Frontiers in Pharmacology | Cardiovascular and Smooth Muscle Pharmacology

Original Research

Published on 02 Sep 2025

The action of ginsenoside Rg1 in patients with carotid atherosclerosis: a controlled clinical trial

in Cardiovascular and Smooth Muscle Pharmacology

Xu Fang
Xuan Ma
Man Zhang
Li Zhang
Xu He
Shilei Liu
Yinsong Dong
Yan Li
Junzi Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1638359

2,214 views

Original Research

Published on 01 Sep 2025

Resveratrol ameliorates osteogenic differentiation, calcification, and apoptosis of VSMCs through regulating JNK/Bax signaling

in Cardiovascular and Smooth Muscle Pharmacology

Menglin Hou
Hui Wang
Junmei Cheng
Xuyan Duan
Min Ren
Yong Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1631039

2,019 views

Original Research

Published on 25 Aug 2025

Risk prediction of mechanical complications in acute myocardial infarction patients with prior malignancy

in Cardiovascular and Smooth Muscle Pharmacology

Changying Zhao
Chuqing Yang
Yang Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1643770

1,659 views

Case Report

Published on 22 Aug 2025

Loperamide poisoning resulting in death: a case report and literature review

in Cardiovascular and Smooth Muscle Pharmacology

Bowen Wang
Zhan Zhang
Ke Chen
Zhongyang Du
Tianchen Zhang
Ping Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1597869

4,145 views
1 citation

Case Report

Published on 22 Aug 2025

Acute myocardial infarction induced by avatrombopag: a case report

in Cardiovascular and Smooth Muscle Pharmacology

Gou Junqi
Liu Chaohui
Lang Mingjian
Yao Fengyou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1618693

2,004 views

Brief Research Report

Published on 21 Aug 2025

Improved survival and neurological outcomes with lysophosphatidylcholine supplementation in severe cardiac arrest model

in Cardiovascular and Smooth Muscle Pharmacology

Muhammad Shoaib
Mitsuaki Nishikimi
Rishabh C. Choudhary
Tsukasa Yagi
Kei Hayashida
Tai Yin
Blanca B. Espin
Lance B. Becker
Junhwan Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1587776

1,349 views

Original Research

Published on 21 Aug 2025

Inverse association between pre-high-altitude potassium levels and coronary microvascular disease at high altitude: a case-control study

in Cardiovascular and Smooth Muscle Pharmacology

Yu Chen
Yong Ren
Xin Zhang
Wen-Bao Zhou
Wen-Tao Zhang
Juan Lv
Xi-Yang Rao
Rui-Xi Zi
Si-Jie Wang
Li-Sha Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1659041

1,335 views

Mini Review

Published on 20 Aug 2025

Comparative effects of moderate and high-intensity training on immune activation in myocarditis: a review of preclinical and clinical evidence

in Cardiovascular and Smooth Muscle Pharmacology

Bartolo Ferraro
Cristina Alejandra Buela Alvarado
Jonas Mink
Ludwig T. Weckbach

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1643056

2,073 views

Original Research

Published on 20 Aug 2025

Cluster analysis of hotspots and research trends of epirubicin-induced cardiotoxicity: a bibliometric study

in Cardiovascular and Smooth Muscle Pharmacology

Dongning He
Wenjuan Wang
Xigang Luo
Yadi Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1616162

1,674 views
2 citations

Case Report

Published on 14 Aug 2025

Case Report: Micronized purified flavonoid fraction [Daflon]-induced bradycardia

in Cardiovascular and Smooth Muscle Pharmacology

Jhennyfer Aline Lima Rodrigues
Jonathas Pereira das Graças
Gledson de Oliveira Machado

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1612315

3,237 views

Correction

Published on 13 Aug 2025

Correction: Alchemilla vulgaris modulates isoproterenol-induced cardiotoxicity: interplay of oxidative stress, inflammation, autophagy, and apoptosis

in Cardiovascular and Smooth Muscle Pharmacology

Nuha Anajirih
Ahmed Abdeen
Ehab S. Taher
Afaf Abdelkader
Hoda A. Abd-Ellatieff
Mahmoud S. Gewaily
Nashwa E. Ahmed
Rasha H. Al-Serwi
Safwa M. Sorour
Heba M. Abdelkareem

