Frontiers in Pharmacology | Cardiovascular and Smooth Muscle Pharmacology

Original Research

Accepted on 14 Nov 2025

Gut Microbiota-Dependent Anti-Inflammatory Mechanisms of Berberine in Ameliorating Hypertension: Role of SCFAs, LPS Reduction, and STAT3 Signaling

in Cardiovascular and Smooth Muscle Pharmacology

Wang Shanshan
Yaqian Hu
Xin Li
Yanhua Ou
Jinling Chen
Chen Yuhan
Jingyi Chen
Kunran Bai
Fangwen Xu
Xingyi Wang

Frontiers in Pharmacology

115 views

General Commentary

Accepted on 12 Nov 2025

Commentary: Hyperoside alleviates myocardial ischemia-reperfusion injury in heart transplantation by promoting mitochondrial fusion via activating the Stat3-Tom70-Opa1 pathway

in Cardiovascular and Smooth Muscle Pharmacology

Qin Yang
Yingjie Liu
Xinzheng Tang

Frontiers in Pharmacology

Original Research

Accepted on 10 Nov 2025

Association between Ranolazine therapy and cognitive decline in elderly patients with ischemic heart disease

in Cardiovascular and Smooth Muscle Pharmacology

Giandomenico Severini
Giuseppe Armentaro
Velia Cassano
Valentino Condoleo
Carlo Alberto Pastura
Alberto Panza
Carlo Fuoco
Sofia Miceli
Teresa Vanessa Fiorentino
Maria Perticone

Frontiers in Pharmacology

Review

Accepted on 10 Nov 2025

Echocardiographic assessment and new advances of right ventricle function in rats with pulmonary hypertension

in Cardiovascular and Smooth Muscle Pharmacology

Weijie Wang
Ming Ren
Dianxiang Lu

Frontiers in Pharmacology

Review

Published on 10 Nov 2025

The unmet promise: a critical review of antioxidant strategies in myocardial ischemia-reperfusion injury and the path towards precision medicine

in Cardiovascular and Smooth Muscle Pharmacology

Hao Chen
Yutao Tang
Pan Ren
Wenbin Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1693441

584 views

Original Research

Published on 10 Nov 2025

A novel bioactive peptide-peptoid hybrid of alpha-calcitonin gene-related peptide protects against pressure-overload induced heart failure

in Cardiovascular and Smooth Muscle Pharmacology

Ambrish Kumar
Sarah Deloach
Lernix Williams
Donald J. DiPette
Jay D. Potts

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1692472

664 views

Case Report

Published on 07 Nov 2025

Rifampicin-induced challenges in managing endocrine hypertension and primary aldosteronism: a case report and literature review

in Cardiovascular and Smooth Muscle Pharmacology

Xiaoxiao Song
Minyue Jia
Hanxiao Yu
Zhichao Dong
Kai Cheok
Xin Pan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1678430

366 views

Original Research

Accepted on 05 Nov 2025

The potential mechanism of Celastrol attenuating atherosclerosis by promoting macrophage autophagy via AMPK/ULK1 Pathway

in Cardiovascular and Smooth Muscle Pharmacology

Jiao Li
Yanrong Zhao
Yanfang Qi
Yue Liu
Linlin Fang
Zhenying Zhou
Liping Wei
Qi Li

Frontiers in Pharmacology

139 views

Review

Accepted on 03 Nov 2025

Endoplasmic Reticulum Oxidoreductin 1α as a Potential Therapeutic Target in Diseases: From Oxidative Protein Folding to Pathophysiological Mechanisms

in Cardiovascular and Smooth Muscle Pharmacology

he fang
Ge Xiaoyue
Liu xiaohui

Frontiers in Pharmacology

Original Research

Published on 31 Oct 2025

Agonizing GABABR suppresses GLP-1RA’s chronotropic effect and reduces post-myocardial infarction arrhythmogenesis

in Cardiovascular and Smooth Muscle Pharmacology

Run Qi
Zhang Jingjing
Gu Hongchang
Li Chenyu
Hu He
Li Juan
Zhao Yuqin
Wu Xiaolin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1616181

2,233 views

Review

Accepted on 30 Oct 2025

Targeting L-arginine/NO/cGMP/KATP pathway by phytochemicals: Therapeutic applications and clinical perspectives

in Cardiovascular and Smooth Muscle Pharmacology

Seyede Zahra Hosseini
Fatemeh Abbaszadeh
Seyede Darya Alavi
Mohammad Mehdi Gravandi
Roshanak Amirian
Sajad Fakhri
Javier Echeverria

Frontiers in Pharmacology

120 views

Original Research

Published on 30 Oct 2025

Efficacy and influencing factors analysis of SGLT2 inhibitors in treating heart failure following acute myocardial infarction

in Cardiovascular and Smooth Muscle Pharmacology

Haiping Du
Hui Xu
Jinwei Bao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1693420

674 views

Original Research

Published on 27 Oct 2025

Risk of post-polypectomy bleeding and thromboembolic events during colonoscopy in patients on continued or interrupted antiplatelet therapy: a pooled analysis

in Cardiovascular and Smooth Muscle Pharmacology

Nan-Nan Shen
Jun-Hong Ma
Hua Qian
Yong-Ping Fu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1660871

411 views

Original Research

Published on 24 Oct 2025

Quantitative assessment of the usability of electromechanical human-based modelling and simulation to replace Langendorff isolated rabbit heart experiments in the preclinical setting

in Cardiovascular and Smooth Muscle Pharmacology

Maxx Holmes
Hector Martinez-Navarro
Marcel Mohr
Jean-Marie Chambard
Veronique Ballet
Eva Vermersch
Ambroise Garry
Friedemann Schmidt
Blanca Rodriguez

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1671199

984 views

Original Research

Accepted on 23 Oct 2025

Terminal complement inhibition in atypical haemolytic uremic syndrome: a single-centre experience

in Cardiovascular and Smooth Muscle Pharmacology

Valentin Dumitrel Mocanu
Bogdan M Sorohan
Bogdan Obrișcă
Elena Georgia Micu
Roxana A Jurubiță
Sonia Bălănică
Cristina S Capușă
Gabriel Mircescu
Gener Ismail

Frontiers in Pharmacology

601 views

Original Research

Published on 21 Oct 2025

The interaction of AB-680, a CD73 inhibitor, with NBTI, a nucleoside transporter inhibitor, on the adenosinergic control of atrial contractility

in Cardiovascular and Smooth Muscle Pharmacology

Ignac Ovari
Agnes Boglarka Brezniczky
Attila Laczovics
Ervin Berényi
Tamas Erdei
Oluwatofunmi Ojo
Bence Hornok
Bela Juhasz
Zoltan Szilvassy
Judit Zsuga

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1683950

741 views