Frontiers in Pharmacology | Cardiovascular and Smooth Muscle Pharmacology

Original Research

Published on 01 Apr 2025

Deciphering the causality of gut microbiota, circulating metabolites and heart failure: a mediation mendelian

in Cardiovascular and Smooth Muscle Pharmacology

Xueqing Guan
Chaonan Sun
Jianyao Su
Zhijun Sun
Cheng Cheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1531384

2,832 views
1 citation

Original Research

Published on 31 Mar 2025

Mendelian randomization study highlights the role of hematological traits on Type-2 diabetes mellitus in African ancestry individuals

in Cardiovascular and Smooth Muscle Pharmacology

Chisom Soremekun
Daudi Jjingo
David Kateete
Oyekanmi Nash
Dorothea Nitsch
Moffat Nyirenda
Dipender Gill
Eleftheria Zeggini
Harald Grallert
Annette Peters

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1436972

3,111 views

Review

Published on 28 Mar 2025

Diuretics: a review of the pharmacology and effects on glucose homeostasis

in Cardiovascular and Smooth Muscle Pharmacology

Mauricio Di Fulvio
Yakshkumar Dilipbhai Rathod
Shorooq Khader

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1513125

9,834 views
1 citation

Original Research

Published on 28 Mar 2025

Vascular smooth muscle cell-derived SO2 sulphenylated interferon regulatory factor 1 to inhibit VSMC senescence

in Cardiovascular and Smooth Muscle Pharmacology

Bingquan Qiu
Shangyue Zhang
Shuang Ge
Zhengyu Yu
Deqing Wang
Kun Li
Xiaoqi Yu
Chaoshu Tang
Junbao Du
Hongfang Jin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1516885

3,189 views

Original Research

Published on 28 Mar 2025

Butylphthalide reduces plaque burden and improves neurological function in carotid atherosclerotic disease: a pooled analysis

in Cardiovascular and Smooth Muscle Pharmacology

Jia Yang
Xinhao Pei
Jianxin Qiang
Lijuan Li
Yanping Liu
Panpan Hao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1460338

1,927 views

Review

Published on 27 Mar 2025

Carfilzomib in multiple myeloma: unraveling cardiac toxicities - from mechanisms to diagnosis and management

in Cardiovascular and Smooth Muscle Pharmacology

Yi Gao
Di Zhou
Xue Bai
Yunjie Wang
Chenchen Wang
Lintao Bi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1570017

4,121 views
1 citation

Original Research

Published on 26 Mar 2025

Cre recombinase affects calcium dynamics already in young mice

in Cardiovascular and Smooth Muscle Pharmacology

János Levin Liffers
Jan Peter Reinhardt
Matthias Dodo Seidl
Uwe Kirchhefer
Frank Ulrich Müller
Jan Sebastian Schulte

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558573

2,155 views
1 citation

Original Research

Published on 26 Mar 2025

Phenylephrine and the risk of atrial fibrillation in critically ill patients: a multi-centre study from eICU database

in Cardiovascular and Smooth Muscle Pharmacology

ZhiMing Huang
Weichao Li
WeiXian Xie
Gu xun-hu
Heng Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1478961

2,147 views

Editorial

Published on 25 Mar 2025

Editorial: Mendelian randomization and cardiovascular remodeling

in Cardiovascular and Smooth Muscle Pharmacology

Jianxin Qiang
Jia Yang
Yanwu Liu
Ji Zhang
Hao Sun
Lijuan Li
Duo Wang
Yanping Liu
Panpan Hao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1593325

2,705 views

Review

Published on 21 Mar 2025

Impact of plant-derived antioxidants on heart aging: a mechanistic outlook

in Cardiovascular and Smooth Muscle Pharmacology

Muneer Ahmed Khoso
Heng Liu
Tong Zhao
Wenjie Zhao
Qiang Huang
Zeqi Sun
Khuzin Dinislam
Chen Chen
Lingyi Kong
Yong Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1524584

