysis and experimental data

in Cardiovascular and Smooth Muscle Pharmacology

Veronika A. Myasoedova
Sara Rega
Vincenza Valerio
Donato Moschetta
Ilaria Massaiu
Giorgia Bonalumi
Giampiero Esposito
Valentina Rusconi
Francesca Bertolini
Gianluca Lorenzo Perrucci

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1426982

3,647 views
2 citations

Review

Published on 31 Jul 2024

NLRP3 inflammasome in atherosclerosis: Mechanisms and targeted therapies

in Cardiovascular and Smooth Muscle Pharmacology

Pengfei Chen
Xia Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1430236

8,326 views
15 citations

Original Research

Published on 31 Jul 2024

Activation of PERK/eIF2α/ATF4/CHOP branch of endoplasmic reticulum stress response and cooperation between HIF-1α and ATF4 promotes Daprodustat-induced vascular calcification

in Cardiovascular and Smooth Muscle Pharmacology

Andrea Tóth
Gréta Lente
Dávid Máté Csiki
Enikő Balogh
Árpád Szöőr
Béla Nagy
Viktória Jeney

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1399248

5,990 views
13 citations

1,410 articles

articles

Inhibition of the RIP3/MLKL/TRPM7 necroptotic pathway ameliorates diabetes mellitus-induced erectile dysfunction by reducing cell death, fibrosis, and inflammation

Role of naringin in the treatment of atherosclerosis

Generation of a medicine food homology formula and its likely mechanism in treatment of microvascular angina

Effect of different single and combined antihypertensive drug regimens on the mortality of critical care patients

Tirzepatide’s innovative applications in the management of type 2 diabetes and its future prospects in cardiovascular health

Editorial: Design of novel inhibitors for ischemia/reperfusion injury targeting ferroptosis

Regulation mechanism of microRNAs in cardiac cells-derived exosomes in cell crosstalk

Suppression of NLRP3 inflammasome orchestrates the protective efficacy of tiron against isoprenaline-induced myocardial injury

Advancements in understanding cardiotoxicity of EGFR- TKIs in non-small cell lung cancer treatment and beyond

Puerarin attenuates myocardial ischemic injury and endoplasmic reticulum stress by upregulating the Mzb1 signal pathway

Impact of β-blockers on in-hospital mortality in patients with heart failure: a retrospective propensity-score matched analysis based on MIMIC-IV database

Editorial: Diabetes and cardiovascular disease: new therapeutic interventions

Association between acetaminophen administration and outcomes in critically ill patients with gout and hypertension

11-Hydroxyeicosatetraenoics induces cellular hypertrophy in an enantioselective manner

Reliability of Metformin’s protective effects against doxorubicin-induced cardiotoxicity: a meta-analysis of animal studies

Time-restricted eating, the clock ticking behind the scenes

Alchemilla vulgaris modulates isoproterenol-induced cardiotoxicity: interplay of oxidative stress, inflammation, autophagy, and apoptosis

Comprehensive mendelian randomization reveals atrial fibrillation-breast cancer relationship and explores common druggable targets

KIF11 promotes vascular smooth muscle cell proliferation by regulating cell cycle progression and accelerates neointimal formation after arterial injury in mice

Cross-talks between perivascular adipose tissue and neighbors: multifaceted nature of nereids

The relationship of redox signaling with the risk for atherosclerosis

Exploiting the anti-fibrotic effects of statins on thoracic aortic aneurysm progression: results from a meta-analysis and experimental data

NLRP3 inflammasome in atherosclerosis: Mechanisms and targeted therapies

Activation of PERK/eIF2α/ATF4/CHOP branch of endoplasmic reticulum stress response and cooperation between HIF-1α and ATF4 promotes Daprodustat-induced vascular calcification