Frontiers in Pharmacology | Cardiovascular and Smooth Muscle Pharmacology

Original Research

Published on 31 Mar 2025

Mendelian randomization study highlights the role of hematological traits on Type-2 diabetes mellitus in African ancestry individuals

in Cardiovascular and Smooth Muscle Pharmacology

Chisom Soremekun
Daudi Jjingo
David Kateete
Oyekanmi Nash
Dorothea Nitsch
Moffat Nyirenda
Dipender Gill
Eleftheria Zeggini
Harald Grallert
Annette Peters

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1436972

305 views

Original Research

Accepted on 28 Mar 2025

α-Mangostin Prevents Diabetic Cardiomyopathy by Inhibiting Oxidative Damage and Lipotoxicity through the AKT-FOXO1-CD36 Pathway

in Cardiovascular and Smooth Muscle Pharmacology

Xue Bai
Ziqian Zhang
Miao Zhang
Jiaojiao Xu
Keting Dong
Qian Du
Lei Chen
Ping Ma
Jianhong Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1566311

Original Research

Published on 28 Mar 2025

Vascular smooth muscle cell-derived SO2 sulphenylated interferon regulatory factor 1 to inhibit VSMC senescence

in Cardiovascular and Smooth Muscle Pharmacology

Bingquan Qiu
Shangyue Zhang
Shuang Ge
Zhengyu Yu
Deqing Wang
Kun Li
Xiaoqi Yu
Chaoshu Tang
Junbao Du
Hongfang Jin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1516885

267 views

Review

Published on 28 Mar 2025

Diuretics: a review of the pharmacology and effects on glucose homeostasis

in Cardiovascular and Smooth Muscle Pharmacology

Mauricio Di Fulvio
Yakshkumar Dilipbhai Rathod
Shorooq Khader

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1513125

393 views

Original Research

Published on 28 Mar 2025

Butylphthalide reduces plaque burden and improves neurological function in carotid atherosclerotic disease: a pooled analysis

in Cardiovascular and Smooth Muscle Pharmacology

Jia Yang
Xinhao Pei
Jianxin Qiang
Lijuan Li
Yanping Liu
Panpan Hao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1460338

406 views

Review

Published on 27 Mar 2025

Carfilzomib in multiple myeloma: unraveling cardiac toxicities - from mechanisms to diagnosis and management

in Cardiovascular and Smooth Muscle Pharmacology

Yi Gao
Di Zhou
Xue Bai
Yunjie Wang
Chenchen Wang
Lintao Bi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1570017

204 views

Original Research

Published on 26 Mar 2025

Cre recombinase affects calcium dynamics already in young mice

in Cardiovascular and Smooth Muscle Pharmacology

János Levin Liffers
Jan Peter Reinhardt
Matthias Dodo Seidl
Uwe Kirchhefer
Frank Ulrich Müller
Jan Sebastian Schulte

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558573

251 views

Original Research

Published on 26 Mar 2025

Phenylephrine and the risk of atrial fibrillation in critically ill patients: a multi-centre study from eICU database

in Cardiovascular and Smooth Muscle Pharmacology

ZhiMing Huang
Weichao Li
WeiXian Xie
Gu xun-hu
Heng Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1478961

255 views

Editorial

Published on 25 Mar 2025

Editorial: Mendelian randomization and cardiovascular remodeling

in Cardiovascular and Smooth Muscle Pharmacology

Jianxin Qiang
Jia Yang
Yanwu Liu
Ji Zhang
Hao Sun
Lijuan Li
Duo Wang
Yanping Liu
Panpan Hao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1593325

273 views

Review

Published on 21 Mar 2025

Impact of plant-derived antioxidants on heart aging: a mechanistic outlook

in Cardiovascular and Smooth Muscle Pharmacology

Muneer Ahmed Khoso
Heng Liu
Tong Zhao
Wenjie Zhao
Qiang Huang
Zeqi Sun
Khuzin Dinislam
Chen Chen
Lingyi Kong
Yong Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1524584

730 views

Original Research

Published on 20 Mar 2025

Semaglutide attenuates myocardial ischemia-reperfusion injury by inhibiting ferroptosis of cardiomyocytes via activation of PKC-S100A9 axis

in Cardiovascular and Smooth Muscle Pharmacology

Yan Liu
Zixuan Li
Xinhe Xu
Yan Zou
Miaomiao Zhang
Yingyu Chen
Wenwu Zhu
Bing Han

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1529652

573 views

Review

Published on 20 Mar 2025

Takeda G protein–coupled receptor 5 (TGR5): an attractive therapeutic target for aging-related cardiovascular diseases

in Cardiovascular and Smooth Muscle Pharmacology

Yufeng He
Siqi Liu
Yali Zhang
Yumei Zuo
Keming Huang
Li Deng
Bin Liao
Yi Zhong
Jian Feng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1493662

458 views

Original Research

Published on 19 Mar 2025

Impact of statin use on short- and long-term outcomes in patients with sepsis-induced myocardial injury: insights from the MIMIC-IV database

in Cardiovascular and Smooth Muscle Pharmacology

Yuan Liu
Jijiang Chen
Yehao Yuan
Pingping Niu
Mengyi Wu
Baoling Shang
Weihui Lu
Xu Zou
Gengzhen Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1520107

449 views

Original Research

Published on 17 Mar 2025

In silico predictions of drug-induced changes in human cardiac contractility align with experimental recordings

in Cardiovascular and Smooth Muscle Pharmacology

Cristian Trovato
Stefano Longobardi
Elisa Passini
Kylie A. Beattie
Maxx Holmes
Khuram W. Chaudhary
Eric I. Rossman
Blanca Rodriguez

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1500668

948 views
1 citation

Review

Published on 17 Mar 2025

The role of Perilipin 5 in pathological myocardial remodeling

in Cardiovascular and Smooth Muscle Pharmacology

Danzeng Dunzhu
Gao Han
Qin Shanshan
Shangshi Li
Jiali Yang
Jian He
Siyu Gou
Gang Dong
Chunrong Jiang
Jun Hou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1526494

506 views

Original Research

Published on 17 Mar 2025

The relationship between remnant cholesterol and young-onset myocardial infarction in patients with type 2 diabetes: a retrospective study

in Cardiovascular and Smooth Muscle Pharmacology

Yajie Gao
Tianjiao Lei
Peizhu Dang
Yongxin Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1512662

396 views