4,913 views
2 citations

Original Research

Published on 20 Mar 2025

Semaglutide attenuates myocardial ischemia-reperfusion injury by inhibiting ferroptosis of cardiomyocytes via activation of PKC-S100A9 axis

in Cardiovascular and Smooth Muscle Pharmacology

Yan Liu
Zixuan Li
Xinhe Xu
Yan Zou
Miaomiao Zhang
Yingyu Chen
Wenwu Zhu
Bing Han

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1529652

4,435 views
3 citations

Review

Published on 20 Mar 2025

Takeda G protein–coupled receptor 5 (TGR5): an attractive therapeutic target for aging-related cardiovascular diseases

in Cardiovascular and Smooth Muscle Pharmacology

Yufeng He
Siqi Liu
Yali Zhang
Yumei Zuo
Keming Huang
Li Deng
Bin Liao
Yi Zhong
Jian Feng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1493662

3,294 views
3 citations

Original Research

Published on 19 Mar 2025

Impact of statin use on short- and long-term outcomes in patients with sepsis-induced myocardial injury: insights from the MIMIC-IV database

in Cardiovascular and Smooth Muscle Pharmacology

Yuan Liu
Jijiang Chen
Yehao Yuan
Pingping Niu
Mengyi Wu
Baoling Shang
Weihui Lu
Xu Zou
Gengzhen Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1520107

4,744 views

Original Research

Published on 17 Mar 2025

In silico predictions of drug-induced changes in human cardiac contractility align with experimental recordings

in Cardiovascular and Smooth Muscle Pharmacology

Cristian Trovato
Stefano Longobardi
Elisa Passini
Kylie A. Beattie
Maxx Holmes
Khuram W. Chaudhary
Eric I. Rossman
Blanca Rodriguez

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1500668

3,294 views
6 citations

Original Research

Published on 17 Mar 2025

The relationship between remnant cholesterol and young-onset myocardial infarction in patients with type 2 diabetes: a retrospective study

in Cardiovascular and Smooth Muscle Pharmacology

Yajie Gao
Tianjiao Lei
Peizhu Dang
Yongxin Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1512662

1,893 views

Review

Published on 17 Mar 2025

The role of Perilipin 5 in pathological myocardial remodeling

in Cardiovascular and Smooth Muscle Pharmacology

Danzeng Dunzhu
Gao Han
Qin Shanshan
Shangshi Li
Jiali Yang
Jian He
Siyu Gou
Gang Dong
Chunrong Jiang
Jun Hou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1526494

2,941 views
1 citation

Original Research

Published on 17 Mar 2025

PD-1 inhibition disrupts collagen homeostasis and aggravates cardiac dysfunction through endothelial-fibroblast crosstalk and EndMT

in Cardiovascular and Smooth Muscle Pharmacology

Zejin Zhang
Zhenzhen Yan
Tao Yuan
Xiaona Zhao
Minghui Wang
Guoqing Liu
Lijun Gan
Wei Qin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1549487

3,495 views
1 citation

Original Research

Published on 13 Mar 2025

Bibliometric analysis of treatment modalities in calcific aortic valve stenosis

in Cardiovascular and Smooth Muscle Pharmacology

Yang He
Yue-Jiao Yang
Zhao-Jun Wang
Liang Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1431311

2,257 views
1 citation

Original Research

Published on 13 Mar 2025

Navarixin alleviates cardiac remodeling after myocardial infarction by decreasing neutrophil infiltration and the inflammatory response

in Cardiovascular and Smooth Muscle Pharmacology

Peikun Hu
Wei Liu
Jungang Huang
Yangfan Su
Huiqi Jiang
Qinyu Wu
Jun Tao
Shi Liang
Jun Lin
Junmeng Zheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1535703

2,274 views
3 citations

Original Research

Published on 11 Mar 2025

Metabolomics of the effects of Yishenjiangya granules in older adults with hypertension

in Cardiovascular and Smooth Muscle Pharmacology

Yongbo Ma
Yingying Liu
Li Zhuang
Xia Dai
Li Yao
Jie Yu
Lei Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1491935