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1650419

983 views

Original Research

Published on 11 Aug 2025

The identification of adenylyl cyclase modulators as potential receptors for 6-nitrodopamine in human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes and their relevance in heart inotropism

in Cardiovascular and Smooth Muscle Pharmacology

Irene Cipollone
Vittoria Monaco
José Britto-Júnior
Antonio Tiago Lima
Edson Antunes
Andre Sampaio Pupo
Ilaria Iacobucci
Flora Cozzolino
Maria Monti
Silvia Parisi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1597035

2,350 views
2 citations

Review

Published on 04 Aug 2025

Long-acting relaxin analogues: a novel tool in cardiology

in Cardiovascular and Smooth Muscle Pharmacology

Łukasz Wołowiec
Albert Jaśniak
Joanna Osiak-Gwiazdowska
Daria Czaplińska
Agata Szymczak
Julia Anna Pęcherz
Grzegorz Grześk

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1626469

4,077 views

Brief Research Report

Published on 31 Jul 2025

Comparative analysis of furosemide and torsemide efficacy in 24 hours of acute heart failure admission

in Cardiovascular and Smooth Muscle Pharmacology

Małgorzata Małek-Elikowska
Andrzej Szyszka
Julita Fedorowicz
Rafał Dankowski
Cyntia Szymańska
Artur Baszko

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1643077

2,357 views

Original Research

Published on 29 Jul 2025

HDL attenuates Ang II–AT1R–EGFR signaling and reverses vascular remodeling in spontaneously hypertensive rats

in Cardiovascular and Smooth Muscle Pharmacology

Aishah Al-Jarallah
Samah Kalakh
Saghir Akhtar
Mariam H. M. Yousif

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1617420

1,541 views

Original Research

Published on 28 Jul 2025

Exploring the biological basis for the identification of different syndromes in ischemic heart failure based on joint multi-omics analysis

in Cardiovascular and Smooth Muscle Pharmacology

Yilin Zhang
Jingjing Wei
Lijie Qiao
Rui Yu
Hongjie Ren
Anshe Zhao
Yang Sun
Aolong Wang
Bin Li
Xinlu Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1641422

3,100 views
2 citations

Original Research

Published on 25 Jul 2025

What are the best clinical management strategies for cardiomyopathy? an umbrella review of systematic reviews and meta-analyses

in Cardiovascular and Smooth Muscle Pharmacology

Wanru Cheng
Jing Wang
Jie Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1544121

1,685 views

Review

Published on 23 Jul 2025

Mechanisms of beneficial effects of DPP-4 inhibitors as a promising perspective for the prevention/treatment of the disruption of cardio-cerebrovascular homeostasis

in Cardiovascular and Smooth Muscle Pharmacology

Katarina Tomović Pavlović
Marko Anderluh
Andrija Šmelcerović

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1642333

2,847 views
1 citation

Case Report

Published on 18 Jul 2025

Case Report: Third-degree atrioventricular block and respiratory failure caused by clozapine poisoning

in Cardiovascular and Smooth Muscle Pharmacology

Qiaoxin Tian
Ruikai Shang
Yuru Liu
Hongyu Liu
Yingying Zheng
Xiangdong Jian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1572578

1,616 views
1 citation

Case Report

Published on 15 Jul 2025

A case report of ‘Two-Hit’ digenic mutations in PAH: role of PADN in management

in Cardiovascular and Smooth Muscle Pharmacology

Zai-qiang Zhang
Zhou-qiang Qin
Sheng-kui Zhu
Yu-hong Zuo
Jia-wang Ding

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1601777

1,349 views

Original Research

Published on 14 Jul 2025

Fc-Elabela mitigates heart failure without liver and renal toxicity in mice

in Cardiovascular and Smooth Muscle Pharmacology

Huifen Zhou
Da-Wei Gong
Ling Chen
Hui Chen
Quan Wang
Mustajab Ullah
Saleem Ahmad
Ishtiaq Jeelani
Qingbin Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1555728

