Frontiers in Pharmacology | Cardiovascular and Smooth Muscle Pharmacology

Original Research

Published on 23 Apr 2025

Clusterin ameliorates diabetic atherosclerosis by suppressing macrophage pyroptosis and activation

in Cardiovascular and Smooth Muscle Pharmacology

Lingling Xuan
Lulu Ren
Xiaoxu Kang
Rui Chang
Wen Zhang
Lili Gong
Lihong Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1536132

1,343 views

Original Research

Published on 17 Apr 2025

α-Mangostin prevents diabetic cardiomyopathy by inhibiting oxidative damage and lipotoxicity through the AKT–FOXO1–CD36 pathway

in Cardiovascular and Smooth Muscle Pharmacology

Xue Bai
Ziqian Zhang
Miao Zhang
Jiaojiao Xu
Keting Dong
Qian Du
Lei Chen
Ping Ma
Jianhong Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1566311

2,165 views

Review

Published on 17 Apr 2025

NLRP3 inflammasome as a therapeutic target in doxorubicin-induced cardiotoxicity: role of phytochemicals

in Cardiovascular and Smooth Muscle Pharmacology

Xiao-Peng Zhao
Lian Duan
Qian-Ru Zhao
Xing Lv
Nai-Yuan Tian
Sheng-Lei Yang
Kun Dong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1567312

1,445 views
1 citation

Mini Review

Published on 15 Apr 2025

The functional significance of vascular DNA hypermethylation in atherosclerosis: a historical perspective

in Cardiovascular and Smooth Muscle Pharmacology

Silvio Zaina

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562674

1,261 views

Original Research

Published on 14 Apr 2025

Cardiac protection of wogonin in mice with pulmonary fibrosis by regulating Sirt1/ γ-H2AX pathway

in Cardiovascular and Smooth Muscle Pharmacology

Libo Wang
Fei Lin
Runran Miao
Tianhao Zhao
Yuan Liu
Lin Yang
Min Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1551141

1,386 views

Review

Published on 10 Apr 2025

Effects of Chinese Medicine on modulating interleukin-17-regulated macrophages in coronary heart disease

in Cardiovascular and Smooth Muscle Pharmacology

Qingqing Liu
Peizhong Liu
Chuangpeng Li
Zhen Zhao
Dawei Wang
Qing Liu
Huawei Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1499786

1,383 views

Review

Published on 04 Apr 2025

Acacetin as a natural cardiovascular therapeutic: mechanisms and preclinical evidence

in Cardiovascular and Smooth Muscle Pharmacology

Zihe Zhou
Tao Li
Helin Qin
Xinyu Wang
Shanshan He
Zhongcai Fan
Qiang Ye
Yanfei Du

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1493981

3,234 views

Review

Published on 02 Apr 2025

Traditional Chinese medicine compounds modulate signaling pathways to improve cardiac-related pathology

in Cardiovascular and Smooth Muscle Pharmacology

Luwen Zhang
Wei Wang
Xincan Liu
Kuipo Yan
Qiang Li
Ming Li
Chunying Li
Yanxin Li
Lei Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1499060

1,043 views

Original Research

Published on 02 Apr 2025

LncRNA MEG3 exacerbates diabetic cardiomyopathy via activating pyroptosis signaling pathway

in Cardiovascular and Smooth Muscle Pharmacology

Shengnan Zhuo
Yifeng Liu
Siyuan Wang
Zhuoling Chen
Xuran Shi
Yangjunna Zhang
Dengfeng Xu
Jingjin Hu
Yin Wang
Xuefeng Qu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1538059

1,553 views

Original Research

Published on 01 Apr 2025

Deciphering the causality of gut microbiota, circulating metabolites and heart failure: a mediation mendelian

in Cardiovascular and Smooth Muscle Pharmacology

Xueqing Guan
Chaonan Sun
Jianyao Su
Zhijun Sun
Cheng Cheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1531384

1,561 views

Original Research

Published on 31 Mar 2025

Mendelian randomization study highlights the role of hematological traits on Type-2 diabetes mellitus in African ancestry individuals

in Cardiovascular and Smooth Muscle Pharmacology

Chisom Soremekun
Daudi Jjingo
David Kateete
Oyekanmi Nash
Dorothea Nitsch
Moffat Nyirenda
Dipender Gill
Eleftheria Zeggini
Harald Grallert
Annette Peters

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1436972

1,865 views

Original Research

Published on 28 Mar 2025

Vascular smooth muscle cell-derived SO2 sulphenylated interferon regulatory factor 1 to inhibit VSMC senescence

in Cardiovascular and Smooth Muscle Pharmacology

Bingquan Qiu
Shangyue Zhang
Shuang Ge
Zhengyu Yu
Deqing Wang
Kun Li
Xiaoqi Yu
Chaoshu Tang
Junbao Du
Hongfang Jin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1516885

1,558 views

Review

Published on 28 Mar 2025

Diuretics: a review of the pharmacology and effects on glucose homeostasis

in Cardiovascular and Smooth Muscle Pharmacology

Mauricio Di Fulvio
Yakshkumar Dilipbhai Rathod
Shorooq Khader

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1513125

4,276 views

Original Research

Published on 28 Mar 2025

Butylphthalide reduces plaque burden and improves neurological function in carotid atherosclerotic disease: a pooled analysis

in Cardiovascular and Smooth Muscle Pharmacology

Jia Yang
Xinhao Pei
Jianxin Qiang
Lijuan Li
Yanping Liu
Panpan Hao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1460338

1,005 views

Review

Published on 27 Mar 2025

Carfilzomib in multiple myeloma: unraveling cardiac toxicities - from mechanisms to diagnosis and management

in Cardiovascular and Smooth Muscle Pharmacology

Yi Gao
Di Zhou
Xue Bai
Yunjie Wang
Chenchen Wang
Lintao Bi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1570017

1,639 views

Original Research

Published on 26 Mar 2025

Cre recombinase affects calcium dynamics already in young mice

in Cardiovascular and Smooth Muscle Pharmacology

János Levin Liffers
Jan Peter Reinhardt
Matthias Dodo Seidl
Uwe Kirchhefer
Frank Ulrich Müller
Jan Sebastian Schulte

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558573

1,089 views