1,334 views

Review

Published on 06 Mar 2025

Targeting miRNA with flavonoids: unlocking novel pathways in cardiovascular disease management

in Cardiovascular and Smooth Muscle Pharmacology

Arya Tjipta Prananda
Princella Halim
Rony Abdi Syahputra

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532986

2,638 views
4 citations

Review

Published on 06 Mar 2025

Potential therapeutic mechanisms of Draconis Resina in cardiovascular diseases-a narrative review

in Cardiovascular and Smooth Muscle Pharmacology

Jing Wang
Xiusong Tang
Peng Lan
Bin Liang
Yu Fang
Hongbo Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1531873

2,239 views

Review

Published on 04 Mar 2025

Berberine and its derivatives: mechanisms of action in myocardial vascular endothelial injury - a review

in Cardiovascular and Smooth Muscle Pharmacology

Wenhui Zhang
Siyi Guo
Jinjin Dou
Xiwu Zhang
Fan Shi
Chun Zhang
Huxiao Zhang
Xiaodong Lan
Yi Su

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1543697

3,277 views
3 citations

Review

Published on 28 Feb 2025

Effect of sodium-glucose Co-transporter 2 inhibitors on coronary microcirculation

in Cardiovascular and Smooth Muscle Pharmacology

Shaoxin Chen
Weiqian Ou
Shuguang Gan
Lixian Chen
Baohua Liu
Zhenhong Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1523727

2,873 views
3 citations

1,408 articles

articles

Deciphering the causality of gut microbiota, circulating metabolites and heart failure: a mediation mendelian

Mendelian randomization study highlights the role of hematological traits on Type-2 diabetes mellitus in African ancestry individuals

Diuretics: a review of the pharmacology and effects on glucose homeostasis

Vascular smooth muscle cell-derived SO2 sulphenylated interferon regulatory factor 1 to inhibit VSMC senescence

Butylphthalide reduces plaque burden and improves neurological function in carotid atherosclerotic disease: a pooled analysis

Carfilzomib in multiple myeloma: unraveling cardiac toxicities - from mechanisms to diagnosis and management

Cre recombinase affects calcium dynamics already in young mice

Phenylephrine and the risk of atrial fibrillation in critically ill patients: a multi-centre study from eICU database

Editorial: Mendelian randomization and cardiovascular remodeling

Impact of plant-derived antioxidants on heart aging: a mechanistic outlook

Semaglutide attenuates myocardial ischemia-reperfusion injury by inhibiting ferroptosis of cardiomyocytes via activation of PKC-S100A9 axis

Takeda G protein–coupled receptor 5 (TGR5): an attractive therapeutic target for aging-related cardiovascular diseases

Impact of statin use on short- and long-term outcomes in patients with sepsis-induced myocardial injury: insights from the MIMIC-IV database

In silico predictions of drug-induced changes in human cardiac contractility align with experimental recordings

The relationship between remnant cholesterol and young-onset myocardial infarction in patients with type 2 diabetes: a retrospective study

The role of Perilipin 5 in pathological myocardial remodeling

PD-1 inhibition disrupts collagen homeostasis and aggravates cardiac dysfunction through endothelial-fibroblast crosstalk and EndMT

Bibliometric analysis of treatment modalities in calcific aortic valve stenosis

Navarixin alleviates cardiac remodeling after myocardial infarction by decreasing neutrophil infiltration and the inflammatory response

Metabolomics of the effects of Yishenjiangya granules in older adults with hypertension

Targeting miRNA with flavonoids: unlocking novel pathways in cardiovascular disease management

Potential therapeutic mechanisms of Draconis Resina in cardiovascular diseases-a narrative review

Berberine and its derivatives: mechanisms of action in myocardial vascular endothelial injury - a review

Effect of sodium-glucose Co-transporter 2 inhibitors on coronary microcirculation