1,789 views
3 citations

Original Research

Published on 14 Jul 2025

Gastrodin reduces myocardial ischemia/reperfusion injury via transgelin2/CNPase-mediated apoptosis regulation

in Cardiovascular and Smooth Muscle Pharmacology

Changyan Li
Peng Rao
Xiang Liu
Lin Yang
Yongliang Jiang
Gaosheng Yin
Shuangxiu Li
Ping Yang
Lin Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1604408

2,082 views

Case Report

Published on 11 Jul 2025

Low-molecular-weight heparin-induced thrombocytopenia with multisite embolism: successful management with argatroban and dabigatran – a case report and literature review

in Cardiovascular and Smooth Muscle Pharmacology

Huixin Zhao
Xiaowan Tang
Xitao Song

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1573840

2,305 views

Original Research

Published on 10 Jul 2025

Calycosin suppresses the activating effect of granulocyte-macrophage-colony-stimulating factor-producing T helper cells on macrophages in experimental atherosclerosis

in Cardiovascular and Smooth Muscle Pharmacology

Xiaofang Xiong
Wei Huang
Xuexue Yang
Xun Wang
Beibei Wu
Dongsheng Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1607349

1,952 views

1,408 articles

articles

The action of ginsenoside Rg1 in patients with carotid atherosclerosis: a controlled clinical trial

Resveratrol ameliorates osteogenic differentiation, calcification, and apoptosis of VSMCs through regulating JNK/Bax signaling

Risk prediction of mechanical complications in acute myocardial infarction patients with prior malignancy

Loperamide poisoning resulting in death: a case report and literature review

Acute myocardial infarction induced by avatrombopag: a case report

Improved survival and neurological outcomes with lysophosphatidylcholine supplementation in severe cardiac arrest model

Inverse association between pre-high-altitude potassium levels and coronary microvascular disease at high altitude: a case-control study

Comparative effects of moderate and high-intensity training on immune activation in myocarditis: a review of preclinical and clinical evidence

Cluster analysis of hotspots and research trends of epirubicin-induced cardiotoxicity: a bibliometric study

Case Report: Micronized purified flavonoid fraction [Daflon]-induced bradycardia

Correction: Alchemilla vulgaris modulates isoproterenol-induced cardiotoxicity: interplay of oxidative stress, inflammation, autophagy, and apoptosis

The identification of adenylyl cyclase modulators as potential receptors for 6-nitrodopamine in human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes and their relevance in heart inotropism

Long-acting relaxin analogues: a novel tool in cardiology

Comparative analysis of furosemide and torsemide efficacy in 24 hours of acute heart failure admission

HDL attenuates Ang II–AT1R–EGFR signaling and reverses vascular remodeling in spontaneously hypertensive rats

Exploring the biological basis for the identification of different syndromes in ischemic heart failure based on joint multi-omics analysis

What are the best clinical management strategies for cardiomyopathy? an umbrella review of systematic reviews and meta-analyses

Mechanisms of beneficial effects of DPP-4 inhibitors as a promising perspective for the prevention/treatment of the disruption of cardio-cerebrovascular homeostasis

Case Report: Third-degree atrioventricular block and respiratory failure caused by clozapine poisoning

A case report of ‘Two-Hit’ digenic mutations in PAH: role of PADN in management

Fc-Elabela mitigates heart failure without liver and renal toxicity in mice

Gastrodin reduces myocardial ischemia/reperfusion injury via transgelin2/CNPase-mediated apoptosis regulation

Low-molecular-weight heparin-induced thrombocytopenia with multisite embolism: successful management with argatroban and dabigatran – a case report and literature review

Calycosin suppresses the activating effect of granulocyte-macrophage-colony-stimulating factor-producing T helper cells on macrophages in experimental atherosclerosis